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Items: 29


Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2.

Kokontis JM, Lin HP, Jiang SS, Lin CY, Fukuchi J, Hiipakka RA, Chung CJ, Chan TM, Liao S, Chang CH, Chuu CP.

PLoS One. 2014 Oct 1;9(10):e109170. doi: 10.1371/journal.pone.0109170. eCollection 2014. Erratum in: PLoS One. 2014;9(10):e111731.


Cholestane-3β, 5α, 6β-triol suppresses proliferation, migration, and invasion of human prostate cancer cells.

Lin CY, Huo C, Kuo LK, Hiipakka RA, Jones RB, Lin HP, Hung Y, Su LC, Tseng JC, Kuo YY, Wang YL, Fukui Y, Kao YH, Kokontis JM, Yeh CC, Chen L, Yang SD, Fu HH, Chen YW, Tsai KK, Chang JY, Chuu CP.

PLoS One. 2013 Jun 13;8(6):e65734. doi: 10.1371/journal.pone.0065734. Print 2013.


Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks.

Chuu CP, Lin HP, Ciaccio MF, Kokontis JM, Hause RJ Jr, Hiipakka RA, Liao S, Jones RB.

Cancer Prev Res (Phila). 2012 May;5(5):788-97. doi: 10.1158/1940-6207.CAPR-12-0004-T.


Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer.

Chuu CP, Kokontis JM, Hiipakka RA, Fukuchi J, Lin HP, Lin CY, Huo C, Su LC.

J Biomed Sci. 2011 Aug 23;18:63. doi: 10.1186/1423-0127-18-63. Review.


Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.

Chuu CP, Kokontis JM, Hiipakka RA, Fukuchi J, Lin HP, Lin CY, Huo C, Su LC, Liao S.

Cancer Sci. 2011 Nov;102(11):2022-8. doi: 10.1111/j.1349-7006.2011.02043.x. Epub 2011 Aug 18. Erratum in: Cancer Sci. 2013 Jan;104(1):142. Huo, Chiech [corrected to Huo, Chieh].


The effect of diet on the response of low-density lipoprotein receptor knockout mice to the liver X receptor agonist T1317.

Peng L, Hiipakka RA, Xie JT, Kokontis JM, Liao S, Peng D.

J Cardiovasc Pharmacol. 2011 Jul;58(1):102-10. doi: 10.1097/FJC.0b013e31821d1168.


A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(-/-) mice.

Peng D, Hiipakka RA, Xie JT, Dai Q, Kokontis JM, Reardon CA, Getz GS, Liao S.

Br J Pharmacol. 2011 Apr;162(8):1792-804. doi: 10.1111/j.1476-5381.2011.01202.x.


Suppression of androgen receptor signaling and prostate specific antigen expression by (-)-epigallocatechin-3-gallate in different progression stages of LNCaP prostate cancer cells.

Chuu CP, Chen RY, Kokontis JM, Hiipakka RA, Liao S.

Cancer Lett. 2009 Mar 8;275(1):86-92. doi: 10.1016/j.canlet.2008.10.001. Epub 2008 Nov 1.


The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells.

Chuu CP, Chen RY, Hiipakka RA, Kokontis JM, Warner KV, Xiang J, Liao S.

Biochem Biophys Res Commun. 2007 Jun 1;357(2):341-6. Epub 2007 Mar 28.


Modulation of liver X receptor signaling as novel therapy for prostate cancer.

Chuu CP, Kokontis JM, Hiipakka RA, Liao S.

J Biomed Sci. 2007 Sep;14(5):543-53. Epub 2007 Mar 20. Review.


Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist.

Chuu CP, Hiipakka RA, Kokontis JM, Fukuchi J, Chen RY, Liao S.

Cancer Res. 2006 Jul 1;66(13):6482-6.


Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity.

Kokontis JM, Hsu S, Chuu CP, Dang M, Fukuchi J, Hiipakka RA, Liao S.

Prostate. 2005 Dec 1;65(4):287-98.


Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells.

Fukuchi J, Kokontis JM, Hiipakka RA, Chuu CP, Liao S.

Cancer Res. 2004 Nov 1;64(21):7686-9.


Androgenic suppression of ATP-binding cassette transporter A1 expression in LNCaP human prostate cancer cells.

Fukuchi J, Hiipakka RA, Kokontis JM, Hsu S, Ko AL, Fitzgerald ML, Liao S.

Cancer Res. 2004 Nov 1;64(21):7682-5.


TATA-binding protein-associated factor 7 regulates polyamine transport activity and polyamine analog-induced apoptosis.

Fukuchi J, Hiipakka RA, Kokontis JM, Nishimura K, Igarashi K, Liao S.

J Biol Chem. 2004 Jul 16;279(29):29921-9. Epub 2004 Apr 12.


A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function.

Kokontis JM, Wagner AJ, O'Leary M, Liao S, Hay N.

Oncogene. 2001 Feb 8;20(6):659-68.


Molecular action of androgen in the normal and neoplastic prostate.

Kokontis JM, Liao S.

Vitam Horm. 1999;55:219-307. Review. No abstract available.


Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride.

Umekita Y, Hiipakka RA, Kokontis JM, Liao S.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11802-7.


Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate.

Liao S, Umekita Y, Guo J, Kokontis JM, Hiipakka RA.

Cancer Lett. 1995 Sep 25;96(2):239-43.


Ubiquitous receptor: structures, immunocytochemical localization, and modulation of gene activation by receptors for retinoic acids and thyroid hormones.

Song C, Hiipakka RA, Kokontis JM, Liao S.

Ann N Y Acad Sci. 1995 Jun 12;761:38-49. Review. No abstract available.


Assignment of the human ubiquitous receptor gene (UNR) to 19q13.3 using fluorescence in situ hybridization.

Le Beau MM, Song C, Davis EM, Hiipakka RA, Kokontis JM, Liao S.

Genomics. 1995 Mar 1;26(1):166-8. No abstract available.


Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.

Song C, Kokontis JM, Hiipakka RA, Liao S.

Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10809-13.


Mutation in Escherichia coli and mammalian cells induced by closely spaced 1-methylpyrene-deoxyadenosine adducts in opposite DNA strands.

Kokontis JM, Tsung SS, Vaughan-Johnson J, Lee H, Harvey RG, Weiss SB.

Carcinogenesis. 1993 Apr;14(4):645-51.


Illegitimate recombination induced by benzo[a]pyrene diol epoxide in Escherichia coli.

Kokontis JM, Vaughan J, Harvey RG, Weiss SB.

Proc Natl Acad Sci U S A. 1988 Feb;85(4):1043-6.


Spontaneous and induced mitotic recombination in Ustilago violacea detected at the cellular level.

Kokontis JM, Garber ED.

Curr Genet. 1983 Nov;7(6):465-71. doi: 10.1007/BF00377612.


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