Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 195

1.

Facile target validation in an animal model with intracellularly expressed monobodies.

Gupta A, Xu J, Lee S, Tsai ST, Zhou B, Kurosawa K, Werner MS, Koide A, Ruthenburg AJ, Dou Y, Koide S.

Nat Chem Biol. 2018 Jul 16. doi: 10.1038/s41589-018-0099-z. [Epub ahead of print]

PMID:
30013062
2.

A CLC-type F-/H+ antiporter in ion-swapped conformations.

Last NB, Stockbridge RB, Wilson AE, Shane T, Kolmakova-Partensky L, Koide A, Koide S, Miller C.

Nat Struct Mol Biol. 2018 Jul;25(7):601-606. doi: 10.1038/s41594-018-0082-0. Epub 2018 Jun 25.

PMID:
29941917
3.

Precision imaging of 4.4 MeV gamma rays using a 3-D position sensitive Compton camera.

Koide A, Kataoka J, Masuda T, Mochizuki S, Taya T, Sueoka K, Tagawa L, Fujieda K, Maruhashi T, Kurihara T, Inaniwa T.

Sci Rep. 2018 May 25;8(1):8116. doi: 10.1038/s41598-018-26591-2.

4.

Monobody-Mediated Alteration of Lipase Substrate Specificity.

Tanaka SI, Takahashi T, Koide A, Iwamoto R, Koikeda S, Koide S.

ACS Chem Biol. 2018 Jun 15;13(6):1487-1492. doi: 10.1021/acschembio.8b00384. Epub 2018 May 18.

PMID:
29757606
5.

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.

Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ.

Elife. 2018 Mar 29;7. pii: e33572. doi: 10.7554/eLife.33572.

6.

Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.

Diver MM, Pedi L, Koide A, Koide S, Long SB.

Nature. 2018 Jan 25;553(7689):526-529. doi: 10.1038/nature25439. Epub 2018 Jan 17.

7.

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.

Reckel S, Gehin C, Tardivon D, Georgeon S, Kükenshöner T, Löhr F, Koide A, Buchner L, Panjkovich A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O.

Nat Commun. 2017 Dec 13;8(1):2101. doi: 10.1038/s41467-017-02313-6.

8.

A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis.

Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, Ranjan R, Dogra S, Koide A, Yadav PN, Sidhu SS, Koide S, Shukla AK.

Nat Nanotechnol. 2017 Dec;12(12):1190-1198. doi: 10.1038/nnano.2017.188. Epub 2017 Oct 2.

9.

Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region.

Salzman GS, Zhang S, Gupta A, Koide A, Koide S, Araç D.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10095-10100. doi: 10.1073/pnas.1708810114. Epub 2017 Sep 5.

10.

Temporal expression of chitinase-like 3 in wounded murine skin.

Murase T, Yamamoto T, Koide A, Yagi Y, Kagawa S, Tsuruya S, Abe Y, Umehara T, Ikematsu K.

Int J Legal Med. 2017 Nov;131(6):1623-1631. doi: 10.1007/s00414-017-1658-7. Epub 2017 Aug 6.

PMID:
28780759
11.

Targeting the α4-α5 interface of RAS results in multiple levels of inhibition.

Spencer-Smith R, Li L, Prasad S, Koide A, Koide S, O'Bryan JP.

Small GTPases. 2017 Jul 10:1-10. doi: 10.1080/21541248.2017.1333188. [Epub ahead of print]

PMID:
28692342
12.

Capturing local structure modulations of photoexcited BiVO4 by ultrafast transient XAFS.

Uemura Y, Kido D, Koide A, Wakisaka Y, Niwa Y, Nozawa S, Ichiyanagi K, Fukaya R, Adachi SI, Katayama T, Togashi T, Owada S, Yabashi M, Hatada K, Iwase A, Kudo A, Takakusagi S, Yokoyama T, Asakura K.

Chem Commun (Camb). 2017 Jun 29;53(53):7314-7317. doi: 10.1039/c7cc02201h.

PMID:
28480915
13.

Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody.

Rizk SS, Mukherjee S, Koide A, Koide S, Kossiakoff AA.

Sci Rep. 2017 Apr 3;7(1):556. doi: 10.1038/s41598-017-00728-1.

14.

Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.

Kükenshöner T, Schmit NE, Bouda E, Sha F, Pojer F, Koide A, Seeliger M, Koide S, Hantschel O.

J Mol Biol. 2017 May 5;429(9):1364-1380. doi: 10.1016/j.jmb.2017.03.023. Epub 2017 Mar 25.

15.

sNASP and ASF1A function through both competitive and compatible modes of histone binding.

Bowman A, Koide A, Goodman JS, Colling ME, Zinne D, Koide S, Ladurner AG.

Nucleic Acids Res. 2017 Jan 25;45(2):643-656. doi: 10.1093/nar/gkw892. Epub 2016 Oct 5.

16.

Inhibition of RAS function through targeting an allosteric regulatory site.

Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP.

Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7.

17.

Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.

Salzman GS, Ackerman SD, Ding C, Koide A, Leon K, Luo R, Stoveken HM, Fernandez CG, Tall GG, Piao X, Monk KR, Koide S, Araç D.

Neuron. 2016 Sep 21;91(6):1292-1304. doi: 10.1016/j.neuron.2016.08.022.

18.

Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.

Shao Y, Huang H, Qin D, Li NS, Koide A, Staley JP, Koide S, Kossiakoff AA, Piccirilli JA.

J Mol Biol. 2016 Oct 9;428(20):4100-4114. doi: 10.1016/j.jmb.2016.08.029. Epub 2016 Sep 2.

19.

[Regulatory Science in the Review of Drugs and Medical Devices].

Koide A.

Yakugaku Zasshi. 2016;136(4):557-62. doi: 10.1248/yakushi.15-00224-6. Review. Japanese.

20.

Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.

Wojcik J, Lamontanara AJ, Grabe G, Koide A, Akin L, Gerig B, Hantschel O, Koide S.

J Biol Chem. 2016 Apr 15;291(16):8836-47. doi: 10.1074/jbc.M115.707901. Epub 2016 Feb 24.

21.

Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.

Hattori T, Lai D, Dementieva IS, Montaño SP, Kurosawa K, Zheng Y, Akin LR, Świst-Rosowska KM, Grzybowski AT, Koide A, Krajewski K, Strahl BD, Kelleher NL, Ruthenburg AJ, Koide S.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2092-7. doi: 10.1073/pnas.1522691113. Epub 2016 Feb 9.

22.

ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation.

Nady N, Gupta A, Ma Z, Swigut T, Koide A, Koide S, Wysocka J.

Elife. 2015 Nov 2;4:e10150. doi: 10.7554/eLife.10150.

23.

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.

Zhong N, Loppnau P, Seitova A, Ravichandran M, Fenner M, Jain H, Bhattacharya A, Hutchinson A, Paduch M, Lu V, Olszewski M, Kossiakoff AA, Dowdell E, Koide A, Koide S, Huang H, Nadeem V, Sidhu SS, Greenblatt JF, Marcon E, Arrowsmith CH, Edwards AM, Gräslund S.

PLoS One. 2015 Oct 5;10(10):e0139695. doi: 10.1371/journal.pone.0139695. eCollection 2015.

24.

Crystal structures of a double-barrelled fluoride ion channel.

Stockbridge RB, Kolmakova-Partensky L, Shane T, Koide A, Koide S, Miller C, Newstead S.

Nature. 2015 Sep 24;525(7570):548-51. doi: 10.1038/nature14981. Epub 2015 Sep 7.

25.

Monobody-mediated alteration of enzyme specificity.

Tanaka S, Takahashi T, Koide A, Ishihara S, Koikeda S, Koide S.

Nat Chem Biol. 2015 Oct;11(10):762-4. doi: 10.1038/nchembio.1896. Epub 2015 Aug 31.

26.

Architecture of the fungal nuclear pore inner ring complex.

Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, Mayo DJ, Perriches T, Rundlet EJ, Jeon YE, Collins LN, Huber FM, Lin DH, Paduch M, Koide A, Lu V, Fischer J, Hurt E, Koide S, Kossiakoff AA, Hoelz A.

Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176. Epub 2015 Aug 27.

27.

Childhood-Onset Progressive Dystonia With Mitochondrial DNA G14459A Mutation: Efficacy of Long-Term Sodium Succinate Treatment.

Koide A, Ozawa H, Kubota M, Goto Y.

Child Neurol Open. 2014 Nov 10;1(1):2329048X14550677. doi: 10.1177/2329048X14550677. eCollection 2014 Jul-Sep.

28.

A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of γ-secretase.

Zhang X, Hoey R, Koide A, Dolios G, Paduch M, Nguyen P, Wu X, Li Y, Wagner SL, Wang R, Koide S, Sisodia SS.

J Biol Chem. 2014 Dec 12;289(50):34851-61. doi: 10.1074/jbc.M114.609636. Epub 2014 Oct 28.

29.

Proof of dual-topology architecture of Fluc F- channels with monobody blockers.

Stockbridge RB, Koide A, Miller C, Koide S.

Nat Commun. 2014 Oct 7;5:5120. doi: 10.1038/ncomms6120.

30.

Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.

Yasui N, Findlay GM, Gish GD, Hsiung MS, Huang J, Tucholska M, Taylor L, Smith L, Boldridge WC, Koide A, Pawson T, Koide S.

Mol Cell. 2014 Jun 19;54(6):1034-41. doi: 10.1016/j.molcel.2014.05.002. Epub 2014 Jun 5.

31.

Submucosal tumor-like appendiceal intussusception as a result of fecalith.

Meguro Y, Koide A, Tabuchi T.

Dig Endosc. 2014 Jul;26(4):603. doi: 10.1111/den.12297. Epub 2014 Apr 3. No abstract available.

PMID:
24698365
32.

Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.

Sha F, Gencer EB, Georgeon S, Koide A, Yasui N, Koide S, Hantschel O.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14924-9. doi: 10.1073/pnas.1303640110. Epub 2013 Aug 26.

33.

Recombinant antibodies to histone post-translational modifications.

Hattori T, Taft JM, Swist KM, Luo H, Witt H, Slattery M, Koide A, Ruthenburg AJ, Krajewski K, Strahl BD, White KP, Farnham PJ, Zhao Y, Koide S.

Nat Methods. 2013 Oct;10(10):992-5. doi: 10.1038/nmeth.2605. Epub 2013 Aug 18.

34.

Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.

McCord LA, Liang WG, Dowdell E, Kalas V, Hoey RJ, Koide A, Koide S, Tang WJ.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13827-32. doi: 10.1073/pnas.1304575110. Epub 2013 Aug 6.

35.

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.

Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ.

Nature. 2013 May 2;497(7447):137-41. doi: 10.1038/nature12120. Epub 2013 Apr 21.

36.

Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.

Lu M, Symersky J, Radchenko M, Koide A, Guo Y, Nie R, Koide S.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2099-104. doi: 10.1073/pnas.1219901110. Epub 2013 Jan 22.

37.

The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus.

Tatematsu K, Koide A, Morimura K, Fukushima S, Mori Y.

Mutagenesis. 2013 Mar;28(2):161-9. doi: 10.1093/mutage/ges066. Epub 2013 Jan 15.

PMID:
23325793
38.

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states.

Paduch M, Koide A, Uysal S, Rizk SS, Koide S, Kossiakoff AA.

Methods. 2013 Mar 15;60(1):3-14. doi: 10.1016/j.ymeth.2012.12.010. Epub 2012 Dec 29.

39.

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies.

Persson H, Ye W, Wernimont A, Adams JJ, Koide A, Koide S, Lam R, Sidhu SS.

J Mol Biol. 2013 Feb 22;425(4):803-11. doi: 10.1016/j.jmb.2012.11.037. Epub 2012 Dec 3.

40.

Broad ranges of affinity and specificity of anti-histone antibodies revealed by a quantitative peptide immunoprecipitation assay.

Nishikori S, Hattori T, Fuchs SM, Yasui N, Wojcik J, Koide A, Strahl BD, Koide S.

J Mol Biol. 2012 Dec 14;424(5):391-9. doi: 10.1016/j.jmb.2012.09.022. Epub 2012 Oct 2.

41.

Whole exome sequencing identifies KCNQ2 mutations in Ohtahara syndrome.

Saitsu H, Kato M, Koide A, Goto T, Fujita T, Nishiyama K, Tsurusaki Y, Doi H, Miyake N, Hayasaka K, Matsumoto N.

Ann Neurol. 2012 Aug;72(2):298-300. doi: 10.1002/ana.23620. No abstract available.

PMID:
22926866
42.

T cell receptor-like recognition of tumor in vivo by synthetic antibody fragment.

Miller KR, Koide A, Leung B, Fitzsimmons J, Yoder B, Yuan H, Jay M, Sidhu SS, Koide S, Collins EJ.

PLoS One. 2012;7(8):e43746. doi: 10.1371/journal.pone.0043746. Epub 2012 Aug 20.

43.

Affinity maturation of single-domain antibodies by yeast surface display.

Koide A, Koide S.

Methods Mol Biol. 2012;911:431-43. doi: 10.1007/978-1-61779-968-6_26.

PMID:
22886267
44.

Taste masking of propiverine hydrochloride by conversion to its free base.

Ogata T, Koide A, Kinoshita M, Ozeki T.

Chem Pharm Bull (Tokyo). 2012;60(8):976-84.

45.

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies.

Zhang X, Hoey RJ, Lin G, Koide A, Leung B, Ahn K, Dolios G, Paduch M, Ikeuchi T, Wang R, Li YM, Koide S, Sisodia SS.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8534-9. doi: 10.1073/pnas.1202691109. Epub 2012 May 14.

46.

Anti-obesity role of adzuki bean extract containing polyphenols: in vivo and in vitro effects.

Kitano-Okada T, Ito A, Koide A, Nakamura Y, Han KH, Shimada K, Sasaki K, Ohba K, Sibayama S, Fukushima M.

J Sci Food Agric. 2012 Oct;92(13):2644-51. doi: 10.1002/jsfa.5680. Epub 2012 Apr 11.

PMID:
22495778
47.

Target-binding proteins based on the 10th human fibronectin type III domain (¹⁰Fn3).

Koide S, Koide A, Lipovšek D.

Methods Enzymol. 2012;503:135-56. doi: 10.1016/B978-0-12-396962-0.00006-9.

PMID:
22230568
48.

Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.

Koide A, Wojcik J, Gilbreth RN, Hoey RJ, Koide S.

J Mol Biol. 2012 Jan 13;415(2):393-405. doi: 10.1016/j.jmb.2011.12.019. Epub 2011 Dec 16.

49.

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Grebien F, Hantschel O, Wojcik J, Kaupe I, Kovacic B, Wyrzucki AM, Gish GD, Cerny-Reiterer S, Koide A, Beug H, Pawson T, Valent P, Koide S, Superti-Furga G.

Cell. 2011 Oct 14;147(2):306-19. doi: 10.1016/j.cell.2011.08.046.

50.

Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design.

Gilbreth RN, Truong K, Madu I, Koide A, Wojcik JB, Li NS, Piccirilli JA, Chen Y, Koide S.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7751-6. doi: 10.1073/pnas.1102294108. Epub 2011 Apr 25.

Supplemental Content

Support Center