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Items: 1 to 50 of 349

1.

The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration.

Patsalos A, Tzerpos P, Halasz L, Nagy G, Pap A, Giannakis N, Lyroni K, Koliaraki V, Pintye E, Dezso B, Kollias G, Spilianakis CG, Nagy L.

J Immunol. 2019 Sep 15;203(6):1532-1547. doi: 10.4049/jimmunol.1900553. Epub 2019 Aug 12.

PMID:
31405954
2.

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.

Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M.

Nat Cell Biol. 2019 Jun;21(6):731-742. doi: 10.1038/s41556-019-0324-3. Epub 2019 May 13.

PMID:
31086261
3.

An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis.

Karagianni N, Kranidioti K, Fikas N, Tsochatzidou M, Chouvardas P, Denis MC, Kollias G, Nikolaou C.

PLoS Comput Biol. 2019 May 9;15(5):e1006933. doi: 10.1371/journal.pcbi.1006933. eCollection 2019 May.

4.

RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.

Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V.

Cell Death Differ. 2019 Apr 15. doi: 10.1038/s41418-019-0330-9. [Epub ahead of print]

PMID:
30988397
5.

Genetic Restoration of Heme Oxygenase-1 Expression Protects from Type 1 Diabetes in NOD Mice.

Pogu J, Tzima S, Kollias G, Anegon I, Blancou P, Simon T.

Int J Mol Sci. 2019 Apr 3;20(7). pii: E1676. doi: 10.3390/ijms20071676.

6.

Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma.

Kerdidani D, Chouvardas P, Arjo AR, Giopanou I, Ntaliarda G, Guo YA, Tsikitis M, Kazamias G, Potaris K, Stathopoulos GT, Zakynthinos S, Kalomenidis I, Soumelis V, Kollias G, Tsoumakidou M.

Nat Commun. 2019 Mar 29;10(1):1405. doi: 10.1038/s41467-019-09370-z.

7.

Left pulmonary cusp ablation of refractory ventricular arrhythmia originating from the inaccessible summit.

Futyma P, Moroka K, Derndorfer M, Kollias G, Martinek M, Pürerfellner H.

Europace. 2019 Mar 8. pii: euz038. doi: 10.1093/europace/euz038. [Epub ahead of print] No abstract available.

PMID:
30848781
8.

Tumour Necrosis Factor-α Inhibition Improves Stroke Outcome in a Mouse Model of Rheumatoid Arthritis.

Bonetti NR, Diaz-Cañestro C, Liberale L, Crucet M, Akhmedov A, Merlini M, Reiner MF, Gobbato S, Stivala S, Kollias G, Ruschitzka F, Lüscher TF, Beer JH, Camici GG.

Sci Rep. 2019 Feb 18;9(1):2173. doi: 10.1038/s41598-019-38670-z.

9.

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis.

Koliaraki V, Chalkidi N, Henriques A, Tzaferis C, Polykratis A, Waisman A, Muller W, Hackam DJ, Pasparakis M, Kollias G.

Cell Rep. 2019 Jan 15;26(3):536-545.e4. doi: 10.1016/j.celrep.2018.12.072.

10.

Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation.

Scheibe K, Kersten C, Schmied A, Vieth M, Primbs T, Carlé B, Knieling F, Claussen J, Klimowicz AC, Zheng J, Baum P, Meyer S, Schürmann S, Friedrich O, Waldner MJ, Rath T, Wirtz S, Kollias G, Ekici AB, Atreya R, Raymond EL, Mbow ML, Neurath MF, Neufert C.

Gastroenterology. 2019 Mar;156(4):1082-1097.e11. doi: 10.1053/j.gastro.2018.11.029. Epub 2018 Nov 16.

PMID:
30452921
11.

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis.

Cambré I, Gaublomme D, Burssens A, Jacques P, Schryvers N, De Muynck A, Meuris L, Lambrecht S, Carter S, de Bleser P, Saeys Y, Van Hoorebeke L, Kollias G, Mack M, Simoens P, Lories R, Callewaert N, Schett G, Elewaut D.

Nat Commun. 2018 Nov 5;9(1):4613. doi: 10.1038/s41467-018-06933-4.

12.

Introduction to Mammalian Genome special issue: inflammation and immunity in cancer.

Behren A, Speidel D, Kollias G, Howell VM.

Mamm Genome. 2018 Dec;29(11-12):691-693. doi: 10.1007/s00335-018-9787-y. No abstract available.

PMID:
30390107
13.

In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Melagraki G, Ntougkos E, Papadopoulou D, Rinotas V, Leonis G, Douni E, Afantitis A, Kollias G.

Front Pharmacol. 2018 Jul 25;9:800. doi: 10.3389/fphar.2018.00800. eCollection 2018.

14.

Cigarette Smoke-Induced Emphysema Exhausts Early Cytotoxic CD8+ T Cell Responses against Nascent Lung Cancer Cells.

Kerdidani D, Magkouta S, Chouvardas P, Karavana V, Glynos K, Roumelioti F, Zakynthinos S, Wauters E, Janssens W, Lambrechts D, Kollias G, Tsoumakidou M.

J Immunol. 2018 Sep 1;201(5):1558-1569. doi: 10.4049/jimmunol.1700700. Epub 2018 Jul 23.

15.

HYPERKALEMIA IN TWO JAGUARS ( PANTHERA ONCA) ANESTHETIZED WITH DEXMEDETOMIDINE, KETAMINE, AND ISOFLURANE.

Romano M, Boesch JM, Peralta S, Parker C, Kollias G.

J Zoo Wildl Med. 2018 Jun;49(2):505-507. doi: 10.1638/2017-0147.1.

PMID:
29900768
16.

Current Status and Future Prospects of Small-molecule Protein-protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Melagraki G, Leonis G, Ntougkos E, Rinotas V, Papaneophytou C, Mavromoustakos T, Kontopidis G, Douni E, Kollias G, Afantitis A.

Curr Top Med Chem. 2018;18(8):661-673. doi: 10.2174/1568026618666180607084430. Review.

PMID:
29875003
17.

Mesenchymal MAPKAPK2/HSP27 drives intestinal carcinogenesis.

Henriques A, Koliaraki V, Kollias G.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5546-E5555. doi: 10.1073/pnas.1805683115. Epub 2018 May 29.

18.

Assessment of sequence dependent geometric distortion in contrast-enhanced MR images employed in stereotactic radiosurgery treatment planning.

Pappas EP, Seimenis I, Dellios D, Kollias G, Lampropoulos KI, Karaiskos P.

Phys Med Biol. 2018 Jun 25;63(13):135006. doi: 10.1088/1361-6560/aac7bf.

PMID:
29794347
19.

Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis.

Sakkou M, Chouvardas P, Ntari L, Prados A, Moreth K, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Denis MC, Karagianni N, Kollias G.

JCI Insight. 2018 Apr 5;3(7). pii: 98864. doi: 10.1172/jci.insight.98864. eCollection 2018 Apr 5.

20.

Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis.

Ntari L, Sakkou M, Chouvardas P, Mourouzis I, Prados A, Denis MC, Karagianni N, Pantos C, Kollias G.

Ann Rheum Dis. 2018 Jun;77(6):926-934. doi: 10.1136/annrheumdis-2017-212597. Epub 2018 Feb 23.

21.

The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts.

Armaka M, Ospelt C, Pasparakis M, Kollias G.

Nat Commun. 2018 Feb 12;9(1):618. doi: 10.1038/s41467-018-02935-4.

22.

Targeted deletion of RANKL in M cell inducer cells by the Col6a1-Cre driver.

Nagashima K, Sawa S, Nitta T, Prados A, Koliaraki V, Kollias G, Nakashima T, Takayanagi H.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):437-443. doi: 10.1016/j.bbrc.2017.09.004. Epub 2017 Sep 5.

PMID:
28882590
23.

Monte Carlo and experimental determination of correction factors for gamma knife perfexion small field dosimetry measurements.

Zoros E, Moutsatsos A, Pappas EP, Georgiou E, Kollias G, Karaiskos P, Pantelis E.

Phys Med Biol. 2017 Sep 5;62(18):7532-7555. doi: 10.1088/1361-6560/aa8590.

PMID:
28796643
24.

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.

Kaklamanos A, Rozman J, Roulis M, Karagianni N, Armaka M, Wu M, Brachthäuser L, Calzada-Wack J, Horsch M, Beckers J, Rathkolb B, Adler T, Neff F, Wolf E, Gailus-Durner V, Fuchs H, de Angelis MH, Kollias G.

Sci Rep. 2017 May 25;7(1):2397. doi: 10.1038/s41598-017-02581-8.

25.

Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Melagraki G, Ntougkos E, Rinotas V, Papaneophytou C, Leonis G, Mavromoustakos T, Kontopidis G, Douni E, Afantitis A, Kollias G.

PLoS Comput Biol. 2017 Apr 20;13(4):e1005372. doi: 10.1371/journal.pcbi.1005372. eCollection 2017 Apr.

26.

Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis.

Ntougkos E, Chouvardas P, Roumelioti F, Ospelt C, Frank-Bertoncelj M, Filer A, Buckley CD, Gay S, Nikolaou C, Kollias G.

Arthritis Rheumatol. 2017 Aug;69(8):1588-1600. doi: 10.1002/art.40128. Epub 2017 Jul 5.

27.

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions.

Frank-Bertoncelj M, Trenkmann M, Klein K, Karouzakis E, Rehrauer H, Bratus A, Kolling C, Armaka M, Filer A, Michel BA, Gay RE, Buckley CD, Kollias G, Gay S, Ospelt C.

Nat Commun. 2017 Mar 23;8:14852. doi: 10.1038/ncomms14852.

28.

Feasibility of catheter ablation renal denervation in "mild" resistant hypertension.

Chen S, Kiuchi MG, Acou WJ, Derndorfer M, Wang J, Li R, Kollias G, Martinek M, Kiuchi T, Pürerfellner H, Liu S.

J Clin Hypertens (Greenwich). 2017 Apr;19(4):361-368. doi: 10.1111/jch.12988. Epub 2017 Mar 7.

29.

Mesenchymal Cells in Colon Cancer.

Koliaraki V, Pallangyo CK, Greten FR, Kollias G.

Gastroenterology. 2017 Apr;152(5):964-979. doi: 10.1053/j.gastro.2016.11.049. Epub 2017 Jan 20. Review.

PMID:
28111227
30.

Targeted Metabolic Profiling of the Tg197 Mouse Model Reveals Itaconic Acid as a Marker of Rheumatoid Arthritis.

Michopoulos F, Karagianni N, Whalley NM, Firth MA, Nikolaou C, Wilson ID, Critchlow SE, Kollias G, Theodoridis GA.

J Proteome Res. 2016 Dec 2;15(12):4579-4590. Epub 2016 Oct 28.

31.

Utility of two modified-live virus canine distemper vaccines in wild-caught fishers (Martes pennanti).

Peper ST, Peper RL, Mitcheltree DH, Kollias GV, Brooks RP, Stevens SS, Serfass TL.

Vet Q. 2016 Dec;36(4):197-202. Epub 2015 Nov 26.

PMID:
26610027
32.

Searching for Novel Janus Kinase-2 Inhibitors Using a Combination of Pharmacophore Modeling, 3D-QSAR Studies and Virtual Screening.

Vrontaki E, Melagraki G, Afantitis A, Mavromoustakos T, Kollias G.

Mini Rev Med Chem. 2017;17(3):268-294. Review.

PMID:
27659251
33.

CollagenVI-Cre mice: A new tool to target stromal cells in secondary lymphoid organs.

Prados A, Kollias G, Koliaraki V.

Sci Rep. 2016 Sep 8;6:33027. doi: 10.1038/srep33027.

34.

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.

Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR.

Ann Rheum Dis. 2017 Mar;76(3):612-619. doi: 10.1136/annrheumdis-2016-209424. Epub 2016 Sep 5.

35.

Inferring active regulatory networks from gene expression data using a combination of prior knowledge and enrichment analysis.

Chouvardas P, Kollias G, Nikolaou C.

BMC Bioinformatics. 2016 Jun 6;17 Suppl 5:181. doi: 10.1186/s12859-016-1040-7.

36.

Opposing role of tumor necrosis factor receptor 1 signaling in T cell-mediated hepatitis and bacterial infection in mice.

Wroblewski R, Armaka M, Kondylis V, Pasparakis M, Walczak H, Mittrücker HW, Schramm C, Lohse AW, Kollias G, Ehlken H.

Hepatology. 2016 Aug;64(2):508-21. doi: 10.1002/hep.28551. Epub 2016 Apr 18.

PMID:
26991125
37.

Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection.

Segueni N, Benmerzoug S, Rose S, Gauthier A, Bourigault ML, Reverchon F, Philippeau A, Erard F, Le Bert M, Bouscayrol H, Wachter T, Garcia I, Kollias G, Jacobs M, Ryffel B, Quesniaux VF.

Sci Rep. 2016 Mar 2;6:22454. doi: 10.1038/srep22454.

38.

Transmembrane TNF-α Reverse Signaling Inhibits Lipopolysaccharide-Induced Proinflammatory Cytokine Formation in Macrophages by Inducing TGF-β: Therapeutic Implications.

Pallai A, Kiss B, Vereb G, Armaka M, Kollias G, Szekanecz Z, Szondy Z.

J Immunol. 2016 Feb 1;196(3):1146-57. doi: 10.4049/jimmunol.1501573. Epub 2016 Jan 4.

39.

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling.

Habbas S, Santello M, Becker D, Stubbe H, Zappia G, Liaudet N, Klaus FR, Kollias G, Fontana A, Pryce CR, Suter T, Volterra A.

Cell. 2015 Dec 17;163(7):1730-41. doi: 10.1016/j.cell.2015.11.023. Epub 2015 Dec 10.

40.

IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer.

Koliaraki V, Pasparakis M, Kollias G.

J Exp Med. 2015 Dec 14;212(13):2235-51. doi: 10.1084/jem.20150542. Epub 2015 Nov 30.

41.

A 'rule of 3' to revive Greek science, research and innovation.

Kollias G, Lambris JD.

Nat Immunol. 2015 Dec;16(12):1206-8. doi: 10.1038/ni.3322. No abstract available.

PMID:
26580499
42.

Low Titers of Canine Distemper Virus Antibody in Wild Fishers (Martes pennanti) in the Eastern USA.

Peper ST, Peper RL, Mitcheltree DH, Kollias GV, Brooks RP, Stevens SS, Serfass TL.

J Wildl Dis. 2016 Jan;52(1):150-3. doi: 10.7589/2015-05-108. Epub 2015 Nov 10.

PMID:
26555109
43.

Host and microbiota interactions are critical for development of murine Crohn's-like ileitis.

Roulis M, Bongers G, Armaka M, Salviano T, He Z, Singh A, Seidler U, Becker C, Demengeot J, Furtado GC, Lira SA, Kollias G.

Mucosal Immunol. 2016 May;9(3):787-97. doi: 10.1038/mi.2015.102. Epub 2015 Oct 21.

44.

Inflammation-induced formation of fat-associated lymphoid clusters.

Bénézech C, Luu NT, Walker JA, Kruglov AA, Loo Y, Nakamura K, Zhang Y, Nayar S, Jones LH, Flores-Langarica A, McIntosh A, Marshall J, Barone F, Besra G, Miles K, Allen JE, Gray M, Kollias G, Cunningham AF, Withers DR, Toellner KM, Jones ND, Veldhoen M, Nedospasov SA, McKenzie ANJ, Caamaño JH.

Nat Immunol. 2015 Aug;16(8):819-828. doi: 10.1038/ni.3215. Epub 2015 Jun 29.

45.

RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation.

Danks L, Komatsu N, Guerrini MM, Sawa S, Armaka M, Kollias G, Nakashima T, Takayanagi H.

Ann Rheum Dis. 2016 Jun;75(6):1187-95. doi: 10.1136/annrheumdis-2014-207137. Epub 2015 May 29.

PMID:
26025971
46.

Erratum to: Salvage of failed hip osteosynthesis for fractures with modular hip prosthesis.

Karampinas P, Kollias G, Vlamis J, Papadelis EA, Pneumaticos SG.

Eur J Orthop Surg Traumatol. 2015 Dec;25(8):1343. doi: 10.1007/s00590-015-1636-z. No abstract available.

PMID:
25976118
47.

Salvage of failed hip osteosynthesis for fractures with modular hip prosthesis.

Karampinas PK, Kollias G, Vlamis J, Papadelis EA, Pneumaticos SG.

Eur J Orthop Surg Traumatol. 2015 Aug;25(6):1039-45. doi: 10.1007/s00590-015-1622-5. Epub 2015 Mar 10. Erratum in: Eur J Orthop Surg Traumatol. 2015 Dec;25(8):1343.

PMID:
25753088
48.

Optimizing radiofrequency ablation of paroxysmal and persistent atrial fibrillation by direct catheter force measurement-a case-matched comparison in 198 patients.

Sigmund E, Puererfellner H, Derndorfer M, Kollias G, Winter S, Aichinger J, Nesser HJ, Martinek M.

Pacing Clin Electrophysiol. 2015 Feb;38(2):201-8. doi: 10.1111/pace.12549. Epub 2014 Dec 2.

PMID:
25469738
49.

Association of left ventricular diastolic dysfunction with 24-h aortic ambulatory blood pressure: the SAFAR study.

Zhang Y, Kollias G, Argyris AA, Papaioannou TG, Tountas C, Konstantonis GD, Achimastos A, Blacher J, Safar ME, Sfikakis PP, Protogerou AD.

J Hum Hypertens. 2015 Jul;29(7):442-8. doi: 10.1038/jhh.2014.101. Epub 2014 Nov 13.

PMID:
25391758
50.

Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis.

Roulis M, Nikolaou C, Kotsaki E, Kaffe E, Karagianni N, Koliaraki V, Salpea K, Ragoussis J, Aidinis V, Martini E, Becker C, Herschman HR, Vetrano S, Danese S, Kollias G.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4658-67. doi: 10.1073/pnas.1415762111. Epub 2014 Oct 14.

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