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Items: 1 to 50 of 101

1.
2.

BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.

Iguchi T, Aoki K, Ikawa T, Taoka M, Taya C, Yoshitani H, Toma-Hirano M, Koiwai O, Isobe T, Kawamoto H, Masai H, Miyatake S.

J Immunol. 2015 Aug 1;195(3):982-93. doi: 10.4049/jimmunol.1500602. Epub 2015 Jul 1.

3.

Definition of the transcription factor TdIF1 consensus-binding sequence through genomewide mapping of its binding sites.

Koiwai K, Kubota T, Watanabe N, Hori K, Koiwai O, Masai H.

Genes Cells. 2015 Mar;20(3):242-54. doi: 10.1111/gtc.12216. Epub 2015 Jan 26.

4.

Truncated UDP-glucuronosyltransferase (UGT) from a Crigler-Najjar syndrome type II patient colocalizes with intact UGT in the endoplasmic reticulum.

Suzuki M, Hirata M, Takagi M, Watanabe T, Iguchi T, Koiwai K, Maezawa S, Koiwai O.

J Hum Genet. 2014 Mar;59(3):158-62. doi: 10.1038/jhg.2013.138. Epub 2014 Jan 9.

5.

Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.

Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):808-13. doi: 10.1016/j.bbrc.2013.12.052. Epub 2013 Dec 14.

6.

TdIF1 recognizes a specific DNA sequence through its Helix-Turn-Helix and AT-hook motifs to regulate gene transcription.

Kubota T, Koiwai O, Hori K, Watanabe N, Koiwai K.

PLoS One. 2013 Jul 10;8(7):e66710. doi: 10.1371/journal.pone.0066710. Print 2013.

7.

BRCT domain of DNA polymerase μ has DNA-binding activity and promotes the DNA polymerization activity.

Matsumoto T, Go K, Hyodo M, Koiwai K, Maezawa S, Hayano T, Suzuki M, Koiwai O.

Genes Cells. 2012 Sep;17(9):790-806. doi: 10.1111/j.1365-2443.2012.01628.x. Epub 2012 Aug 16.

8.

Ubiquitylation of terminal deoxynucleotidyltransferase inhibits its activity.

Maezawa S, Fukushima R, Matsushita T, Kato T, Takagaki Y, Nishiyama Y, Ando S, Matsumoto T, Kouda K, Hayano T, Suzuki M, Koiwai K, Koiwai O.

PLoS One. 2012;7(7):e39511. doi: 10.1371/journal.pone.0039511. Epub 2012 Jul 11.

9.

Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex.

Nishimoto N, Watanabe M, Watanabe S, Sugimoto N, Yugawa T, Ikura T, Koiwai O, Kiyono T, Fujita M.

J Cell Sci. 2012 Aug 15;125(Pt 16):3870-82. doi: 10.1242/jcs.104349. Epub 2012 May 8.

10.

TdIF2 is a nucleolar protein that promotes rRNA gene promoter activity.

Koiwai K, Noma S, Takahashi Y, Hayano T, Maezawa S, Kouda K, Matsumoto T, Suzuki M, Furuichi M, Koiwai O.

Genes Cells. 2011 Jul;16(7):748-64. doi: 10.1111/j.1365-2443.2011.01524.x. Epub 2011 Jun 13.

11.

TdT interacting factor 1 enhances TdT ubiquitylation through recruitment of BPOZ-2 into nucleus from cytoplasm.

Hayano T, Koiwai K, Ishii H, Maezawa S, Kouda K, Motoyama T, Kubota T, Koiwai O.

Genes Cells. 2009 Dec;14(12):1415-27. doi: 10.1111/j.1365-2443.2009.01358.x. Epub 2009 Nov 20.

12.

BPOZ-2 directly binds to eEF1A1 to promote eEF1A1 ubiquitylation and degradation and prevent translation.

Koiwai K, Maezawa S, Hayano T, Iitsuka M, Koiwai O.

Genes Cells. 2008 Jun;13(6):593-607. doi: 10.1111/j.1365-2443.2008.01191.x. Epub 2008 Mar 4.

13.

Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase.

Maezawa S, Hayano T, Koiwai K, Fukushima R, Kouda K, Kubota T, Koiwai O.

Genes Cells. 2008 May;13(5):439-57. doi: 10.1111/j.1365-2443.2008.01179.x.

14.

Direct binding of ligandin to uridine 5'-diphosphate glucuronosyltransferase 1A1.

Akizawa E, Koiwai K, Hayano T, Maezawa S, Matsushita T, Koiwai O.

Hepatol Res. 2008 Apr;38(4):402-9. Epub 2007 Nov 16.

PMID:
18021224
15.

Cell density-dependent regulation of tumor necrosis factor alpha gene expression in a human hepatoma cell line.

Fukushima S, Kaneko N, Koiwai O, Koike K.

Int J Oncol. 2007 Dec;31(6):1485-90.

PMID:
17982675
16.

Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity.

Kubota T, Maezawa S, Koiwai K, Hayano T, Koiwai O.

Genes Cells. 2007 Aug;12(8):941-59.

17.

Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases.

Ishimaru C, Kuriyama I, Shimazaki N, Koiwai O, Sakaguchi K, Kato I, Yoshida H, Mizushina Y.

Biochem Biophys Res Commun. 2007 Mar 9;354(2):619-25. Epub 2007 Jan 16.

PMID:
17241613
18.

Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation.

Watanabe R, Harada Y, Takeda K, Takahashi J, Ohnuki K, Ogawa S, Ohgai D, Kaibara N, Koiwai O, Tanabe K, Toma H, Sugamura K, Abe R.

J Immunol. 2006 Jul 15;177(2):1085-91.

19.

Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor.

Mizushina Y, Nakanishi R, Kuriyama I, Kamiya K, Satake T, Shimazaki N, Koiwai O, Uchiyama Y, Yonezawa Y, Takemura M, Sakaguchi K, Yoshida H.

J Steroid Biochem Mol Biol. 2006 May;99(2-3):100-7. Epub 2006 Apr 18.

PMID:
16621516
20.

Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.

Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.

Genes Cells. 2006 Mar;11(3):223-35.

21.

5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.

Mizushina Y, Yagita E, Kuramochi K, Kuriyama I, Shimazaki N, Koiwai O, Uchiyama Y, Yomezawa Y, Sugawara F, Kobayashi S, Sakaguchi K, Yoshida H.

Arch Biochem Biophys. 2006 Feb 1;446(1):69-76. Epub 2005 Dec 15.

PMID:
16405901
22.

Direct binding of TReP-132 with TdT results in reduction of TdT activity.

Fujisaki S, Sato A, Toyomoto T, Hayano T, Sugai M, Kubota T, Koiwai O.

Genes Cells. 2006 Jan;11(1):47-57.

23.

Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis.

Mizushina Y, Nakagawa K, Shibata A, Awata Y, Kuriyama I, Shimazaki N, Koiwai O, Uchiyama Y, Sakaguchi K, Miyazawa T, Yoshida H.

Biochem Biophys Res Commun. 2006 Jan 20;339(3):949-55. Epub 2005 Nov 28.

PMID:
16325764
24.

Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.

Mizushina Y, Ishidoh T, Takeuchi T, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1288-95. Epub 2005 Oct 10.

PMID:
16236265
25.

Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin.

Uchiyama Y, Tagami J, Kamisuki S, Kasai N, Oshige M, Chiku H, Ibe S, Koiwai O, Sugawara F, Sakaguchi K.

Biochim Biophys Acta. 2005 Oct 10;1725(3):298-304.

PMID:
16099107
26.

Rb1cc1 is critical for myoblast differentiation through Rb1 regulation.

Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H.

Virchows Arch. 2005 Sep;447(3):643-8. Epub 2005 Jun 21.

PMID:
15968549
27.

DNA polymerase lambda directly binds to proliferating cell nuclear antigen through its confined C-terminal region.

Shimazaki N, Yazaki T, Kubota T, Sato A, Nakamura A, Kurei S, Toji S, Tamai K, Koiwai O.

Genes Cells. 2005 Jul;10(7):705-15.

28.

Functional analyses of mouse ASK, an activation subunit for Cdc7 kinase, using conditional ASK knockout ES cells.

Yamashita N, Kim JM, Koiwai O, Arai K, Masai H.

Genes Cells. 2005 Jun;10(6):551-63.

29.

Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.

Mizushina Y, Kuramochi K, Ikawa H, Kuriyama I, Shimazaki N, Takemura M, Oshige M, Yoshida H, Koiwai O, Sugawara F, Kobayashi S, Sakaguchi K.

Int J Mol Med. 2005 May;15(5):785-93.

PMID:
15806299
30.

UDP-glucuronosyltransferase1A1 directly binds to albumin.

Ohta Y, Fukushima S, Yamashita N, Niimi T, Kubota T, Akizawa E, Koiwai O.

Hepatol Res. 2005 Apr;31(4):241-5.

PMID:
15777743
31.

A biochemically defined system for mammalian nonhomologous DNA end joining.

Ma Y, Lu H, Tippin B, Goodman MF, Shimazaki N, Koiwai O, Hsieh CL, Schwarz K, Lieber MR.

Mol Cell. 2004 Dec 3;16(5):701-13.

32.

Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.

Mizushina Y, Hirota M, Murakami C, Ishidoh T, Kamisuki S, Shimazaki N, Takemura M, Perpelescu M, Suzuki M, Yoshida H, Sugawara F, Koiwai O, Sakaguchi K.

Biochem Pharmacol. 2003 Nov 15;66(10):1935-44.

PMID:
14599551
33.

Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone.

Fujita K, Shimazaki N, Ohta Y, Kubota T, Ibe S, Toji S, Tamai K, Fujisaki S, Hayano T, Koiwai O.

Genes Cells. 2003 Jun;8(6):559-71.

34.

Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos.

Mizushina Y, Murakami C, Takikawa H, Kasai N, Xu X, Mori K, Oshige M, Yamaguchi T, Saneyoshi M, Shimazaki N, Koiwai O, Yoshida H, Sugawara F, Sakaguchi K.

J Biochem. 2003 Apr;133(4):541-52.

35.

A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS).

Harada Y, Ohgai D, Watanabe R, Okano K, Koiwai O, Tanabe K, Toma H, Altman A, Abe R.

J Exp Med. 2003 Jan 20;197(2):257-62.

36.

Human neutrophils isolated from peripheral blood contain Ku protein but not DNA-dependent protein kinase.

Kurosawa A, Shinohara K, Watanabe F, Shimizu-Saito K, Koiwai O, Yamamoto K, Teraoka H.

Int J Biochem Cell Biol. 2003 Jan;35(1):86-94.

PMID:
12467650
37.

Petasiphenol: a DNA polymerase lambda inhibitor.

Mizushina Y, Kamisuki S, Kasai N, Ishidoh T, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K.

Biochemistry. 2002 Dec 10;41(49):14463-71.

PMID:
12463744
38.

A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.

Mizushina Y, Xu X, Asahara H, Takeuchi R, Oshige M, Shimazaki N, Takemura M, Yamaguchi T, Kuroda K, Linn S, Yoshida H, Koiwai O, Saneyoshi M, Sugawara F, Sakaguchi K.

Biochem J. 2003 Feb 15;370(Pt 1):299-305.

39.

Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme.

Shimazaki N, Yoshida K, Kobayashi T, Toji S, Tamai K, Koiwai O.

Genes Cells. 2002 Jul;7(7):639-51.

40.

Identification and characterization of the UL56 gene product of herpes simplex virus type 2.

Koshizuka T, Goshima F, Takakuwa H, Nozawa N, Daikoku T, Koiwai O, Nishiyama Y.

J Virol. 2002 Jul;76(13):6718-28.

41.

[Expression and function of terminal deoxynucleotidyl-transferase and discovery of novel DNA polymerase mu].

Shimazaki N, Fujita K, Koiwai O.

Seikagaku. 2002 Mar;74(3):227-32. Review. Japanese. No abstract available.

PMID:
11974916
42.

A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.

Mizushina Y, Kamisuki S, Kasai N, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Matsukage A, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K.

J Biol Chem. 2002 Jan 4;277(1):630-8. Epub 2001 Oct 24.

43.

Terminal deoxynucleotidyltransferase is negatively regulated by direct interaction with proliferating cell nuclear antigen.

Ibe S, Fujita K, Toyomoto T, Shimazaki N, Kaneko R, Tanabe A, Takebe I, Kuroda S, Kobayashi T, Toji S, Tamai K, Yamamoto H, Koiwai O.

Genes Cells. 2001 Sep;6(9):815-24.

44.

Drosophila mitochondrial transcription factor A: characterization of its cDNA and expression pattern during development.

Takata K, Yoshida H, Hirose F, Yamaguchi M, Kai M, Oshige M, Sakimoto I, Koiwai O, Sakaguchi K.

Biochem Biophys Res Commun. 2001 Sep 21;287(2):474-83.

PMID:
11554753
45.

Cytological examination of rat amniotic epithelial cells and cell transplantation to the liver.

Nakajima T, Enosawa S, Mitani T, Li XK, Suzuki S, Amemiya H, Koiwai O, Sakuragawa N.

Cell Transplant. 2001;10(4-5):423-7.

PMID:
11549066
46.

Terminal deoxynucleotidyltransferase directly interacts with a novel nuclear protein that is homologous to p65.

Yamashita N, Shimazaki N, Ibe S, Kaneko R, Tanabe A, Toyomoto T, Fujita K, Hasegawa T, Toji S, Tamai K, Yamamoto H, Koiwai O.

Genes Cells. 2001 Jul;6(7):641-52.

47.

Strong, long-term transgene expression in rat liver using chicken beta-actin promoter associated with cytomegalovirus immediate-early enhancer (CAG promoter).

Kosuga M, Enosawa S, Li XK, Suzuki S, Matsuo N, Yamada M, Roy-Chowdhury J, Koiwai O, Okuyama T.

Cell Transplant. 2000 Sep-Oct;9(5):675-80.

PMID:
11144964
48.

Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.

Harada Y, Tanabe E, Watanabe R, Weiss BD, Matsumoto A, Ariga H, Koiwai O, Fukui Y, Kubo M, June CH, Abe R.

J Biol Chem. 2001 Mar 23;276(12):9003-8. Epub 2000 Dec 11.

49.

Molecular cloning and expression during development of the Drosophila gene for the catalytic subunit of DNA polymerase epsilon.

Oshige M, Yoshida H, Hirose F, Takata KI, Inoue Y, Aoyagi N, Yamaguchi M, Koiwai O, Matsukage A, Sakaguchi K.

Gene. 2000 Oct 3;256(1-2):93-100.

PMID:
11054539
50.

The UL34 gene product of herpes simplex virus type 2 is a tail-anchored type II membrane protein that is significant for virus envelopment.

Shiba C, Daikoku T, Goshima F, Takakuwa H, Yamauchi Y, Koiwai O, Nishiyama Y.

J Gen Virol. 2000 Oct;81(Pt 10):2397-405.

PMID:
10993927

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