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Items: 1 to 50 of 329

1.

Propylthiouracil increases sodium/iodide symporter gene expression and iodide uptake in rat thyroid cells in the absence of TSH.

Sue M, Akama T, Kawashima A, Nakamura H, Hara T, Tanigawa K, Wu H, Yoshihara A, Ishido Y, Hiroi N, Yoshino G, Kohn LD, Ishii N, Suzuki K.

Thyroid. 2012 Aug;22(8):844-52. doi: 10.1089/thy.2011.0290.

2.

A TSHr-LH/CGr chimera that measures functional TSAb in Graves' disease.

Giuliani C, Cerrone D, Harii N, Thornton M, Kohn LD, Dagia NM, Fiore E, Bucci I, Chamblin T, Vitti P, Monaco F, Napolitano G.

J Clin Endocrinol Metab. 2012 Jul;97(7):E1106-15. doi: 10.1210/jc.2011-2893. Epub 2012 Apr 10.

PMID:
22496495
3.

A TSHR-LH/CGR chimera that measures functional thyroid-stimulating autoantibodies (TSAb) can predict remission or recurrence in Graves' patients undergoing antithyroid drug (ATD) treatment.

Giuliani C, Cerrone D, Harii N, Thornton M, Kohn LD, Dagia NM, Bucci I, Carpentieri M, Di Nenno B, Di Blasio A, Vitti P, Monaco F, Napolitano G.

J Clin Endocrinol Metab. 2012 Jul;97(7):E1080-7. doi: 10.1210/jc.2011-2897. Epub 2012 Apr 6.

PMID:
22492869
4.

Increased Wnt5a mRNA Expression in Advanced Atherosclerotic Lesions, and Oxidized LDL Treated Human Monocyte-Derived Macrophages.

Bhatt PM, Lewis CJ, House DL, Keller CM, Kohn LD, Silver MJ, McCall KD, Goetz DJ, Malgor R.

Open Circ Vasc J. 2012;5:1-7.

5.

Phenylmethimazole inhibits production of proinflammatory mediators and is protective in an experimental model of endotoxic shock*.

Benavides U, Gonzalez-Murguiondo M, Harii N, Lewis CJ, Schwartz AL, Giuliani C, Napolitano G, Dagia NM, Malgor R, McCall KD, Kohn LD.

Crit Care Med. 2012 Mar;40(3):886-94. doi: 10.1097/CCM.0b013e318236ef8b.

PMID:
22020240
6.

Novel chimeric thyroid-stimulating hormone-receptor bioassay for thyroid-stimulating immunoglobulins.

Lytton SD, Li Y, Olivo PD, Kohn LD, Kahaly GJ.

Clin Exp Immunol. 2010 Dec;162(3):438-46. doi: 10.1111/j.1365-2249.2010.04266.x.

7.

Phenylmethimazole blocks palmitate-mediated induction of inflammatory cytokine pathways in 3T3L1 adipocytes and RAW 264.7 macrophages.

McCall KD, Holliday D, Dickerson E, Wallace B, Schwartz AL, Schwartz C, Lewis CJ, Kohn LD, Schwartz FL.

J Endocrinol. 2010 Dec;207(3):343-53. doi: 10.1677/JOE-09-0370. Epub 2010 Sep 2.

PMID:
20813836
8.

Phenyl methimazole suppresses dextran sulfate sodium-induced murine colitis.

Benavides U, Gonzalez-Murguiondo M, Harii N, Lewis CJ, Sakhalkar HS, Deosarkar SP, Kurjiaka DT, Dagia NM, Goetz DJ, Kohn LD.

Eur J Pharmacol. 2010 Sep 15;643(1):129-38. doi: 10.1016/j.ejphar.2010.06.003. Epub 2010 Jun 13.

PMID:
20550948
9.

A novel thyroid stimulating immunoglobulin bioassay is a functional indicator of activity and severity of Graves' orbitopathy.

Lytton SD, Ponto KA, Kanitz M, Matheis N, Kohn LD, Kahaly GJ.

J Clin Endocrinol Metab. 2010 May;95(5):2123-31. doi: 10.1210/jc.2009-2470. Epub 2010 Mar 17.

PMID:
20237164
10.

Excess iodide decreases transcription of NIS and VEGF genes in rat FRTL-5 thyroid cells.

Suzuki K, Kimura H, Wu H, Kudo N, Kim WB, Suzuki S, Yoshida A, Caturegli P, Kohn LD.

Biochem Biophys Res Commun. 2010 Mar 5;393(2):286-90. doi: 10.1016/j.bbrc.2010.01.123. Epub 2010 Feb 2.

11.

Thyroglobulin (Tg) induces thyroid cell growth in a concentration-specific manner by a mechanism other than thyrotropin/cAMP stimulation.

Noguchi Y, Harii N, Giuliani C, Tatsuno I, Suzuki K, Kohn LD.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):890-4. doi: 10.1016/j.bbrc.2009.11.158. Epub 2009 Nov 29.

PMID:
19951699
12.

A sandwich ELISA for the detection of Wnt5a.

Kummitha CM, Mayle KM, Christman MA 2nd, Deosarkar SP, Schwartz AL, McCall KD, Kohn LD, Malgor R, Goetz DJ.

J Immunol Methods. 2010 Jan 31;352(1-2):38-44. doi: 10.1016/j.jim.2009.11.005. Epub 2009 Nov 15.

13.

Regulation of major histocompatibility complex gene expression in thyroid epithelial cells by methimazole and phenylmethimazole.

Giuliani C, Bucci I, Montani V, Singer DS, Monaco F, Kohn LD, Napolitano G.

J Endocrinol. 2010 Jan;204(1):57-66. doi: 10.1677/JOE-09-0172. Epub 2009 Oct 16.

14.

Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration.

Schwartz AL, Malgor R, Dickerson E, Weeraratna AT, Slominski A, Wortsman J, Harii N, Kohn AD, Moon RT, Schwartz FL, Goetz DJ, Kohn LD, McCall KD.

Clin Cancer Res. 2009 Jun 15;15(12):4114-22. doi: 10.1158/1078-0432.CCR-09-0005. Epub 2009 May 26.

15.

Wnt5a is expressed in murine and human atherosclerotic lesions.

Christman MA 2nd, Goetz DJ, Dickerson E, McCall KD, Lewis CJ, Benencia F, Silver MJ, Kohn LD, Malgor R.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2864-70. doi: 10.1152/ajpheart.00982.2007. Epub 2008 May 2.

16.

Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis.

Deosarkar SP, Malgor R, Fu J, Kohn LD, Hanes J, Goetz DJ.

Biotechnol Bioeng. 2008 Oct 1;101(2):400-7. doi: 10.1002/bit.21885.

PMID:
18428114
17.

Enhancement of experimental Graves' disease by intranasal administration of a T cell epitope of the thyrotropin receptor.

Arima T, Shimojo N, Yamaguchi K, Tomiita M, Kohn LD, Kohno Y.

Clin Immunol. 2008 Apr;127(1):7-13. doi: 10.1016/j.clim.2007.11.007. Epub 2008 Jan 29.

PMID:
18234558
18.

The flavonoid quercetin regulates growth and gene expression in rat FRTL-5 thyroid cells.

Giuliani C, Noguchi Y, Harii N, Napolitano G, Tatone D, Bucci I, Piantelli M, Monaco F, Kohn LD.

Endocrinology. 2008 Jan;149(1):84-92. Epub 2007 Oct 25.

PMID:
17962351
19.
20.

TGF-beta-like transcriptional effects of thyroglobulin (Tg) in mouse mesangial cells.

Sellitti DF, Puggina E, Lagranha C, Doi S, Pithon-Curi T, Kohn LD, Suzuki K.

Endocr J. 2007 Jun;54(3):449-58. Epub 2007 May 9.

21.

Upstream stimulatory factor regulates constitutive expression and hormonal suppression of the 90K (Mac-2BP) protein.

Grassadonia A, Tinari N, Fiorentino B, Nakazato M, Chung HK, Giuliani C, Napolitano G, Iacobelli S, Howcroft TK, Singer DS, Kohn LD; Consorzio Interuniversitario Nazionale per la Bioncologia.

Endocrinology. 2007 Jul;148(7):3507-17. Epub 2007 Apr 19.

PMID:
17446190
22.

Overexpression of Wnt-1 in thyrocytes enhances cellular growth but suppresses transcription of the thyroperoxidase gene via different signaling mechanisms.

Kim WB, Lewis CJ, McCall KD, Malgor R, Kohn AD, Moon RT, Kohn LD.

J Endocrinol. 2007 Apr;193(1):93-106.

PMID:
17400807
23.

Transcriptional regulation of major histocompatibility complex class I gene by insulin and IGF-I in FRTL-5 thyroid cells.

Giuliani C, Saji M, Bucci I, Fiore G, Liberatore M, Singer DS, Monaco F, Kohn LD, Napolitano G.

J Endocrinol. 2006 Jun;189(3):605-15.

PMID:
16731791
24.
25.

Is type 2 diabetes an autoimmune-inflammatory disorder of the innate immune system?

Kohn LD, Wallace B, Schwartz F, McCall K.

Endocrinology. 2005 Oct;146(10):4189-91. No abstract available.

PMID:
16166230
26.

Enhanced adhesion of ligand-conjugated biodegradable particles to colitic venules.

Sakhalkar HS, Hanes J, Fu J, Benavides U, Malgor R, Borruso CL, Kohn LD, Kurjiaka DT, Goetz DJ.

FASEB J. 2005 May;19(7):792-4. Epub 2005 Mar 11.

PMID:
15764649
27.

Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.

Harii N, Lewis CJ, Vasko V, McCall K, Benavides-Peralta U, Sun X, Ringel MD, Saji M, Giuliani C, Napolitano G, Goetz DJ, Kohn LD.

Mol Endocrinol. 2005 May;19(5):1231-50. Epub 2005 Jan 20.

PMID:
15661832
28.
29.

The 90K protein increases major histocompatibility complex class I expression and is regulated by hormones, gamma-interferon, and double-strand polynucleotides.

Grassadonia A, Tinari N, Fiorentino B, Suzuki K, Nakazato M, De Tursi M, Giuliani C, Napolitano G, Singer DS, Iacobelli S, Kohn LD.

Endocrinology. 2004 Oct;145(10):4728-36. Epub 2004 Jul 1.

PMID:
15231701
30.

Mechanism of iodide/chloride exchange by pendrin.

Yoshida A, Hisatome I, Taniguchi S, Sasaki N, Yamamoto Y, Miake J, Fukui H, Shimizu H, Okamura T, Okura T, Igawa O, Shigemasa C, Green ED, Kohn LD, Suzuki K.

Endocrinology. 2004 Sep;145(9):4301-8. Epub 2004 May 20.

PMID:
15155570
31.

Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways.

Fuse M, Tanaka T, Shibata T, Yoshida T, Noguchi Y, Misawa N, Yasuda T, Saito Y, Kohn LD, Tatsuno I.

Biochem Biophys Res Commun. 2004 Mar 19;315(4):1147-53.

PMID:
14985133
32.

The effect of posttranslational modifications on the in vitro activity of recombinant human thyroid-stimulating hormone.

Sendak RA, Ganesa C, Lee KL, Harrahy JJ, Th├ęberge R, Morgan CJ, Cole ES, Kohn LD, Mattaliano RJ.

Thyroid. 2003 Dec;13(12):1091-101.

PMID:
14751029
33.

Thyrotropin receptor autoantibodies (TSHRAbs): epitopes, origins and clinical significance.

Kohn LD, Harii N.

Autoimmunity. 2003 Sep-Nov;36(6-7):331-7. Review.

PMID:
14669940
34.

The RHL-1 subunit of the asialoglycoprotein receptor of thyroid cells: cellular localization and its role in thyroglobulin endocytosis.

Pacifico F, Montuori N, Mellone S, Liguoro D, Ulianich L, Caleo A, Troncone G, Kohn LD, Di Jeso B, Consiglio E.

Mol Cell Endocrinol. 2003 Oct 31;208(1-2):51-9.

PMID:
14580721
35.

Thyrotropin-mediated repression of class II trans-activator expression in thyroid cells: involvement of STAT3 and suppressor of cytokine signaling.

Kim H, Suh JM, Hwang ES, Kim DW, Chung HK, Song JH, Hwang JH, Park KC, Ro HK, Jo EK, Chang JS, Lee TH, Lee MS, Kohn LD, Shong M.

J Immunol. 2003 Jul 15;171(2):616-27.

36.

Regulatory CD8+ T cells control thyrotropin receptor-specific CD4+ clones in healthy subjects.

Molteni M, Rossetti C, Scrofani S, Bonara P, Scorza R, Kohn LD.

Cancer Detect Prev. 2003;27(3):167-74.

PMID:
12787722
37.

Methimazole protects from experimental autoimmune uveitis (EAU) by inhibiting antigen presenting cell function and reducing antigen priming.

Wang P, Sun SH, Silver PB, Chan CC, Agarwal RK, Wiggert B, Kohn LD, Jamieson GA Jr, Caspi RR.

J Leukoc Biol. 2003 Jan;73(1):57-64.

PMID:
12525562
38.

Epitope heterogeneity of thyroid-stimulating antibodies predicts long-term outcome in Graves' patients treated with antithyroid drugs.

Kim TY, Park YJ, Park DJ, Chung HK, Kim WB, Kohn LD, Cho BY.

J Clin Endocrinol Metab. 2003 Jan;88(1):117-24.

PMID:
12519839
39.
40.

Retention of pendrin in the endoplasmic reticulum is a major mechanism for Pendred syndrome.

Rotman-Pikielny P, Hirschberg K, Maruvada P, Suzuki K, Royaux IE, Green ED, Kohn LD, Lippincott-Schwartz J, Yen PM.

Hum Mol Genet. 2002 Oct 1;11(21):2625-33.

PMID:
12354788
41.

Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entry.

Triyatni M, Saunier B, Maruvada P, Davis AR, Ulianich L, Heller T, Patel A, Kohn LD, Liang TJ.

J Virol. 2002 Sep;76(18):9335-44.

42.

Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells.

Yoshida A, Taniguchi S, Hisatome I, Royaux IE, Green ED, Kohn LD, Suzuki K.

J Clin Endocrinol Metab. 2002 Jul;87(7):3356-61.

PMID:
12107249
43.

Co-expression of the CD8 receptor in a human CD4+ T-cell clone influences proliferation, cytosolic Ca2+ release and cytokine production.

Molteni M, Kohn LD, Rossetti C, Scrofani S, Bonara P, Scorza R.

Immunol Lett. 2002 Sep 2;83(2):111-7.

PMID:
12067759
44.

Transfection of single-stranded hepatitis A virus RNA activates MHC class I pathway.

Suzuki K, Yanagi M, Mori-Aoki A, Moriyama E, Ishii KJ, Kohn LD.

Clin Exp Immunol. 2002 Feb;127(2):234-42.

45.

High glucose levels increase major histocompatibility complex class I gene expression in thyroid cells and amplify interferon-gamma action.

Napolitano G, Bucci I, Giuliani C, Massafra C, Di Petta C, Devangelio E, Singer DS, Monaco F, Kohn LD.

Endocrinology. 2002 Mar;143(3):1008-17.

PMID:
11861526
46.

Expression of PDS/Pds, the Pendred syndrome gene, in endometrium.

Suzuki K, Royaux IE, Everett LA, Mori-Aoki A, Suzuki S, Nakamura K, Sakai T, Katoh R, Toda S, Green ED, Kohn LD.

J Clin Endocrinol Metab. 2002 Feb;87(2):938.

PMID:
11836344
47.

Thyroglobulin autoregulation of thyroid-specific gene expression and follicular function.

Suzuki K, Nakazato M, Ulianich L, Mori-Aoki A, Moriyama E, Chung HK, Pietrarelli M, Grassadonia A, Matoba H, Kohn LD.

Rev Endocr Metab Disord. 2000 Apr;1(3):217-24. Review. No abstract available.

PMID:
11705006
48.

An animal model of Graves' disease: understanding the cause of autoimmune hyperthyroidism.

Kohn LD, Shimojo N, Kohno Y, Suzuki K.

Rev Endocr Metab Disord. 2000 Jan;1(1-2):59-67. Review. No abstract available.

PMID:
11704993
49.

Genomic DNA released by dying cells induces the maturation of APCs.

Ishii KJ, Suzuki K, Coban C, Takeshita F, Itoh Y, Matoba H, Kohn LD, Klinman DM.

J Immunol. 2001 Sep 1;167(5):2602-7.

50.

Overexpression and overactivation of Akt in thyroid carcinoma.

Ringel MD, Hayre N, Saito J, Saunier B, Schuppert F, Burch H, Bernet V, Burman KD, Kohn LD, Saji M.

Cancer Res. 2001 Aug 15;61(16):6105-11.

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