Sort by
Items per page

Send to

Choose Destination

Search results

Items: 31


An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity.

Krzysiak TC, Thomas L, Choi YJ, Auclair S, Qian Y, Luan S, Krasnow SM, Thomas LL, Koharudin LMI, Benos PV, Marks DL, Gronenborn AM, Thomas G.

Mol Cell. 2018 Dec 20;72(6):985-998.e7. doi: 10.1016/j.molcel.2018.10.007. Epub 2018 Nov 8.


Determination of accurate backbone chemical shift tensors in microcrystalline proteins by integrating MAS NMR and QM/MM.

Fritz M, Quinn CM, Wang M, Hou G, Lu X, Koharudin LMI, Struppe J, Case DA, Polenova T, Gronenborn AM.

Phys Chem Chem Phys. 2018 Apr 4;20(14):9543-9553. doi: 10.1039/c8cp00647d.


Integrating NMR, SAXS, and Atomistic Simulations: Structure and Dynamics of a Two-Domain Protein.

Debiec KT, Whitley MJ, Koharudin LMI, Chong LT, Gronenborn AM.

Biophys J. 2018 Feb 27;114(4):839-855. doi: 10.1016/j.bpj.2018.01.001.


Toward Closing the Gap: Quantum Mechanical Calculations and Experimentally Measured Chemical Shifts of a Microcrystalline Lectin.

Fritz M, Quinn CM, Wang M, Hou G, Lu X, Koharudin LMI, Polenova T, Gronenborn AM.

J Phys Chem B. 2017 Apr 20;121(15):3574-3585. doi: 10.1021/acs.jpcb.6b09479. Epub 2016 Dec 21.


Structural Insight into Fungal Cell Wall Recognition by a CVNH Protein with a Single LysM Domain.

Koharudin LM, Debiec KT, Gronenborn AM.

Structure. 2015 Nov 3;23(11):2143-54. doi: 10.1016/j.str.2015.07.023. Epub 2015 Oct 9.


Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.

Wu Y, Koharudin LM, Mehrens J, DeLucia M, Byeon CH, Byeon IJ, Calero G, Ahn J, Gronenborn AM.

J Biol Chem. 2015 Jul 17;290(29):17935-45. doi: 10.1074/jbc.M115.665513. Epub 2015 Jun 4.


Sampling of Glycan-Bound Conformers by the Anti-HIV Lectin Oscillatoria agardhii agglutinin in the Absence of Sugar.

Carneiro MG, Koharudin LM, Ban D, Sabo TM, Trigo-Mourino P, Mazur A, Griesinger C, Gronenborn AM, Lee D.

Angew Chem Int Ed Engl. 2015 May 26;54(22):6462-5. doi: 10.1002/anie.201500213. Epub 2015 Apr 14.


(1)H, (13)C and (15)N resonance assignment of the anti-HIV lectin from Oscillatoria agardhii.

Carneiro MG, Koharudin LM, Griesinger C, Gronenborn AM, Lee D.

Biomol NMR Assign. 2015 Oct;9(2):317-9. doi: 10.1007/s12104-015-9600-8. Epub 2015 Feb 14.


Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.

Koharudin LM, Wu Y, DeLucia M, Mehrens J, Gronenborn AM, Ahn J.

J Biol Chem. 2014 Nov 21;289(47):32617-27. doi: 10.1074/jbc.M114.591958. Epub 2014 Oct 6.


Antiviral lectins as potential HIV microbicides.

Koharudin LM, Gronenborn AM.

Curr Opin Virol. 2014 Aug;7:95-100. doi: 10.1016/j.coviro.2014.05.006. Epub 2014 Jul 8. Review.


Broad anti-HIV activity of the Oscillatoria agardhii agglutinin homologue lectin family.

Férir G, Huskens D, Noppen S, Koharudin LM, Gronenborn AM, Schols D.

J Antimicrob Chemother. 2014 Oct;69(10):2746-58. doi: 10.1093/jac/dku220. Epub 2014 Jun 25.


Enhanced accuracy of kinetic information from CT-CPMG experiments by transverse rotating-frame spectroscopy.

Ban D, Mazur A, Carneiro MG, Sabo TM, Giller K, Koharudin LM, Becker S, Gronenborn AM, Griesinger C, Lee D.

J Biomol NMR. 2013 Sep;57(1):73-82. doi: 10.1007/s10858-013-9769-z. Epub 2013 Aug 15.


Crystal structure of the cataract-causing P23T γD-crystallin mutant.

Ji F, Koharudin LM, Jung J, Gronenborn AM.

Proteins. 2013 Sep;81(9):1493-8. doi: 10.1002/prot.24321. Epub 2013 Jun 17.


Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.

Koharudin LM, Liu L, Gronenborn AM.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7702-7. doi: 10.1073/pnas.1300327110. Epub 2013 Apr 22.


A NMR guided approach for CsrA-RNA crystallization.

Koharudin LM, Boelens R, Kaptein R, Gronenborn AM.

J Biomol NMR. 2013 May;56(1):31-9. doi: 10.1007/s10858-013-9712-3. Epub 2013 Jan 29.


The human W42R γD-crystallin mutant structure provides a link between congenital and age-related cataracts.

Ji F, Jung J, Koharudin LM, Gronenborn AM.

J Biol Chem. 2013 Jan 4;288(1):99-109. doi: 10.1074/jbc.M112.416354. Epub 2012 Nov 2.


Sweet entanglements--protein:glycan interactions in two HIV-inactivating lectin families.

Koharudin LM, Gronenborn AM.

Biopolymers. 2013 Mar;99(3):196-202. doi: 10.1002/bip.22106. Epub 2012 Sep 29. Review.


Structural insights into the anti-HIV activity of the Oscillatoria agardhii agglutinin homolog lectin family.

Koharudin LM, Kollipara S, Aiken C, Gronenborn AM.

J Biol Chem. 2012 Sep 28;287(40):33796-811. Epub 2012 Aug 4.


Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties.

Jayaraman M, Mishra R, Kodali R, Thakur AK, Koharudin LM, Gronenborn AM, Wetzel R.

Biochemistry. 2012 Apr 3;51(13):2706-16. doi: 10.1021/bi3000929. Epub 2012 Mar 20.


Structural and binding studies of the C-terminal domains of yeast TFIIF subunits Tfg1 and Tfg2.

Kilpatrick AM, Koharudin LM, Calero GA, Gronenborn AM.

Proteins. 2012 Feb;80(2):519-29. doi: 10.1002/prot.23217. Epub 2011 Nov 17.


Structural basis of the anti-HIV activity of the cyanobacterial Oscillatoria Agardhii agglutinin.

Koharudin LM, Gronenborn AM.

Structure. 2011 Aug 10;19(8):1170-81. doi: 10.1016/j.str.2011.05.010.


Structure-function analysis of a CVNH-LysM lectin expressed during plant infection by the rice blast fungus Magnaporthe oryzae.

Koharudin LM, Viscomi AR, Montanini B, Kershaw MJ, Talbot NJ, Ottonello S, Gronenborn AM.

Structure. 2011 May 11;19(5):662-74. doi: 10.1016/j.str.2011.03.004.


Novel fold and carbohydrate specificity of the potent anti-HIV cyanobacterial lectin from Oscillatoria agardhii.

Koharudin LM, Furey W, Gronenborn AM.

J Biol Chem. 2011 Jan 14;286(2):1588-97. doi: 10.1074/jbc.M110.173278. Epub 2010 Oct 19.


Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1.

Koharudin LM, Liu H, Di Maio R, Kodali RB, Graham SH, Gronenborn AM.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6835-40. doi: 10.1073/pnas.1002295107. Epub 2010 Mar 15.


A comparative analysis of the equilibrium dynamics of a designed protein inferred from NMR, X-ray, and computations.

Liu L, Koharudin LM, Gronenborn AM, Bahar I.

Proteins. 2009 Dec;77(4):927-39. doi: 10.1002/prot.22518.


A designed chimeric cyanovirin-N homolog lectin: structure and molecular basis of sucrose binding.

Koharudin LM, Furey W, Gronenborn AM.

Proteins. 2009 Dec;77(4):904-15. doi: 10.1002/prot.22514.


The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).

Koharudin LM, Furey W, Liu H, Liu YJ, Gronenborn AM.

J Biol Chem. 2009 Aug 28;284(35):23697-707. doi: 10.1074/jbc.M109.008995. Epub 2009 Jun 24.


The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.

Koharudin LM, Viscomi AR, Jee JG, Ottonello S, Gronenborn AM.

Structure. 2008 Apr;16(4):570-84. doi: 10.1016/j.str.2008.01.015.


Use of very long-distance NOEs in a fully deuterated protein: an approach for rapid protein fold determination.

Koharudin LM, Bonvin AM, Kaptein R, Boelens R.

J Magn Reson. 2003 Aug;163(2):228-35.


Supplemental Content

Loading ...
Support Center