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Items: 1 to 50 of 114


Characteristics of motor dysfunction in longstanding HIV.

Robinson-Papp J, Gensler G, Navis A, Sherman S, Ellis RJ, Gelman BB, Kolson DL, Letendre SL, Singer EJ, Valdes-Sueiras M, Morgello S; National NeuroAIDS Tissue Consortium.

Clin Infect Dis. 2019 Oct 7. pii: ciz986. doi: 10.1093/cid/ciz986. [Epub ahead of print]


Frailty in medically complex individuals with chronic HIV.

Morgello S, Gensler G, Sherman S, Ellis RJ, Gelman BB, Kolson DL, Letendre SL, Robinson-Papp J, Rubin LH, Singer E, Valdes-Sueiras M; NNTC.

AIDS. 2019 Aug 1;33(10):1603-1611. doi: 10.1097/QAD.0000000000002250.


N2 year in review and message from the editor to our reviewers.

Dalmau J, Kolson DL, Paul F, Zamvil SS.

Neurol Neuroimmunol Neuroinflamm. 2018 Dec 19;6(1):e525. doi: 10.1212/NXI.0000000000000525. eCollection 2019 Jan. No abstract available.


Is Tobacco Use Associated with Neurocognitive Dysfunction in Individuals with HIV?

Tsima B, Ratcliffe SJ, Schnoll R, Frank I, Kolson DL, Gross R.

J Int Assoc Provid AIDS Care. 2018 Jan-Dec;17:2325958218768018. doi: 10.1177/2325958218768018.


BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism.

Stern AL, Ghura S, Gannon PJ, Akay-Espinoza C, Phan JM, Yee AC, Vassar R, Gelman BB, Kolson DL, Jordan-Sciutto KL.

J Neurosci. 2018 May 2;38(18):4288-4300. doi: 10.1523/JNEUROSCI.1280-17.2018. Epub 2018 Apr 9.


Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection.

Gill AJ, Garza R, Ambegaokar SS, Gelman BB, Kolson DL.

J Neuroinflammation. 2018 Mar 6;15(1):70. doi: 10.1186/s12974-018-1102-z.


Incidence, risk factors, and clinical implications of post-operative delirium in lung transplant recipients.

Anderson BJ, Chesley CF, Theodore M, Christie C, Tino R, Wysoczanski A, Ramphal K, Oyster M, Kalman L, Porteous MK, Bermudez CA, Cantu E, Kolson DL, Christie JD, Diamond JM.

J Heart Lung Transplant. 2018 Jun;37(6):755-762. doi: 10.1016/j.healun.2018.01.1295. Epub 2018 Feb 2.


Degradation of heme oxygenase-1 by the immunoproteasome in astrocytes: A potential interferon-γ-dependent mechanism contributing to HIV neuropathogenesis.

Kovacsics CE, Gill AJ, Ambegaokar SS, Gelman BB, Kolson DL.

Glia. 2017 Aug;65(8):1264-1277. doi: 10.1002/glia.23160. Epub 2017 May 22.


HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.

Gannon PJ, Akay-Espinoza C, Yee AC, Briand LA, Erickson MA, Gelman BB, Gao Y, Haughey NJ, Zink MC, Clements JE, Kim NS, Van De Walle G, Jensen BK, Vassar R, Pierce RC, Gill AJ, Kolson DL, Diehl JA, Mankowski JL, Jordan-Sciutto KL.

Am J Pathol. 2017 Jan;187(1):91-109. doi: 10.1016/j.ajpath.2016.09.006.


Admission plasma levels of the neuronal injury marker neuron-specific enolase are associated with mortality and delirium in sepsis.

Anderson BJ, Reilly JP, Shashaty MGS, Palakshappa JA, Wysoczanski A, Dunn TG, Kazi A, Tommasini A, Mikkelsen ME, Schweickert WD, Kolson DL, Christie JD, Meyer NJ.

J Crit Care. 2016 Dec;36:18-23. doi: 10.1016/j.jcrc.2016.06.012. Epub 2016 Jun 23.


The complement system, neuronal injury, and cognitive function in horizontally-acquired HIV-infected youth.

McGuire JL, Gill AJ, Douglas SD, Kolson DL; CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Group.

J Neurovirol. 2016 Dec;22(6):823-830. Epub 2016 Jun 6.


Central and peripheral markers of neurodegeneration and monocyte activation in HIV-associated neurocognitive disorders.

McGuire JL, Gill AJ, Douglas SD, Kolson DL; CNS HIV Anti-Retroviral Therapy Effects Research (CHARTER) group.

J Neurovirol. 2015 Aug;21(4):439-48. doi: 10.1007/s13365-015-0333-3. Epub 2015 Mar 17.


E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity.

Zyskind JW, Wang Y, Cho G, Ting JH, Kolson DL, Lynch DR, Jordan-Sciutto KL.

J Neurochem. 2015 Mar;132(6):742-55. doi: 10.1111/jnc.12956. Epub 2014 Nov 10.


Neuropathogenesis of HIV-associated neurocognitive disorders: roles for immune activation, HIV blipping and viral tropism.

Chen MF, Gill AJ, Kolson DL.

Curr Opin HIV AIDS. 2014 Nov;9(6):559-64. doi: 10.1097/COH.0000000000000105. Review.


Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders.

Gill AJ, Kovacsics CE, Cross SA, Vance PJ, Kolson LL, Jordan-Sciutto KL, Gelman BB, Kolson DL.

J Clin Invest. 2014 Oct;124(10):4459-72. doi: 10.1172/JCI72279. Epub 2014 Sep 9.


Chronic inflammation and the role for cofactors (hepatitis C, drug abuse, antiretroviral drug toxicity, aging) in HAND persistence.

Gill AJ, Kolson DL.

Curr HIV/AIDS Rep. 2014 Sep;11(3):325-35. doi: 10.1007/s11904-014-0210-3. Review.


Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium.

Al-Harthi L, Buch S, Geiger JD, Gendelman HE, He JJ, Jordan-Sciutto KL, Kolson DL, Rappaport J, Roy S, Zheng J, Fox HS.

J Neuroimmune Pharmacol. 2014 Jun;9(3):269-76. doi: 10.1007/s11481-014-9545-1. Epub 2014 May 2.


Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system.

Akay C, Cooper M, Odeleye A, Jensen BK, White MG, Vassoler F, Gannon PJ, Mankowski J, Dorsey JL, Buch AM, Cross SA, Cook DR, Peña MM, Andersen ES, Christofidou-Solomidou M, Lindl KA, Zink MC, Clements J, Pierce RC, Kolson DL, Jordan-Sciutto KL.

J Neurovirol. 2014 Feb;20(1):39-53. doi: 10.1007/s13365-013-0227-1. Epub 2014 Jan 14.


Calpain-mediated degradation of MDMx/MDM4 contributes to HIV-induced neuronal damage.

Colacurcio DJ, Yeager A, Kolson DL, Jordan-Sciutto KL, Akay C.

Mol Cell Neurosci. 2013 Nov;57:54-62. doi: 10.1016/j.mcn.2013.10.003. Epub 2013 Oct 12.


Adenosine triphosphate released from HIV-infected macrophages regulates glutamatergic tone and dendritic spine density on neurons.

Tovar-Y-Romo LB, Kolson DL, Bandaru VV, Drewes JL, Graham DR, Haughey NJ.

J Neuroimmune Pharmacol. 2013 Sep;8(4):998-1009. doi: 10.1007/s11481-013-9471-7. Epub 2013 May 18.


Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort.

Gelman BB, Lisinicchia JG, Morgello S, Masliah E, Commins D, Achim CL, Fox HS, Kolson DL, Grant I, Singer E, Yiannoutsos CT, Sherman S, Gensler G, Moore DJ, Chen T, Soukup VM.

J Acquir Immune Defic Syndr. 2013 Apr 15;62(5):487-95. doi: 10.1097/QAI.0b013e31827f1bdb.


Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.

Cross SA, Cook DR, Chi AW, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL, Kolson DL.

J Immunol. 2011 Nov 15;187(10):5015-25. doi: 10.4049/jimmunol.1101868. Epub 2011 Oct 5.


Activation status of integrated stress response pathways in neurones and astrocytes of HIV-associated neurocognitive disorders (HAND) cortex.

Akay C, Lindl KA, Shyam N, Nabet B, Goenaga-Vazquez Y, Ruzbarsky J, Wang Y, Kolson DL, Jordan-Sciutto KL.

Neuropathol Appl Neurobiol. 2012 Apr;38(2):175-200. doi: 10.1111/j.1365-2990.2011.01215.x.


NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury.

Cook DR, Gleichman AJ, Cross SA, Doshi S, Ho W, Jordan-Sciutto KL, Lynch DR, Kolson DL.

J Neurochem. 2011 Sep;118(6):1113-23. doi: 10.1111/j.1471-4159.2011.07383.x. Epub 2011 Aug 8.


Site-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity.

Akay C, Lindl KA, Wang Y, White MG, Isaacman-Beck J, Kolson DL, Jordan-Sciutto KL.

Mol Cell Neurosci. 2011 Jun;47(2):154-65. doi: 10.1016/j.mcn.2011.04.001. Epub 2011 Apr 12.


Current understanding of HIV-associated neurocognitive disorders pathogenesis.

Gannon P, Khan MZ, Kolson DL.

Curr Opin Neurol. 2011 Jun;24(3):275-83. doi: 10.1097/WCO.0b013e32834695fb. Review.


Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages.

Li J, Ye L, Cook DR, Wang X, Liu J, Kolson DL, Persidsky Y, Ho WZ.

J Neuroinflammation. 2011 Feb 15;8:15. doi: 10.1186/1742-2094-8-15.


Parallel high throughput neuronal toxicity assays demonstrate uncoupling between loss of mitochondrial membrane potential and neuronal damage in a model of HIV-induced neurodegeneration.

White MG, Wang Y, Akay C, Lindl KA, Kolson DL, Jordan-Sciutto KL.

Neurosci Res. 2011 Jun;70(2):220-9. doi: 10.1016/j.neures.2011.01.013. Epub 2011 Feb 1.


Human immunodeficiency virus-associated distal sensory polyneuropathy: still common after many successes.

Kolson DL, González-Scarano F.

Arch Neurol. 2010 May;67(5):534-5. doi: 10.1001/archneurol.2010.66. No abstract available.


Memantine for AIDS dementia complex: open-label report of ACTG 301.

Zhao Y, Navia BA, Marra CM, Singer EJ, Chang L, Berger J, Ellis RJ, Kolson DL, Simpson D, Miller EN, Lipton SA, Evans SR, Schifitto G; Adult Aids Clinical Trial Group (ACTG) 301 Team.

HIV Clin Trials. 2010 Jan-Feb;11(1):59-67. doi: 10.1310/hct1101-59.


HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities.

Lindl KA, Marks DR, Kolson DL, Jordan-Sciutto KL.

J Neuroimmune Pharmacol. 2010 Sep;5(3):294-309. doi: 10.1007/s11481-010-9205-z. Epub 2010 Apr 16. Review.


HIV and SIV induce alterations in CNS CaMKII expression and activation: a potential mechanism for cognitive impairment.

Gupta RG, Kelly KM, Helke KL, Queen SE, Karper JM, Dorsey JL, Brice AK, Adams RJ, Tarwater PM, Kolson DL, Mankowski JL.

Am J Pathol. 2010 Jun;176(6):2776-84. doi: 10.2353/ajpath.2010.090809. Epub 2010 Apr 9.


Propionibacterium acnes brain abscess appearing 10 years after neurosurgery.

Kranick SM, Vinnard C, Kolson DL.

Arch Neurol. 2009 Jun;66(6):793-5. doi: 10.1001/archneurol.2009.75.


Combination antiretroviral therapy modulates the blood oxygen level-dependent amplitude in human immunodeficiency virus-seropositive patients.

Ances BM, Roc AC, Korczykowski M, Wolf RL, Kolson DL.

J Neurovirol. 2008 Oct;14(5):418-24. doi: 10.1080/13550280802298112.


Expression and regulation of antiviral protein APOBEC3G in human neuronal cells.

Wang YJ, Wang X, Zhang H, Zhou L, Liu S, Kolson DL, Song L, Ye L, Ho WZ.

J Neuroimmunol. 2009 Jan 3;206(1-2):14-21. doi: 10.1016/j.jneuroim.2008.10.003. Epub 2008 Nov 21.


YKL-40: a candidate biomarker for simian immunodeficiency virus and human immunodeficiency virus encephalitis?

Kolson DL.

Am J Pathol. 2008 Jul;173(1):25-9. doi: 10.2353/ajpath.2008.080389. Review. No abstract available.


Frontal encephalocele in a middle-aged woman with first seizure: smells like a seizure to me.

Morley JF, Kolson DL.

Neurology. 2008 Jan 8;70(2):157. doi: 10.1212/01.wnl.0000296822.59839.38. No abstract available.


Activation of cyclin-dependent kinase 5 by calpains contributes to human immunodeficiency virus-induced neurotoxicity.

Wang Y, White MG, Akay C, Chodroff RA, Robinson J, Lindl KA, Dichter MA, Qian Y, Mao Z, Kolson DL, Jordan-Sciutto KL.

J Neurochem. 2007 Oct;103(2):439-55.


Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury.

O'Donnell LA, Agrawal A, Sabnekar P, Dichter MA, Lynch DR, Kolson DL.

J Neurochem. 2007 Sep;102(6):1905-1917. doi: 10.1111/j.1471-4159.2007.04645.x.


Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study.

Schifitto G, Navia BA, Yiannoutsos CT, Marra CM, Chang L, Ernst T, Jarvik JG, Miller EN, Singer EJ, Ellis RJ, Kolson DL, Simpson D, Nath A, Berger J, Shriver SL, Millar LL, Colquhoun D, Lenkinski R, Gonzalez RG, Lipton SA; Adult AIDS Clinical Trial Group (ACTG) 301; 700 Teams; HIV MRS Consortium.

AIDS. 2007 Sep 12;21(14):1877-86.


Detection of human immunodeficiency virus induced inflammation and oxidative stress in lenticular nuclei with magnetic resonance spectroscopy despite antiretroviral therapy.

Roc AC, Ances BM, Chawla S, Korczykowski M, Wolf RL, Kolson DL, Detre JA, Poptani H.

Arch Neurol. 2007 Sep;64(9):1249-57. Epub 2007 Jul 9.


Morphine upregulates functional expression of neurokinin-1 receptor in neurons.

Wan Q, Douglas SD, Wang X, Kolson DL, O'Donnell LA, Ho WZ.

J Neurosci Res. 2006 Nov 15;84(7):1588-96.


A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy.

Schifitto G, Yiannoutsos CT, Simpson DM, Marra CM, Singer EJ, Kolson DL, Nath A, Berger JR, Navia B; Adult AIDS Clinical Trials Group (ACTG) 301 tEAM.

J Neurovirol. 2006 Aug;12(4):328-31.


Caudate blood flow and volume are reduced in HIV+ neurocognitively impaired patients.

Ances BM, Roc AC, Wang J, Korczykowski M, Okawa J, Stern J, Kim J, Wolf R, Lawler K, Kolson DL, Detre JA.

Neurology. 2006 Mar 28;66(6):862-6.


Human immunodeficiency virus (HIV)-induced neurotoxicity: roles for the NMDA receptor subtypes.

O'Donnell LA, Agrawal A, Jordan-Sciutto KL, Dichter MA, Lynch DR, Kolson DL.

J Neurosci. 2006 Jan 18;26(3):981-90.


Cerebral gumma mimicking glioblastoma multiforme.

Ances BM, Danish SF, Kolson DL, Judy KD, Liebeskind DS.

Neurocrit Care. 2005;2(3):300-2.


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