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Items: 1 to 50 of 150

1.

Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death.

Ajmone-Cat MA, Onori A, Toselli C, Stronati E, Morlando M, Bozzoni I, Monni E, Kokaia Z, Lupo G, Minghetti L, Biagioni S, Cacci E.

Sci Rep. 2019 Mar 14;9(1):4572. doi: 10.1038/s41598-019-41040-4.

2.

In Vitro Functional Characterization of Human Neurons and Astrocytes Using Calcium Imaging and Electrophysiology.

Hansen MG, Tornero D, Canals I, Ahlenius H, Kokaia Z.

Methods Mol Biol. 2019;1919:73-88. doi: 10.1007/978-1-4939-9007-8_6.

PMID:
30656622
3.

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging.

Säwen P, Eldeeb M, Erlandsson E, Kristiansen TA, Laterza C, Kokaia Z, Karlsson G, Yuan J, Soneji S, Mandal PK, Rossi DJ, Bryder D.

Elife. 2018 Dec 18;7. pii: e41258. doi: 10.7554/eLife.41258.

4.

Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers.

Miskinyte G, Grønning Hansen M, Monni E, Lam M, Bengzon J, Lindvall O, Ahlenius H, Kokaia Z.

PLoS One. 2018 Oct 11;13(10):e0204688. doi: 10.1371/journal.pone.0204688. eCollection 2018.

5.

Human Neural Stem Cells for Ischemic Stroke Treatment.

Kokaia Z, Darsalia V.

Results Probl Cell Differ. 2018;66:249-263. doi: 10.1007/978-3-319-93485-3_11.

PMID:
30209663
6.

Customized Brain Cells for Stroke Patients Using Pluripotent Stem Cells.

Kokaia Z, Llorente IL, Carmichael ST.

Stroke. 2018 May;49(5):1091-1098. doi: 10.1161/STROKEAHA.117.018291. Epub 2018 Apr 18. Review. No abstract available.

7.

Sensors of Succinate: Neural Stem Cell Grafts Fight Neuroinflammation.

Kokaia Z, Lindvall O.

Cell Stem Cell. 2018 Mar 1;22(3):283-285. doi: 10.1016/j.stem.2018.01.019.

8.

Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors.

Laterza C, Uoshima N, Tornero D, Wilhelmsson U, Stokowska A, Ge R, Pekny M, Lindvall O, Kokaia Z.

PLoS One. 2018 Feb 5;13(2):e0192118. doi: 10.1371/journal.pone.0192118. eCollection 2018.

9.

Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks.

Miskinyte G, Devaraju K, Grønning Hansen M, Monni E, Tornero D, Woods NB, Bengzon J, Ahlenius H, Lindvall O, Kokaia Z.

Stem Cell Res Ther. 2017 Sep 29;8(1):207. doi: 10.1186/s13287-017-0658-3.

10.

Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke.

Ge R, Tornero D, Hirota M, Monni E, Laterza C, Lindvall O, Kokaia Z.

J Neuroinflammation. 2017 Jul 28;14(1):153. doi: 10.1186/s12974-017-0909-3.

11.

Monocyte depletion early after stroke promotes neurogenesis from endogenous neural stem cells in adult brain.

Laterza C, Wattananit S, Uoshima N, Ge R, Pekny R, Tornero D, Monni E, Lindvall O, Kokaia Z.

Exp Neurol. 2017 Nov;297:129-137. doi: 10.1016/j.expneurol.2017.07.012. Epub 2017 Jul 23.

PMID:
28746827
12.

Transplantation of reprogrammed neurons for improved recovery after stroke.

Kokaia Z, Tornero D, Lindvall O.

Prog Brain Res. 2017;231:245-263. doi: 10.1016/bs.pbr.2016.11.013. Epub 2017 Jan 6. Review.

PMID:
28554399
13.

Stroke alters behavior of human skin-derived neural progenitors after transplantation adjacent to neurogenic area in rat brain.

de la Rosa-Prieto C, Laterza C, Gonzalez-Ramos A, Wattananit S, Ge R, Lindvall O, Tornero D, Kokaia Z.

Stem Cell Res Ther. 2017 Mar 9;8(1):59. doi: 10.1186/s13287-017-0513-6.

14.

Spontaneous Recovery of Upper Extremity Motor Impairment After Ischemic Stroke: Implications for Stem Cell-Based Therapeutic Approaches.

Delavaran H, Aked J, Sjunnesson H, Lindvall O, Norrving B, Kokaia Z, Lindgren A.

Transl Stroke Res. 2017 Aug;8(4):351-361. doi: 10.1007/s12975-017-0523-9. Epub 2017 Feb 15.

15.

Attitudes to Stem Cell Therapy Among Ischemic Stroke Survivors in the Lund Stroke Recovery Study.

Aked J, Delavaran H, Lindvall O, Norrving B, Kokaia Z, Lindgren A.

Stem Cells Dev. 2017 Apr 15;26(8):566-572. doi: 10.1089/scd.2016.0343. Epub 2017 Feb 28.

PMID:
28142330
16.

Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.

Tornero D, Tsupykov O, Granmo M, Rodriguez C, Grønning-Hansen M, Thelin J, Smozhanik E, Laterza C, Wattananit S, Ge R, Tatarishvili J, Grealish S, Brüstle O, Skibo G, Parmar M, Schouenborg J, Lindvall O, Kokaia Z.

Brain. 2017 Mar 1;140(3):692-706. doi: 10.1093/brain/aww347.

PMID:
28115364
17.

Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice.

Wattananit S, Tornero D, Graubardt N, Memanishvili T, Monni E, Tatarishvili J, Miskinyte G, Ge R, Ahlenius H, Lindvall O, Schwartz M, Kokaia Z.

J Neurosci. 2016 Apr 13;36(15):4182-95. doi: 10.1523/JNEUROSCI.4317-15.2016.

18.

Generation of cortical neurons from human induced-pluripotent stem cells by biodegradable polymeric microspheres loaded with priming factors.

Memanishvili T, Kupatadze N, Tugushi D, Katsarava R, Wattananit S, Hara N, Tornero D, Kokaia Z.

Biomed Mater. 2016 Mar 23;11(2):025011. doi: 10.1088/1748-6041/11/2/025011.

PMID:
27007569
19.

Neurogenesis following Stroke Affecting the Adult Brain.

Lindvall O, Kokaia Z.

Cold Spring Harb Perspect Biol. 2015 Nov 2;7(11). pii: a019034. doi: 10.1101/cshperspect.a019034. Review.

20.

Inflammation without neuronal death triggers striatal neurogenesis comparable to stroke.

Chapman KZ, Ge R, Monni E, Tatarishvili J, Ahlenius H, Arvidsson A, Ekdahl CT, Lindvall O, Kokaia Z.

Neurobiol Dis. 2015 Nov;83:1-15. doi: 10.1016/j.nbd.2015.08.013. Epub 2015 Aug 20.

PMID:
26299391
21.

TARGETING NEUROINFLAMMATION FOR TREATMENT OF ISCHEMIC STROKE.

Kokaia Z.

Georgian Med News. 2015 Jun;(243):84-7.

PMID:
26087739
22.

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse.

Magnusson JP, Göritz C, Tatarishvili J, Dias DO, Smith EM, Lindvall O, Kokaia Z, Frisén J.

Science. 2014 Oct 10;346(6206):237-41. doi: 10.1126/science.346.6206.237. Epub 2014 Oct 9.

23.

Human induced pluripotent stem cells improve recovery in stroke-injured aged rats.

Tatarishvili J, Oki K, Monni E, Koch P, Memanishvili T, Buga AM, Verma V, Popa-Wagner A, Brüstle O, Lindvall O, Kokaia Z.

Restor Neurol Neurosci. 2014;32(4):547-58. doi: 10.3233/RNN-140404.

PMID:
24916776
24.

The age and genomic integrity of neurons after cortical stroke in humans.

Huttner HB, Bergmann O, Salehpour M, Rácz A, Tatarishvili J, Lindgren E, Csonka T, Csiba L, Hortobágyi T, Méhes G, Englund E, Solnestam BW, Zdunek S, Scharenberg C, Ström L, Ståhl P, Sigurgeirsson B, Dahl A, Schwab S, Possnert G, Bernard S, Kokaia Z, Lindvall O, Lundeberg J, Frisén J.

Nat Neurosci. 2014 Jun;17(6):801-3. doi: 10.1038/nn.3706. Epub 2014 Apr 20.

PMID:
24747576
25.

Human fetal striatum-derived neural stem (NS) cells differentiate to mature neurons in vitro and in vivo.

Monni E, Cusulin C, Cavallaro M, Lindvall O, Kokaia Z.

Curr Stem Cell Res Ther. 2014;9(4):338-46.

PMID:
24654649
26.

Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery.

Tornero D, Wattananit S, Grønning Madsen M, Koch P, Wood J, Tatarishvili J, Mine Y, Ge R, Monni E, Devaraju K, Hevner RF, Brüstle O, Lindvall O, Kokaia Z.

Brain. 2013 Dec;136(Pt 12):3561-77. doi: 10.1093/brain/awt278. Epub 2013 Oct 21.

PMID:
24148272
27.

FoxJ1-expressing cells contribute to neurogenesis in forebrain of adult rats: evidence from in vivo electroporation combined with piggyBac transposon.

Devaraju K, Barnabé-Heider F, Kokaia Z, Lindvall O.

Exp Cell Res. 2013 Nov 1;319(18):2790-800. doi: 10.1016/j.yexcr.2013.08.028. Epub 2013 Sep 25.

PMID:
24075965
28.

Grafted human neural stem cells enhance several steps of endogenous neurogenesis and improve behavioral recovery after middle cerebral artery occlusion in rats.

Mine Y, Tatarishvili J, Oki K, Monni E, Kokaia Z, Lindvall O.

Neurobiol Dis. 2013 Apr;52:191-203. doi: 10.1016/j.nbd.2012.12.006. Epub 2012 Dec 28.

PMID:
23276704
29.

Stem cell repair of striatal ischemia.

Kokaia Z, Lindvall O.

Prog Brain Res. 2012;201:35-53. doi: 10.1016/B978-0-444-59544-7.00003-2. Review.

PMID:
23186709
30.

Proximity of brain infarcts to regions of endogenous neurogenesis and involvement of striatum in ischaemic stroke.

Delavaran H, Sjunnesson H, Arvidsson A, Lindvall O, Norrving B, van Westen D, Kokaia Z, Lindgren A.

Eur J Neurol. 2013 Mar;20(3):473-9. doi: 10.1111/j.1468-1331.2012.03877.x. Epub 2012 Oct 11.

PMID:
23057628
31.

Embryonic stem cell-derived neural stem cells fuse with microglia and mature neurons.

Cusulin C, Monni E, Ahlenius H, Wood J, Brune JC, Lindvall O, Kokaia Z.

Stem Cells. 2012 Dec;30(12):2657-71. doi: 10.1002/stem.1227.

32.

Cross-talk between neural stem cells and immune cells: the key to better brain repair?

Kokaia Z, Martino G, Schwartz M, Lindvall O.

Nat Neurosci. 2012 Jul 26;15(8):1078-87. doi: 10.1038/nn.3163. Review.

PMID:
22837038
33.

Societal value of stem cell therapy in stroke--a modeling study.

Svensson J, Ghatnekar O, Lindgren A, Lindvall O, Norrving B, Persson U, Kokaia Z.

Cerebrovasc Dis. 2012;33(6):532-9. doi: 10.1159/000337765. Epub 2012 May 9.

34.

Ectopic ependymal cells in striatum accompany neurogenesis in a rat model of stroke.

Danilov AI, Kokaia Z, Lindvall O.

Neuroscience. 2012 Jul 12;214:159-70. doi: 10.1016/j.neuroscience.2012.03.062. Epub 2012 Apr 21.

PMID:
22531371
35.

Adaptor protein LNK is a negative regulator of brain neural stem cell proliferation after stroke.

Ahlenius H, Devaraju K, Monni E, Oki K, Wattananit S, Darsalia V, Iosif RE, Torper O, Wood JC, Braun S, Jagemann L, Nuber UA, Englund E, Jacobsen SE, Lindvall O, Kokaia Z.

J Neurosci. 2012 Apr 11;32(15):5151-64. doi: 10.1523/JNEUROSCI.0474-12.2012.

36.

Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain.

Oki K, Tatarishvili J, Wood J, Koch P, Wattananit S, Mine Y, Monni E, Tornero D, Ahlenius H, Ladewig J, Brüstle O, Lindvall O, Kokaia Z.

Stem Cells. 2012 Jun;30(6):1120-33. doi: 10.1002/stem.1104.

37.

Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis.

Wang Z, Andrade N, Torp M, Wattananit S, Arvidsson A, Kokaia Z, Jørgensen JR, Lindvall O.

J Cereb Blood Flow Metab. 2012 Feb;32(2):387-98. doi: 10.1038/jcbfm.2011.156. Epub 2011 Nov 2.

38.

Neural stem cell-based therapy for ischemic stroke.

Kokaia Z, Darsalia V.

Transl Stroke Res. 2011 Sep;2(3):272-8. doi: 10.1007/s12975-011-0100-6. Epub 2011 Aug 11.

PMID:
24323649
39.

Stem cell research in stroke: how far from the clinic?

Lindvall O, Kokaia Z.

Stroke. 2011 Aug;42(8):2369-75. doi: 10.1161/STROKEAHA.110.599654. Epub 2011 Jul 14. Review.

PMID:
21757669
40.

Spatio-temporal dynamics, differentiation and viability of human neural stem cells after implantation into neonatal rat brain.

Kallur T, Farr TD, Böhm-Sturm P, Kokaia Z, Hoehn M.

Eur J Neurosci. 2011 Aug;34(3):382-93. doi: 10.1111/j.1460-9568.2011.07759.x. Epub 2011 Jun 27.

PMID:
21707793
41.

Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment.

Wood JC, Jackson JS, Jakubs K, Chapman KZ, Ekdahl CT, Kokaia Z, Kokaia M, Lindvall O.

Exp Neurol. 2011 Jun;229(2):484-93. doi: 10.1016/j.expneurol.2011.03.019. Epub 2011 Apr 1.

PMID:
21459089
42.

Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke.

Heldmann U, Mine Y, Kokaia Z, Ekdahl CT, Lindvall O.

Exp Neurol. 2011 Jun;229(2):391-8. doi: 10.1016/j.expneurol.2011.03.005. Epub 2011 Mar 16.

PMID:
21419118
43.

Cell number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain.

Darsalia V, Allison SJ, Cusulin C, Monni E, Kuzdas D, Kallur T, Lindvall O, Kokaia Z.

J Cereb Blood Flow Metab. 2011 Jan;31(1):235-42. doi: 10.1038/jcbfm.2010.81. Epub 2010 Jun 9.

44.

Isolation and generation of neurosphere cultures from embryonic and adult mouse brain.

Ahlenius H, Kokaia Z.

Methods Mol Biol. 2010;633:241-52. doi: 10.1007/978-1-59745-019-5_18.

PMID:
20204633
45.

Stem cells in human neurodegenerative disorders--time for clinical translation?

Lindvall O, Kokaia Z.

J Clin Invest. 2010 Jan;120(1):29-40. doi: 10.1172/JCI40543. Review.

46.

Perturbed cellular response to brain injury during aging.

Popa-Wagner A, Buga AM, Kokaia Z.

Ageing Res Rev. 2011 Jan;10(1):71-9. doi: 10.1016/j.arr.2009.10.008. Epub 2009 Nov 10. Review.

PMID:
19900590
47.

Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling.

Koch P, Kokaia Z, Lindvall O, Brüstle O.

Lancet Neurol. 2009 Sep;8(9):819-29. doi: 10.1016/S1474-4422(09)70202-9. Review.

PMID:
19679274
48.

Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease.

Lindvall O, Kokaia Z.

Trends Pharmacol Sci. 2009 May;30(5):260-7. doi: 10.1016/j.tips.2009.03.001. Epub 2009 Apr 9. Review.

PMID:
19362379
49.

Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain.

Ahlenius H, Visan V, Kokaia M, Lindvall O, Kokaia Z.

J Neurosci. 2009 Apr 8;29(14):4408-19. doi: 10.1523/JNEUROSCI.6003-08.2009.

50.

Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke.

Carlén M, Meletis K, Göritz C, Darsalia V, Evergren E, Tanigaki K, Amendola M, Barnabé-Heider F, Yeung MS, Naldini L, Honjo T, Kokaia Z, Shupliakov O, Cassidy RM, Lindvall O, Frisén J.

Nat Neurosci. 2009 Mar;12(3):259-67. doi: 10.1038/nn.2268. Epub 2009 Feb 22.

PMID:
19234458

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