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Items: 1 to 50 of 77

1.

Immunohistochemical expression of PD-L1 in early and late stage non-small cell lung cancer: Correlation with clinicopathological and molecular features.

Kokkotou E, Rapti V, Grapsa D, Bakakos P, Papadopoulos S, Bobos M, Iliadis K, Syrigos K.

Ann Oncol. 2019 Apr;30 Suppl 2:ii5. doi: 10.1093/annonc/mdz072.016. No abstract available.

2.

Current and future roles of biosimilars in oncology practice.

Konstantinidou S, Papaspiliou A, Kokkotou E.

Oncol Lett. 2020 Jan;19(1):45-51. doi: 10.3892/ol.2019.11105. Epub 2019 Nov 15. Review.

3.

Lung cancer patients' journey from first symptom to treatment: Results from a Greek registry.

Kourlaba G, Gkiozos I, Kokkotou E, Stefanou G, Papaspiliou A, Syrigos K.

Cancer Epidemiol. 2019 Jun;60:193-200. doi: 10.1016/j.canep.2019.04.014. Epub 2019 May 4.

PMID:
31063908
4.

Hematopoietic Stem/Progenitor Cell Dependent Participation of Innate Lymphoid Cells in Low-Intensity Sterile Inflammation.

Korniotis S, Thornley TB, Kyriazis P, Theodorou E, Ma L, Li LS, Kokkotou E, Strom TB, Koulmanda M.

Front Immunol. 2018 Sep 5;9:2007. doi: 10.3389/fimmu.2018.02007. eCollection 2018.

5.

Reproducing the human mucosal environment ex vivo: inflammatory bowel disease as a paradigm.

Swanson KD, Theodorou E, Kokkotou E.

Curr Opin Gastroenterol. 2018 Nov;34(6):384-391. doi: 10.1097/MOG.0000000000000485. Review.

PMID:
30188406
6.

Identification of novel mRNAs and lncRNAs associated with mouse experimental colitis and human inflammatory bowel disease.

Rankin CR, Theodorou E, Man Law IK, Rowe L, Kokkotou E, Pekow J, Wang J, Martín MG, Pothoulakis C, Padua D.

Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G722-G733. doi: 10.1152/ajpgi.00077.2018. Epub 2018 Jun 28.

7.

Screening for novel central nervous system biomarkers in veterans with Gulf War Illness.

Abou-Donia MB, Conboy LA, Kokkotou E, Jacobson E, Elmasry EM, Elkafrawy P, Neely M, Bass CR', Sullivan K.

Neurotoxicol Teratol. 2017 May;61:36-46. doi: 10.1016/j.ntt.2017.03.002. Epub 2017 Mar 9.

PMID:
28286177
8.

Role of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses.

Bai A, Kokkotou E, Zheng Y, Robson SC.

Cell Death Dis. 2015 Jul 23;6:e1828. doi: 10.1038/cddis.2015.178.

9.

Substance P promotes wound healing in diabetes by modulating inflammation and macrophage phenotype.

Leal EC, Carvalho E, Tellechea A, Kafanas A, Tecilazich F, Kearney C, Kuchibhotla S, Auster ME, Kokkotou E, Mooney DJ, LoGerfo FW, Pradhan-Nabzdyk L, Veves A.

Am J Pathol. 2015 Jun;185(6):1638-48. doi: 10.1016/j.ajpath.2015.02.011. Epub 2015 Apr 11.

10.

A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium.

Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D.

Inflamm Bowel Dis. 2015 May;21(5):996-1005. doi: 10.1097/MIB.0000000000000339.

11.

Conscientiousness is modified by genetic variation in catechol-O-methyltransferase to reduce symptom complaints in IBS patients.

Hall KT, Tolkin BR, Chinn GM, Kirsch I, Kelley JM, Lembo AJ, Kaptchuk TJ, Kokkotou E, Davis RB, Conboy LA.

Brain Behav. 2015 Jan;5(1):39-44. doi: 10.1002/brb3.294. Epub 2014 Nov 13.

12.

CD39 and CD161 modulate Th17 responses in Crohn's disease.

Bai A, Moss A, Kokkotou E, Usheva A, Sun X, Cheifetz A, Zheng Y, Longhi MS, Gao W, Wu Y, Robson SC.

J Immunol. 2014 Oct 1;193(7):3366-77. doi: 10.4049/jimmunol.1400346. Epub 2014 Aug 29.

13.

Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10.

Ziogas DC, Karagiannis AK, Geiger BM, Gras-Miralles B, Najarian R, Reizes O, Fitzpatrick LR, Kokkotou E.

Peptides. 2014 May;55:58-64. doi: 10.1016/j.peptides.2014.02.005. Epub 2014 Feb 18.

14.

Intestinal upregulation of melanin-concentrating hormone in TNBS-induced enterocolitis in adult zebrafish.

Geiger BM, Gras-Miralles B, Ziogas DC, Karagiannis AK, Zhen A, Fraenkel P, Kokkotou E.

PLoS One. 2013 Dec 20;8(12):e83194. doi: 10.1371/journal.pone.0083194. eCollection 2013.

15.

Tumor necrosis factor-neuropeptide Y cross talk regulates inflammation, epithelial barrier functions, and colonic motility.

Chandrasekharan B, Jeppsson S, Pienkowski S, Belsham DD, Sitaraman SV, Merlin D, Kokkotou E, Nusrat A, Tansey MG, Srinivasan S.

Inflamm Bowel Dis. 2013 Nov;19(12):2535-46. doi: 10.1097/01.MIB.0000437042.59208.9f.

16.

MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis.

Koukos G, Polytarchou C, Kaplan JL, Morley-Fletcher A, Gras-Miralles B, Kokkotou E, Baril-Dore M, Pothoulakis C, Winter HS, Iliopoulos D.

Gastroenterology. 2013 Oct;145(4):842-52.e2. doi: 10.1053/j.gastro.2013.07.001. Epub 2013 Jul 12.

17.

Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis.

Ziogas DC, Gras-Miralles B, Mustafa S, Geiger BM, Najarian RM, Nagel JM, Flier SN, Popov Y, Tseng YH, Kokkotou E.

Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G876-84. doi: 10.1152/ajpgi.00305.2012. Epub 2013 Mar 28.

18.

Increased susceptibility of melanin-concentrating hormone-deficient mice to infection with Salmonella enterica serovar Typhimurium.

Karagiannis AK, Ziogas DC, Gras-Miralles B, Geiger BM, Nagel J, Trebicka E, Najarian R, Cherayil BJ, Kokkotou E.

Infect Immun. 2013 Jan;81(1):166-72. doi: 10.1128/IAI.00572-12. Epub 2012 Oct 31.

19.

Catechol-O-methyltransferase val158met polymorphism predicts placebo effect in irritable bowel syndrome.

Hall KT, Lembo AJ, Kirsch I, Ziogas DC, Douaiher J, Jensen KB, Conboy LA, Kelley JM, Kokkotou E, Kaptchuk TJ.

PLoS One. 2012;7(10):e48135. doi: 10.1371/journal.pone.0048135. Epub 2012 Oct 23.

20.

Reduced intestinal tumorigenesis in APCmin mice lacking melanin-concentrating hormone.

Nagel JM, Geiger BM, Karagiannis AK, Gras-Miralles B, Horst D, Najarian RM, Ziogas DC, Chen X, Kokkotou E.

PLoS One. 2012;7(7):e41914. doi: 10.1371/journal.pone.0041914. Epub 2012 Jul 27.

21.

Dyslipidemia in granuloma annulare: a case-control study.

Wu W, Robinson-Bostom L, Kokkotou E, Jung HY, Kroumpouzos G.

Arch Dermatol. 2012 Oct;148(10):1131-6.

PMID:
22710282
22.

Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway.

Townsend KL, Suzuki R, Huang TL, Jing E, Schulz TJ, Lee K, Taniguchi CM, Espinoza DO, McDougall LE, Zhang H, He TC, Kokkotou E, Tseng YH.

FASEB J. 2012 May;26(5):2187-96. doi: 10.1096/fj.11-199067. Epub 2012 Feb 13.

23.

Role of substance P in the regulation of glucose metabolism via insulin signaling-associated pathways.

Karagiannides I, Bakirtzi K, Kokkotou E, Stavrakis D, Margolis KG, Thomou T, Giorgadze N, Kirkland JL, Pothoulakis C.

Endocrinology. 2011 Dec;152(12):4571-80. doi: 10.1210/en.2011-1170. Epub 2011 Oct 18.

24.

Substance P (SP)-neurokinin-1 receptor (NK-1R) alters adipose tissue responses to high-fat diet and insulin action.

Karagiannides I, Stavrakis D, Bakirtzi K, Kokkotou E, Pirtskhalava T, Nayeb-Hashemi H, Bowe C, Bugni JM, Nuño M, Lu B, Gerard NP, Leeman SE, Kirkland JL, Pothoulakis C.

Endocrinology. 2011 Jun;152(6):2197-205. doi: 10.1210/en.2010-1345. Epub 2011 Apr 5.

25.

Placebos without deception: a randomized controlled trial in irritable bowel syndrome.

Kaptchuk TJ, Friedlander E, Kelley JM, Sanchez MN, Kokkotou E, Singer JP, Kowalczykowski M, Miller FG, Kirsch I, Lembo AJ.

PLoS One. 2010 Dec 22;5(12):e15591. doi: 10.1371/journal.pone.0015591.

26.

You deserve what you eat: lessons learned from the study of the melanin-concentrating hormone (MCH)-deficient mice.

Wang Y, Ziogas DC, Biddinger S, Kokkotou E.

Gut. 2010 Dec;59(12):1625-34. doi: 10.1136/gut.2010.210526. Epub 2010 Oct 21.

27.

Corticotropin-releasing factor regulates TLR4 expression in the colon and protects mice from colitis.

Chaniotou Z, Giannogonas P, Theoharis S, Teli T, Gay J, Savidge T, Koutmani Y, Brugni J, Kokkotou E, Pothoulakis C, Karalis KP.

Gastroenterology. 2010 Dec;139(6):2083-92. doi: 10.1053/j.gastro.2010.08.024. Epub 2010 Aug 20.

PMID:
20732324
28.

Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R.

J Biol Chem. 2010 Jun 25;285(26):20202-12. doi: 10.1074/jbc.M110.102012. Epub 2010 Apr 2.

29.

Meta-analysis: the effects of placebo treatment on gastro-oesophageal reflux disease.

Cremonini F, Ziogas DC, Chang HY, Kokkotou E, Kelley JM, Conboy L, Kaptchuk TJ, Lembo AJ.

Aliment Pharmacol Ther. 2010 Jul;32(1):29-42. doi: 10.1111/j.1365-2036.2010.04315.x. Epub 2010 Mar 26.

30.

Serum correlates of the placebo effect in irritable bowel syndrome.

Kokkotou E, Conboy LA, Ziogas DC, Quilty MT, Kelley JM, Davis RB, Lembo AJ, Kaptchuk TJ.

Neurogastroenterol Motil. 2010 Mar;22(3):285-e81. doi: 10.1111/j.1365-2982.2009.01440.x. Epub 2009 Dec 22.

31.

Which patients improve: characteristics increasing sensitivity to a supportive patient-practitioner relationship.

Conboy LA, Macklin E, Kelley J, Kokkotou E, Lembo A, Kaptchuk T.

Soc Sci Med. 2010 Feb;70(3):479-484. doi: 10.1016/j.socscimed.2009.10.024. Epub 2009 Nov 10.

32.

Activation of phosphatidylinositol 3-kinase/protein kinase B by corticotropin-releasing factor in human monocytes.

Chandras C, Koutmani Y, Kokkotou E, Pothoulakis C, Karalis KP.

Endocrinology. 2009 Oct;150(10):4606-14. doi: 10.1210/en.2008-1810. Epub 2009 Jul 23.

33.

Saccharomyces boulardii inhibits EGF receptor signaling and intestinal tumor growth in Apc(min) mice.

Chen X, Fruehauf J, Goldsmith JD, Xu H, Katchar KK, Koon HW, Zhao D, Kokkotou EG, Pothoulakis C, Kelly CP.

Gastroenterology. 2009 Sep;137(3):914-23. doi: 10.1053/j.gastro.2009.05.050. Epub 2009 May 29.

34.

Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice.

Kokkotou E, Espinoza DO, Torres D, Karagiannides I, Kosteletos S, Savidge T, O'Brien M, Pothoulakis C.

Gut. 2009 Jan;58(1):34-40. doi: 10.1136/gut.2008.155341. Epub 2008 Sep 29.

35.

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.

Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR.

Nature. 2008 Aug 21;454(7207):1000-4. doi: 10.1038/nature07221.

36.

Melanin-concentrating hormone as a mediator of intestinal inflammation.

Kokkotou E, Moss AC, Torres D, Karagiannides I, Cheifetz A, Liu S, O'Brien M, Maratos-Flier E, Pothoulakis C.

Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10613-8. doi: 10.1073/pnas.0804536105. Epub 2008 Jul 23.

37.

Evidence for defective mesolimbic dopamine exocytosis in obesity-prone rats.

Geiger BM, Behr GG, Frank LE, Caldera-Siu AD, Beinfeld MC, Kokkotou EG, Pothos EN.

FASEB J. 2008 Aug;22(8):2740-6. doi: 10.1096/fj.08-110759. Epub 2008 May 13.

38.

Corticotropin-releasing hormone deficiency is associated with reduced local inflammation in a mouse model of experimental colitis.

Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP.

Endocrinology. 2008 Jul;149(7):3403-9. doi: 10.1210/en.2007-1703. Epub 2008 Apr 10.

39.

Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome.

Kaptchuk TJ, Kelley JM, Conboy LA, Davis RB, Kerr CE, Jacobson EE, Kirsch I, Schyner RN, Nam BH, Nguyen LT, Park M, Rivers AL, McManus C, Kokkotou E, Drossman DA, Goldman P, Lembo AJ.

BMJ. 2008 May 3;336(7651):999-1003. doi: 10.1136/bmj.39524.439618.25. Epub 2008 Apr 3.

40.

Substance P as a novel anti-obesity target.

Karagiannides I, Torres D, Tseng YH, Bowe C, Carvalho E, Espinoza D, Pothoulakis C, Kokkotou E.

Gastroenterology. 2008 Mar;134(3):747-55. doi: 10.1053/j.gastro.2007.12.032.

41.

Comparative efficacies of rifaximin and vancomycin for treatment of Clostridium difficile-associated diarrhea and prevention of disease recurrence in hamsters.

Kokkotou E, Moss AC, Michos A, Espinoza D, Cloud JW, Mustafa N, O'Brien M, Pothoulakis C, Kelly CP.

Antimicrob Agents Chemother. 2008 Mar;52(3):1121-6. doi: 10.1128/AAC.01143-07. Epub 2008 Jan 14.

42.

High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice.

Cohen SE, Kokkotou E, Biddinger SB, Kondo T, Gebhardt R, Kratzsch J, Mantzoros CS, Kahn CR.

J Biol Chem. 2007 Aug 10;282(32):23672-8. Epub 2007 Jun 7.

43.

Urocortin II mediates pro-inflammatory effects in human colonocytes via corticotropin-releasing hormone receptor 2alpha.

Moss AC, Anton P, Savidge T, Newman P, Cheifetz AS, Gay J, Paraschos S, Winter MW, Moyer MP, Karalis K, Kokkotou E, Pothoulakis C.

Gut. 2007 Sep;56(9):1210-7. Epub 2007 Apr 5.

44.

Melanin concentrating hormone is a novel regulator of islet function and growth.

Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.

Diabetes. 2007 Feb;56(2):311-9.

45.

Interleukin-6 genetic ablation protects from trinitrobenzene sulfonic acid-induced colitis in mice. Putative effect of antiinflammatory cytokines.

Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP.

Neuroimmunomodulation. 2006;13(2):114-21. Epub 2006 Oct 14.

PMID:
17077645
46.

Corticotropin-releasing hormone receptor 2-deficient mice have reduced intestinal inflammatory responses.

Kokkotou E, Torres D, Moss AC, O'Brien M, Grigoriadis DE, Karalis K, Pothoulakis C.

J Immunol. 2006 Sep 1;177(5):3355-61.

47.

Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis.

Chen X, Kokkotou EG, Mustafa N, Bhaskar KR, Sougioultzis S, O'Brien M, Pothoulakis C, Kelly CP.

J Biol Chem. 2006 Aug 25;281(34):24449-54. Epub 2006 Jun 30.

48.

The physiology and potential clinical applications of ghrelin, a novel peptide hormone.

Tritos NA, Kokkotou EG.

Mayo Clin Proc. 2006 May;81(5):653-60. Review.

PMID:
16706263
49.

The role of neurokinin 1 receptors in the maintenance of visceral hyperalgesia induced by repeated stress in rats.

Bradesi S, Kokkotou E, Simeonidis S, Patierno S, Ennes HS, Mittal Y, McRoberts JA, Ohning G, McLean P, Marvizon JC, Sternini C, Pothoulakis C, Mayer EA.

Gastroenterology. 2006 May;130(6):1729-42.

PMID:
16697737
50.

Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes.

Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O'Brien M, Leeman SE, Kirkland JL, Pothoulakis C.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5207-12. Epub 2006 Mar 20.

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