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Items: 34

1.

A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice.

Leonova KI, Shneyder J, Antoch MP, Toshkov IA, Novototskaya LR, Komarov PG, Komarova EA, Gudkov AV.

Cell Cycle. 2010 Apr 1;9(7):1434-43. Epub 2010 Apr 1.

2.

Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancer.

Narizhneva NV, Tararova ND, Ryabokon P, Shyshynova I, Prokvolit A, Komarov PG, Purmal AA, Gudkov AV, Gurova KV.

Cell Cycle. 2009 Dec 15;8(24):4155-67. Epub 2009 Dec 13.

3.

Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma.

Burkhart CA, Watt F, Murray J, Pajic M, Prokvolit A, Xue C, Flemming C, Smith J, Purmal A, Isachenko N, Komarov PG, Gurova KV, Sartorelli AC, Marshall GM, Norris MD, Gudkov AV, Haber M.

Cancer Res. 2009 Aug 15;69(16):6573-80. doi: 10.1158/0008-5472.CAN-09-1075. Epub 2009 Aug 4.

4.

Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.

Kravchenko JE, Ilyinskaya GV, Komarov PG, Agapova LS, Kochetkov DV, Strom E, Frolova EI, Kovriga I, Gudkov AV, Feinstein E, Chumakov PM.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6302-7. doi: 10.1073/pnas.0802091105. Epub 2008 Apr 18.

5.

[Transcriptional inhibition of human papilloma virus in cervical carcinoma cells reactivates functions of the tumor suppressor p53].

Kochetkov DV, Il'inskaia GV, Komarov PG, Strom E, Agapova LS, Ivanov AV, Budanov AV, Frolova EI, Chumakov PM.

Mol Biol (Mosk). 2007 May-Jun;41(3):515-23. Russian.

6.

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation.

Strom E, Sathe S, Komarov PG, Chernova OB, Pavlovska I, Shyshynova I, Bosykh DA, Burdelya LG, Macklis RM, Skaliter R, Komarova EA, Gudkov AV.

Nat Chem Biol. 2006 Sep;2(9):474-9. Epub 2006 Jul 23.

PMID:
16862141
7.

p53 is a suppressor of inflammatory response in mice.

Komarova EA, Krivokrysenko V, Wang K, Neznanov N, Chernov MV, Komarov PG, Brennan ML, Golovkina TV, Rokhlin OW, Kuprash DV, Nedospasov SA, Hazen SL, Feinstein E, Gudkov AV.

FASEB J. 2005 Jun;19(8):1030-2. Epub 2005 Apr 5.

PMID:
15811878
8.

p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.

Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K, Gudkov AV.

J Biol Chem. 2003 May 2;278(18):15465-8. Epub 2003 Mar 12.

9.

Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P-glycoprotein.

Kondratov RV, Komarov PG, Becker Y, Ewenson A, Gudkov AV.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14078-83. Epub 2001 Nov 13.

10.

p53 Involvement in the control of murine hair follicle regression.

Botchkarev VA, Komarova EA, Siebenhaar F, Botchkareva NV, Sharov AA, Komarov PG, Maurer M, Gudkov AV, Gilchrest BA.

Am J Pathol. 2001 Jun;158(6):1913-9.

11.

p53 is essential for chemotherapy-induced hair loss.

Botchkarev VA, Komarova EA, Siebenhaar F, Botchkareva NV, Komarov PG, Maurer M, Gilchrest BA, Gudkov AV.

Cancer Res. 2000 Sep 15;60(18):5002-6.

12.

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.

Komarov PG, Komarova EA, Kondratov RV, Christov-Tselkov K, Coon JS, Chernov MV, Gudkov AV.

Science. 1999 Sep 10;285(5434):1733-7.

13.

Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine.

Komarov PG, Shtil AA, Holian O, Tee L, Buckingham L, Mechetner EB, Roninson IB, Coon JS.

Oncol Res. 1998;10(4):185-92.

PMID:
9778689
14.

Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function.

Komarov PG, Shtil AA, Buckingham LE, Balasubramanian M, Piraner O, Emanuele RM, Roninson IB, Coon JS.

Int J Cancer. 1996 Oct 9;68(2):245-50.

15.

[Comparative study of lipid peroxidation indicators in the heart, liver and brain of rats with varying resistance to hypoxia].

Khachatur'ian ML, Gukasov VM, Komarov PG, Pirogova LB, Bilenko MV.

Biull Eksp Biol Med. 1996 Feb;121(2):138-43. Russian. No abstract available.

PMID:
9026114
16.

[Indicators of lipid peroxidation in organs of rats with varying resistance to hypoxia].

Khachatur'ian ML, Gukasov VM, Komarov PG, Pirogova LB, Bilenko MV.

Biull Eksp Biol Med. 1996 Jan;121(1):26-9. Russian. No abstract available.

PMID:
8679997
17.

[The effect of season on lipid peroxidation indicators in the myocardium of animals with varying resistance to hypoxia].

Khachatur'ian ML, Gukasov VM, Komarov PG, Pirogova LB, Bilenko MV.

Biull Eksp Biol Med. 1995 Jul;120(7):87-90. Russian. No abstract available.

PMID:
8527793
18.

[Changes in EEG and higher nervous activity of rats during cerebral anti-ischemic protection by acelysin].

Tel'pukhov VI, Bilenko MV, Khokhlov AV, Komarov PG.

Biull Eksp Biol Med. 1992 Mar;113(3):245-7. Russian.

PMID:
1421215
19.

[Anti-ischemic protection of the brain using water-soluble form of aspirin-acelisin].

Tel'pukhov VI, Bilenko MV, Tikhomirova AI, Komarov PG, Morganov AA.

Biull Eksp Biol Med. 1992 Feb;113(2):156-9. Russian.

PMID:
1611062
20.

[Anti-ischemic action of a 1-hydroxy-2,2,6,6-tetramethylpiperidine derivative from a series of nitroxyl bioantioxidants].

Bilenko MV, Komarov PG, Morgunov AA, Zhdanov RI.

Biull Eksp Biol Med. 1991 May;111(5):500-3. Russian.

PMID:
1878565
21.

Sterically-hindered hydroxylamines as bioactive spin labels.

Zhdanov RI, Komarov PG.

Free Radic Res Commun. 1990;9(3-6):367-77. Review.

PMID:
2167275
22.

[Disorders of cardiac contractile function in ischemic shock; the protective effect of antioxidants and liposomes made from egg phospholipids].

Bilenko MV, Morgunov AA, Churakova TD, Bulgakov VG, Komarov PG.

Biull Eksp Biol Med. 1989 Dec;108(12):660-3. Russian.

PMID:
2634433
23.

[Effect of ischemia and reperfusion of the rat brain on lipid peroxidation and the protective effect of antioxidants].

Bilenko MV, Tel'pukhov VI, Churakova TD, Komarov PG.

Biull Eksp Biol Med. 1988 Apr;105(4):394-7. Russian.

PMID:
3359013
24.

[N-hydroxytetramethylpiperidines as bioantioxidants].

Komarov PG, Taskaeva ON, Zhdanov RI.

Dokl Akad Nauk SSSR. 1987;297(3):734-7. Russian. No abstract available.

PMID:
3446465
25.

[Disordered functioning of the superoxide radical-superoxide dismutase system in rat liver ischemia].

Rashba IuE, Vartanian LS, Seregina LA, Komarov PG, Bilenko MV.

Biull Eksp Biol Med. 1986 Nov;102(11):559-61. Russian.

PMID:
3022843
26.

[Assessment of the effectiveness of the action of chemical compounds on the enzymatic peroxidation of lipids].

Komarov PG, Bilenko MV, Shvedova AA, Kagan VE.

Vopr Med Khim. 1985 Mar-Apr;31(2):40-5. Russian.

PMID:
3923714
27.

[Test systems for biomonitoring based on membrane-bound enzyme complexes. V. Mixed-function monooxygenase induction in the liver microsomes of Lake Baikal fish].

Stepanova LI, Kotelevtsev SV, Komarov PG, Novikov KN, Glazer VM.

Nauchnye Doki Vyss Shkoly Biol Nauki. 1985;(9):27-32. Russian.

PMID:
4063411
28.

[Pathogenesis and methods of prevention of ischemic shock during reperfusion of prolonged ischemicized limbs].

Bilenko MV, Churakova TD, Arkhangel'skaia SL, Komarov PG.

Vestn Akad Med Nauk SSSR. 1985;(4):24-33. Russian. No abstract available.

PMID:
4013507
29.

[Protective action of antioxidants and microsomal monooxygenase inducers in ischemic and reoxygenation damage to the liver].

Bilenko MV, Kagan VE, Velikhanova DM, Komarov PG.

Biull Eksp Biol Med. 1983 Apr;95(4):30-2. Russian.

PMID:
6831014
30.

[Interaction of spin-labelled phosphatidyl choline with Ca-dependent ATPase from sarcoplasmic reticulum].

Ritov VB, Artemova LG, Azizova OA, Komarov PG, Maksina AG.

Biokhimiia. 1982 Dec;47(12):2042-7. Russian.

PMID:
6297625
31.

[Detection of MMTV gp52 in C3H and C3Hf strain mice].

Komarova EA, Komarov PG, Kriukova IN.

Vopr Virusol. 1980 Jul-Aug;(4):461-4. Russian.

PMID:
6252698
32.

[Temperature-dependent changes in the profile of the sarcoplasmic reticulum membrane hydrophobic zones].

TarakhovskiÄ­ IuS, Galushchenko IV, Boroviagin VL, Ritov VB, Komarov PG.

Biokhimiia. 1979 May;44(5):897-902. Russian.

PMID:
156564
33.

[Integral proteins of the sarcoplasmic reticulum of rabbit and carp skeletal muscles].

Ritov VB, Mel'gunov VI, Komarov PG, Alekseeva OM, Akimova EI.

Dokl Akad Nauk SSSR. 1977 Apr 1;233(4):730-3. Russian. No abstract available.

PMID:
140043
34.

[Interaction of spin-labeled saturated and unsaturated fatty acid derivatives with biological membrane lipid and protein components].

Ritov VB, Kagan VE, Maigkova GI, Moskvin MN, Komarov PG.

Biofizika. 1976 Jul-Aug;21(4):763-5. Russian.

PMID:
188490

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