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Items: 1 to 50 of 218

1.

Association between metastatic sites and first-line pembrolizumab treatment outcome for advanced non-small cell lung cancer with high PD-L1 expression: a retrospective multicenter cohort study.

Kawachi H, Tamiya M, Tamiya A, Ishii S, Hirano K, Matsumoto H, Fukuda Y, Yokoyama T, Kominami R, Fujimoto D, Hosoya K, Suzuki H, Hirashima T, Kanazu M, Sawa N, Uchida J, Morita M, Makio T, Hara S, Kumagai T.

Invest New Drugs. 2019 Nov 30. doi: 10.1007/s10637-019-00882-5. [Epub ahead of print]

PMID:
31784866
2.

Efficacy and safety of pembrolizumab as first-line therapy in advanced non-small cell lung cancer with at least 50% PD-L1 positivity: a multicenter retrospective cohort study (HOPE-001).

Tamiya M, Tamiya A, Hosoya K, Taniguchi Y, Yokoyama T, Fukuda Y, Hirano K, Matsumoto H, Kominami R, Suzuki H, Hirashima T, Uchida J, Morita M, Kanazu M, Sawa N, Kinoshita Y, Hara S, Kumagai T, Fujimoto D.

Invest New Drugs. 2019 Dec;37(6):1266-1273. doi: 10.1007/s10637-019-00843-y. Epub 2019 Aug 7.

PMID:
31392549
3.

A Polymorphic Variant in p19Arf Confers Resistance to Chemically Induced Skin Tumors by Activating the p53 Pathway.

Saito M, Okumura K, Isogai E, Araki K, Tanikawa C, Matsuda K, Kamijo T, Kominami R, Wakabayashi Y.

J Invest Dermatol. 2019 Jul;139(7):1459-1469. doi: 10.1016/j.jid.2018.12.027. Epub 2019 Jan 23.

PMID:
30684556
4.

Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.

Kojo S, Tanaka H, Endo TA, Muroi S, Liu Y, Seo W, Tenno M, Kakugawa K, Naoe Y, Nair K, Moro K, Katsuragi Y, Kanai A, Inaba T, Egawa T, Venkatesh B, Minoda A, Kominami R, Taniuchi I.

Nat Commun. 2017 Sep 26;8(1):702. doi: 10.1038/s41467-017-00768-1.

5.

The parathyroid hormone regulates skin tumour susceptibility in mice.

Okumura K, Saito M, Yoshizawa Y, Munakata H, Isogai E, Miura I, Wakana S, Yamaguchi M, Shitara H, Taya C, Karaplis AC, Kominami R, Wakabayashi Y.

Sci Rep. 2017 Sep 11;7(1):11208. doi: 10.1038/s41598-017-11561-x.

6.

Design of and rationale for the Japan Diabetes compREhensive database project based on an Advanced electronic Medical record System (J-DREAMS).

Sugiyama T, Miyo K, Tsujimoto T, Kominami R, Ohtsu H, Ohsugi M, Waki K, Noguchi T, Ohe K, Kadowaki T, Kasuga M, Ueki K, Kajio H.

Diabetol Int. 2017 Jun 27;8(4):375-382. doi: 10.1007/s13340-017-0326-y. eCollection 2017 Nov.

7.

BCL11B gene heterozygosity causes weight loss accompanied by increased energy consumption, but not defective adipogenesis, in mice.

Inoue J, Ihara Y, Tsukamoto D, Yasumoto K, Hashidume T, Kamimura K, Hirano S, Shimizu M, Kominami R, Sato R.

Biosci Biotechnol Biochem. 2017 May;81(5):922-930. doi: 10.1080/09168451.2016.1274642. Epub 2017 Jan 9.

PMID:
28067590
8.

Identification of the optimal method for removing the capsule from the acinus of the rat's mandibular glands when preparing specimens for superficial morphology examination.

Uemura M, Arakawa T, Kominami R, Honma S, Takemura A.

Okajimas Folia Anat Jpn. 2017;94(3):109-113. doi: 10.2535/ofaj.94.109.

9.

Factors associated with the relapse of cryptogenic and secondary organizing pneumonia.

Onishi Y, Kawamura T, Nakahara Y, Kagami R, Sasaki S, Takahashi S, Kominami R, Hirano K, Hiraoka R, Hirata N.

Respir Investig. 2017 Jan;55(1):10-15. doi: 10.1016/j.resinv.2016.09.001. Epub 2016 Oct 25.

PMID:
28012487
10.

Identification of BCL11B as a regulator of adipogenesis.

Inoue J, Ihara Y, Tsukamoto D, Yasumoto K, Hashidume T, Kamimura K, Nakai Y, Hirano S, Shimizu M, Kominami R, Sato R.

Sci Rep. 2016 Sep 2;6:32750. doi: 10.1038/srep32750.

11.

Bcl11b/Ctip2 is required for development of lingual papillae in mice.

Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J.

Dev Biol. 2016 Aug 1;416(1):98-110. doi: 10.1016/j.ydbio.2016.06.001. Epub 2016 Jun 7.

12.

Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.

Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Yonekawa H, Kikkawa Y.

Hum Mol Genet. 2016 May 15;25(10):2045-2059. Epub 2016 Mar 2.

PMID:
26936824
13.

Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after γ-irradiation through Wnt/β-catenin pathway.

Sakamaki A, Katsuragi Y, Otsuka K, Tomita M, Obata M, Iwasaki T, Abe M, Sato T, Ochiai M, Sakuraba Y, Aoyagi Y, Gondo Y, Sakimura K, Nakagama H, Mishima Y, Kominami R.

Carcinogenesis. 2015 Jun;36(6):622-31. doi: 10.1093/carcin/bgv044. Epub 2015 Mar 31.

PMID:
25827435
14.

Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner.

Hirose S, Touma M, Go R, Katsuragi Y, Sakuraba Y, Gondo Y, Abe M, Sakimura K, Mishima Y, Kominami R.

Int Immunol. 2015 Apr;27(4):205-15. doi: 10.1093/intimm/dxu104. Epub 2014 Nov 24.

PMID:
25422283
15.

Successful management of severe intrahepatic cholestasis of pregnancy: report of a first Japanese case.

Kamimura K, Abe H, Kamimura N, Yamaguchi M, Mamizu M, Ogi K, Takahashi Y, Mizuno K, Kamimura H, Kobayashi Y, Takeuchi M, Yoshida K, Yamada K, Enomoto T, Takakuwa K, Nomoto M, Obata M, Katsuragi Y, Mishima Y, Kominami R, Kamimura T, Aoyagi Y.

BMC Gastroenterol. 2014 Sep 13;14:160. doi: 10.1186/1471-230X-14-160.

17.

Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.

Okumura K, Saito M, Isogai E, Aoto Y, Hachiya T, Sakakibara Y, Katsuragi Y, Hirose S, Kominami R, Goitsuka R, Nakamura T, Wakabayashi Y.

PLoS One. 2014 Jul 11;9(7):e102111. doi: 10.1371/journal.pone.0102111. eCollection 2014.

18.

Congenic mapping and allele-specific alteration analysis of Stmm1 locus conferring resistance to early-stage chemically induced skin papillomas.

Okumura K, Saito M, Isogai E, Miura I, Wakana S, Kominami R, Wakabayashi Y.

PLoS One. 2014 May 20;9(5):e97201. doi: 10.1371/journal.pone.0097201. eCollection 2014.

19.

IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.

Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, Yoshikai Y.

J Immunol. 2014 Mar 1;192(5):2210-8. doi: 10.4049/jimmunol.1302145. Epub 2014 Jan 31.

20.

Compound heterozygosity of the functionally null Cdh23(v-ngt) and hypomorphic Cdh23(ahl) alleles leads to early-onset progressive hearing loss in mice.

Miyasaka Y, Suzuki S, Ohshiba Y, Watanabe K, Sagara Y, Yasuda SP, Matsuoka K, Shitara H, Yonekawa H, Kominami R, Kikkawa Y.

Exp Anim. 2013;62(4):333-46.

21.

Bcl11b transcription factor plays a role in the maintenance of the ameloblast-progenitors in mouse adult maxillary incisors.

Katsuragi Y, Anraku J, Nakatomi M, Ida-Yonemochi H, Obata M, Mishima Y, Sakuraba Y, Gondo Y, Kodama Y, Nishikawa A, Takagi R, Ohshima H, Kominami R.

Mech Dev. 2013 Sep-Oct;130(9-10):482-92. doi: 10.1016/j.mod.2013.05.002. Epub 2013 May 30.

22.

Cell of origin in radiation-induced premalignant thymocytes with differentiation capability in mice conditionally losing one Bcl11b allele.

Go R, Hirose S, Katsuragi Y, Obata M, Abe M, Mishima Y, Sakimura K, Kominami R.

Cancer Sci. 2013 Aug;104(8):1009-16. doi: 10.1111/cas.12193. Epub 2013 Jun 17.

23.
25.

Lmx-1b and Wnt-7a expression in axolotl limb during development and regeneration.

Shimokawa T, Yasutaka S, Kominami R, Shinohara H.

Okajimas Folia Anat Jpn. 2013;89(4):119-24.

26.

Misexpression experiment of Tbx5 in axolotl (Ambystoma mexicanum) hindlimb blastema.

Shimokawa T, Kominami R, Yasutaka S, Shinohara H.

Okajimas Folia Anat Jpn. 2013;89(4):113-8.

27.

Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus.

Tanaka H, Naito T, Muroi S, Seo W, Chihara R, Miyamoto C, Kominami R, Taniuchi I.

EMBO J. 2013 Apr 17;32(8):1183-94. doi: 10.1038/emboj.2013.47. Epub 2013 Mar 12.

28.

Wound epithelium function in axolotl limb regeneration.

Shimokawa T, Yasutaka S, Kominami R, Shinohara H.

Okajimas Folia Anat Jpn. 2012;89(3):75-81.

29.

Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms.

Okumura K, Sato M, Saito M, Miura I, Wakana S, Mao JH, Miyasaka Y, Kominami R, Wakabayashi Y.

Carcinogenesis. 2012 Nov;33(11):2260-8. doi: 10.1093/carcin/bgs250. Epub 2012 Jul 28.

PMID:
22843548
30.

Impairment in differentiation and cell cycle of thymocytes by loss of a Bcl11b tumor suppressor allele that contributes to leukemogenesis.

Go R, Takizawa K, Hirose S, Katsuragi Y, Aoyagi Y, Mishima Y, Kominami R.

Leuk Res. 2012 Aug;36(8):1035-40. doi: 10.1016/j.leukres.2012.04.028. Epub 2012 May 27.

PMID:
22640496
31.

Role of the transcription factor Bcl11b in development and lymphomagenesis.

Kominami R.

Proc Jpn Acad Ser B Phys Biol Sci. 2012;88(3):72-87. Review.

32.

BCL11B tumor suppressor inhibits HDM2 expression in a p53-dependent manner.

Obata M, Kominami R, Mishima Y.

Cell Signal. 2012 May;24(5):1047-52. doi: 10.1016/j.cellsig.2011.12.026. Epub 2012 Jan 5.

PMID:
22245141
33.

Bcl11b heterozygosity leads to age-related hearing loss and degeneration of outer hair cells of the mouse cochlea.

Okumura H, Miyasaka Y, Morita Y, Nomura T, Mishima Y, Takahashi S, Kominami R.

Exp Anim. 2011;60(4):355-61.

34.

Bcl11b/Ctip2 controls the differentiation of vomeronasal sensory neurons in mice.

Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J.

J Neurosci. 2011 Jul 13;31(28):10159-73. doi: 10.1523/JNEUROSCI.1245-11.2011.

35.

An essential developmental checkpoint for production of the T cell lineage.

Ikawa T, Hirose S, Masuda K, Kakugawa K, Satoh R, Shibano-Satoh A, Kominami R, Katsura Y, Kawamoto H.

Science. 2010 Jul 2;329(5987):93-6. doi: 10.1126/science.1188995.

36.

Clonally expanding thymocytes having lineage capability in gamma-ray-induced mouse atrophic thymus.

Yamamoto T, Morita S, Go R, Obata M, Katsuragi Y, Fujita Y, Maeda Y, Yokoyama M, Aoyagi Y, Ichikawa H, Mishima Y, Kominami R.

Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):235-43. doi: 10.1016/j.ijrobp.2009.11.005.

PMID:
20394855
37.

Bcl11b heterozygosity promotes clonal expansion and differentiation arrest of thymocytes in gamma-irradiated mice.

Go R, Hirose S, Morita S, Yamamoto T, Katsuragi Y, Mishima Y, Kominami R.

Cancer Sci. 2010 Jun;101(6):1347-53. doi: 10.1111/j.1349-7006.2010.01546.x. Epub 2010 Mar 15.

38.

Transient exposure of neonatal mice to neuregulin-1 results in hyperdopaminergic states in adulthood: implication in neurodevelopmental hypothesis for schizophrenia.

Kato T, Abe Y, Sotoyama H, Kakita A, Kominami R, Hirokawa S, Ozaki M, Takahashi H, Nawa H.

Mol Psychiatry. 2011 Mar;16(3):307-20. doi: 10.1038/mp.2010.10. Epub 2010 Feb 9. Erratum in: Mol Psychiatry. 2013 Aug;18(8):951.

PMID:
20142818
39.

Haploinsufficiency and acquired loss of Bcl11b and H2AX induces blast crisis of chronic myelogenous leukemia in a transgenic mouse model.

Nagamachi A, Yamasaki N, Miyazaki K, Oda H, Miyazaki M, Honda Z, Kominami R, Inaba T, Honda H.

Cancer Sci. 2009 Jul;100(7):1219-26. doi: 10.1111/j.1349-7006.2009.01172.x. Epub 2009 Apr 21.

40.

Polymorphisms of DNA damage response genes in radiation-related and sporadic papillary thyroid carcinoma.

Akulevich NM, Saenko VA, Rogounovitch TI, Drozd VM, Lushnikov EF, Ivanov VK, Mitsutake N, Kominami R, Yamashita S.

Endocr Relat Cancer. 2009 Jun;16(2):491-503. doi: 10.1677/ERC-08-0336. Epub 2009 Mar 13.

PMID:
19286843
41.

Pitx1 expression in developing and regenerating axolotl limbs.

Shimokawa T, Yasutaka S, Kominami R, Tanaka S, Shinohara H.

Okajimas Folia Anat Jpn. 2008 May;85(1):5-10.

42.

Effect of Bcl11b genotypes and gamma-radiation on the development of mouse thymic lymphomas.

Yoshikai Y, Sato T, Morita S, Kohara Y, Takagi R, Mishima Y, Kominami R.

Biochem Biophys Res Commun. 2008 Aug 22;373(2):282-5. doi: 10.1016/j.bbrc.2008.06.013. Epub 2008 Jun 17.

PMID:
18558082
43.

Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress and damages.

Kamimura K, Mishima Y, Obata M, Endo T, Aoyagi Y, Kominami R.

Oncogene. 2007 Aug 30;26(40):5840-50. Epub 2007 Mar 19.

PMID:
17369851
44.

Multi-step lymphomagenesis deduced from DNA changes in thymic lymphomas and atrophic thymuses at various times after gamma-irradiation.

Ohi H, Mishima Y, Kamimura K, Maruyama M, Sasai K, Kominami R.

Oncogene. 2007 Aug 9;26(36):5280-9. Epub 2007 Feb 26.

PMID:
17325664
45.

Haploinsufficiency of Bcl11b for suppression of lymphomagenesis and thymocyte development.

Kamimura K, Ohi H, Kubota T, Okazuka K, Yoshikai Y, Wakabayashi Y, Aoyagi Y, Mishima Y, Kominami R.

Biochem Biophys Res Commun. 2007 Apr 6;355(2):538-42. Epub 2007 Feb 8.

PMID:
17306224
46.

Fine mapping of Ahl3 affecting both age-related and noise-induced hearing loss.

Morita Y, Hirokawa S, Kikkawa Y, Nomura T, Yonekawa H, Shiroishi T, Takahashi S, Kominami R.

Biochem Biophys Res Commun. 2007 Mar 30;355(1):117-21. Epub 2007 Jan 30.

PMID:
17291455
47.

Mtf-1 lymphoma-susceptibility locus affects retention of large thymocytes with high ROS levels in mice after gamma-irradiation.

Maruyama M, Yamamoto T, Kohara Y, Katsuragi Y, Mishima Y, Aoyagi Y, Kominami R.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):209-15. Epub 2007 Jan 2.

PMID:
17210131
48.

Trp53 affects the developmental anomaly of clefts of the palate in irradiated mouse embryos but not clefts of the lip with or without the palate.

Narai S, Kodama Y, Maeda Y, Yokoyama M, Takagi R, Kominami R.

Radiat Res. 2006 Dec;166(6):877-82.

PMID:
17149979
49.

Radiation carcinogenesis in mouse thymic lymphomas.

Kominami R, Niwa O.

Cancer Sci. 2006 Jul;97(7):575-81. Review.

50.

Expression of TCR alpha beta partly rescues developmental arrest and apoptosis of alpha beta T cells in Bcl11b-/- mice.

Inoue J, Kanefuji T, Okazuka K, Watanabe H, Mishima Y, Kominami R.

J Immunol. 2006 May 15;176(10):5871-9.

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