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Items: 1 to 50 of 126

1.

RNA-seq of Isolated Chromaffin Cells Highlights the Role of Sex-Linked and Imprinted Genes in Adrenal Medulla Development.

Chan WH, Komada M, Fukushima T, Southard-Smith EM, Anderson CR, Wakefield MJ.

Sci Rep. 2019 Mar 8;9(1):3929. doi: 10.1038/s41598-019-40501-0.

2.

The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors.

Sakai R, Fukuda R, Unida S, Aki M, Ono Y, Endo A, Kusumi S, Koga D, Fukushima T, Komada M, Okiyoneda T.

J Cell Sci. 2019 Feb 7;132(3). pii: jcs228007. doi: 10.1242/jcs.228007.

PMID:
30659120
3.

IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line.

Furuta H, Yoshihara H, Fukushima T, Yoneyama Y, Ito A, Worrall C, Girnita A, Girnita L, Yoshida M, Asano T, Komada M, Kataoka N, Chida K, Hakuno F, Takahashi SI.

Oncotarget. 2018 Sep 21;9(74):33871-33883. doi: 10.18632/oncotarget.26049. eCollection 2018 Sep 21.

4.

Qualitative exploration of fear of childbirth and preferences for mode of birth among Japanese primiparas.

Takegata M, Haruna M, Morikawa M, Yonezawa K, Komada M, Severinsson E.

Nurs Health Sci. 2018 Sep;20(3):338-345. doi: 10.1111/nhs.12571.

PMID:
30311412
5.

Reorganization of Destabilized Nodes of Ranvier in βIV Spectrin Mutants Uncovers Critical Timelines for Nodal Restoration and Prevention of Motor Paresis.

Saifetiarova J, Shi Q, Paukert M, Komada M, Bhat MA.

J Neurosci. 2018 Jul 11;38(28):6267-6282. doi: 10.1523/JNEUROSCI.0515-18.2018. Epub 2018 Jun 15.

6.

Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion.

Kawaguchi K, Endo A, Fukushima T, Madoka Y, Tanaka T, Komada M.

Biochem Biophys Res Commun. 2018 May 15;499(3):635-641. doi: 10.1016/j.bbrc.2018.03.202. Epub 2018 Mar 31.

PMID:
29604273
7.

Deubiquitylases USP5 and USP13 are recruited to and regulate heat-induced stress granules through their deubiquitylating activities.

Xie X, Matsumoto S, Endo A, Fukushima T, Kawahara H, Saeki Y, Komada M.

J Cell Sci. 2018 Apr 12;131(8). pii: jcs210856. doi: 10.1242/jcs.210856.

8.

Ub-ProT reveals global length and composition of protein ubiquitylation in cells.

Tsuchiya H, Burana D, Ohtake F, Arai N, Kaiho A, Komada M, Tanaka K, Saeki Y.

Nat Commun. 2018 Feb 6;9(1):524. doi: 10.1038/s41467-018-02869-x.

9.

Bisphenol A exposure induces increased microglia and microglial related factors in the murine embryonic dorsal telencephalon and hypothalamus.

Takahashi M, Komada M, Miyazawa K, Goto S, Ikeda Y.

Toxicol Lett. 2018 Mar 1;284:113-119. doi: 10.1016/j.toxlet.2017.12.010. Epub 2017 Dec 14.

PMID:
29248573
10.

Non-Covalent Loading of Anti-Cancer Doxorubicin by Modularizable Peptide Self-Assemblies for a Nanoscale Drug Carrier.

Tomizaki KY, Kishioka K, Kataoka S, Miyatani M, Ikeda T, Komada M, Imai T, Usui K.

Molecules. 2017 Nov 6;22(11). pii: E1916. doi: 10.3390/molecules22111916.

11.

Mechanisms underlying neuro-inflammation and neurodevelopmental toxicity in the mouse neocortex following prenatal exposure to ethanol.

Komada M, Hara N, Kawachi S, Kawachi K, Kagawa N, Nagao T, Ikeda Y.

Sci Rep. 2017 Jul 10;7(1):4934. doi: 10.1038/s41598-017-04289-1.

12.

Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25.

Kawaguchi K, Uo K, Tanaka T, Komada M.

Sci Rep. 2017 Mar 22;7:45037. doi: 10.1038/srep45037.

13.

USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.

Fukushima T, Yoshihara H, Furuta H, Hakuno F, Iemura SI, Natsume T, Nakatsu Y, Kamata H, Asano T, Komada M, Takahashi SI.

Biochem Biophys Res Commun. 2017 Mar 11;484(3):522-528. doi: 10.1016/j.bbrc.2017.01.101. Epub 2017 Jan 23.

PMID:
28126338
14.

Expression of Kisspeptin in Gonadotrope Precursors in the Mouse Pituitary during Embryonic and Postnatal Development and in Adulthood.

Ikeda Y, Tagami A, Komada M, Takahashi M.

Neuroendocrinology. 2017;105(4):357-371. doi: 10.1159/000453398. Epub 2016 Nov 21.

15.

Deficiency of X-Linked Protein Kinase Nrk during Pregnancy Triggers Breast Tumor in Mice.

Yanagawa T, Denda K, Inatani T, Fukushima T, Tanaka T, Kumaki N, Inagaki Y, Komada M.

Am J Pathol. 2016 Oct;186(10):2751-60. doi: 10.1016/j.ajpath.2016.06.005. Epub 2016 Sep 12.

PMID:
27634343
16.

Prenatal exposure to di(2-ethylhexyl) phthalate impairs development of the mouse neocortex.

Komada M, Gendai Y, Kagawa N, Nagao T.

Toxicol Lett. 2016 Sep 30;259:69-79. doi: 10.1016/j.toxlet.2016.07.019. Epub 2016 Jul 27.

PMID:
27472966
17.

The Ankrd13 Family of Ubiquitin-interacting Motif-bearing Proteins Regulates Valosin-containing Protein/p97 Protein-mediated Lysosomal Trafficking of Caveolin 1.

Burana D, Yoshihara H, Tanno H, Yamamoto A, Saeki Y, Tanaka K, Komada M.

J Biol Chem. 2016 Mar 18;291(12):6218-31. doi: 10.1074/jbc.M115.710707. Epub 2016 Jan 21.

18.

Extraction of DNA from human embryos after long-term preservation in formalin and Bouin's solutions.

Nagai M, Minegishi K, Komada M, Tsuchiya M, Kameda T, Yamada S.

Congenit Anom (Kyoto). 2016 May;56(3):112-8. doi: 10.1111/cga.12148.

PMID:
26662860
19.

Filamin A interacting protein plays a role in proper positioning of callosal projection neurons in the cortex.

Yagi H, Oka Y, Komada M, Xie MJ, Noguchi K, Sato M.

Neurosci Lett. 2016 Jan 26;612:18-24. doi: 10.1016/j.neulet.2015.11.049. Epub 2015 Dec 2.

PMID:
26655467
20.

The USP8 mutational status may predict drug susceptibility in corticotroph adenomas of Cushing's disease.

Hayashi K, Inoshita N, Kawaguchi K, Ibrahim Ardisasmita A, Suzuki H, Fukuhara N, Okada M, Nishioka H, Takeuchi Y, Komada M, Takeshita A, Yamada S.

Eur J Endocrinol. 2016 Feb;174(2):213-26. doi: 10.1530/EJE-15-0689. Epub 2015 Nov 17.

PMID:
26578638
21.

Involvement of SF-1 in neurogenesis and neuronal migration in the developing neocortex.

Komada M, Takahashi M, Ikeda Y.

Neurosci Lett. 2015 Jul 23;600:85-90. doi: 10.1016/j.neulet.2015.06.005. Epub 2015 Jun 9.

PMID:
26067405
22.

Decoding the genetic basis of Cushing's disease: USP8 in the spotlight.

Theodoropoulou M, Reincke M, Fassnacht M, Komada M.

Eur J Endocrinol. 2015 Oct;173(4):M73-83. doi: 10.1530/EJE-15-0320. Epub 2015 May 26. Review.

PMID:
26012588
23.

The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.

Perez-Rivas LG, Theodoropoulou M, Ferraù F, Nusser C, Kawaguchi K, Stratakis CA, Faucz FR, Wildemberg LE, Assié G, Beschorner R, Dimopoulou C, Buchfelder M, Popovic V, Berr CM, Tóth M, Ardisasmita AI, Honegger J, Bertherat J, Gadelha MR, Beuschlein F, Stalla G, Komada M, Korbonits M, Reincke M.

J Clin Endocrinol Metab. 2015 Jul;100(7):E997-1004. doi: 10.1210/jc.2015-1453. Epub 2015 May 5.

24.

The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc.

Sun XX, He X, Yin L, Komada M, Sears RC, Dai MS.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3734-9. doi: 10.1073/pnas.1411713112. Epub 2015 Mar 9.

25.

DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation.

Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M.

J Neurosci. 2015 Feb 18;35(7):2942-58. doi: 10.1523/JNEUROSCI.5029-13.2015.

26.

Mutations in the deubiquitinase gene USP8 cause Cushing's disease.

Reincke M, Sbiera S, Hayakawa A, Theodoropoulou M, Osswald A, Beuschlein F, Meitinger T, Mizuno-Yamasaki E, Kawaguchi K, Saeki Y, Tanaka K, Wieland T, Graf E, Saeger W, Ronchi CL, Allolio B, Buchfelder M, Strom TM, Fassnacht M, Komada M.

Nat Genet. 2015 Jan;47(1):31-8. doi: 10.1038/ng.3166. Epub 2014 Dec 8.

PMID:
25485838
27.

Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation.

Yagi H, Nagano T, Xie MJ, Ikeda H, Kuroda K, Komada M, Iguchi T, Tariqur RM, Morikubo S, Noguchi K, Murase K, Okabe M, Sato M.

Sci Rep. 2014 Sep 15;4:6353. doi: 10.1038/srep06353.

28.

Newborn mice exposed prenatally to bisphenol A show hyperactivity and defective neocortical development.

Komada M, Itoh S, Kawachi K, Kagawa N, Ikeda Y, Nagao T.

Toxicology. 2014 Sep 2;323:51-60. doi: 10.1016/j.tox.2014.06.009. Epub 2014 Jun 20.

PMID:
24953688
29.

Neurobehavioral evaluation of mouse newborns exposed prenatally to low-dose bisphenol A.

Nagao T, Kawachi K, Kagawa N, Komada M.

J Toxicol Sci. 2014 Apr;39(2):231-5.

30.

Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37.

Tanno H, Shigematsu T, Nishikawa S, Hayakawa A, Denda K, Tanaka T, Komada M.

J Biol Chem. 2014 Jan 24;289(4):2415-23. doi: 10.1074/jbc.M113.528372. Epub 2013 Dec 9.

31.

ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression.

Li X, Bian Y, Takizawa Y, Hashimoto T, Ikoma T, Tanaka J, Kitamura N, Inagaki Y, Komada M, Tanaka T.

Mol Cancer Res. 2013 Nov;11(11):1437-47. doi: 10.1158/1541-7786.MCR-12-0718. Epub 2013 Oct 31.

32.

In vivo assembly of the axon initial segment in motor neurons.

Le Bras B, Fréal A, Czarnecki A, Legendre P, Bullier E, Komada M, Brophy PJ, Davenne M, Couraud F.

Brain Struct Funct. 2014 Jul;219(4):1433-50. doi: 10.1007/s00429-013-0578-7. Epub 2013 Jun 2.

33.

Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex.

Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M.

Neurosci Lett. 2013 Jun 28;547:87-91. doi: 10.1016/j.neulet.2013.05.006. Epub 2013 May 13.

PMID:
23680462
34.

The ubiquitin code and its decoding machinery in the endocytic pathway.

Tanno H, Komada M.

J Biochem. 2013 Jun;153(6):497-504. doi: 10.1093/jb/mvt028. Epub 2013 Apr 5. Review.

PMID:
23564907
35.

Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS.

Terada N, Saitoh Y, Ohno N, Komada M, Yamauchi J, Ohno S.

Histochem Cell Biol. 2013 Aug;140(2):213-22. doi: 10.1007/s00418-012-1073-6. Epub 2013 Jan 10.

PMID:
23306908
36.

Newly developed mouse newborn behavioral testing method for evaluating the risk of neurotoxicity of environmental toxicants.

Nagao T, Kagawa N, Komada M.

J Appl Toxicol. 2013 Dec;33(12):1514-9. doi: 10.1002/jat.2802. Epub 2012 Aug 10.

PMID:
22887005
37.

Balanced ubiquitination determines cellular responsiveness to extracellular stimuli.

Mukai A, Yamamoto-Hino M, Komada M, Okano H, Goto S.

Cell Mol Life Sci. 2012 Dec;69(23):4007-16. doi: 10.1007/s00018-012-1084-4. Epub 2012 Jul 24. Review.

PMID:
22825661
38.

Developmental effects of oral exposure to diethylstilbestrol on mouse placenta.

Nagao T, Kagawa N, Saito Y, Komada M.

J Appl Toxicol. 2013 Nov;33(11):1213-21. doi: 10.1002/jat.2766. Epub 2012 Jun 25.

PMID:
22733484
39.
40.

WAVE2-Abi2 complex controls growth cone activity and regulates the multipolar-bipolar transition as well as the initiation of glia-guided migration.

Xie MJ, Yagi H, Kuroda K, Wang CC, Komada M, Zhao H, Sakakibara A, Miyata T, Nagata K, Oka Y, Iguchi T, Sato M.

Cereb Cortex. 2013 Jun;23(6):1410-23. doi: 10.1093/cercor/bhs123. Epub 2012 May 22.

PMID:
22617848
41.

Maternal bisphenol A oral dosing relates to the acceleration of neurogenesis in the developing neocortex of mouse fetuses.

Komada M, Asai Y, Morii M, Matsuki M, Sato M, Nagao T.

Toxicology. 2012 May 16;295(1-3):31-8. doi: 10.1016/j.tox.2012.02.013. Epub 2012 Mar 7.

PMID:
22426297
42.

The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane.

Tanno H, Yamaguchi T, Goto E, Ishido S, Komada M.

Mol Biol Cell. 2012 Apr;23(7):1343-53. doi: 10.1091/mbc.E11-09-0817. Epub 2012 Feb 1.

43.

Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves.

Terada N, Saitoh Y, Ohno N, Komada M, Saitoh S, Peles E, Ohno S.

Mol Cell Biol. 2012 Jan;32(1):199-205. doi: 10.1128/MCB.05945-11. Epub 2011 Oct 24.

44.

Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor.

Denda K, Nakao-Wakabayashi K, Okamoto N, Kitamura N, Ryu JY, Tagawa Y, Ichisaka T, Yamanaka S, Komada M.

J Biol Chem. 2011 Aug 19;286(33):28802-10. doi: 10.1074/jbc.M111.258160. Epub 2011 Jun 29.

45.

Prenatal findings in congenital leukemia: a case report.

Sato Y, Izumi Y, Minegishi K, Komada M, Yamada S, Kakui K, Tatsumi K, Mikami Y, Fujiwara H, Konishi I.

Fetal Diagn Ther. 2011;29(4):325-30. doi: 10.1159/000323582. Epub 2011 Feb 5.

46.

Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor.

Hanafusa H, Ishikawa K, Kedashiro S, Saigo T, Iemura S, Natsume T, Komada M, Shibuya H, Nara A, Matsumoto K.

Nat Commun. 2011 Jan 18;2:158.

47.

Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif.

Abrahamsen IW, Stronen E, Wälchli S, Johansen JN, Kjellevoll S, Kumari S, Komada M, Gaudernack G, Tjonnfjord G, Toebes M, Schumacher TN, Lund-Johansen F, Olweus J.

Leukemia. 2010 Nov;24(11):1901-9. doi: 10.1038/leu.2010.186. Epub 2010 Sep 16.

PMID:
20844564
48.

Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis.

Howell OW, Rundle JL, Garg A, Komada M, Brophy PJ, Reynolds R.

J Neuropathol Exp Neurol. 2010 Oct;69(10):1017-1033. doi: 10.1097/NEN.0b013e3181f3a5b1.

49.

[Cellular functions of the deubiquitylating enzyme family].

Komada M, Endo A.

Seikagaku. 2010 May;82(5):378-87. Review. Japanese. No abstract available.

PMID:
20560428
50.

Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos.

Komada M, Fujiyama F, Yamada S, Shiota K, Nagao T.

Birth Defects Res B Dev Reprod Toxicol. 2010 Jun;89(3):213-22. doi: 10.1002/bdrb.20245.

PMID:
20549696

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