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Items: 42

1.

Analysis of Neutrophil Transmigration Through Epithelial Cell Monolayers.

Kirpotina LN, Kominsky DJ, Quinn MT, Swain SD.

Methods Mol Biol. 2020;2087:79-91. doi: 10.1007/978-1-0716-0154-9_6.

PMID:
31728984
2.

Slug and Snail have differential effects in directing colonic epithelial wound healing and partially mediate the restitutive effects of butyrate.

Swain SD, Grifka-Walk HN, Gripentrog J, Lehmann M, Deuling B, Jenkins B, Liss H, Blaseg N, Bimczok D, Kominsky DJ.

Am J Physiol Gastrointest Liver Physiol. 2019 Oct 1;317(4):G531-G544. doi: 10.1152/ajpgi.00071.2019. Epub 2019 Aug 8.

PMID:
31393789
3.

Oral vitamin B12 supplement is delivered to the distal gut, altering the corrinoid profile and selectively depleting Bacteroides in C57BL/6 mice.

Kelly CJ, Alexeev EE, Farb L, Vickery TW, Zheng L, Eric L C, Kitzenberg DA, Battista KD, Kominsky DJ, Robertson CE, Frank DN, Stabler SP, Colgan SP.

Gut Microbes. 2019;10(6):654-662. doi: 10.1080/19490976.2019.1597667. Epub 2019 May 7.

PMID:
31062653
4.

Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor.

Alexeev EE, Lanis JM, Kao DJ, Campbell EL, Kelly CJ, Battista KD, Gerich ME, Jenkins BR, Walk ST, Kominsky DJ, Colgan SP.

Am J Pathol. 2018 May;188(5):1183-1194. doi: 10.1016/j.ajpath.2018.01.011. Epub 2018 Feb 16.

5.

Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor-Dependent Repression of Claudin-2.

Zheng L, Kelly CJ, Battista KD, Schaefer R, Lanis JM, Alexeev EE, Wang RX, Onyiah JC, Kominsky DJ, Colgan SP.

J Immunol. 2017 Oct 15;199(8):2976-2984. doi: 10.4049/jimmunol.1700105. Epub 2017 Sep 11.

6.

Intestinal Epithelial Ecto-5'-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella.

Kao DJ, Saeedi BJ, Kitzenberg D, Burney KM, Dobrinskikh E, Battista KD, Vázquez-Torres A, Colgan SP, Kominsky DJ.

Infect Immun. 2017 Sep 20;85(10). pii: e01022-16. doi: 10.1128/IAI.01022-16. Print 2017 Oct.

7.

4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists.

Kirpotina LN, Schepetkin IA, Khlebnikov AI, Ruban OI, Ge Y, Ye RD, Kominsky DJ, Quinn MT.

Biochem Pharmacol. 2017 Oct 15;142:120-132. doi: 10.1016/j.bcp.2017.07.004. Epub 2017 Jul 8.

8.

Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia.

Lanis JM, Alexeev EE, Curtis VF, Kitzenberg DA, Kao DJ, Battista KD, Gerich ME, Glover LE, Kominsky DJ, Colgan SP.

Mucosal Immunol. 2017 Sep;10(5):1133-1144. doi: 10.1038/mi.2016.133. Epub 2017 Jan 18.

9.

Perturbation of neddylation-dependent NF-κB responses in the intestinal epithelium drives apoptosis and inhibits resolution of mucosal inflammation.

Ehrentraut SF, Curtis VF, Wang RX, Saeedi BJ, Ehrentraut H, Onyiah JC, Kelly CJ, Campbell EL, Glover LE, Kominsky DJ, Colgan SP.

Mol Biol Cell. 2016 Sep 28. pii: mbc.E16-05-0273. [Epub ahead of print]

10.

NMR-Based Metabolomic Analysis of Normal and Inflamed Gut.

Kao DJ, Lanis JM, Alexeev E, Kominsky DJ.

Methods Mol Biol. 2016;1422:77-87. doi: 10.1007/978-1-4939-3603-8_8.

PMID:
27246024
11.

HPLC-Based Metabolomic Analysis of Normal and Inflamed Gut.

Kao DJ, Lanis JM, Alexeev E, Kominsky DJ.

Methods Mol Biol. 2016;1422:63-75. doi: 10.1007/978-1-4939-3603-8_7.

PMID:
27246023
12.

Hypoxia and Mucosal Inflammation.

Colgan SP, Campbell EL, Kominsky DJ.

Annu Rev Pathol. 2016 May 23;11:77-100. doi: 10.1146/annurev-pathol-012615-044231. Review.

13.

HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity.

Saeedi BJ, Kao DJ, Kitzenberg DA, Dobrinskikh E, Schwisow KD, Masterson JC, Kendrick AA, Kelly CJ, Bayless AJ, Kominsky DJ, Campbell EL, Kuhn KA, Furuta GT, Colgan SP, Glover LE.

Mol Biol Cell. 2015 Jun 15;26(12):2252-62. doi: 10.1091/mbc.E14-07-1194. Epub 2015 Apr 22.

14.

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function.

Kelly CJ, Zheng L, Campbell EL, Saeedi B, Scholz CC, Bayless AJ, Wilson KE, Glover LE, Kominsky DJ, Magnuson A, Weir TL, Ehrentraut SF, Pickel C, Kuhn KA, Lanis JM, Nguyen V, Taylor CT, Colgan SP.

Cell Host Microbe. 2015 May 13;17(5):662-71. doi: 10.1016/j.chom.2015.03.005. Epub 2015 Apr 9.

15.

Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses.

Curtis VF, Ehrentraut SF, Campbell EL, Glover LE, Bayless A, Kelly CJ, Kominsky DJ, Colgan SP.

FASEB J. 2015 Jan;29(1):208-15. doi: 10.1096/fj.14-259663. Epub 2014 Oct 17.

16.

Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation.

Campbell EL, Bruyninckx WJ, Kelly CJ, Glover LE, McNamee EN, Bowers BE, Bayless AJ, Scully M, Saeedi BJ, Golden-Mason L, Ehrentraut SF, Curtis VF, Burgess A, Garvey JF, Sorensen A, Nemenoff R, Jedlicka P, Taylor CT, Kominsky DJ, Colgan SP.

Immunity. 2014 Jan 16;40(1):66-77. doi: 10.1016/j.immuni.2013.11.020. Epub 2014 Jan 9.

17.

IFN-γ-mediated induction of an apical IL-10 receptor on polarized intestinal epithelia.

Kominsky DJ, Campbell EL, Ehrentraut SF, Wilson KE, Kelly CJ, Glover LE, Collins CB, Bayless AJ, Saeedi B, Dobrinskikh E, Bowers BE, MacManus CF, Müller W, Colgan SP, Bruder D.

J Immunol. 2014 Feb 1;192(3):1267-76. doi: 10.4049/jimmunol.1301757. Epub 2013 Dec 23.

18.

Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis.

Glover LE, Bowers BE, Saeedi B, Ehrentraut SF, Campbell EL, Bayless AJ, Dobrinskikh E, Kendrick AA, Kelly CJ, Burgess A, Miller L, Kominsky DJ, Jedlicka P, Colgan SP.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19820-5. doi: 10.1073/pnas.1302840110. Epub 2013 Nov 18.

19.

HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium.

Eckle T, Brodsky K, Bonney M, Packard T, Han J, Borchers CH, Mariani TJ, Kominsky DJ, Mittelbronn M, Eltzschig HK.

PLoS Biol. 2013 Sep;11(9):e1001665. doi: 10.1371/journal.pbio.1001665. Epub 2013 Sep 24.

20.

Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis.

Keely S, Campbell EL, Baird AW, Hansbro PM, Shalwitz RA, Kotsakis A, McNamee EN, Eltzschig HK, Kominsky DJ, Colgan SP.

Mucosal Immunol. 2014 Jan;7(1):114-23. doi: 10.1038/mi.2013.29. Epub 2013 May 22.

21.

Fundamental role for HIF-1α in constitutive expression of human β defensin-1.

Kelly CJ, Glover LE, Campbell EL, Kominsky DJ, Ehrentraut SF, Bowers BE, Bayless AJ, Saeedi BJ, Colgan SP.

Mucosal Immunol. 2013 Nov;6(6):1110-8. doi: 10.1038/mi.2013.6. Epub 2013 Mar 6.

22.

Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response.

Ehrentraut SF, Kominsky DJ, Glover LE, Campbell EL, Kelly CJ, Bowers BE, Bayless AJ, Colgan SP.

J Immunol. 2013 Jan 1;190(1):392-400. doi: 10.4049/jimmunol.1202041. Epub 2012 Dec 3.

23.

Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury.

Martin-Murphy BV, Kominsky DJ, Orlicky DJ, Donohue TM Jr, Ju C.

Hepatology. 2013 Apr;57(4):1575-84. doi: 10.1002/hep.26134. Epub 2013 Jan 18.

24.

Contributions of neutrophils to resolution of mucosal inflammation.

Colgan SP, Ehrentraut SF, Glover LE, Kominsky DJ, Campbell EL.

Immunol Res. 2013 Mar;55(1-3):75-82. doi: 10.1007/s12026-012-8350-2. Review.

25.

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.

Eckle T, Hartmann K, Bonney S, Reithel S, Mittelbronn M, Walker LA, Lowes BD, Han J, Borchers CH, Buttrick PM, Kominsky DJ, Colgan SP, Eltzschig HK.

Nat Med. 2012 Apr 15;18(5):774-82. doi: 10.1038/nm.2728.

26.

Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease.

Goldstein JI, Kominsky DJ, Jacobson N, Bowers B, Regalia K, Austin GL, Yousefi M, Falta MT, Fontenot AP, Gerich ME, Golden-Mason L, Colgan SP.

Gastroenterology. 2011 Jul;141(1):208-16. doi: 10.1053/j.gastro.2011.03.060. Epub 2011 Apr 7.

27.

An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling.

Kominsky DJ, Keely S, MacManus CF, Glover LE, Scully M, Collins CB, Bowers BE, Campbell EL, Colgan SP.

J Immunol. 2011 Jun 1;186(11):6505-14. doi: 10.4049/jimmunol.1002805. Epub 2011 Apr 22.

28.

Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization.

MacManus CF, Campbell EL, Keely S, Burgess A, Kominsky DJ, Colgan SP.

FASEB J. 2011 Jun;25(6):1856-64. doi: 10.1096/fj.10-170316. Epub 2011 Feb 24.

29.

IFN-γ attenuates hypoxia-inducible factor (HIF) activity in intestinal epithelial cells through transcriptional repression of HIF-1β.

Glover LE, Irizarry K, Scully M, Campbell EL, Bowers BE, Aherne CM, Kominsky DJ, MacManus CF, Colgan SP.

J Immunol. 2011 Feb 1;186(3):1790-8. doi: 10.4049/jimmunol.1001442. Epub 2011 Jan 3.

30.

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification.

Campbell EL, MacManus CF, Kominsky DJ, Keely S, Glover LE, Bowers BE, Scully M, Bruyninckx WJ, Colgan SP.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14298-303. doi: 10.1073/pnas.0914730107. Epub 2010 Jul 26.

31.

Metabolic shifts in immunity and inflammation.

Kominsky DJ, Campbell EL, Colgan SP.

J Immunol. 2010 Apr 15;184(8):4062-8. doi: 10.4049/jimmunol.0903002. Review.

32.

Metabolic characteristics of imatinib resistance in chronic myeloid leukaemia cells.

Klawitter J, Kominsky DJ, Brown JL, Klawitter J, Christians U, Leibfritz D, Melo JV, Eckhardt SG, Serkova NJ.

Br J Pharmacol. 2009 Sep;158(2):588-600. doi: 10.1111/j.1476-5381.2009.00345.x. Epub 2009 Aug 6.

33.

Abnormalities in glucose uptake and metabolism in imatinib-resistant human BCR-ABL-positive cells.

Kominsky DJ, Klawitter J, Brown JL, Boros LG, Melo JV, Eckhardt SG, Serkova NJ.

Clin Cancer Res. 2009 May 15;15(10):3442-50. doi: 10.1158/1078-0432.CCR-08-3291. Epub 2009 Apr 28.

34.

Enhanced leukocyte HIF-1alpha and HIF-1 DNA binding in humans after rapid ascent to 4300 m.

Tissot van Patot MC, Serkova NJ, Haschke M, Kominsky DJ, Roach RC, Christians U, Henthorn TK, Honigman B.

Free Radic Biol Med. 2009 Jun 1;46(11):1551-7. doi: 10.1016/j.freeradbiomed.2009.03.009. Epub 2009 Mar 19.

PMID:
19303436
35.

Use of the 1-mm micro-probe for metabolic analysis on small volume biological samples.

Serkova NJ, Freund AS, Brown JL, Kominsky DJ.

J Cell Mol Med. 2009 Aug;13(8B):1933-41. doi: 10.1111/j.1582-4934.2008.00464.x.

36.

Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine.

Rudolph MC, McManaman JL, Phang T, Russell T, Kominsky DJ, Serkova NJ, Stein T, Anderson SM, Neville MC.

Physiol Genomics. 2007 Feb 12;28(3):323-36. Epub 2006 Nov 14.

37.

Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression.

Peng ZY, Serkova NJ, Kominsky DJ, Brown JL, Wischmeyer PE.

JPEN J Parenter Enteral Nutr. 2006 Sep-Oct;30(5):373-8; discussion 379.

PMID:
16931604
38.

Genetic and biochemical basis for viability of yeast lacking mitochondrial genomes.

Kominsky DJ, Brownson MP, Updike DL, Thorsness PE.

Genetics. 2002 Dec;162(4):1595-604.

39.

Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors.

Richardson-Burns SM, Kominsky DJ, Tyler KL.

J Neurovirol. 2002 Oct;8(5):365-80.

PMID:
12402163
41.

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