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Items: 1 to 50 of 94

1.

The exploration of population pharmacokinetic model for meropenem in augmented renal clearance and investigation of optimum setting of dose.

Tamatsukuri T, Ohbayashi M, Kohyama N, Kobayashi Y, Yamamoto T, Fukuda K, Nakamura S, Miyake Y, Dohi K, Kogo M.

J Infect Chemother. 2018 Oct;24(10):834-840. doi: 10.1016/j.jiac.2018.07.007. Epub 2018 Aug 4.

PMID:
30087007
2.

Flavonoid compounds related to seed coat color of wheat.

Kohyama N, Chono M, Nakagawa H, Matsuo Y, Ono H, Matsunaka H.

Biosci Biotechnol Biochem. 2017 Nov;81(11):2112-2118. doi: 10.1080/09168451.2017.1373589. Epub 2017 Sep 22.

PMID:
28934913
3.

Effects of high β-glucan barley on visceral fat obesity in Japanese individuals: A randomized, double-blind study.

Aoe S, Ichinose Y, Kohyama N, Komae K, Takahashi A, Abe D, Yoshioka T, Yanagisawa T.

Nutrition. 2017 Oct;42:1-6. doi: 10.1016/j.nut.2017.05.002. Epub 2017 May 15.

PMID:
28870472
4.

Lung cancer in a patient with predominantly short tremolite fibers in his lung.

Kohyama N, Fujiki M, Kishimoto T, Morinaga K.

Am J Ind Med. 2017 Sep;60(9):831-838. doi: 10.1002/ajim.22748. Epub 2017 Jul 26.

PMID:
28744908
5.

The pharmacokinetics of mianserin suppositories for rectal administration in dogs and healthy volunteers: a pilot study.

Nawata S, Kohyama N, Uchida N, Numazawa S, Ohbayashi M, Kobayashi Y, Iwata M, Nakajima T, Saito H, Izuka A, Yamamoto T.

J Pharm Health Care Sci. 2016 May 17;2:12. doi: 10.1186/s40780-016-0046-7. eCollection 2016.

6.

Size- and type-specific exposure assessment of an asbestos products factory in China.

Courtice MN, Berman DW, Yano E, Kohyama N, Wang X.

J Expo Sci Environ Epidemiol. 2016 Jan-Feb;26(1):63-9. doi: 10.1038/jes.2015.46. Epub 2015 Aug 5.

PMID:
26242170
7.

Significant relationship between the extent of pleural plaques and pulmonary asbestos body concentration in lung cancer patients with occupational asbestos exposure.

Yusa T, Hiroshima K, Sakai F, Kishimoto T, Ohnishi K, Usami I, Morikawa T, Wu D, Itoi K, Okamoto K, Shinohara Y, Kohyama N, Morinaga K.

Am J Ind Med. 2015 Apr;58(4):444-55. doi: 10.1002/ajim.22430. Epub 2015 Feb 11.

PMID:
25676175
8.

Genetic polymorphism of the human organic solute carrier protein 1 (hOSCP1) gene in Japanese patients with non-viral liver carcinoma.

Toda M, Kobayashi Y, Koizumi T, Saito K, Ohbayashi M, Kohyama N, Aoki T, Murakami M, Yasuhara H, Yamamoto T.

Meta Gene. 2014 Oct 1;2:686-93. doi: 10.1016/j.mgene.2014.09.002. eCollection 2014 Dec.

9.

Rat model demonstrates a high risk of tremolite but a low risk of anthophyllite for mesothelial carcinogenesis.

Aierken D, Okazaki Y, Chew SH, Sakai A, Wang Y, Nagai H, Misawa N, Kohyama N, Toyokuni S.

Nagoya J Med Sci. 2014 Feb;76(1-2):149-60.

10.

Combined effects of asbestos and cigarette smoke on the development of lung adenocarcinoma: different carcinogens may cause different genomic changes.

Inamura K, Ninomiya H, Nomura K, Tsuchiya E, Satoh Y, Okumura S, Nakagawa K, Takata A, Kohyama N, Ishikawa Y.

Oncol Rep. 2014 Aug;32(2):475-82. doi: 10.3892/or.2014.3263. Epub 2014 Jun 13.

11.

Gene polymorphism and frequencies of the NPC1L1 gene (rs2072183, rs217434 and rs217428) in Japanese patients with dyslipidemia.

Kashiwabara Y, Kobayashi Y, Koba S, Kohyama N, Ohbayashi M, Murayama JI, Hirano T, Kobayashi Y, Yamamoto T.

J Clin Pharm Ther. 2014 Oct;39(5):551-4. doi: 10.1111/jcpt.12176. Epub 2014 May 26.

PMID:
24861377
12.

Involvement of epithelial-mesenchymal transition in methotrexate-induced pulmonary fibrosis.

Ohbayashi M, Kubota S, Kawase A, Kohyama N, Kobayashi Y, Yamamoto T.

J Toxicol Sci. 2014 Apr;39(2):319-30.

13.

Characterization of monocarboxylate transporter 6: expression in human intestine and transport of the antidiabetic drug nateglinide.

Kohyama N, Shiokawa H, Ohbayashi M, Kobayashi Y, Yamamoto T.

Drug Metab Dispos. 2013 Nov;41(11):1883-7. doi: 10.1124/dmd.113.051854. Epub 2013 Aug 9.

PMID:
23935065
14.
15.

Hordatine A β-D-glucopyranoside from ungerminated barley grains.

Kohyama N, Ono H.

J Agric Food Chem. 2013 Feb 6;61(5):1112-6. doi: 10.1021/jf304453c. Epub 2013 Jan 24.

PMID:
23320742
16.

Iron overload signature in chrysotile-induced malignant mesothelioma.

Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y, Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama N, Takahashi T, Toyokuni S.

J Pathol. 2012 Nov;228(3):366-77. doi: 10.1002/path.4075. Epub 2012 Aug 2.

PMID:
22864872
17.

Functional characterization and substrate specificity of a novel gene encoding zinc finger-like protein, ZfLp, in Xenopus laevis oocytes.

Kobayashi Y, Umemoto T, Takeshita Y, Kohyama N, Ohbayashi M, Sanada Y, Yamamoto T.

J Toxicol Sci. 2012;37(4):699-709.

18.

Introducing site-specific glycosylation using protein engineering techniques reduces the immunogenicity of β-lactoglobulin.

Tatsumi Y, Sasahara Y, Kohyama N, Ayano S, Endo M, Yoshida T, Yamada K, Totsuka M, Hattori M.

Biosci Biotechnol Biochem. 2012;76(3):478-85.

19.

[Molecular cloning and functional characterization of a novel gene encoding human prostaglandin carrier, hPrC].

Kobayashi Y, Nojima J, Ohbayashi M, Kohyama N, Yamamoto T.

Yakugaku Zasshi. 2011;131(10):1493-501. Japanese.

20.

Evaluation of sensitivity of fluorescence-based asbestos detection by correlative microscopy.

Ishida T, Alexandrov M, Nishimura T, Minakawa K, Hirota R, Sekiguchi K, Kohyama N, Kuroda A.

J Fluoresc. 2012 Jan;22(1):357-63. doi: 10.1007/s10895-011-0967-3. Epub 2011 Sep 21.

PMID:
21932006
21.

Ribosomal protein L3 mediated the transport of digoxin in Xenopus laevis oocyte.

Kobayashi Y, Kawakami K, Ohbayashi M, Kohyama N, Yamamoto T.

J Toxicol Sci. 2010 Dec;35(6):827-34.

22.

Effectiveness of serum megakaryocyte potentiating factor in evaluating the effects of chrysotile and its heated products on respiratory organs.

Takata A, Yamauchi H, Toya T, Miyamoto-Kohno S, Iwatatsu Y, Teranaka I, Aminaka M, Yamashita K, Kohyama N.

Toxicol Appl Pharmacol. 2011 Apr 15;252(2):123-9. doi: 10.1016/j.taap.2010.09.026. Epub 2010 Oct 8.

PMID:
20933535
23.

Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.

Ohbayashi M, Suzuki M, Yashiro Y, Fukuwaka S, Yasuda M, Kohyama N, Kobayashi Y, Yamamoto T.

J Toxicol Sci. 2010 Oct;35(5):653-61.

24.

Activation of cyclosporin A transport by a novel lambda light chain of human Ig surface antigen-related gene in Xenopus laevis oocytes.

Kobayashi Y, Umemoto T, Ohbayashi M, Kohyama N, Sanada Y, Yamamoto T.

Drug Metab Dispos. 2010 Sep;38(9):1427-35. doi: 10.1124/dmd.109.030916. Epub 2010 Jun 14.

PMID:
20547965
25.

Pulmonary toxicity induced by intratracheal instillation of coarse and fine particles of cerium dioxide in male rats.

Toya T, Takata A, Otaki N, Takaya M, Serita F, Yoshida K, Kohyama N.

Ind Health. 2010;48(1):3-11.

26.

Selective detection of airborne asbestos fibers using protein-based fluorescent probes.

Ishida T, Alexandrov M, Nishimura T, Minakawa K, Hirota R, Sekiguchi K, Kohyama N, Kuroda A.

Environ Sci Technol. 2010 Jan 15;44(2):755-9. doi: 10.1021/es902395h.

PMID:
20000675
27.

Forsterite exposure causes less oxidative DNA damage and lung injury than chrysotile exposure in rats.

Takata A, Yamauchi H, Toya T, Aminaka M, Shinohara Y, Kohyama N, Yoshida K.

Inhal Toxicol. 2009 Aug;21(9):739-46. doi: 10.1080/08958370802492399.

PMID:
19645569
28.

Effects of phenolic compounds on the browning of cooked barley.

Kohyama N, Fujita M, Ono H, Ohnishi-Kameyama M, Matsunaka H, Takayama T, Murata M.

J Agric Food Chem. 2009 Jul 22;57(14):6402-7. doi: 10.1021/jf901944m.

PMID:
19601672
29.

Microstructures and biological influence of environmental exposure of asbestos.

Yada K, Kohyama N.

Biomed Mater Eng. 2009;19(2-3):231-9. doi: 10.3233/BME-2009-0585. Review.

PMID:
19581718
30.

Mesothelioma in a worker who spun chrysotile asbestos at home during childhood.

Yano E, Wang ZM, Wang XR, Wang MZ, Takata A, Kohyama N, Suzuki Y.

Am J Ind Med. 2009 Apr;52(4):282-7. doi: 10.1002/ajim.20675.

PMID:
19143009
31.

Effect of interleukins response to ECM-induced acquisition of drug resistance in MCF-7 cells.

Ohbayashi M, Yasuda M, Kawakami I, Kohyama N, Kobayashi Y, Yamamoto T.

Exp Oncol. 2008 Dec;30(4):276-82.

PMID:
19112424
32.

Characteristics and modifying factors of asbestos-induced oxidative DNA damage.

Jiang L, Nagai H, Ohara H, Hara S, Tachibana M, Hirano S, Shinohara Y, Kohyama N, Akatsuka S, Toyokuni S.

Cancer Sci. 2008 Nov;99(11):2142-51. doi: 10.1111/j.1349-7006.2008.00934.x. Epub 2008 Sep 4.

33.

Descriptive study on the circumstances concerning confirmation of contraindications and careful administration upon purchasing over-the-counter cold medication and manifestation of after-use urinary disorders.

Sasaki K, Ohbayashi M, Kohyama N, Kobayashi Y, Yamamoto T.

Yakugaku Zasshi. 2008 Sep;128(9):1301-9. Erratum in: Yakugaku Zasshi. 2009 Jun;129(6):781.

34.

Changes in anthocyanins in the grains of purple waxy hull-less barley during seed maturation and after harvest.

Kohyama N, Ono H, Yanagisawa T.

J Agric Food Chem. 2008 Jul 23;56(14):5770-4. doi: 10.1021/jf800626b. Epub 2008 Jun 18.

PMID:
18558760
35.

Rat organic solute carrier protein 1 (rOscp1) mediated the transport of organic solutes in Xenopus laevis oocytes: isolation and pharmacological characterization of rOscp1.

Izuno H, Kobayashi Y, Sanada Y, Nihei D, Suzuki M, Kohyama N, Ohbayashi M, Yamamoto T.

Life Sci. 2007 Sep 22;81(15):1183-92. Epub 2007 Aug 19.

PMID:
17884105
36.

Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells.

Ohtani H, Ikegawa T, Honda Y, Kohyama N, Morimoto S, Shoyama Y, Juichi M, Naito M, Tsuruo T, Sawada Y.

Pharm Res. 2007 Oct;24(10):1936-43. Epub 2007 May 10.

PMID:
17492365
37.

Isolation and characterization of polyspecific mouse organic solute carrier protein 1 (mOscp1).

Kobayashi Y, Tsuchiya A, Hayashi T, Kohyama N, Ohbayashi M, Yamamoto T.

Drug Metab Dispos. 2007 Jul;35(7):1239-45. Epub 2007 Apr 19.

PMID:
17446263
38.

Behavior of rock wool in rat lungs after exposure by nasal inhalation.

Kudo Y, Kohyama N, Satoh T, Konishi Y, Aizawa Y.

J Occup Health. 2006 Nov;48(6):437-45.

39.

Dissolution of functional materials and rare earth oxides into pseudo alveolar fluid.

Takaya M, Shinohara Y, Serita F, Ono-Ogasawara M, Otaki N, Toya T, Takata A, Yoshida K, Kohyama N.

Ind Health. 2006 Oct;44(4):639-44.

40.

Lung disorders of workers exposed to rush smear dust in China.

Xiao GB, Morinaga K, Wang RY, Xu LR, Ma ZH, Zhang X, Kishimoto T, Kohyama N.

Ind Health. 2006 Oct;44(4):556-63.

41.

Field evaluation of mercury vapor analytical methods: comparison of the "double amalgam method" and ISO 17733.

Takaya M, Joeng JY, Ishihara N, Serita F, Kohyama N.

Ind Health. 2006 Apr;44(2):287-90.

42.

Mouse organic anion transporter 2 and 3 (mOAT2/3[Slc22a7/8]) mediates the renal transport of bumetanide.

Kobayashi Y, Ohbayashi M, Kohyama N, Yamamoto T.

Eur J Pharmacol. 2005 Nov 7;524(1-3):44-8. Epub 2005 Oct 27.

PMID:
16256982
43.

Functional characterization of human monocarboxylate transporter 6 (SLC16A5).

Murakami Y, Kohyama N, Kobayashi Y, Ohbayashi M, Ohtani H, Sawada Y, Yamamoto T.

Drug Metab Dispos. 2005 Dec;33(12):1845-51. Epub 2005 Sep 20.

PMID:
16174808
44.

Behavior of new type of rock wool (HT wool) in lungs after exposure by nasal inhalation in rats.

Kudo Y, Shibata K, Miki T, Ishibashi M, Hosoi K, Sato T, Kohyama N, Aizawa Y.

Environ Health Prev Med. 2005 Sep;10(5):239-48. doi: 10.1007/BF02897697.

45.

Dendriform pulmonary ossification in patient with rare earth pneumoconiosis.

Yoon HK, Moon HS, Park SH, Song JS, Lim Y, Kohyama N.

Thorax. 2005 Aug;60(8):701-3.

46.

Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1.

Kobayashi Y, Shibusawa A, Saito H, Ohshiro N, Ohbayashi M, Kohyama N, Yamamoto T.

J Biol Chem. 2005 Sep 16;280(37):32332-9. Epub 2005 Jul 8.

47.

Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]).

Kobayashi Y, Ohshiro N, Sakai R, Ohbayashi M, Kohyama N, Yamamoto T.

J Pharm Pharmacol. 2005 May;57(5):573-8.

PMID:
15901346
48.

An autopsy case of primary pericardial mesothelioma in arc cutter exposed to asbestos through talc pencils.

Fujiwara H, Kamimori T, Morinaga K, Takeda Y, Kohyama N, Miki Y, Inai K, Yamamoto S.

Ind Health. 2005 Apr;43(2):346-50.

49.

Synthesis of a methylene analog of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide monophosphate (ZMP).

Kohyama N, Hayashi T, Yamamoto Y.

Biosci Biotechnol Biochem. 2005 Apr;69(4):836-8.

50.

Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C.

Chatani S, Nakamura M, Akahane H, Kohyama N, Taki M, Arata T, Yamamoto Y.

Chem Commun (Camb). 2005 Apr 14;(14):1880-2. Epub 2005 Feb 11.

PMID:
15795774

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