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Items: 29

1.

Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation.

Takimoto A, Kokubu C, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y, Shukunami C.

Sci Rep. 2019 Mar 14;9(1):4605. doi: 10.1038/s41598-019-40810-4.

2.

Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis.

Yamanishi A, Matsuba A, Kondo R, Akamatsu R, Tanaka S, Tokunaga M, Horie K, Kokubu C, Ishida Y, Takeda J.

Nucleic Acids Res. 2018 Jun 1;46(10):e63. doi: 10.1093/nar/gky183.

3.

A Pair of Maternal Chromosomes Derived from Meiotic Nondisjunction in Trisomy 21 Affects Nuclear Architecture and Transcriptional Regulation.

Omori S, Tanabe H, Banno K, Tsuji A, Nawa N, Hirata K, Kawatani K, Kokubu C, Takeda J, Taniguchi H, Arahori H, Wada K, Kitabatake Y, Ozono K.

Sci Rep. 2017 Apr 10;7(1):764. doi: 10.1038/s41598-017-00714-7.

4.

Chromatin states shape insertion profiles of the piggyBac, Tol2 and Sleeping Beauty transposons and murine leukemia virus.

Yoshida J, Akagi K, Misawa R, Kokubu C, Takeda J, Horie K.

Sci Rep. 2017 Mar 2;7:43613. doi: 10.1038/srep43613.

5.

Systematic Cellular Disease Models Reveal Synergistic Interaction of Trisomy 21 and GATA1 Mutations in Hematopoietic Abnormalities.

Banno K, Omori S, Hirata K, Nawa N, Nakagawa N, Nishimura K, Ohtaka M, Nakanishi M, Sakuma T, Yamamoto T, Toki T, Ito E, Yamamoto T, Kokubu C, Takeda J, Taniguchi H, Arahori H, Wada K, Kitabatake Y, Ozono K.

Cell Rep. 2016 May 10;15(6):1228-41. doi: 10.1016/j.celrep.2016.04.031. Epub 2016 Apr 28.

6.

Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara.

Woltjen K, Yamamoto T, Kokubu C, Takeda J.

Genes Cells. 2016 May;21(5):392-5. doi: 10.1111/gtc.12367. Epub 2016 Mar 29.

7.

COSMOS: accurate detection of somatic structural variations through asymmetric comparison between tumor and normal samples.

Yamagata K, Yamanishi A, Kokubu C, Takeda J, Sese J.

Nucleic Acids Res. 2016 May 5;44(8):e78. doi: 10.1093/nar/gkw026. Epub 2016 Feb 1.

8.

Differences in recognition of similar medication names between pharmacists and nurses: a retrospective study.

Tsuji T, Irisa T, Tagawa S, Kawashiri T, Ikesue H, Kokubu C, Kanaya A, Egashira N, Masuda S.

J Pharm Health Care Sci. 2015 Jul 7;1:19. doi: 10.1186/s40780-015-0017-4. eCollection 2015.

9.

Relationship between incident types and impact on patients in drug name errors: a correlational study.

Tsuji T, Irisa T, Ohata S, Kokubu C, Kanaya A, Sueyasu M, Egashira N, Masuda S.

J Pharm Health Care Sci. 2015 Mar 10;1:11. doi: 10.1186/s40780-015-0011-x. eCollection 2015.

10.

Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.

Tokunaga M, Kokubu C, Maeda Y, Sese J, Horie K, Sugimoto N, Kinoshita T, Yusa K, Takeda J.

BMC Genomics. 2014 Nov 24;15:1016. doi: 10.1186/1471-2164-15-1016.

11.

Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells.

Igawa K, Kokubu C, Yusa K, Horie K, Yoshimura Y, Yamauchi K, Suemori H, Yokozeki H, Toyoda M, Kiyokawa N, Okita H, Miyagawa Y, Akutsu H, Umezawa A, Katayama I, Takeda J.

Stem Cells Transl Med. 2014 Sep;3(9):992-1001. doi: 10.5966/sctm.2013-0179. Epub 2014 Jul 14.

12.

When half is better than the whole: advances in haploid embryonic stem cell technology.

Kokubu C, Takeda J.

Cell Stem Cell. 2014 Mar 6;14(3):265-7. doi: 10.1016/j.stem.2014.02.001.

13.

Pax1 acts as a negative regulator of chondrocyte maturation.

Takimoto A, Mohri H, Kokubu C, Hiraki Y, Shukunami C.

Exp Cell Res. 2013 Dec 10;319(20):3128-39. doi: 10.1016/j.yexcr.2013.09.015. Epub 2013 Sep 27.

PMID:
24080012
14.

Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase.

Yamanishi A, Yusa K, Horie K, Tokunaga M, Kusano K, Kokubu C, Takeda J.

Genome Res. 2013 Sep;23(9):1462-73. doi: 10.1101/gr.152744.112. Epub 2013 Aug 1.

15.

A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening.

Horie K, Kokubu C, Yoshida J, Akagi K, Isotani A, Oshitani A, Yusa K, Ikeda R, Huang Y, Bradley A, Takeda J.

Nat Methods. 2011 Oct 23;8(12):1071-7. doi: 10.1038/nmeth.1739.

PMID:
22020066
16.

Functional genomics in the mouse using the sleeping beauty transposon system.

Horie K, Kokubu C, Takeda J.

Methods Enzymol. 2010;477:71-89. doi: 10.1016/S0076-6879(10)77005-1.

PMID:
20699137
17.

Delayed dopaminergic neuron differentiation in Lrp6 mutant mice.

Castelo-Branco G, Andersson ER, Minina E, Sousa KM, Ribeiro D, Kokubu C, Imai K, Prakash N, Wurst W, Arenas E.

Dev Dyn. 2010 Jan;239(1):211-21. doi: 10.1002/dvdy.22094.

18.

A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice.

Kokubu C, Horie K, Abe K, Ikeda R, Mizuno S, Uno Y, Ogiwara S, Ohtsuka M, Isotani A, Okabe M, Imai K, Takeda J.

Nat Genet. 2009 Aug;41(8):946-52. doi: 10.1038/ng.397. Epub 2009 Jul 26.

PMID:
19633672
19.

Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd.

Kubota T, Michigami T, Sakaguchi N, Kokubu C, Suzuki A, Namba N, Sakai N, Nakajima S, Imai K, Ozono K.

J Bone Miner Res. 2008 Oct;23(10):1661-71. doi: 10.1359/jbmr.080512.

20.

Wnt/Lrp/beta-catenin signaling suppresses adipogenesis by inhibiting mutual activation of PPARgamma and C/EBPalpha.

Kawai M, Mushiake S, Bessho K, Murakami M, Namba N, Kokubu C, Michigami T, Ozono K.

Biochem Biophys Res Commun. 2007 Nov 16;363(2):276-82. Epub 2007 Aug 27.

PMID:
17888405
21.

Sleeping beauty transposase has an affinity for heterochromatin conformation.

Ikeda R, Kokubu C, Yusa K, Keng VW, Horie K, Takeda J.

Mol Cell Biol. 2007 Mar;27(5):1665-76. Epub 2006 Dec 18.

22.

Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system.

Keng VW, Yae K, Hayakawa T, Mizuno S, Uno Y, Yusa K, Kokubu C, Kinoshita T, Akagi K, Jenkins NA, Copeland NG, Horie K, Takeda J.

Nat Methods. 2005 Oct;2(10):763-9.

PMID:
16179923
23.

Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.

Kokubu C, Heinzmann U, Kokubu T, Sakai N, Kubota T, Kawai M, Wahl MB, Galceran J, Grosschedl R, Ozono K, Imai K.

Development. 2004 Nov;131(21):5469-80. Epub 2004 Oct 6.

24.

Undulated short-tail deletion mutation in the mouse ablates Pax1 and leads to ectopic activation of neighboring Nkx2-2 in domains that normally express Pax1.

Kokubu C, Wilm B, Kokubu T, Wahl M, Rodrigo I, Sakai N, Santagati F, Hayashizaki Y, Suzuki M, Yamamura K, Abe K, Imai K.

Genetics. 2003 Sep;165(1):299-307.

25.

Mutation analysis of the acid ceramidase gene in Japanese patients with Farber disease.

Muramatsu T, Sakai N, Yanagihara I, Yamada M, Nishigaki T, Kokubu C, Tsukamoto H, Ito M, Inui K.

J Inherit Metab Dis. 2002 Nov;25(7):585-92.

PMID:
12638942
26.

Comparative analysis of the genomic organization of Pax9 and its conserved physical association with Nkx2-9 in the human, mouse, and pufferfish genomes.

Santagati F, Gerber JK, Blusch JH, Kokubu C, Peters H, Adamski J, Werner T, Balling R, Imai K.

Mamm Genome. 2001 Mar;12(3):232-7.

PMID:
11252173
27.

Mutation analysis of two Japanese patients with Fanconi-Bickel syndrome.

Akagi M, Inui K, Nakajima S, Shima M, Nishigaki T, Muramatsu T, Kokubu C, Tsukamoto H, Sakai N, Okada S.

J Hum Genet. 2000;45(1):60-2.

PMID:
10697967
28.

Mutation analysis of a Japanese patient with fucosidosis.

Akagi M, Inui K, Nishigaki T, Muramatsu T, Kokubu C, Fu L, Fukushima H, Yanagihara I, Tsukamoto H, Kurahashi H, Okada S.

J Hum Genet. 1999;44(5):323-6.

PMID:
10496076
29.

Molecular heterogeneity of Krabbe disease.

Fu L, Inui K, Nishigaki T, Tatsumi N, Tsukamoto H, Kokubu C, Muramatsu T, Okada S.

J Inherit Metab Dis. 1999 Apr;22(2):155-62.

PMID:
10234611

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