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Risk Assessment and Regulation of Plants Modified by Modern Biotechniques: Current Status and Future Challenges.

Schiemann J, Dietz-Pfeilstetter A, Hartung F, Kohl C, Romeis J, Sprink T.

Annu Rev Plant Biol. 2019 Apr 29;70:699-726. doi: 10.1146/annurev-arplant-050718-100025. Epub 2019 Mar 1.


PAIPline: pathogen identification in metagenomic and clinical next generation sequencing samples.

Andrusch A, Dabrowski PW, Klenner J, Tausch SH, Kohl C, Osman AA, Renard BY, Nitsche A.

Bioinformatics. 2018 Sep 1;34(17):i715-i721. doi: 10.1093/bioinformatics/bty595.


The Neurodynamic Decision Variable in Human Multi-alternative Perceptual Choice.

Kohl C, Spieser L, Forster B, Bestmann S, Yarrow K.

J Cogn Neurosci. 2019 Feb;31(2):262-277. doi: 10.1162/jocn_a_01347. Epub 2018 Oct 2.


Laser-assisted photodynamic therapy for actinic keratosis: A systematic review and meta-analysis.

Steeb T, Schlager JG, Kohl C, Ruzicka T, Heppt MV, Berking C.

J Am Acad Dermatol. 2019 Apr;80(4):947-956. doi: 10.1016/j.jaad.2018.09.021. Epub 2018 Sep 27.


Tissue-Based Universal Virus Detection (TUViD-VM) Protocol for Viral Metagenomics.

Kohl C, Kurth A.

Methods Mol Biol. 2018;1838:15-23. doi: 10.1007/978-1-4939-8682-8_2.


Neurodynamic Evidence Supports a Forced-Excursion Model of Decision-Making under Speed/Accuracy Instructions.

Spieser L, Kohl C, Forster B, Bestmann S, Yarrow K.

eNeuro. 2018 Jun 26;5(3). pii: ENEURO.0159-18.2018. doi: 10.1523/ENEURO.0159-18.2018. eCollection 2018 May-Jun.


Humoral and cellular immune response in Wistar Han RCC rats fed two genetically modified maize MON810 varieties for 90 days (EU 7th Framework Programme project GRACE).

Tulinská J, Adel-Patient K, Bernard H, Líšková A, Kuricová M, Ilavská S, Horváthová M, Kebis A, Rollerová E, Babincová J, Aláčová R, Wal JM, Schmidt K, Schmidtke J, Schmidt P, Kohl C, Wilhelm R, Schiemann J, Steinberg P.

Arch Toxicol. 2018 Jul;92(7):2385-2399. doi: 10.1007/s00204-018-2230-z. Epub 2018 May 31.


Hervey virus: Study on co-circulation with Henipaviruses in Pteropid bats within their distribution range from Australia to Africa.

Kohl C, Tachedjian M, Todd S, Monaghan P, Boyd V, Marsh GA, Crameri G, Field H, Kurth A, Smith I, Wang LF.

PLoS One. 2018 Feb 1;13(2):e0191933. doi: 10.1371/journal.pone.0191933. eCollection 2018.


Cenerimod, a novel selective S1P1 receptor modulator with unique signaling properties.

Piali L, Birker-Robaczewska M, Lescop C, Froidevaux S, Schmitz N, Morrison K, Kohl C, Rey M, Studer R, Vezzali E, Hess P, Clozel M, Steiner B, Bolli MH, Nayler O.

Pharmacol Res Perspect. 2017 Dec;5(6). doi: 10.1002/prp2.370.


S1P1 Modulator-Induced G αi Signaling and β-Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In Vivo.

Birker-Robaczewska M, Bolli M, Rey M, de Kanter R, Kohl C, Lescop C, Boucher M, Poirey S, Steiner B, Nayler O.

Mol Pharmacol. 2018 Feb;93(2):109-118. doi: 10.1124/mol.117.109140. Epub 2017 Dec 4.


Use of RNALater® Preservation for Virome Sequencing in Outbreak Settings.

Kohl C, Wegener M, Nitsche A, Kurth A.

Front Microbiol. 2017 Sep 26;8:1888. doi: 10.3389/fmicb.2017.01888. eCollection 2017.


Quality Requirements for Electronic Health Record Systems*. A Japanese-German Information Management Perspective.

Winter A, Takabayashi K, Jahn F, Kimura E, Engelbrecht R, Haux R, Honda M, Hübner UH, Inoue S, Kohl CD, Matsumoto T, Matsumura Y, Miyo K, Nakashima N, Prokosch HU, Staemmler M.

Methods Inf Med. 2017 Aug 7;56(7):e92-e104. doi: 10.3414/ME17-05-0002.


Comparing Viral Metagenomic Extraction Methods.

Klenner J, Kohl C, Dabrowski PW, Nitsche A.

Curr Issues Mol Biol. 2017;24:59-70. doi: 10.21775/cimb.024.059. Epub 2017 Jul 6.


Letter to the Editor, Physiologically based pharmacokinetic predictions of intestinal BCRP-mediated effect of telmisartan on the pharmacokinetics of rosuvastatin in humans.

de Kanter R, Kohl C.

Biopharm Drug Dispos. 2017 Oct;38(7):443-444. doi: 10.1002/bdd.2079. Epub 2017 Jun 28. No abstract available.


Synthesis and Characterization of Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Antibacterial Activity against Gram-Negative Bacteria.

Surivet JP, Zumbrunn C, Bruyère T, Bur D, Kohl C, Locher HH, Seiler P, Ertel EA, Hess P, Enderlin-Paput M, Enderlin-Paput S, Gauvin JC, Mirre A, Hubschwerlen C, Ritz D, Rueedi G.

J Med Chem. 2017 May 11;60(9):3776-3794. doi: 10.1021/acs.jmedchem.6b01831. Epub 2017 Apr 24.


Including non-public data and studies in systematic reviews and systematic maps.

Haddaway NR, Collins AM, Coughlin D, Kohl C.

Environ Int. 2017 Feb;99:351-355. doi: 10.1016/j.envint.2016.12.003. Epub 2016 Dec 7.


Viral Metagenomics on Blood-Feeding Arthropods as a Tool for Human Disease Surveillance.

Brinkmann A, Nitsche A, Kohl C.

Int J Mol Sci. 2016 Oct 19;17(10). pii: E1743. Review.


Variability of control data and relevance of observed group differences in five oral toxicity studies with genetically modified maize MON810 in rats.

Schmidt K, Schmidtke J, Schmidt P, Kohl C, Wilhelm R, Schiemann J, van der Voet H, Steinberg P.

Arch Toxicol. 2017 Apr;91(4):1977-2006. doi: 10.1007/s00204-016-1857-x. Epub 2016 Oct 11.


Letter in response to the letter to the editor of archives of toxicology by Woegerbauer et al. (2016).

Wilhelm R, Kohl C, Schiemann J, Steinberg P.

Arch Toxicol. 2016 Dec;90(12):3133-3137. Epub 2016 Oct 5. No abstract available.


Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015.

Kerber R, Krumkamp R, Diallo B, Jaeger A, Rudolf M, Lanini S, Bore JA, Koundouno FR, Becker-Ziaja B, Fleischmann E, Stoecker K, Meschi S, Mély S, Newman EN, Carletti F, Portmann J, Korva M, Wolff S, Molkenthin P, Kis Z, Kelterbaum A, Bocquin A, Strecker T, Fizet A, Castilletti C, Schudt G, Ottowell L, Kurth A, Atkinson B, Badusche M, Cannas A, Pallasch E, Bosworth A, Yue C, Pályi B, Ellerbrok H, Kohl C, Oestereich L, Logue CH, Lüdtke A, Richter M, Ngabo D, Borremans B, Becker D, Gryseels S, Abdellati S, Vermoesen T, Kuisma E, Kraus A, Liedigk B, Maes P, Thom R, Duraffour S, Diederich S, Hinzmann J, Afrough B, Repits J, Mertens M, Vitoriano I, Bah A, Sachse A, Boettcher JP, Wurr S, Bockholt S, Nitsche A, Županc TA, Strasser M, Ippolito G, Becker S, Raoul H, Carroll MW, De Clerck H, Van Herp M, Sprecher A, Koivogui L, Magassouba N, Keïta S, Drury P, Gurry C, Formenty P, May J, Gabriel M, Wölfel R, Günther S, Di Caro A.

J Infect Dis. 2016 Oct 15;214(suppl 3):S250-S257. Epub 2016 Sep 16.


Indications for liver transplantation in adults : Recommendations of the Austrian Society for Gastroenterology and Hepatology (ÖGGH) in cooperation with the Austrian Society for Transplantation, Transfusion and Genetics (ATX).

Graziadei I, Zoller H, Fickert P, Schneeberger S, Finkenstedt A, Peck-Radosavljevic M, Müller H, Kohl C, Sperner-Unterweger B, Eschertzhuber S, Hofer H, Öfner D, Tilg H, Vogel W, Trauner M, Berlakovich G.

Wien Klin Wochenschr. 2016 Oct;128(19-20):679-690. Epub 2016 Sep 2.


One-year oral toxicity study on a genetically modified maize MON810 variety in Wistar Han RCC rats (EU 7th Framework Programme project GRACE).

Zeljenková D, Aláčová R, Ondrejková J, Ambrušová K, Bartušová M, Kebis A, Kovrižnych J, Rollerová E, Szabová E, Wimmerová S, Černák M, Krivošíková Z, Kuricová M, Líšková A, Spustová V, Tulinská J, Levkut M, Révajová V, Ševčíková Z, Schmidt K, Schmidtke J, Schmidt P, La Paz JL, Corujo M, Pla M, Kleter GA, Kok EJ, Sharbati J, Bohmer M, Bohmer N, Einspanier R, Adel-Patient K, Spök A, Pöting A, Kohl C, Wilhelm R, Schiemann J, Steinberg P.

Arch Toxicol. 2016 Oct;90(10):2531-62. doi: 10.1007/s00204-016-1798-4. Epub 2016 Jul 20.


Proposed criteria for the evaluation of the scientific quality of mandatory rat and mouse feeding trials with whole food/feed derived from genetically modified plants.

Schmidt K, Döhring J, Kohl C, Pla M, Kok EJ, Glandorf DCM, Custers R, van der Voet H, Sharbati J, Einspanier R, Zeljenková D, Tulinská J, Spök A, Alison C, Schrenk D, Pöting A, Wilhelm R, Schiemann J, Steinberg P.

Arch Toxicol. 2016 Sep;90(9):2287-2291. doi: 10.1007/s00204-016-1762-3. Epub 2016 Jun 21. No abstract available.


An RNA-dependent RNA polymerase gene in bat genomes derived from an ancient negative-strand RNA virus.

Horie M, Kobayashi Y, Honda T, Fujino K, Akasaka T, Kohl C, Wibbelt G, Mühldorfer K, Kurth A, Müller MA, Corman VM, Gillich N, Suzuki Y, Schwemmle M, Tomonaga K.

Sci Rep. 2016 May 13;6:25873. doi: 10.1038/srep25873.


Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups.

Lescop C, Müller C, Mathys B, Birker M, de Kanter R, Kohl C, Hess P, Nayler O, Rey M, Sieber P, Steiner B, Weller T, Bolli MH.

Eur J Med Chem. 2016 Jun 30;116:222-238. doi: 10.1016/j.ejmech.2016.03.048. Epub 2016 Mar 23.


In Vivo Pharmacodynamic Target Investigation of Two Bacterial Topoisomerase Inhibitors, ACT-387042 and ACT-292706, in the Neutropenic Murine Thigh Model against Streptococcus pneumoniae and Staphylococcus aureus.

Lepak AJ, Seiler P, Surivet JP, Ritz D, Kohl C, Andes DR.

Antimicrob Agents Chemother. 2016 May 23;60(6):3626-32. doi: 10.1128/AAC.00363-16. Print 2016 Jun.


Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.

Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B.

Eur J Med Chem. 2016 Jun 10;115:326-41. doi: 10.1016/j.ejmech.2016.03.020. Epub 2016 Mar 12.


Random sampling of the Central European bat fauna reveals the existence of numerous hitherto unknown adenoviruses.

Vidovszky M, Kohl C, Boldogh S, Görföl T, Wibbelt G, Kurth A, Harrach B.

Acta Vet Hung. 2015 Dec;63(4):508-25. doi: 10.1556/004.2015.047.


Physiologically-Based Pharmacokinetic Modeling of Macitentan: Prediction of Drug-Drug Interactions.

de Kanter R, Sidharta PN, Delahaye S, Gnerre C, Segrestaa J, Buchmann S, Kohl C, Treiber A.

Clin Pharmacokinet. 2016 Mar;55(3):369-80. doi: 10.1007/s40262-015-0322-y.


Can Systematic Reviews Inform GMO Risk Assessment and Risk Management?

Kohl C, Frampton G, Sweet J, Spök A, Haddaway NR, Wilhelm R, Unger S, Schiemann J.

Front Bioeng Biotechnol. 2015 Aug 12;3:113. doi: 10.3389/fbioe.2015.00113. eCollection 2015.


Integrating data from multiple sources for data completeness in a web-based registry for pediatric renal transplantation--the CERTAIN Registry.

Köster L, Krupka K, Höcker B, Rahmel A, Samuel U, Zanen W, Opelz G, Süsal C, Döhler B, Plotnicki L, Kohl CD, Knaup P, Tönshoff B.

Stud Health Technol Inform. 2015;216:1049.


Levels in neurotransmitter precursor amino acids correlate with mental health in patients with breast cancer.

Hüfner K, Oberguggenberger A, Kohl C, Geisler S, Gamper E, Meraner V, Egeter J, Hubalek M, Beer B, Fuchs D, Sperner-Unterweger B.

Psychoneuroendocrinology. 2015 Oct;60:28-38. doi: 10.1016/j.psyneuen.2015.06.001. Epub 2015 Jun 8.


Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa.

Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G, Rambaut A, Hewson R, García-Dorival I, Bore JA, Koundouno R, Abdellati S, Afrough B, Aiyepada J, Akhilomen P, Asogun D, Atkinson B, Badusche M, Bah A, Bate S, Baumann J, Becker D, Becker-Ziaja B, Bocquin A, Borremans B, Bosworth A, Boettcher JP, Cannas A, Carletti F, Castilletti C, Clark S, Colavita F, Diederich S, Donatus A, Duraffour S, Ehichioya D, Ellerbrok H, Fernandez-Garcia MD, Fizet A, Fleischmann E, Gryseels S, Hermelink A, Hinzmann J, Hopf-Guevara U, Ighodalo Y, Jameson L, Kelterbaum A, Kis Z, Kloth S, Kohl C, Korva M, Kraus A, Kuisma E, Kurth A, Liedigk B, Logue CH, Lüdtke A, Maes P, McCowen J, Mély S, Mertens M, Meschi S, Meyer B, Michel J, Molkenthin P, Muñoz-Fontela C, Muth D, Newman EN, Ngabo D, Oestereich L, Okosun J, Olokor T, Omiunu R, Omomoh E, Pallasch E, Pályi B, Portmann J, Pottage T, Pratt C, Priesnitz S, Quartu S, Rappe J, Repits J, Richter M, Rudolf M, Sachse A, Schmidt KM, Schudt G, Strecker T, Thom R, Thomas S, Tobin E, Tolley H, Trautner J, Vermoesen T, Vitoriano I, Wagner M, Wolff S, Yue C, Capobianchi MR, Kretschmer B, Hall Y, Kenny JG, Rickett NY, Dudas G, Coltart CE, Kerber R, Steer D, Wright C, Senyah F, Keita S, Drury P, Diallo B, de Clerck H, Van Herp M, Sprecher A, Traore A, Diakite M, Konde MK, Koivogui L, Magassouba N, Avšič-Županc T, Nitsche A, Strasser M, Ippolito G, Becker S, Stoecker K, Gabriel M, Raoul H, Di Caro A, Wölfel R, Formenty P, Günther S.

Nature. 2015 Aug 6;524(7563):97-101. doi: 10.1038/nature14594. Epub 2015 Jun 17.


Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice.

Kohl C, Wang XD, Grosse J, Fournier C, Harbich D, Westerholz S, Li JT, Bacq A, Sippel C, Hausch F, Sandi C, Schmidt MV.

Psychoneuroendocrinology. 2015 May;55:128-43. doi: 10.1016/j.psyneuen.2015.02.016. Epub 2015 Feb 26.


Enhancing the interpretation of statistical P values in toxicology studies: implementation of linear mixed models (LMMs) and standardized effect sizes (SESs).

Schmidt K, Schmidtke J, Kohl C, Wilhelm R, Schiemann J, van der Voet H, Steinberg P.

Arch Toxicol. 2016 Mar;90(3):731-51. doi: 10.1007/s00204-015-1487-8. Epub 2015 Feb 28.


Protocol for metagenomic virus detection in clinical specimens.

Kohl C, Brinkmann A, Dabrowski PW, Radonić A, Nitsche A, Kurth A.

Emerg Infect Dis. 2015 Jan;21(1):48-57. doi: 10.3201/eid2101.140766.


Geochemical niches of iron-oxidizing acidophiles in acidic coal mine drainage.

Jones DS, Kohl C, Grettenberger C, Larson LN, Burgos WD, Macaladya JL.

Appl Environ Microbiol. 2015 Feb;81(4):1242-50.


Novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram positive activity and improved safety profile.

Surivet JP, Zumbrunn C, Rueedi G, Bur D, Bruyère T, Locher H, Ritz D, Seiler P, Kohl C, Ertel EA, Hess P, Gauvin JC, Mirre A, Kaegi V, Dos Santos M, Kraemer S, Gaertner M, Delers J, Enderlin-Paput M, Weiss M, Sube R, Hadana H, Keck W, Hubschwerlen C.

J Med Chem. 2015 Jan 22;58(2):927-42. doi: 10.1021/jm501590q. Epub 2014 Dec 23.


Homer1/mGluR5 activity moderates vulnerability to chronic social stress.

Wagner KV, Hartmann J, Labermaier C, Häusl AS, Zhao G, Harbich D, Schmid B, Wang XD, Santarelli S, Kohl C, Gassen NC, Matosin N, Schieven M, Webhofer C, Turck CW, Lindemann L, Jaschke G, Wettstein JG, Rein T, Müller MB, Schmidt MV.

Neuropsychopharmacology. 2015 Mar 13;40(5):1222-33. doi: 10.1038/npp.2014.308.


Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE).

Zeljenková D, Ambrušová K, Bartušová M, Kebis A, Kovrižnych J, Krivošíková Z, Kuricová M, Líšková A, Rollerová E, Spustová V, Szabová E, Tulinská J, Wimmerová S, Levkut M, Révajová V, Ševčíková Z, Schmidt K, Schmidtke J, La Paz JL, Corujo M, Pla M, Kleter GA, Kok EJ, Sharbati J, Hanisch C, Einspanier R, Adel-Patient K, Wal JM, Spök A, Pöting A, Kohl C, Wilhelm R, Schiemann J, Steinberg P.

Arch Toxicol. 2014 Dec;88(12):2289-314. doi: 10.1007/s00204-014-1374-8. Epub 2014 Oct 2.


A framework for integrating heterogeneous clinical data for a disease area into a central data warehouse.

Karmen C, Ganzinger M, Kohl CD, Firnkorn D, Knaup-Gregori P.

Stud Health Technol Inform. 2014;205:1060-4.


European bats as carriers of viruses with zoonotic potential.

Kohl C, Kurth A.

Viruses. 2014 Aug 13;6(8):3110-28. doi: 10.3390/v6083110. Review.


Strontium isotopes test long-term zonal isolation of injected and Marcellus formation water after hydraulic fracturing.

Kohl CA, Capo RC, Stewart BW, Wall AJ, Schroeder KT, Hammack RW, Guthrie GD.

Environ Sci Technol. 2014 Aug 19;48(16):9867-73. doi: 10.1021/es501099k. Epub 2014 Jul 28.


Accuracy of chemical shift MR imaging in diagnosing indeterminate bone marrow lesions in the pelvis: review of a single institution's experience.

Kohl CA, Chivers FS, Lorans R, Roberts CC, Kransdorf MJ.

Skeletal Radiol. 2014 Aug;43(8):1079-84. doi: 10.1007/s00256-014-1886-6. Epub 2014 Apr 30.


A polymorphism in the Crhr1 gene determines stress vulnerability in male mice.

Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, Jones KA, Müller MB, Uhr M, Holsboer F, Binder EB, Schmidt MV.

Endocrinology. 2014 Jul;155(7):2500-10. doi: 10.1210/en.2013-1986. Epub 2014 Apr 28.


Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.

Bolli MH, Abele S, Birker M, Bravo R, Bur D, de Kanter R, Kohl C, Grimont J, Hess P, Lescop C, Mathys B, Müller C, Nayler O, Rey M, Scherz M, Schmidt G, Seifert J, Steiner B, Velker J, Weller T.

J Med Chem. 2014 Jan 9;57(1):110-30. doi: 10.1021/jm4014696. Epub 2013 Dec 24.


Novel S1P(1) receptor agonists--part 2: from bicyclo[3.1.0]hexane-fused thiophenes to isobutyl substituted thiophenes.

Bolli MH, Velker J, Müller C, Mathys B, Birker M, Bravo R, Bur D, de Kanter R, Hess P, Kohl C, Lehmann D, Meyer S, Nayler O, Rey M, Scherz M, Steiner B.

J Med Chem. 2014 Jan 9;57(1):78-97. doi: 10.1021/jm401456d. Epub 2013 Dec 17.


Novel S1P1 receptor agonists--part 1: From pyrazoles to thiophenes.

Bolli MH, Müller C, Mathys B, Abele S, Birker M, Bravo R, Bur D, Hess P, Kohl C, Lehmann D, Nayler O, Rey M, Meyer S, Scherz M, Schmidt G, Steiner B, Treiber A, Velker J, Weller T.

J Med Chem. 2013 Dec 12;56(23):9737-55. doi: 10.1021/jm4014373. Epub 2013 Nov 22.


Distress in primary caregivers and patients listed for liver transplantation.

Malik P, Kohl C, Holzner B, Kemmler G, Graziadei I, Vogel W, Sperner-Unterweger B.

Psychiatry Res. 2014 Jan 30;215(1):159-62. doi: 10.1016/j.psychres.2013.08.046. Epub 2013 Nov 7.


On the seamless, harmonized use of ISO/IEEE11073 and openEHR.

Trigo JD, Kohl CD, Eguzkiza A, Martínez-Espronceda M, Alesanco Á, Serrano L, García J, Knaup P.

IEEE J Biomed Health Inform. 2014 May;18(3):872-84. doi: 10.1109/JBHI.2013.2285441. Epub 2013 Oct 10.


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