Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 846


Development, Validation and Pilot Field Deployment of a Custom Mouthpiece for Head Impact Measurement.

Rich AM, Filben TM, Miller LE, Tomblin BT, Van Gorkom AR, Hurst MA, Barnard RT, Kohn DS, Urban JE, Stitzel JD.

Ann Biomed Eng. 2019 Jul 11. doi: 10.1007/s10439-019-02313-1. [Epub ahead of print]


[Tumour endoprosthetic replacement after sarcoma resection].

Orth P, Kohn D.

Orthopade. 2019 Jul;48(7):553-554. doi: 10.1007/s00132-019-03761-2. German. No abstract available.


Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates.

Romero Z, Lomova A, Said S, Miggelbrink A, Kuo CY, Campo-Fernandez B, Hoban MD, Masiuk KE, Clark DN, Long J, Sanchez JM, Velez M, Miyahira E, Zhang R, Brown D, Wang X, Kurmangaliyev YZ, Hollis RP, Kohn DB.

Mol Ther. 2019 May 24. pii: S1525-0016(19)30228-X. doi: 10.1016/j.ymthe.2019.05.014. [Epub ahead of print]


"Simple mechanical devices did not improve pelvis positioning in AP pelvis radiographs for reliable assessment of the acetabular orientation".

Brockmeyer M, Lott S, Stroeder J, Fries P, Wagenpfeil S, Tschernig T, Kohn D.

J Exp Orthop. 2019 May 23;6(1):20. doi: 10.1186/s40634-019-0191-7.


[Endoprosthetic replacement following intercalary resection].

Goebel L, Kohn D, Orth P.

Orthopade. 2019 Jul;48(7):572-581. doi: 10.1007/s00132-019-03735-4. Review. German.


PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector.

Masiuk KE, Zhang R, Osborne K, Hollis RP, Campo-Fernandez B, Kohn DB.

Mol Ther Methods Clin Dev. 2019 Apr 4;13:390-398. doi: 10.1016/j.omtm.2019.03.005. eCollection 2019 Jun 14.



Kohn D.

Dtsch Arztebl Int. 2019 Mar 8;116(11):194. doi: 10.3238/arztebl.2019.0194b. No abstract available.


The anatomy of the anterolateral structures of the knee - A histologic and macroscopic approach.

Brockmeyer M, Orth P, Höfer D, Seil R, Paulsen F, Menger MD, Kohn D, Tschernig T.

Knee. 2019 Jun;26(3):636-646. doi: 10.1016/j.knee.2019.02.017. Epub 2019 Mar 23.


Cell and Material-Specific Phage Display Peptides Increase iPS-MSC Mediated Bone and Vasculature Formation In Vivo.

Ramaraju H, Kohn DH.

Adv Healthc Mater. 2019 May;8(9):e1801356. doi: 10.1002/adhm.201801356. Epub 2019 Mar 5.


Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.

Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS.

Stem Cell Res Ther. 2019 Feb 12;10(1):52. doi: 10.1186/s13287-019-1147-7.


Chemistry, manufacturing and controls for gene modified hematopoietic stem cells.

Soni S, Kohn DB.

Cytotherapy. 2019 Mar;21(3):358-366. doi: 10.1016/j.jcyt.2018.12.001. Epub 2019 Feb 8.


External Bone Size Is a Key Determinant of Strength-Decline Trajectories of Aging Male Radii.

Bigelow EM, Patton DM, Ward FS, Ciarelli A, Casden M, Clark A, Goulet RW, Morris MD, Schlecht SH, Mandair GS, Bredbenner TL, Kohn DH, Jepsen KJ.

J Bone Miner Res. 2019 May;34(5):825-837. doi: 10.1002/jbmr.3661. Epub 2019 Feb 4.


Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017.

Amatuni GS, Currier RJ, Church JA, Bishop T, Grimbacher E, Nguyen AA, Agarwal-Hashmi R, Aznar CP, Butte MJ, Cowan MJ, Dorsey MJ, Dvorak CC, Kapoor N, Kohn DB, Markert ML, Moore TB, Naides SJ, Sciortino S, Feuchtbaum L, Koupaei RA, Puck JM.

Pediatrics. 2019 Feb;143(2). pii: e20182300. doi: 10.1542/peds.2018-2300.


[Farewell to Der Orthopäde].

Ewerbeck V, Kohn D.

Orthopade. 2019 Jan;48(1):1-2. doi: 10.1007/s00132-018-03674-6. German. No abstract available.


[Persistent skin lesions after acute zoster infection].

Kohn D, Lupatsch F, Wetzig T.

Hautarzt. 2019 Mar;70(3):228-230. doi: 10.1007/s00105-018-4352-x. German. No abstract available.


Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome.

Masiuk KE, Laborada J, Roncarolo MG, Hollis RP, Kohn DB.

Cell Stem Cell. 2019 Feb 7;24(2):309-317.e7. doi: 10.1016/j.stem.2018.12.003. Epub 2019 Jan 10.


Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice.

Kwon HS, Logan AC, Chhabra A, Pang WW, Czechowicz A, Tate K, Le A, Poyser J, Hollis R, Kelly BV, Kohn DB, Weissman IL, Prohaska SS, Shizuru JA.

Blood. 2019 May 9;133(19):2104-2108. doi: 10.1182/blood-2018-06-853879. Epub 2019 Jan 7. No abstract available.


Gene therapy for blood diseases.

Kohn DB.

Curr Opin Biotechnol. 2018 Dec 29;60:39-45. doi: 10.1016/j.copbio.2018.11.016. [Epub ahead of print] Review.


Pre-clinical Development of a Lentiviral Vector Expressing the Anti-sickling βAS3 Globin for Gene Therapy for Sickle Cell Disease.

Poletti V, Urbinati F, Charrier S, Corre G, Hollis RP, Campo Fernandez B, Martin S, Rothe M, Schambach A, Kohn DB, Mavilio F.

Mol Ther Methods Clin Dev. 2018 Nov 1;11:167-179. doi: 10.1016/j.omtm.2018.10.014. eCollection 2018 Dec 14.


The relationship between whole bone stiffness and strength is age and sex dependent.

Patton DM, Bigelow EMR, Schlecht SH, Kohn DH, Bredbenner TL, Jepsen KJ.

J Biomech. 2019 Jan 23;83:125-133. doi: 10.1016/j.jbiomech.2018.11.030. Epub 2018 Nov 26.


IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System.

Puig-Saus C, Parisi G, Garcia-Diaz A, Krystofinski PE, Sandoval S, Zhang R, Champhekar AS, McCabe J, Cheung-Lau GC, Truong NA, Vega-Crespo A, Komenan MDS, Pang J, Macabali MH, Saco JD, Goodwin JL, Bolon B, Seet CS, Montel-Hagen A, Crooks GM, Hollis RP, Campo-Fernandez B, Bischof D, Cornetta K, Gschweng EH, Adelson C, Nguyen A, Yang L, Witte ON, Baltimore D, Comin-Anduix B, Kohn DB, Wang X, Cabrera P, Kaplan-Lefko PJ, Berent-Maoz B, Ribas A.

Clin Cancer Res. 2019 Feb 1;25(3):1000-1011. doi: 10.1158/1078-0432.CCR-18-0963. Epub 2018 Nov 8.


Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair.

Lomova A, Clark DN, Campo-Fernandez B, Flores-Bjurström C, Kaufman ML, Fitz-Gibbon S, Wang X, Miyahira EY, Brown D, DeWitt MA, Corn JE, Hollis RP, Romero Z, Kohn DB.

Stem Cells. 2019 Feb;37(2):284-294. doi: 10.1002/stem.2935. Epub 2018 Nov 27.


T cell dynamics and response of the microbiota after gene therapy to treat X-linked severe combined immunodeficiency.

Clarke EL, Connell AJ, Six E, Kadry NA, Abbas AA, Hwang Y, Everett JK, Hofstaedter CE, Marsh R, Armant M, Kelsen J, Notarangelo LD, Collman RG, Hacein-Bey-Abina S, Kohn DB, Cavazzana M, Fischer A, Williams DA, Pai SY, Bushman FD.

Genome Med. 2018 Sep 28;10(1):70. doi: 10.1186/s13073-018-0580-z.


Examining the influence of PTH(1-34) on tissue strength and composition.

Gardinier JD, Al-Omaishi S, Rostami N, Morris MD, Kohn DH.

Bone. 2018 Dec;117:130-137. doi: 10.1016/j.bone.2018.09.019. Epub 2018 Sep 24.


Combined mineral-supplemented diet and exercise increases bone mass and strength after eight weeks and maintains increases after eight weeks detraining in adult mice.

Friedman MA, Szczepankiewicz RP, Kohn DH.

PLoS One. 2018 Sep 21;13(9):e0204470. doi: 10.1371/journal.pone.0204470. eCollection 2018.


Detection of Herpes Simplex Virus and Varicella-Zoster Virus by Traditional and Multiplex Molecular Methods.

Nikolic D, Kohn D, Yen-Lieberman B, Procop GW.

Am J Clin Pathol. 2019 Jan 1;151(1):122-126. doi: 10.1093/ajcp/aqy111.


Gene Therapy for Sickle Cell Disease: A Lentiviral Vector Comparison Study.

Urbinati F, Campo Fernandez B, Masiuk KE, Poletti V, Hollis RP, Koziol C, Kaufman ML, Brown D, Mavilio F, Kohn DB.

Hum Gene Ther. 2018 Oct;29(10):1153-1166. doi: 10.1089/hum.2018.061.


Consensus approach for the management of severe combined immune deficiency caused by adenosine deaminase deficiency.

Kohn DB, Hershfield MS, Puck JM, Aiuti A, Blincoe A, Gaspar HB, Notarangelo LD, Grunebaum E.

J Allergy Clin Immunol. 2019 Mar;143(3):852-863. doi: 10.1016/j.jaci.2018.08.024. Epub 2018 Sep 5.


The genetic landscape of severe combined immunodeficiency in the United States and Canada in the current era (2010-2018).

Dvorak CC, Haddad E, Buckley RH, Cowan MJ, Logan B, Griffith LM, Kohn DB, Pai SY, Notarangelo L, Shearer W, Prockop S, Kapoor N, Heimall J, Chaudhury S, Shyr D, Chandra S, Cuvelier G, Moore T, Shenoy S, Goldman F, Smith AR, Sunkersett G, Vander Lugt M, Caywood E, Quigg T, Torgerson T, Chandrakasan S, Craddock J, Dávila Saldaña BJ, Gillio A, Shereck E, Aquino V, DeSantes K, Knutsen A, Thakar M, Yu L, Puck JM.

J Allergy Clin Immunol. 2019 Jan;143(1):405-407. doi: 10.1016/j.jaci.2018.08.027. Epub 2018 Sep 5. No abstract available.


Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization.

Hu P, Bi Y, Ma H, Suwanmanee T, Zeithaml B, Fry NJ, Kohn DB, Kafri T.

Gene Ther. 2018 Oct;25(7):454-472. doi: 10.1038/s41434-018-0039-2. Epub 2018 Sep 6.


Biological and Mechanical Evaluation of Novel Prototype Dental Composites.

Van der Laan HL, Zajdowicz SL, Kuroda K, Bielajew BJ, Davidson TA, Gardinier J, Kohn DH, Chahal S, Chang S, Liu J, Gerszberg J, Scott TF, Clarkson BH.

J Dent Res. 2019 Jan;98(1):91-97. doi: 10.1177/0022034518795673. Epub 2018 Sep 6.


SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.

Haddad E, Logan BR, Griffith LM, Buckley RH, Parrott RE, Prockop SE, Small TN, Chaisson J, Dvorak CC, Murnane M, Kapoor N, Abdel-Azim H, Hanson IC, Martinez C, Bleesing JJH, Chandra S, Smith AR, Cavanaugh ME, Jyonouchi S, Sullivan KE, Burroughs L, Skoda-Smith S, Haight AE, Tumlin AG, Quigg TC, Taylor C, Dávila Saldaña BJ, Keller MD, Seroogy CM, Desantes KB, Petrovic A, Leiding JW, Shyr DC, Decaluwe H, Teira P, Gillio AP, Knutsen AP, Moore TB, Kletzel M, Craddock JA, Aquino V, Davis JH, Yu LC, Cuvelier GDE, Bednarski JJ, Goldman FD, Kang EM, Shereck E, Porteus MH, Connelly JA, Fleisher TA, Malech HL, Shearer WT, Szabolcs P, Thakar MS, Vander Lugt MT, Heimall J, Yin Z, Pulsipher MA, Pai SY, Kohn DB, Puck JM, Cowan MJ, O'Reilly RJ, Notarangelo LD.

Blood. 2018 Oct 25;132(17):1737-1749. doi: 10.1182/blood-2018-03-840702. Epub 2018 Aug 28.


Bernese periacetabular osteotomy through a double approach : Simplification of a surgical technique.

Dienst M, Goebel L, Birk S, Kohn D.

Oper Orthop Traumatol. 2018 Oct;30(5):342-358. doi: 10.1007/s00064-018-0554-8. Epub 2018 Aug 10. Review.


Polyyne formation via skeletal rearrangement induced by atomic manipulation.

Pavliček N, Gawel P, Kohn DR, Majzik Z, Xiong Y, Meyer G, Anderson HL, Gross L.

Nat Chem. 2018 Aug;10(8):853-858. doi: 10.1038/s41557-018-0067-y. Epub 2018 Jul 2.


Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome.

Kuo CY, Long JD, Campo-Fernandez B, de Oliveira S, Cooper AR, Romero Z, Hoban MD, Joglekar AV, Lill GR, Kaufman ML, Fitz-Gibbon S, Wang X, Hollis RP, Kohn DB.

Cell Rep. 2018 May 29;23(9):2606-2616. doi: 10.1016/j.celrep.2018.04.103.


B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation.

Miggelbrink AM, Logan BR, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, Abdel-Azim H, Prockop SE, Shyr D, Decaluwe H, Hanson IC, Gillio A, Dávila Saldaña BJ, Eibel H, Hopkins G, Walter JE, Whangbo JS, Kohn DB, Puck JM, Cowan MJ, Griffith LM, Haddad E, O'Reilly RJ, Notarangelo LD, Pai SY.

Blood. 2018 Jun 28;131(26):2967-2977. doi: 10.1182/blood-2017-10-809822. Epub 2018 May 4.


Dental, Oral, and Craniofacial Regenerative Medicine: Transforming Biotechnologies for Innovating Patient Care.

Giannobile WV, Chai Y, Chen Y, Healy KE, Klein O, Lane N, Longaker MT, Lotz JC, Mooney DJ, Sfeir CS, Urata M, Wagner WR, Wu BM, Kohn DH.

J Dent Res. 2018 Apr;97(4):361-363. doi: 10.1177/0022034518761346. No abstract available.


Structural Failure of a Modern Knee Tumor Megaendoprosthesis.

Koch K, Kohn D, Anagnostakos K.

Case Rep Orthop. 2017;2017:2429459. doi: 10.1155/2017/2429459. Epub 2017 Dec 21.


Efficacy of vildagliptin for prevention of postpartum diabetes in women with a recent history of insulin-requiring gestational diabetes: A phase II, randomized, double-blind, placebo-controlled study.

Hummel S, Beyerlein A, Pfirrmann M, Hofelich A, Much D, Hivner S, Bunk M, Herbst M, Peplow C, Walter M, Kohn D, Hummel N, Kratzsch J, Hummel M, Füchtenbusch M, Hasford J, Ziegler AG; PINGUIN Study Group.

Mol Metab. 2018 Mar;9:168-175. doi: 10.1016/j.molmet.2017.12.015. Epub 2018 Jan 3.


Leukocyte adhesion deficiency-I: A comprehensive review of all published cases.

Almarza Novoa E, Kasbekar S, Thrasher AJ, Kohn DB, Sevilla J, Nguyen T, Schwartz JD, Bueren JA.

J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1418-1420.e10. doi: 10.1016/j.jaip.2017.12.008. Epub 2018 Jan 20. No abstract available.


[Orthopaedics and the law].

Ewerbeck V, Kohn D, Ehlenbeck S.

Orthopade. 2018 Feb;47(2):87-88. doi: 10.1007/s00132-018-3530-y. German. No abstract available.


Synthesis of Polyynes Using Dicobalt Masking Groups.

Kohn DR, Gawel P, Xiong Y, Christensen KE, Anderson HL.

J Org Chem. 2018 Feb 16;83(4):2077-2086. doi: 10.1021/acs.joc.7b03015. Epub 2018 Feb 7.


Gene therapy comes of age.

Dunbar CE, High KA, Joung JK, Kohn DB, Ozawa K, Sadelain M.

Science. 2018 Jan 12;359(6372). pii: eaan4672. doi: 10.1126/science.aan4672. Review.


Medial Patellofemoral Ligament Reconstruction: Impact of Knee Flexion Angle During Graft Fixation on Dynamic Patellofemoral Contact Pressure-A Biomechanical Study.

Lorbach O, Zumbansen N, Kieb M, Efe T, Pizanis A, Kohn D, Haupert A.

Arthroscopy. 2018 Apr;34(4):1072-1082. doi: 10.1016/j.arthro.2017.09.047. Epub 2018 Jan 2.


Characterization of Gene Alterations following Editing of the β-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells.

Long J, Hoban MD, Cooper AR, Kaufman ML, Kuo CY, Campo-Fernandez B, Lumaquin D, Hollis RP, Wang X, Kohn DB, Romero Z.

Mol Ther. 2018 Feb 7;26(2):468-479. doi: 10.1016/j.ymthe.2017.11.001. Epub 2017 Nov 9.


Bone morphogenetic protein signaling through ACVR1 and BMPR1A negatively regulates bone mass along with alterations in bone composition.

Shi C, Mandair GS, Zhang H, Vanrenterghem GG, Ridella R, Takahashi A, Zhang Y, Kohn DH, Morris MD, Mishina Y, Sun H.

J Struct Biol. 2018 Mar;201(3):237-246. doi: 10.1016/j.jsb.2017.11.010. Epub 2017 Nov 23.


Hematopoietic Stem Cell Gene Therapy: Progress and Lessons Learned.

Morgan RA, Gray D, Lomova A, Kohn DB.

Cell Stem Cell. 2017 Nov 2;21(5):574-590. doi: 10.1016/j.stem.2017.10.010. Review.


Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study.

Heimall J, Logan BR, Cowan MJ, Notarangelo LD, Griffith LM, Puck JM, Kohn DB, Pulsipher MA, Parikh S, Martinez C, Kapoor N, O'Reilly R, Boyer M, Pai SY, Goldman F, Burroughs L, Chandra S, Kletzel M, Thakar M, Connelly J, Cuvelier G, Davila Saldana BJ, Shereck E, Knutsen A, Sullivan KE, DeSantes K, Gillio A, Haddad E, Petrovic A, Quigg T, Smith AR, Stenger E, Yin Z, Shearer WT, Fleisher T, Buckley RH, Dvorak CC.

Blood. 2017 Dec 21;130(25):2718-2727. doi: 10.1182/blood-2017-05-781849. Epub 2017 Oct 11.


Longitudinale Sehnenspreizung in Kombination mit Unterdrucktherapie zur Therapie freiliegender Achillessehnen.

Wetzig T, Kohn D.

J Dtsch Dermatol Ges. 2017 Oct;15(10):1050-1052. doi: 10.1111/ddg.13334_g. No abstract available.


Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.

Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS.

Stem Cell Res Ther. 2017 Oct 2;8(1):217. doi: 10.1186/s13287-017-0652-9. Erratum in: Stem Cell Res Ther. 2019 Feb 12;10(1):52.

Supplemental Content

Support Center