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Items: 26

1.

Additive effect of simultaneous continuous administration of degarelix and TAK-448 on LH suppression in a castrated rat model.

Stalewski J, Hargrove DM, Wolfe M, Kohout TA, Kamal A.

Eur J Pharmacol. 2018 Apr 5;824:24-29. doi: 10.1016/j.ejphar.2018.01.033. Epub 2018 Feb 3.

PMID:
29378196
2.

Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium.

Matson BC, Pierce SL, Espenschied ST, Holle E, Sweatt IH, Davis ES, Tarran R, Young SL, Kohout TA, van Duin M, Caron KM.

Biol Reprod. 2017 Sep 1;97(3):466-477. doi: 10.1093/biolre/iox101.

3.

Validation and application of a liquid chromatography-tandem mass spectrometric method for the simultaneous determination of testosterone and dihydrotestosterone in rat prostatic tissue using a 96-well format.

O'Brien Z, Post N, Brown M, Madan A, Coon T, Luo R, Kohout TA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3515-21. doi: 10.1016/j.jchromb.2009.08.053. Epub 2009 Sep 9.

PMID:
19767251
4.

Trapping of a nonpeptide ligand by the extracellular domains of the gonadotropin-releasing hormone receptor results in insurmountable antagonism.

Kohout TA, Xie Q, Reijmers S, Finn KJ, Guo Z, Zhu YF, Struthers RS.

Mol Pharmacol. 2007 Aug;72(2):238-47. Epub 2007 Apr 4.

PMID:
17409285
5.

Pharmacological characterization of a novel nonpeptide antagonist of the human gonadotropin-releasing hormone receptor, NBI-42902.

Struthers RS, Xie Q, Sullivan SK, Reinhart GJ, Kohout TA, Zhu YF, Chen C, Liu XJ, Ling N, Yang W, Maki RA, Bonneville AK, Chen TK, Bozigian HP.

Endocrinology. 2007 Feb;148(2):857-67. Epub 2006 Nov 9.

PMID:
17095587
6.

beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts.

Gesty-Palmer D, El Shewy H, Kohout TA, Luttrell LM.

J Biol Chem. 2005 Sep 16;280(37):32157-67. Epub 2005 Jul 15.

7.

Distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated.

Perry SJ, Junger S, Kohout TA, Hoare SR, Struthers RS, Grigoriadis DE, Maki RA.

J Biol Chem. 2005 Mar 25;280(12):11560-8. Epub 2005 Jan 14.

8.

Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling.

Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB.

J Biol Chem. 2005 Mar 11;280(10):8722-32. Epub 2004 Dec 7.

9.

Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7.

Kohout TA, Nicholas SL, Perry SJ, Reinhart G, Junger S, Struthers RS.

J Biol Chem. 2004 May 28;279(22):23214-22. Epub 2004 Mar 30.

10.

Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis.

Povsic TJ, Kohout TA, Lefkowitz RJ.

J Biol Chem. 2003 Dec 19;278(51):51334-9. Epub 2003 Oct 8.

11.

N-formyl peptide receptors internalize but do not recycle in the absence of arrestins.

Vines CM, Revankar CM, Maestas DC, LaRusch LL, Cimino DF, Kohout TA, Lefkowitz RJ, Prossnitz ER.

J Biol Chem. 2003 Oct 24;278(43):41581-4. Epub 2003 Aug 28.

12.

The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor.

Wu JH, Peppel K, Nelson CD, Lin FT, Kohout TA, Miller WE, Exum ST, Freedman NJ.

J Biol Chem. 2003 Nov 7;278(45):44238-45. Epub 2003 Aug 27.

13.
14.

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization.

Kohout TA, Lefkowitz RJ.

Mol Pharmacol. 2003 Jan;63(1):9-18. Review. No abstract available.

PMID:
12488531
15.

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins.

Perry SJ, Baillie GS, Kohout TA, McPhee I, Magiera MM, Ang KL, Miller WE, McLean AJ, Conti M, Houslay MD, Lefkowitz RJ.

Science. 2002 Oct 25;298(5594):834-6.

16.

Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2.

Hanyaloglu AC, Seeber RM, Kohout TA, Lefkowitz RJ, Eidne KA.

J Biol Chem. 2002 Dec 27;277(52):50422-30. Epub 2002 Oct 21.

17.

Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice.

Kohout TA, Takaoka H, McDonald PH, Perry SJ, Mao L, Lefkowitz RJ, Rockman HA.

Circulation. 2001 Nov 13;104(20):2485-91.

PMID:
11705829
18.

beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation.

Paing MM, Stutts AB, Kohout TA, Lefkowitz RJ, Trejo J.

J Biol Chem. 2002 Jan 11;277(2):1292-300. Epub 2001 Nov 2.

19.

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin.

Shenoy SK, McDonald PH, Kohout TA, Lefkowitz RJ.

Science. 2001 Nov 9;294(5545):1307-13. Epub 2001 Oct 4.

20.

beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking.

Kohout TA, Lin FS, Perry SJ, Conner DA, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1601-6. Epub 2001 Feb 6.

21.

Ca(2+) channel modulation by recombinant auxiliary beta subunits expressed in young adult heart cells.

Wei SK, Colecraft HM, DeMaria CD, Peterson BZ, Zhang R, Kohout TA, Rogers TB, Yue DT.

Circ Res. 2000 Feb 4;86(2):175-84.

PMID:
10666413
22.

Novel adenovirus component system that transfects cultured cardiac cells with high efficiency.

Kohout TA, O'Brian JJ, Gaa ST, Lederer WJ, Rogers TB.

Circ Res. 1996 Jun;78(6):971-7.

PMID:
8635247
23.
24.

Use of a PCR-based method to characterize protein kinase C isoform expression in cardiac cells.

Kohout TA, Rogers TB.

Am J Physiol. 1993 May;264(5 Pt 1):C1350-9.

PMID:
7684564
25.

Molecular and cellular actions of platelet-activating factor in rat heart cells.

Massey CV, Kohout TA, Gaa ST, Lederer WJ, Rogers TB.

J Clin Invest. 1991 Dec;88(6):2106-16.

26.

Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line.

Gordon EA, Kohout TA, Fishman PH.

J Neurochem. 1990 Aug;55(2):506-13.

PMID:
2164571

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