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Items: 1 to 50 of 53

1.

Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium.

Poppenberg KE, Jiang K, Tso MK, Snyder KV, Siddiqui AH, Kolega J, Jarvis JN, Meng H, Tutino VM.

BMC Med Genomics. 2019 Oct 30;12(1):149. doi: 10.1186/s12920-019-0591-7.

2.

Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms.

Tutino VM, Poppenberg KE, Li L, Shallwani H, Jiang K, Jarvis JN, Sun Y, Snyder KV, Levy EI, Siddiqui AH, Kolega J, Meng H.

J Transl Med. 2018 Dec 28;16(1):373. doi: 10.1186/s12967-018-1749-3.

3.

9.4T Magnetic Resonance Imaging of the Mouse Circle of Willis Enables Serial Characterization of Flow-Induced Vascular Remodeling by Computational Fluid Dynamics.

Tutino VM, Rajabzadeh-Oghaz H, Chandra AR, Gutierrez LC, Schweser F, Preda M, Chien A, Vakharia K, Ionita C, Siddiqui A, Kolega J.

Curr Neurovasc Res. 2018;15(4):312-325. doi: 10.2174/1567202616666181127165943.

PMID:
30484404
4.

Circulating neutrophil transcriptome may reveal intracranial aneurysm signature.

Tutino VM, Poppenberg KE, Jiang K, Jarvis JN, Sun Y, Sonig A, Siddiqui AH, Snyder KV, Levy EI, Kolega J, Meng H.

PLoS One. 2018 Jan 17;13(1):e0191407. doi: 10.1371/journal.pone.0191407. eCollection 2018.

5.

Assessment of Vascular Geometry for Bilateral Carotid Artery Ligation to Induce Early Basilar Terminus Aneurysmal Remodeling in Rats.

Tutino VM, Liaw N, Spernyak JA, Ionita CN, Siddiqui AH, Kolega J, Meng H.

Curr Neurovasc Res. 2016;13(1):82-92.

6.

Hypertension and Estrogen Deficiency Augment Aneurysmal Remodeling in the Rabbit Circle of Willis in Response to Carotid Ligation.

Tutino VM, Mandelbaum M, Takahashi A, Pope LC, Siddiqui A, Kolega J, Meng H.

Anat Rec (Hoboken). 2015 Nov;298(11):1903-10. doi: 10.1002/ar.23205. Epub 2015 Aug 21.

7.

Endothelial nitric oxide synthase and superoxide mediate hemodynamic initiation of intracranial aneurysms.

Liaw N, Fox JM, Siddiqui AH, Meng H, Kolega J.

PLoS One. 2014 Jul 3;9(7):e101721. doi: 10.1371/journal.pone.0101721. eCollection 2014.

8.

Aneurysmal remodeling in the circle of Willis after carotid occlusion in an experimental model.

Tutino VM, Mandelbaum M, Choi H, Pope LC, Siddiqui A, Kolega J, Meng H.

J Cereb Blood Flow Metab. 2014 Mar;34(3):415-24. doi: 10.1038/jcbfm.2013.209. Epub 2013 Dec 11.

9.

A critical role for proinflammatory behavior of smooth muscle cells in hemodynamic initiation of intracranial aneurysm.

Mandelbaum M, Kolega J, Dolan JM, Siddiqui AH, Meng H.

PLoS One. 2013 Sep 2;8(9):e74357. doi: 10.1371/journal.pone.0074357. eCollection 2013.

10.

Differential gene expression by endothelial cells under positive and negative streamwise gradients of high wall shear stress.

Dolan JM, Meng H, Sim FJ, Kolega J.

Am J Physiol Cell Physiol. 2013 Oct 15;305(8):C854-66. doi: 10.1152/ajpcell.00315.2012. Epub 2013 Jul 24.

11.

Intracranial aneurysms occur more frequently at bifurcation sites that typically experience higher hemodynamic stresses.

Alfano JM, Kolega J, Natarajan SK, Xiang J, Paluch RA, Levy EI, Siddiqui AH, Meng H.

Neurosurgery. 2013 Sep;73(3):497-505. doi: 10.1227/NEU.0000000000000016. Review.

PMID:
23756745
12.

High wall shear stress and spatial gradients in vascular pathology: a review.

Dolan JM, Kolega J, Meng H.

Ann Biomed Eng. 2013 Jul;41(7):1411-27. doi: 10.1007/s10439-012-0695-0. Epub 2012 Dec 11. Review.

13.

A role for microtubules in endothelial cell protrusion in three-dimensional matrices.

Martins GG, Kolega J.

Biol Cell. 2012 May;104(5):271-86. doi: 10.1111/boc.201100088. Epub 2012 Feb 15.

PMID:
22211516
14.

Endothelial cells express a unique transcriptional profile under very high wall shear stress known to induce expansive arterial remodeling.

Dolan JM, Sim FJ, Meng H, Kolega J.

Am J Physiol Cell Physiol. 2012 Apr 15;302(8):C1109-18. doi: 10.1152/ajpcell.00369.2011. Epub 2011 Dec 14.

15.

Newtonian viscosity model could overestimate wall shear stress in intracranial aneurysm domes and underestimate rupture risk.

Xiang J, Tremmel M, Kolega J, Levy EI, Natarajan SK, Meng H.

J Neurointerv Surg. 2012 Sep;4(5):351-7. doi: 10.1136/neurintsurg-2011-010089. Epub 2011 Sep 19.

PMID:
21990529
16.

Cellular and molecular responses of the basilar terminus to hemodynamics during intracranial aneurysm initiation in a rabbit model.

Kolega J, Gao L, Mandelbaum M, Mocco J, Siddiqui AH, Natarajan SK, Meng H.

J Vasc Res. 2011;48(5):429-42. doi: 10.1159/000324840. Epub 2011 May 31.

17.

High fluid shear stress and spatial shear stress gradients affect endothelial proliferation, survival, and alignment.

Dolan JM, Meng H, Singh S, Paluch R, Kolega J.

Ann Biomed Eng. 2011 Jun;39(6):1620-31. doi: 10.1007/s10439-011-0267-8. Epub 2011 Feb 11.

18.

Progressive aneurysm development following hemodynamic insult.

Meng H, Metaxa E, Gao L, Liaw N, Natarajan SK, Swartz DD, Siddiqui AH, Kolega J, Mocco J.

J Neurosurg. 2011 Apr;114(4):1095-103. doi: 10.3171/2010.9.JNS10368. Epub 2010 Oct 15.

PMID:
20950086
19.

Characterization of critical hemodynamics contributing to aneurysmal remodeling at the basilar terminus in a rabbit model.

Metaxa E, Tremmel M, Natarajan SK, Xiang J, Paluch RA, Mandelbaum M, Siddiqui AH, Kolega J, Mocco J, Meng H.

Stroke. 2010 Aug;41(8):1774-82. doi: 10.1161/STROKEAHA.110.585992. Epub 2010 Jul 1. Erratum in: Stroke. 2012 Jul;43(7):e69.

20.

Mapping vascular response to in vivo hemodynamics: application to increased flow at the basilar terminus.

Tremmel M, Xiang J, Hoi Y, Kolega J, Siddiqui AH, Mocco J, Meng H.

Biomech Model Mechanobiol. 2010 Aug;9(4):421-34. doi: 10.1007/s10237-009-0185-y. Epub 2010 Jan 7.

PMID:
20054605
21.

Aneurysmal changes at the basilar terminus in the rabbit elastase aneurysm model.

Meng H, Natarajan SK, Gao L, Ionita C, Kolega J, Siddiqui AH, Mocco J.

AJNR Am J Neuroradiol. 2010 Mar;31(3):E35-6; author reply E37. doi: 10.3174/ajnr.A2012. Epub 2010 Jan 6. No abstract available.

22.

Molecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation.

Wang Z, Kolega J, Hoi Y, Gao L, Swartz DD, Levy EI, Mocco J, Meng H.

Neurosurgery. 2009 Jul;65(1):169-77; discussion 177-8. doi: 10.1227/01.NEU.0000343541.85713.01.

23.

The asymmetric vascular stent: efficacy in a rabbit aneurysm model.

Ionita CN, Paciorek AM, Dohatcu A, Hoffmann KR, Bednarek DR, Kolega J, Levy EI, Hopkins LN, Rudin S, Mocco JD.

Stroke. 2009 Mar;40(3):959-65. doi: 10.1161/STROKEAHA.108.524124. Epub 2009 Jan 8.

24.

Endothelial cell layer subjected to impinging flow mimicking the apex of an arterial bifurcation.

Szymanski MP, Metaxa E, Meng H, Kolega J.

Ann Biomed Eng. 2008 Oct;36(10):1681-9. doi: 10.1007/s10439-008-9540-x. Epub 2008 Jul 25.

25.

Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow.

Metaxa E, Meng H, Kaluvala SR, Szymanski MP, Paluch RA, Kolega J.

Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H736-42. doi: 10.1152/ajpheart.01156.2007. Epub 2008 Jun 13.

26.

Nascent aneurysm formation at the basilar terminus induced by hemodynamics.

Gao L, Hoi Y, Swartz DD, Kolega J, Siddiqui A, Meng H.

Stroke. 2008 Jul;39(7):2085-90. doi: 10.1161/STROKEAHA.107.509422. Epub 2008 May 1.

27.

Asymmetric vascular stent: feasibility study of a new low-porosity patch-containing stent.

Ionita CN, Paciorek AM, Hoffmann KR, Bednarek DR, Yamamoto J, Kolega J, Levy EI, Hopkins LN, Rudin S, Mocco J.

Stroke. 2008 Jul;39(7):2105-13. doi: 10.1161/STROKEAHA.107.503862. Epub 2008 Apr 24.

28.

Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation.

Meng H, Wang Z, Hoi Y, Gao L, Metaxa E, Swartz DD, Kolega J.

Stroke. 2007 Jun;38(6):1924-31. Epub 2007 May 10.

29.

A model system for mapping vascular responses to complex hemodynamics at arterial bifurcations in vivo.

Meng H, Swartz DD, Wang Z, Hoi Y, Kolega J, Metaxa EM, Szymanski MP, Yamamoto J, Sauvageau E, Levy EI.

Neurosurgery. 2006 Nov;59(5):1094-100; discussion 1100-1.

31.

Endothelial cell protrusion and migration in three-dimensional collagen matrices.

Martins GG, Kolega J.

Cell Motil Cytoskeleton. 2006 Feb;63(2):101-15.

PMID:
16395720
32.

Phototoxicity and photoinactivation of blebbistatin in UV and visible light.

Kolega J.

Biochem Biophys Res Commun. 2004 Jul 30;320(3):1020-5.

PMID:
15240150
35.
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40.

Potential of machine-vision light microscopy in toxicologic pathology.

Taylor DL, DeBiasio R, LaRocca G, Pane D, Post P, Kolega J, Giuliano K, Burton K, Gough B, Dow A, et al.

Toxicol Pathol. 1994 Mar-Apr;22(2):145-59. Review.

PMID:
7973362
42.

Myosin II phosphorylation and the dynamics of stress fibers in serum-deprived and stimulated fibroblasts.

Giuliano KA, Kolega J, DeBiasio RL, Taylor DL.

Mol Biol Cell. 1992 Sep;3(9):1037-48.

43.
44.
45.

Modulation of contraction by gelation/solation in a reconstituted motile model.

Janson LW, Kolega J, Taylor DL.

J Cell Biol. 1991 Sep;114(5):1005-15.

46.

Tissue-specific distribution of a novel component of epithelial basement membranes.

Kolega J, Manabe M.

Exp Cell Res. 1990 Aug;189(2):213-21.

PMID:
2196181
47.

Basement membrane heterogeneity and variation in corneal epithelial differentiation.

Kolega J, Manabe M, Sun TT.

Differentiation. 1989 Oct;42(1):54-63.

PMID:
2695378
49.

The cellular basis of epithelial morphogenesis.

Kolega J.

Dev Biol (N Y 1985). 1986;2:103-43. Review.

PMID:
3078113
50.

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