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Items: 1 to 50 of 102

1.

Regulation of cell adhesion: a collaborative effort of integrins, their ligands, cytoplasmic actors, and phosphorylation.

Gahmberg CG, Grönholm M, Madhavan S, Jahan F, Mikkola E, Viazmina L, Koivunen E.

Q Rev Biophys. 2019 Nov 11;52:e10. doi: 10.1017/S0033583519000088.

PMID:
31709962
2.

Internet use for family carers of people with intellectual disabilities: A literature review and thematic synthesis.

Caton S, Koivunen ER, Allison C.

J Intellect Disabil. 2019 Sep;23(3):446-468. doi: 10.1177/1744629519874214.

PMID:
31496385
3.

Associations Between Drosophila suzukii (Diptera: Drosophilidae) and Fungi in Raspberries.

Lewis MT, Koivunen EE, Swett CL, Hamby KA.

Environ Entomol. 2019 Feb 13;48(1):68-79. doi: 10.1093/ee/nvy167.

PMID:
30520973
4.

Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.

Staquicini DI, D'Angelo S, Ferrara F, Karjalainen K, Sharma G, Smith TL, Tarleton CA, Jaalouk DE, Kuniyasu A, Baze WB, Chaffee BK, Hanley PW, Barnhart KF, Koivunen E, Marchiò S, Sidman RL, Cortes JE, Kantarjian HM, Arap W, Pasqualini R.

Pharmacogenomics J. 2018 May 22;18(3):436-443. doi: 10.1038/tpj.2017.46. Epub 2017 Dec 5.

5.

Effects of plant species, stage of maturity, and level of formic acid addition on lipolysis, lipid content, and fatty acid composition during ensiling.

Koivunen E, Jaakkola S, Heikkilä T, Lampi AM, Halmemies-Beauchet-Filleau A, Lee MR, Winters AL, Shingfield KJ, Vanhatalo A.

J Anim Sci. 2015 Sep;93(9):4408-23. doi: 10.2527/jas.2014-8813.

PMID:
26440341
6.

Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens.

Karjalainen K, Jaalouk DE, Bueso-Ramos C, Bover L, Sun Y, Kuniyasu A, Driessen WH, Cardó-Vila M, Rietz C, Zurita AJ, O'Brien S, Kantarjian HM, Cortes JE, Calin GA, Koivunen E, Arap W, Pasqualini R.

Clin Cancer Res. 2015 Jul 1;21(13):3041-51. doi: 10.1158/1078-0432.CCR-13-3059. Epub 2015 Mar 16.

7.

Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia.

Karjalainen K, Pasqualini R, Cortes JE, Kornblau SM, Lichtiger B, O'Brien S, Kantarjian HM, Sidman RL, Arap W, Koivunen E.

Cancer. 2014 Feb 15;120(4):589-602. doi: 10.1002/cncr.28419. Epub 2013 Oct 25.

8.

In vivo targeting of activated leukocytes by a β2-integrin binding peptide.

Ranta TM, Suojanen J, Peñate-Medina O, Will O, Tower RJ, Glüer C, Kairemo K, Gahmberg CG, Koivunen E, Sorsa T, Saris PE, Reunanen J.

Mol Diagn Ther. 2014 Feb;18(1):39-44. doi: 10.1007/s40291-013-0052-5.

PMID:
23982749
9.

Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells.

Rangel R, Guzman-Rojas L, le Roux LG, Staquicini FI, Hosoya H, Barbu EM, Ozawa MG, Nie J, Dunner K Jr, Langley RR, Sage EH, Koivunen E, Gelovani JG, Lobb RR, Sidman RL, Pasqualini R, Arap W.

Nat Commun. 2012 Apr 17;3:788. doi: 10.1038/ncomms1773.

10.

Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment.

Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1637-42. doi: 10.1073/pnas.1120790109. Epub 2012 Jan 17.

11.

Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients.

Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18637-42. doi: 10.1073/pnas.1114503108. Epub 2011 Nov 2.

12.

Targeting neuropilin-1 in human leukemia and lymphoma.

Karjalainen K, Jaalouk DE, Bueso-Ramos CE, Zurita AJ, Kuniyasu A, Eckhardt BL, Marini FC, Lichtiger B, O'Brien S, Kantarjian HM, Cortes JE, Koivunen E, Arap W, Pasqualini R.

Blood. 2011 Jan 20;117(3):920-7. doi: 10.1182/blood-2010-05-282921. Epub 2010 Nov 9.

13.

A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.

Reunanen J, Ranta TM, Peñate-Medina O, Suojanen J, Sorsa T, Salo T, Koivunen E, Saris PE.

Protein Expr Purif. 2010 Aug;72(2):234-7. doi: 10.1016/j.pep.2010.03.023. Epub 2010 Apr 3.

PMID:
20371289
14.

Identification of novel peptide inhibitors for human trypsins.

Wu P, Weisell J, Pakkala M, Peräkylä M, Zhu L, Koistinen R, Koivunen E, Stenman UH, Närvänen A, Koistinen H.

Biol Chem. 2010 Feb-Mar;391(2-3):283-93. doi: 10.1515/BC.2010.030.

PMID:
20128688
15.

Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate.

Kivi E, Elima K, Aalto K, Nymalm Y, Auvinen K, Koivunen E, Otto DM, Crocker PR, Salminen TA, Salmi M, Jalkanen S.

Blood. 2009 Dec 17;114(26):5385-92. doi: 10.1182/blood-2009-04-219253. Epub 2009 Oct 27.

16.

A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth.

Suojanen J, Salo T, Koivunen E, Sorsa T, Pirilä E.

Cancer Biol Ther. 2009 Dec;8(24):2362-70. Epub 2009 Dec 19.

PMID:
19855192
17.

Role of leukemia cell invadosome in extramedullary infiltration.

Stefanidakis M, Karjalainen K, Jaalouk DE, Gahmberg CG, O'Brien S, Pasqualini R, Arap W, Koivunen E.

Blood. 2009 Oct 1;114(14):3008-17. doi: 10.1182/blood-2008-04-148643. Epub 2009 Jul 27.

18.

An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.

Mintz PJ, Cardó-Vila M, Ozawa MG, Hajitou A, Rangel R, Guzman-Rojas L, Christianson DR, Arap MA, Giordano RJ, Souza GR, Easley J, Salameh A, Oliviero S, Brentani RR, Koivunen E, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2182-7. doi: 10.1073/pnas.0807543105. Epub 2009 Jan 23.

19.

Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells.

Nishimura S, Takahashi S, Kamikatahira H, Kuroki Y, Jaalouk DE, O'Brien S, Koivunen E, Arap W, Pasqualini R, Nakayama H, Kuniyasu A.

J Biol Chem. 2008 Apr 25;283(17):11752-62. doi: 10.1074/jbc.M708849200. Epub 2008 Feb 21.

20.

AlphaMbeta2 integrin modulator exerts antitumor activity in vivo.

Suojanen J, Salo T, Sorsa T, Koivunen E.

Anticancer Res. 2007 Nov-Dec;27(6B):3775-81.

21.

Blood stem cell mobilization and collection in patients with chronic lymphocytic leukaemia: a nationwide analysis.

Jantunen E, Itälä M, Siitonen T, Kuittinen T, Heiskanen J, Koivunen E, Juvonen E, Silvennoinen R, Nousiainen T, Koistinen P, Volin L, Remes K.

Bone Marrow Transplant. 2008 Feb;41(3):239-44. Epub 2007 Oct 29.

PMID:
17968327
22.

Long-term outcome of intensive chemotherapy for adults with de novo acute myeloid leukaemia (AML): the nationwide AML-92 study by the Finnish Leukaemia Group.

Koistinen P, Räty R, Itälä M, Jantunen E, Koivunen E, Nousiainen T, Pelliniemi TT, Remes K, Ruutu T, Savolainen ER, Siitonen T, Silvennoinen R, Volin L, Elonen E; Finnish Leukaemia Group.

Eur J Haematol. 2007 Jun;78(6):477-86. Epub 2007 Mar 28.

PMID:
17391337
23.

Late non-relapse mortality among adult autologous stem cell transplant recipients: a nation-wide analysis of 1,482 patients transplanted in 1990-2003.

Jantunen E, Itälä M, Siitonen T, Koivunen E, Leppä S, Juvonen E, Kuittinen O, Lehtinen T, Koistinen P, Nyman H, Nousiainen T, Volin L, Remes K.

Eur J Haematol. 2006 Aug;77(2):114-9.

PMID:
16856906
24.

Autologous stem cell transplantation in patients with chronic lymphocytic leukaemia: the Finnish experience.

Jantunen E, Itälä M, Siitonen T, Juvonen E, Koivunen E, Koistinen P, Volin L, Remes K, Nousiainen T.

Bone Marrow Transplant. 2006 Jun;37(12):1093-8. Epub 2006 May 8.

PMID:
16699533
25.
26.

Novel peptide inhibitors of human kallikrein 2.

Hekim C, Leinonen J, Närvänen A, Koistinen H, Zhu L, Koivunen E, Väisänen V, Stenman UH.

J Biol Chem. 2006 May 5;281(18):12555-60. Epub 2006 Mar 9.

27.

Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment.

Björklund M, Aitio O, Stefanidakis M, Suojanen J, Salo T, Sorsa T, Koivunen E.

Biochemistry. 2006 Mar 7;45(9):2862-71.

PMID:
16503641
28.

Early treatment-related mortality in adult autologous stem cell transplant recipients: a nation-wide survey of 1482 transplanted patients.

Jantunen E, Itälä M, Lehtinen T, Kuittinen O, Koivunen E, Leppä S, Juvonen E, Koistinen P, Wiklund T, Nousiainen T, Remes K, Volin L.

Eur J Haematol. 2006 Mar;76(3):245-50. Epub 2006 Jan 12.

PMID:
16412136
29.

Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides.

Heikkilä P, Suojanen J, Pirilä E, Väänänen A, Koivunen E, Sorsa T, Salo T.

Int J Cancer. 2006 May 1;118(9):2202-9.

30.

A tripeptide mimetic of von Willebrand factor residues 981-983 enhances platelet adhesion to fibrinogen by signaling through integrin alpha(IIb)beta3.

Litjens PE, Van Willigen G, Weeterings C, Ijsseldijk MJ, Van Lier M, Koivunen E, Gahmberg CG, Akkerman JW.

J Thromb Haemost. 2005 Jun;3(6):1274-83.

31.

Gelatinase-mediated migration and invasion of cancer cells.

Björklund M, Koivunen E.

Biochim Biophys Acta. 2005 May 25;1755(1):37-69. Epub 2005 Apr 12. Review.

PMID:
15907591
32.

Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide.

Medina OP, Kairemo K, Valtanen H, Kangasniemi A, Kaukinen S, Ahonen I, Permi P, Annila A, Sneck M, Holopainen JM, Karonen SL, Kinnunen PK, Koivunen E.

Anticancer Res. 2005 Jan-Feb;25(1A):33-42.

33.

Autologous stem cell transplantation in patients with high-risk plasmacytoma.

Jantunen E, Koivunen E, Putkonen M, Siitonen T, Juvonen E, Nousiainen T.

Eur J Haematol. 2005 May;74(5):402-6.

PMID:
15813914
34.

Autologous stem cell transplantation in patients with primary amyloidosis: a nation-wide survey.

Jantunen E, Siitonen T, Putkonen M, Koivunen E, Juvonen E, Nousiainen T, Koistinen P.

Leuk Lymphoma. 2004 Dec;45(12):2485-9.

PMID:
15621765
35.

Peptide-mediated delivery of therapeutic and imaging agents into mammalian cells.

Stefanidakis M, Koivunen E.

Curr Pharm Des. 2004;10(24):3033-44. Review.

PMID:
15379666
36.

Invasive fungal infections in autologous stem cell transplant recipients: a nation-wide study of 1188 transplanted patients.

Jantunen E, Salonen J, Juvonen E, Koivunen E, Siitonen T, Lehtinen T, Kuittinen O, Leppä S, Anttila VJ, Itälä M, Wiklund T, Remes K, Nousiainen T.

Eur J Haematol. 2004 Sep;73(3):174-8.

PMID:
15287914
37.

Intracellular and cell surface localization of a complex between alphaMbeta2 integrin and promatrix metalloproteinase-9 progelatinase in neutrophils.

Stefanidakis M, Ruohtula T, Borregaard N, Gahmberg CG, Koivunen E.

J Immunol. 2004 Jun 1;172(11):7060-8.

38.

Peptide inhibition of catalytic and noncatalytic activities of matrix metalloproteinase-9 blocks tumor cell migration and invasion.

Björklund M, Heikkilä P, Koivunen E.

J Biol Chem. 2004 Jul 9;279(28):29589-97. Epub 2004 Apr 30.

39.

Oral treatment of acute myeloid leukaemia with etoposide, thioguanine, and idarubicin (ETI) in elderly patients: a prospective randomised comparison with intravenous cytarabine, idarubicin, and thioguanine in the second and third treatment cycle.

Ruutu T, Koivunen E, Nousiainen T, Pelliniemi TT, Almqvist A, Anttila P, Jantunen E, Koistinen P, Koponen A, Mikkola M, Oksanen K, Pulli T, Remes K, Sarkkinen R, Silvennoinen R, Timonen T, Vanhatalo S, Elonen E; Finnish Leukaemia Group.

Eur J Haematol. 2004 Jan;72(1):38-44.

PMID:
14962261
40.

Identification of a negatively charged peptide motif within the catalytic domain of progelatinases that mediates binding to leukocyte beta 2 integrins.

Stefanidakis M, Bjorklund M, Ihanus E, Gahmberg CG, Koivunen E.

J Biol Chem. 2003 Sep 5;278(36):34674-84. Epub 2003 Jun 24.

41.

Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide.

Björklund M, Valtanen H, Savilahti H, Koivunen E.

Comb Chem High Throughput Screen. 2003 Feb;6(1):29-35.

PMID:
12570750
42.

Steps toward mapping the human vasculature by phage display.

Arap W, Kolonin MG, Trepel M, Lahdenranta J, Cardó-Vila M, Giordano RJ, Mintz PJ, Ardelt PU, Yao VJ, Vidal CI, Chen L, Flamm A, Valtanen H, Weavind LM, Hicks ME, Pollock RE, Botz GH, Bucana CD, Koivunen E, Cahill D, Troncoso P, Baggerly KA, Pentz RD, Do KA, Logothetis CJ, Pasqualini R.

Nat Med. 2002 Feb;8(2):121-7.

PMID:
11821895
43.

In vivo localization of gelatinases (MMP-2 and -9) by in situ zymography with a selective gelatinase inhibitor.

Pirilä E, Maisi P, Salo T, Koivunen E, Sorsa T.

Biochem Biophys Res Commun. 2001 Sep 28;287(3):766-74.

PMID:
11563862
44.

Inhibition of beta(2) integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides.

Koivunen E, Ranta TM, Annila A, Taube S, Uppala A, Jokinen M, van Willigen G, Ihanus E, Gahmberg CG.

J Cell Biol. 2001 May 28;153(5):905-16.

45.

Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro.

Medina OP, Söderlund T, Laakkonen LJ, Tuominen EK, Koivunen E, Kinnunen PK.

Cancer Res. 2001 May 15;61(10):3978-85.

46.

The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.

Paju A, Sorsa T, Tervahartiala T, Koivunen E, Haglund C, Leminen A, Wahlström T, Salo T, Stenman UH.

Br J Cancer. 2001 May 18;84(10):1363-71.

47.

Development of novel peptide ligands modulating the enzyme activity of prostate-specific antigen.

Leinonen J, Wu P, Koivunen E, Närvänen A, Stenman UH.

Scand J Clin Lab Invest Suppl. 2000;233:59-64.

PMID:
11317943
48.

Echocardiographic Imaging of Right Ventricular Outflow Obstruction During Chemotherapy of Mediastinal Lymphoma.

Laine OK, Groundstroem KW, Koivunen EA.

Echocardiography. 1999 Nov;16(8):823-825.

PMID:
11175227
49.

Echocardiographic Imaging of Right Ventricular Outflow Obstruction During Chemotherapy of Mediastinal Lymphoma.

Laine OK, Groundstroem KW, Koivunen EA.

Echocardiography. 1999 Oct;16:1-2.

PMID:
11175201
50.

Targeting of phage display vectors to mammalian cells.

Uppala A, Koivunen E.

Comb Chem High Throughput Screen. 2000 Oct;3(5):373-92. Review.

PMID:
11032955

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