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Failure of atovaquone prophylaxis for prevention of toxoplasmosis in hematopoietic cell transplant recipients.

Chueng TA, Moroz IV, Anderson AD, Morris MI, Komanduri KV, Camargo JF.

Transpl Infect Dis. 2019 Oct 15. doi: 10.1111/tid.13198. [Epub ahead of print]


Increased overall and bacterial infections following myeloablative allogeneic HCT for patients with AML in CR1.

Ustun C, Kim S, Chen M, Beitinjaneh AM, Brown VI, Dahi PB, Daly A, Diaz MA, Freytes CO, Ganguly S, Hashmi S, Hildebrandt GC, Lazarus HM, Nishihori T, Olsson RF, Page KM, Papanicolaou G, Saad A, Seo S, William BM, Wingard JR, Wirk B, Yared JA, Perales MA, Auletta JJ, Komanduri KV, Lindemans CA, Riches ML.

Blood Adv. 2019 Sep 10;3(17):2525-2536. doi: 10.1182/bloodadvances.2019000226.


Use of Chimeric Antigen Receptor T Cell Therapy in Clinical Practice for Relapsed/Refractory Aggressive B Cell Non-Hodgkin Lymphoma: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy.

Jain T, Bar M, Kansagra AJ, Chong EA, Hashmi SK, Neelapu SS, Byrne M, Jacoby E, Lazaryan A, Jacobson CA, Ansell SM, Awan FT, Burns L, Bachanova V, Bollard CM, Carpenter PA, DiPersio JF, Hamadani M, Heslop HE, Hill JA, Komanduri KV, Kovitz CA, Lazarus HM, Serrette JM, Mohty M, Miklos D, Nagler A, Pavletic SZ, Savani BN, Schuster SJ, Kharfan-Dabaja MA, Perales MA, Lin Y.

Biol Blood Marrow Transplant. 2019 Aug 22. pii: S1083-8791(19)30529-4. doi: 10.1016/j.bbmt.2019.08.015. [Epub ahead of print] Review.


Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution.

Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, Castle JC, Buell JS, Trent JC, Wilky BA.

J Immunother Cancer. 2019 Aug 8;7(1):213. doi: 10.1186/s40425-019-0689-7.


The promise of CD4+FoxP3+ regulatory T-cell manipulation in vivo: applications for allogeneic hematopoietic stem cell transplantation.

Copsel S, Wolf D, Komanduri KV, Levy RB.

Haematologica. 2019 Jul;104(7):1309-1321. doi: 10.3324/haematol.2018.198838. Epub 2019 Jun 20. Review.


Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT).

Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill JA, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK.

Bone Marrow Transplant. 2019 May 15. doi: 10.1038/s41409-019-0451-2. [Epub ahead of print]


Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial.

Wilky BA, Trucco MM, Subhawong TK, Florou V, Park W, Kwon D, Wieder ED, Kolonias D, Rosenberg AE, Kerr DA, Sfakianaki E, Foley M, Merchan JR, Komanduri KV, Trent JC.

Lancet Oncol. 2019 Jun;20(6):837-848. doi: 10.1016/S1470-2045(19)30153-6. Epub 2019 May 8.


BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT.

Copsel SN, Lightbourn CO, Barreras H, Lohse I, Wolf D, Bader CS, Manov J, Kale BJ, Shah D, Brothers SP, Perez VL, Komanduri KV, Wahlestedt C, Levy RB.

Front Immunol. 2019 Jan 24;9:3104. doi: 10.3389/fimmu.2018.03104. eCollection 2018.


Use of maintenance therapy and incidence of recurrent Cytomegalovirus DNAemia among allogeneic hematopoietic cell transplant recipients.

Camargo JF, Anderson AD, Rosa R, Kimble E, Komanduri KV, Morris MI.

Transpl Infect Dis. 2019 Apr;21(2):e13054. doi: 10.1111/tid.13054. Epub 2019 Feb 11.


ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells.

Lee DW, Santomasso BD, Locke FL, Ghobadi A, Turtle CJ, Brudno JN, Maus MV, Park JH, Mead E, Pavletic S, Go WY, Eldjerou L, Gardner RA, Frey N, Curran KJ, Peggs K, Pasquini M, DiPersio JF, van den Brink MRM, Komanduri KV, Grupp SA, Neelapu SS.

Biol Blood Marrow Transplant. 2019 Apr;25(4):625-638. doi: 10.1016/j.bbmt.2018.12.758. Epub 2018 Dec 25. Review.


Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation.

Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill J, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK.

Biol Blood Marrow Transplant. 2019 Mar;25(3):e76-e85. doi: 10.1016/j.bbmt.2018.12.068. Epub 2018 Dec 18.


Deep functional immunophenotyping predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation.

Camargo JF, Wieder ED, Kimble E, Benjamin CL, Kolonias DS, Kwon D, Chen XS, Komanduri KV.

Blood. 2019 Feb 21;133(8):867-877. doi: 10.1182/blood-2018-10-878918. Epub 2018 Dec 20.


Divining T-cell targets for cancer immunotherapy.

Komanduri KV.

Blood. 2018 Nov 1;132(18):1861-1863. doi: 10.1182/blood-2018-09-873588. No abstract available.


Superior immune reconstitution using Treg-expanded donor cells versus PTCy treatment in preclinical HSCT models.

Wolf D, Bader CS, Barreras H, Copsel S, Pfeiffer BJ, Lightbourn CO, Altman NH, Komanduri KV, Levy RB.

JCI Insight. 2018 Oct 18;3(20). pii: 121717. doi: 10.1172/jci.insight.121717.


Vaccinating donors for hematopoietic cell transplantation: A systematic review and future perspectives.

Muhsen IN, Aljurf M, Wingard JR, Poland GA, Komanduri KV, Whitaker JA, Hashmi SK.

Vaccine. 2018 Oct 1;36(41):6043-6052. doi: 10.1016/j.vaccine.2018.08.044. Epub 2018 Sep 6. Review.


Current status and future clinical directions in the prevention and treatment of relapse following hematopoietic transplantation for acute myeloid and lymphoblastic leukemia.

Craddock C, Hoelzer D, Komanduri KV.

Bone Marrow Transplant. 2019 Jan;54(1):6-16. doi: 10.1038/s41409-018-0203-8. Epub 2018 May 31.


Very Low Numbers of CD4+ FoxP3+ Tregs Expanded in Donors via TL1A-Ig and Low-Dose IL-2 Exhibit a Distinct Activation/Functional Profile and Suppress GVHD in a Preclinical Model.

Copsel S, Wolf D, Kale B, Barreras H, Lightbourn CO, Bader CS, Alperstein W, Altman NH, Komanduri KV, Levy RB.

Biol Blood Marrow Transplant. 2018 Sep;24(9):1788-1794. doi: 10.1016/j.bbmt.2018.04.026. Epub 2018 May 8.


ASBMT Practice Guidelines Committee Survey on Long-Term Follow-Up Clinics for Hematopoietic Cell Transplant Survivors.

Hashmi SK, Lee SJ, Savani BN, Burns L, Wingard JR, Perales MA, Palmer J, Chow E, Meyer E, Marks D, Mohty M, Inamoto Y, Rodriguez C, Nagler A, Sauter C, Komanduri KV, Pidala J, Hamadani M, Johnston L, Shah N, Shaughnessy P, Hamilton BK, Majhail N, Kharfan-Dabaja MA, Schriber J, DeFilipp Z, Tarlock KG, Fanning S, Curtin P, Rizzo JD, Carpenter PA.

Biol Blood Marrow Transplant. 2018 Jun;24(6):1119-1124. doi: 10.1016/j.bbmt.2018.03.023. Epub 2018 Mar 30.


Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.

Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Timmerman JM, Stiff PJ, Friedberg JW, Flinn IW, Goy A, Hill BT, Smith MR, Deol A, Farooq U, McSweeney P, Munoz J, Avivi I, Castro JE, Westin JR, Chavez JC, Ghobadi A, Komanduri KV, Levy R, Jacobsen ED, Witzig TE, Reagan P, Bot A, Rossi J, Navale L, Jiang Y, Aycock J, Elias M, Chang D, Wiezorek J, Go WY.

N Engl J Med. 2017 Dec 28;377(26):2531-2544. doi: 10.1056/NEJMoa1707447. Epub 2017 Dec 10.


Impact of Cytomegalovirus Viral Load on Probability of Spontaneous Clearance and Response to Preemptive Therapy in Allogeneic Stem Cell Transplantation Recipients.

Camargo JF, Kimble E, Rosa R, Shimose LA, Bueno MX, Jeyakumar N, Morris MI, Abbo LM, Simkins J, Alencar MC, Benjamin C, Wieder E, Jimenez A, Beitinjaneh A, Goodman M, Byrnes JJ, Lekakis LJ, Pereira D, Komanduri KV.

Biol Blood Marrow Transplant. 2018 Apr;24(4):806-814. doi: 10.1016/j.bbmt.2017.11.038. Epub 2017 Dec 5.


Payment and Care for Hematopoietic Cell Transplantation Patients: Toward a Specialized Medical Home for Complex Care Patients.

Gajewski JL, McClellan MB, Majhail NS, Hari PN, Bredeson CN, Maziarz RT, LeMaistre CF, Lill MC, Farnia SH, Komanduri KV, Boo MJ.

Biol Blood Marrow Transplant. 2018 Jan;24(1):4-12. doi: 10.1016/j.bbmt.2017.09.012. Epub 2017 Sep 28.


Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.

Neelapu SS, Tummala S, Kebriaei P, Wierda W, Gutierrez C, Locke FL, Komanduri KV, Lin Y, Jain N, Daver N, Westin J, Gulbis AM, Loghin ME, de Groot JF, Adkins S, Davis SE, Rezvani K, Hwu P, Shpall EJ.

Nat Rev Clin Oncol. 2018 Jan;15(1):47-62. doi: 10.1038/nrclinonc.2017.148. Epub 2017 Sep 19. Review.


Innately interesting interactions.

Komanduri KV.

Blood. 2017 Aug 17;130(7):844-845. doi: 10.1182/blood-2017-06-791848. No abstract available.


Emerging concepts in cytomegalovirus infection following hematopoietic stem cell transplantation.

Camargo JF, Komanduri KV.

Hematol Oncol Stem Cell Ther. 2017 Dec;10(4):233-238. doi: 10.1016/j.hemonc.2017.05.001. Epub 2017 Jun 14. Review.


Marked in Vivo Donor Regulatory T Cell Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic Stem Cell Transplantation.

Wolf D, Barreras H, Bader CS, Copsel S, Lightbourn CO, Pfeiffer BJ, Altman NH, Podack ER, Komanduri KV, Levy RB.

Biol Blood Marrow Transplant. 2017 May;23(5):757-766. doi: 10.1016/j.bbmt.2017.02.013. Epub 2017 Feb 20.


Syndrome of Inappropriate Anti-Diuretic Hormone Secretion Secondary to Strongyloides stercoralis Infection in an Allogeneic Stem Cell Transplant Patient: A Case Report and Literature Review.

Khushman M, Morris MI, Diaz L, Goodman M, Pereira D, Fuller K, Garcia-Buitrago M, Moshiree B, Zelaya S, Nayer A, Benjamin CL, Komanduri KV.

Transplant Proc. 2017 Mar;49(2):373-377. doi: 10.1016/j.transproceed.2016.12.012. Review.


National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Immune Dysregulation and Pathobiology Working Group Report.

Gea-Banacloche J, Komanduri KV, Carpenter P, Paczesny S, Sarantopoulos S, Young JA, El Kassar N, Le RQ, Schultz KR, Griffith LM, Savani BN, Wingard JR.

Biol Blood Marrow Transplant. 2017 Jun;23(6):870-881. doi: 10.1016/j.bbmt.2016.10.001. Epub 2016 Oct 14. Review.


PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies.

Qazilbash MH, Wieder E, Thall PF, Wang X, Rios R, Lu S, Kanodia S, Ruisaard KE, Giralt SA, Estey EH, Cortes J, Komanduri KV, Clise-Dwyer K, Alatrash G, Ma Q, Champlin RE, Molldrem JJ.

Leukemia. 2017 Mar;31(3):697-704. doi: 10.1038/leu.2016.254. Epub 2016 Sep 22.


Decreases in thymopoiesis of astronauts returning from space flight.

Benjamin CL, Stowe RP, St John L, Sams CF, Mehta SK, Crucian BE, Pierson DL, Komanduri KV.

JCI Insight. 2016 Aug 4;1(12):e88787. doi: 10.1172/jci.insight.88787.


The MEK inhibitor trametinib separates murine graft-versus-host disease from graft-versus-tumor effects.

Itamura H, Shindo T, Tawara I, Kubota Y, Kariya R, Okada S, Komanduri KV, Kimura S.

JCI Insight. 2016 Jul 7;1(10):e86331. doi: 10.1172/jci.insight.86331.


The use of brincidofovir for the treatment of mixed dsDNA viral infection.

Camargo JF, Morris MI, Abbo LM, Simkins J, Saneeymehri S, Alencar MC, Lekakis LJ, Komanduri KV.

J Clin Virol. 2016 Oct;83:1-4. doi: 10.1016/j.jcv.2016.07.021. Epub 2016 Aug 4.


Novel Scoring Criteria for the Evaluation of Ocular Graft-versus-Host Disease in a Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Animal Model.

Perez VL, Barsam A, Duffort S, Urbieta M, Barreras H, Lightbourn C, Komanduri KV, Levy RB.

Biol Blood Marrow Transplant. 2016 Oct;22(10):1765-1772. doi: 10.1016/j.bbmt.2016.07.012. Epub 2016 Aug 1.


Infection Rates among Acute Leukemia Patients Receiving Alternative Donor Hematopoietic Cell Transplantation.

Ballen K, Woo Ahn K, Chen M, Abdel-Azim H, Ahmed I, Aljurf M, Antin J, Bhatt AS, Boeckh M, Chen G, Dandoy C, George B, Laughlin MJ, Lazarus HM, MacMillan ML, Margolis DA, Marks DI, Norkin M, Rosenthal J, Saad A, Savani B, Schouten HC, Storek J, Szabolcs P, Ustun C, Verneris MR, Waller EK, Weisdorf DJ, Williams KM, Wingard JR, Wirk B, Wolfs T, Young JH, Auletta J, Komanduri KV, Lindemans C, Riches ML.

Biol Blood Marrow Transplant. 2016 Sep;22(9):1636-1645. doi: 10.1016/j.bbmt.2016.06.012. Epub 2016 Jun 22.


Success of an International Learning Health Care System in Hematopoietic Cell Transplantation: The American Society of Blood and Marrow Transplantation Clinical Case Forum.

Barba P, Burns LJ, Litzow MR, Juckett MB, Komanduri KV, Lee SJ, Devlin SM, Costa LJ, Khan S, King A, Klein A, Krishnan A, Malone A, Mir M, Moravec C, Selby G, Roy V, Cochran M, Stricherz MK, Westmoreland MD, Perales MA, Wood WA.

Biol Blood Marrow Transplant. 2016 Mar;22(3):564-570. doi: 10.1016/j.bbmt.2015.12.008. Epub 2015 Dec 21.


Diagnosis and Therapy of Acute Myeloid Leukemia in the Era of Molecular Risk Stratification.

Komanduri KV, Levine RL.

Annu Rev Med. 2016;67:59-72. doi: 10.1146/annurev-med-051914-021329. Epub 2015 Oct 16. Review.


A maturing understanding of naive T cells.

Komanduri KV.

Blood. 2015 Apr 30;125(18):2742-3. doi: 10.1182/blood-2015-03-633636. No abstract available.


Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants.

Herretes S, Ross DB, Duffort S, Barreras H, Yaohong T, Saeed AM, Murillo JC, Komanduri KV, Levy RB, Perez VL.

Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2348-57. doi: 10.1167/iovs.14-15630.


Selected reviews from the 2015 BMT tandem meetings.

Komanduri KV, Veys P.

Biol Blood Marrow Transplant. 2015 Feb;21(2 Suppl):S1-2. doi: 10.1016/j.bbmt.2014.12.012. Epub 2014 Dec 20. No abstract available.


Optimal benefits for hematopoietic stem cell transplantation: a consensus opinion.

Maziarz RT, Farnia S, Martin P, Komanduri KV.

Biol Blood Marrow Transplant. 2014 Nov;20(11):1671-6. doi: 10.1016/j.bbmt.2014.07.007. Epub 2014 Jul 12.


A novel reduced-intensity conditioning regimen for unrelated umbilical cord blood transplantation in children with nonmalignant diseases.

Parikh SH, Mendizabal A, Benjamin CL, Komanduri KV, Antony J, Petrovic A, Hale G, Driscoll TA, Martin PL, Page KM, Flickinger K, Moffet J, Niedzwiecki D, Kurtzberg J, Szabolcs P.

Biol Blood Marrow Transplant. 2014 Mar;20(3):326-36. doi: 10.1016/j.bbmt.2013.11.021. Epub 2013 Dec 1.


The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success.

Newman RG, Ross DB, Barreras H, Herretes S, Podack ER, Komanduri KV, Perez VL, Levy RB.

Immunol Res. 2013 Dec;57(1-3):125-39. doi: 10.1007/s12026-013-8450-7. Review.


The evolving art of hematopoietic stem cell transplantation: translational research in post-transplant immune reconstitution and immunosuppression.

Komanduri KV, Wieder ED, Benjamin CL, Levy RB.

Immunol Res. 2013 Dec;57(1-3):140-50. doi: 10.1007/s12026-013-8461-4. Review.


Targeting neovascularization in GVHD.

Komanduri KV.

Blood. 2013 Apr 25;121(17):3303-4. doi: 10.1182/blood-2013-01-480483.


MEK inhibitors selectively suppress alloreactivity and graft-versus-host disease in a memory stage-dependent manner.

Shindo T, Kim TK, Benjamin CL, Wieder ED, Levy RB, Komanduri KV.

Blood. 2013 Jun 6;121(23):4617-26. doi: 10.1182/blood-2012-12-476218. Epub 2013 Apr 10.


Pharmacists and physicians in hematopoietic stem cell transplantation: advances and opportunities to use collaborative practice agreements to improve care.

Komanduri KV.

Biol Blood Marrow Transplant. 2013 Apr;19(4):505-6. doi: 10.1016/j.bbmt.2013.02.004. Epub 2013 Feb 13. No abstract available.


GVHD protection? ThiNK iNKT cells.

Komanduri KV.

Blood. 2012 Sep 6;120(10):1972-3. doi: 10.1182/blood-2012-07-439612. No abstract available.


Vitamin D receptor upregulation in alloreactive human T cells.

Joseph RW, Bayraktar UD, Kim TK, St John LS, Popat U, Khalili J, Molldrem JJ, Wieder ED, Komanduri KV.

Hum Immunol. 2012 Jul;73(7):693-8. doi: 10.1016/j.humimm.2012.04.019. Epub 2012 Apr 28.


American Society of Blood and Marrow Transplantation Guidelines for Training in Hematopoietic Progenitor Cell Transplantation.

Khan S, Juckett MB, Komanduri KV, Krishnan A, Burns LJ; American Society of Blood and Marrow Transplantation Committee on Education.

Biol Blood Marrow Transplant. 2012 Sep;18(9):1322-8. doi: 10.1016/j.bbmt.2012.04.007. Epub 2012 Apr 19. Erratum in: Biol Blood Marrow Transplant. 2012 Oct;18(10):1614.


Simultaneous measurement of ERα, HER2, and phosphoERK1/2 in breast cancer cell lines by flow cytometry.

Bayraktar UD, Kim TK, Drews-Elger K, Benjamin C, El-Ashry D, Wieder E, Komanduri KV.

Breast Cancer Res Treat. 2011 Sep;129(2):623-8. doi: 10.1007/s10549-011-1586-z. Epub 2011 May 24.


Can Treg therapy prevent GVHD?

Komanduri KV, Champlin RE.

Blood. 2011 Jan 20;117(3):751-2. doi: 10.1182/blood-2010-11-317305. No abstract available.


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