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Items: 34

1.

Small molecule antiviral β-D-N 4-hydroxycytidine inhibits a proofreading-intact coronavirus with a high genetic barrier to resistance.

Agostini ML, Pruijssers AJ, Chappell JD, Gribble J, Lu X, Andres EL, Bluemling GR, Lockwood MA, Sheahan TP, Sims AC, Natchus MG, Saindane M, Kolykhalov AA, Painter GR, Baric RS, Denison MR.

J Virol. 2019 Oct 2. pii: JVI.01348-19. doi: 10.1128/JVI.01348-19. [Epub ahead of print]

PMID:
31578288
2.

The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection.

Painter GR, Bowen RA, Bluemling GR, DeBergh J, Edpuganti V, Gruddanti PR, Guthrie DB, Hager M, Kuiper DL, Lockwood MA, Mitchell DG, Natchus MG, Sticher ZM, Kolykhalov AA.

Antiviral Res. 2019 Sep 5;171:104597. doi: 10.1016/j.antiviral.2019.104597. [Epub ahead of print]

3.

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses.

Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Luczo JM, Ganti K, Cox RM, Sticher ZM, Edpuganti V, Mitchell DG, Lockwood MA, Kolykhalov AA, Greninger AL, Moore ML, Painter GR, Lowen AC, Tompkins SM, Fearns R, Natchus MG, Plemper RK.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00766-18. doi: 10.1128/AAC.00766-18. Print 2018 Aug.

4.

Simple In Vitro Assay To Evaluate the Incorporation Efficiency of Ribonucleotide Analog 5'-Triphosphates into RNA by Human Mitochondrial DNA-Dependent RNA Polymerase.

Lu G, Bluemling GR, Mao S, Hager M, Gurale BP, Collop P, Kuiper D, Sana K, Painter GR, De La Rosa A, Kolykhalov AA.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01830-17. doi: 10.1128/AAC.01830-17. Print 2018 Feb.

5.

β-d-N 4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome.

Urakova N, Kuznetsova V, Crossman DK, Sokratian A, Guthrie DB, Kolykhalov AA, Lockwood MA, Natchus MG, Crowley MR, Painter GR, Frolova EI, Frolov I.

J Virol. 2018 Jan 17;92(3). pii: e01965-17. doi: 10.1128/JVI.01965-17. Print 2018 Feb 1.

6.

Analysis of Ribonucleotide 5'-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays.

Lu G, Bluemling GR, Collop P, Hager M, Kuiper D, Gurale BP, Painter GR, De La Rosa A, Kolykhalov AA.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01967-16. doi: 10.1128/AAC.01967-16. Print 2017 Mar.

7.

Animal Models for HCV Study.

Couto LB, Kolykhalov AA.

In: Tan SL, editor. Hepatitis C Viruses: Genomes and Molecular Biology. Norfolk (UK): Horizon Bioscience; 2006. Chapter 12.

8.

Efficient initiation of HCV RNA replication in cell culture.

Blight KJ, Kolykhalov AA, Rice CM.

Science. 2000 Dec 8;290(5498):1972-4.

9.

Molecular virology of hepatitis C virus: an update with respect to potential antiviral targets.

Blight KJ, Kolykhalov AA, Reed KE, Agapov EV, Rice CM.

Antivir Ther. 1998;3(Suppl 3):71-81. Review.

PMID:
10726057
11.

Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus.

Major ME, Mihalik K, Fernandez J, Seidman J, Kleiner D, Kolykhalov AA, Rice CM, Feinstone SM.

J Virol. 1999 Apr;73(4):3317-25.

12.

Cloning and assembly of complex libraries of full-length HCV cDNA clones.

Kolykhalov AA, Reed KE, Rice CM.

Methods Mol Med. 1999;19:289-301. doi: 10.1385/0-89603-521-2:289.

PMID:
21374370
13.

Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA.

Kolykhalov AA, Agapov EV, Blight KJ, Mihalik K, Feinstone SM, Rice CM.

Science. 1997 Jul 25;277(5325):570-4.

14.

Hepatitis C virus detection by single-round PCR specific for the terminal 3' noncoding region.

Umlauft F, Wong DT, Oefner PJ, Underhill PA, Cheung RC, Wright TL, Kolykhalov AA, Gruenewald K, Greenberg HB.

J Clin Microbiol. 1996 Oct;34(10):2552-8.

15.
16.

[Preparation and study of recombinant strains of Venezuelan equine encephalomyelitis virus expressing the PreS2-S gene of the hepatitis B virus].

Dryga SA, Sviatchenko VA, Mikriukova TP, Fursova EIu, Kiselev NN, Goncharov AM, Frolov IV, Kolykhalov AA, Agapov EV, Netesov SV.

Vopr Virusol. 1996 May-Jun;41(3):100-4. Russian.

PMID:
8928499
17.

[Study of the structure-function organization of the variola virus genome. IV. Sequencing and analysis of the nucleotide sequence of the right terminus of the India-1967 strain genome].

Blinov VM, Totmenin AV, Resenchuk SM, Olenina LV, Chizhikov VE, Kolykhalov AA, Frolov IV, Gutorov VV, Pozdniakov SG, Krasnykh VN, et al.

Mol Biol (Mosk). 1995 Jul-Aug;29(4):772-89. Russian.

PMID:
7476944
19.

[Structure-activity organization of the variola virus genome. III. Sequencing and analysis of the nucleotide sequence of the conserved region of HindIII-F, -N-, and -A-fragments of the India 1967 strain genome].

Shchelkunov SN, Resenchuk SM, Totmenin AV, Kolykhalov AA, Frolov IV, Dryga SM, Volchkov VV, Chizhikov VE, Gutorov VV, Blinov VM, et al.

Mol Biol (Mosk). 1994 Mar-Apr;28(2):392-406. Russian.

PMID:
8183271
20.

Analysis of the hemagglutination activity domains of the Venezuelan equine encephalomyelitis and eastern equine encephalomyelitis viruses.

Razumov IA, Khusainova AD, Agapov EV, Gaidamovich SYa, Pereboev AV, Kolykhalov AA, Netesov SV, Loktev VB.

Intervirology. 1994;37(6):356-60.

PMID:
8586535
21.

Localization of four antigenic sites involved in Venezuelan equine encephalomyelitis virus protection.

Agapov EV, Razumov IA, Frolov IV, Kolykhalov AA, Netesov SV, Loktev VB.

Arch Virol. 1994;139(1-2):173-81.

PMID:
7529989
22.

[Recombinant equine Venezuelan encephalomyelitis virus, expressing HBsAg].

Frolov IV, Dryga SA, Kolykhalov AA, Mikriukova TP, Agapov EV, Netesov SV.

Dokl Akad Nauk. 1993 Oct;332(6):789-91. Russian. No abstract available.

PMID:
8268812
23.

[The immunogenic properties of a recombinant vaccinia virus with an incorporated DNA copy of the 26S RNA of the Venezuelan equine encephalomyelitis virus].

Sviatchenko VA, Agapov EV, Urmanov IKh, Serpinskiĭ OI, Frolov IV, Kolykhalov AA, Ryzhikov AB, Netesov SV.

Vopr Virusol. 1993 Sep-Dec;38(5):222-6. Russian.

PMID:
8284922
24.

Nucleotide sequence analysis of variola virus HindIII M, L, I genome fragments.

Shchelkunov SN, Blinov VM, Totmenin AV, Marennikova SS, Kolykhalov AA, Frolov IV, Chizhikov VE, Gytorov VV, Gashikov PV, Belanov EF, et al.

Virus Res. 1993 Jan;27(1):25-35.

PMID:
8383392
25.

[Study of the structural-functional organization of the natural variola virus genome. I. Cloning HindIII- and XhoI-fragments of viral DNA and sequencing HindIII -M, -L, -I fragments].

Shchelkunov SN, Blinov VM, Totmenin AV, Marennikova SS, Kolykhalov AA, Frolov IV, Chizhikov VE, Gutorov VV, Gashnikov PV, Belanov EF, et al.

Mol Biol (Mosk). 1992 Sep-Oct;26(5):1099-115. Russian.

PMID:
1335120
26.

[Effect of mutations in genes of Venezuelan equine encephalomyelitis virus structural proteins on its attenuation].

Frolov IV, Agapov EV, Kolykhalov AA, Netesov SV, Sandakhchiev LS.

Dokl Akad Nauk. 1992;326(6):1078-82. Russian. No abstract available.

PMID:
1490193
27.

[Obtaining infectious Venezuelan equine encephalomyelitis virus based on a full length DNA copy of its genome].

Kolykhalov AA, Frolov IV, Agapov EV, Netesov SV, Sandakhchiev LS.

Dokl Akad Nauk. 1992;327(1):160-4. Russian. No abstract available.

PMID:
1486342
28.

[Study of the prospects for creating vector systems based on the alpha-virus genome].

Frolov IV, Kolykhalov AA, Agapov EV, Mikriukova TP, Mychka ND, Netesov SV, Sandakhchiev LS.

Dokl Akad Nauk. 1992;326(4):738-41. Russian. No abstract available.

PMID:
1486338
29.

[Marburg virus: the first determined nucleotide sequence of two genes].

Bukreev AA, Kolykhalov AA, Volchkov VE, Blinov VM, Netesov SV, Sandakhchiev LS.

Mol Gen Mikrobiol Virusol. 1991 Mar;(3):24-30. Russian.

PMID:
1857371
30.

[Comparison of the amino acid sequence of structural proteins from attenuated and pathogenic strains of the Venezuelan equine encephalomyelitis virus].

Frolov IV, Kolykhalov AA, Volchakov VE, Netesov SV, Sandakhchiev LS.

Dokl Akad Nauk SSSR. 1991;318(6):1488-91. Russian. No abstract available.

PMID:
1914828
31.

[Variants of the Venezuelan equine encephalomyelitis virus resistant to the neutralizing action of monoclonal antibodies].

Agapov EV, Lebedeva SD, Razumov IA, Frolov IV, Kolykhalov AA, Loktev VB, Netesov SV, Sandakhchiev LS.

Dokl Akad Nauk SSSR. 1991;320(6):1485-8. Russian. No abstract available.

PMID:
1804615
32.

[BsiI--a new unusual restriction endonuclease].

Degtiarev SKh, Kolykhalov AA, Rechkunova NI, Dedkov VS, Zhilkin PA.

Mol Biol (Mosk). 1990 Jan-Feb;24(1):244-7. Russian.

PMID:
2348824
33.

[A comparison of the primary structures of the 26S RNA in variants of the eastern equine encephalomyelitis virus].

Volchkov VE, Volchkova VA, Frolov IV, Kolykhalov AA, Netesov SV, Sandakhchiev LS.

Dokl Akad Nauk SSSR. 1990;313(1):216-9. Russian. No abstract available.

PMID:
2090417
34.

[Determination of substrate specificity of restriction endonuclease FauI].

Degtiarev SKh, Kolykhalov AA, Rechkunova NI, Dedkov VS.

Bioorg Khim. 1989 Jan;15(1):130-2. Russian.

PMID:
2787154

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