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Items: 1 to 50 of 318

1.

MicroRNA-451a in extracellular, blood-resident vesicles attenuates macrophage and dendritic cell responses to influenza whole-virus vaccine.

Okamoto M, Fukushima Y, Kouwaki T, Daito T, Kohara M, Kida H, Oshiumi H.

J Biol Chem. 2018 Oct 3. pii: jbc.RA118.003862. doi: 10.1074/jbc.RA118.003862. [Epub ahead of print]

2.

A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-α2b.

Imada T, Moriya K, Uchiyama M, Inukai N, Hitotsuyanagi M, Masuda A, Suzuki T, Ayukawa S, Tagawa YI, Dohmae N, Kohara M, Yamamura M, Kiga D.

ACS Synth Biol. 2018 Nov 16;7(11):2537-2546. doi: 10.1021/acssynbio.8b00188. Epub 2018 Oct 26.

PMID:
30277749
3.

Origin of cancer-associated fibroblasts and tumor-associated macrophages in humans after sex-mismatched bone marrow transplantation.

Kurashige M, Kohara M, Ohshima K, Tahara S, Hori Y, Nojima S, Wada N, Ikeda JI, Miyamura K, Ito M, Morii E.

Commun Biol. 2018 Sep 3;1:131. doi: 10.1038/s42003-018-0137-0. eCollection 2018.

4.

A case of ectopic ACTH syndrome due to DDAVP-sensitive but V1b receptor-negative bronchial typical carcinoid with lymphatic metastasis and plasma ProGRP elevation.

Yamamuro T, Inoue K, Nagai Y, Azuma D, Yamamoto A, Hara K, Kohara M, Iwata T, Nakatsuka S, Morii E, Yamamoto T.

Endocr J. 2018 Sep 20. doi: 10.1507/endocrj.EJ18-0052. [Epub ahead of print]

5.

TIBIAL ADAMANTINOMA: ANALYSIS OF SEVEN CONSECUTIVE CASES IN A SINGLE INSTITUTION.

Zumárraga JP, Cartolano R, Kohara MT, Baptista AM, Dos Santos FG, de Camargo OP.

Acta Ortop Bras. 2018;26(4):252-254. doi: 10.1590/1413-785220182604192680.

6.

EXTRA-ABDOMINAL DESMOID TUMOR: ANALYSIS OF 23 CONSECUTIVE CASES IN A SINGLE INSTITUTION.

Zumárraga JP, Coimbra BGMM, Dos Santos FG, Baptista AM, Kohara MT, de Camargo OP.

Acta Ortop Bras. 2018;26(4):244-247. doi: 10.1590/1413-785220182604192681.

7.

Valacyclovir Neurotoxicity and Nephrotoxicity in an Elderly Patient Complicated by Hyponatremia.

Murakami T, Akimoto T, Okada M, Hishida E, Sugase T, Miki A, Kohara M, Yoshizawa H, Masuda T, Kobayashi T, Saito O, Muto S, Nagata D.

Drug Target Insights. 2018 Jun 25;12:1177392818782899. doi: 10.1177/1177392818782899. eCollection 2018.

8.

Experimental in vitro and in vivo systems for studying the innate immune response during dengue virus infections.

Kitab B, Kohara M, Tsukiyama-Kohara K.

Arch Virol. 2018 Jul;163(7):1717-1726. doi: 10.1007/s00705-018-3784-z. Epub 2018 Mar 8. Review.

PMID:
29520688
9.

Hepatitis C Virus: Viral Quasispecies and Genotypes.

Tsukiyama-Kohara K, Kohara M.

Int J Mol Sci. 2017 Dec 22;19(1). pii: E23. doi: 10.3390/ijms19010023. Review.

10.

Peritoneal Dialysis and Retroperitoneal Laparoscopic Radical Nephrectomy: A Favorable Experience With a Patient Complicated by Renal Cell Carcinoma.

Imai R, Akimoto T, Kimura T, Kohara M, Shimizu T, Oka K, Shuto M, Asakura M, Nagayama I, Takeda SI, Yagisawa T, Muto S, Nagata D.

Clin Med Insights Case Rep. 2017 Dec 10;10:1179547617746362. doi: 10.1177/1179547617746362. eCollection 2017.

11.

Broad-spectrum antiviral agents: secreted phospholipase A2 targets viral envelope lipid bilayers derived from the endoplasmic reticulum membrane.

Chen M, Aoki-Utsubo C, Kameoka M, Deng L, Terada Y, Kamitani W, Sato K, Koyanagi Y, Hijikata M, Shindo K, Noda T, Kohara M, Hotta H.

Sci Rep. 2017 Nov 21;7(1):15931. doi: 10.1038/s41598-017-16130-w.

12.

Investigating the hepatitis B virus life cycle using engineered reporter hepatitis B viruses.

Nishitsuji H, Harada K, Ujino S, Zhang J, Kohara M, Sugiyama M, Mizokami M, Shimotohno K.

Cancer Sci. 2018 Jan;109(1):241-249. doi: 10.1111/cas.13440. Epub 2017 Dec 7.

13.

Pleuroperitoneal Communication and Ovarian Cancer Complicating Peritoneal Dialysis: A Case Report of a Patient with End-Stage Kidney Disease.

Akimoto T, Yamazaki T, Kohara M, Nakagawa S, Kanai Y, Izawa S, Yamamoto H, Nakazawa E, Masuda T, Kobayashi T, Saito O, Muto S, Kusano E, Nagata D.

Clin Med Insights Case Rep. 2017 Oct 16;10:1179547617735818. doi: 10.1177/1179547617735818. eCollection 2017.

14.

Highly specific delivery of siRNA to hepatocytes circumvents endothelial cell-mediated lipid nanoparticle-associated toxicity leading to the safe and efficacious decrease in the hepatitis B virus.

Sato Y, Matsui H, Yamamoto N, Sato R, Munakata T, Kohara M, Harashima H.

J Control Release. 2017 Nov 28;266:216-225. doi: 10.1016/j.jconrel.2017.09.044. Epub 2017 Oct 3.

PMID:
28986168
15.

Efficacy of recombinant measles virus expressing highly pathogenic avian influenza virus (HPAIV) antigen against HPAIV infection in monkeys.

Fujiyuki T, Horie R, Yoneda M, Kuraishi T, Yasui F, Kwon HJ, Munekata K, Ikeda F, Hoshi M, Kiso Y, Omi M, Sato H, Kida H, Hattori S, Kohara M, Kai C.

Sci Rep. 2017 Sep 20;7(1):12017. doi: 10.1038/s41598-017-08326-x.

16.

Oxidative Stress and Immune Responses During Hepatitis C Virus Infection in Tupaia belangeri.

Kayesh MEH, Ezzikouri S, Sanada T, Chi H, Hayashi Y, Rebbani K, Kitab B, Matsuu A, Miyoshi N, Hishima T, Kohara M, Tsukiyama-Kohara K.

Sci Rep. 2017 Aug 29;7(1):9848. doi: 10.1038/s41598-017-10329-7.

17.

Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial.

Kimura K, Ikoma A, Shibakawa M, Shimoda S, Harada K, Saio M, Imamura J, Osawa Y, Kimura M, Nishikawa K, Okusaka T, Morita S, Inoue K, Kanto T, Todaka K, Nakanishi Y, Kohara M, Mizokami M.

EBioMedicine. 2017 Sep;23:79-87. doi: 10.1016/j.ebiom.2017.08.016. Epub 2017 Aug 19.

18.

Retroperitoneal Bleeding: An Experience During Prophylactic Anticoagulation in a Patient With Nephrotic Syndrome.

Okada M, Akimoto T, Kawamata M, Imai T, Hishida E, Kohara M, Miki A, Murakami T, Sugase T, Masuda T, Ono Y, Ueda Y, Saito O, Muto S, Nagata D.

Clin Med Insights Case Rep. 2017 Aug 1;10:1179547617723317. doi: 10.1177/1179547617723317. eCollection 2017.

19.

Efficient siRNA Delivery by Lipid Nanoparticles Modified with a Nonstandard Macrocyclic Peptide for EpCAM-Targeting.

Sakurai Y, Mizumura W, Murata M, Hada T, Yamamoto S, Ito K, Iwasaki K, Katoh T, Goto Y, Takagi A, Kohara M, Suga H, Harashima H.

Mol Pharm. 2017 Oct 2;14(10):3290-3298. doi: 10.1021/acs.molpharmaceut.7b00362. Epub 2017 Aug 25.

PMID:
28789523
20.

Association between circulating fibroblast growth factor 21 and mortality in end-stage renal disease.

Kohara M, Masuda T, Shiizaki K, Akimoto T, Watanabe Y, Honma S, Sekiguchi C, Miyazawa Y, Kusano E, Kanda Y, Asano Y, Kuro-O M, Nagata D.

PLoS One. 2017 Jun 5;12(6):e0178971. doi: 10.1371/journal.pone.0178971. eCollection 2017.

21.

Transcription factor FOXO1 promotes cell migration toward exogenous ATP via controlling P2Y1 receptor expression in lymphatic endothelial cells.

Niimi K, Ueda M, Fukumoto M, Kohara M, Sawano T, Tsuchihashi R, Shibata S, Inagaki S, Furuyama T.

Biochem Biophys Res Commun. 2017 Aug 5;489(4):413-419. doi: 10.1016/j.bbrc.2017.05.156. Epub 2017 May 27.

PMID:
28559138
22.

Interferon-β response is impaired by hepatitis B virus infection in Tupaia belangeri.

Kayesh MEH, Ezzikouri S, Chi H, Sanada T, Yamamoto N, Kitab B, Haraguchi T, Matsuyama R, Nkogue CN, Hatai H, Miyoshi N, Murakami S, Tanaka Y, Takano JI, Shiogama Y, Yasutomi Y, Kohara M, Tsukiyama-Kohara K.

Virus Res. 2017 Jun 2;237:47-57. doi: 10.1016/j.virusres.2017.05.013. Epub 2017 May 25.

23.

Susceptibility and initial immune response of Tupaia belangeri cells to dengue virus infection.

Kayesh MEH, Kitab B, Sanada T, Hayasaka D, Morita K, Kohara M, Tsukiyama-Kohara K.

Infect Genet Evol. 2017 Jul;51:203-210. doi: 10.1016/j.meegid.2017.04.003. Epub 2017 Apr 6.

24.

Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model.

Tokunaga Y, Osawa Y, Ohtsuki T, Hayashi Y, Yamaji K, Yamane D, Hara M, Munekata K, Tsukiyama-Kohara K, Hishima T, Kojima S, Kimura K, Kohara M.

Sci Rep. 2017 Mar 23;7(1):325. doi: 10.1038/s41598-017-00282-w.

25.

Transmission of HBV DNA Mediated by Ceramide-Triggered Extracellular Vesicles.

Sanada T, Hirata Y, Naito Y, Yamamoto N, Kikkawa Y, Ishida Y, Yamasaki C, Tateno C, Ochiya T, Kohara M.

Cell Mol Gastroenterol Hepatol. 2016 Oct 24;3(2):272-283. doi: 10.1016/j.jcmgh.2016.10.003. eCollection 2017 Mar.

26.

An unusual case of Epstein-Barr virus-positive large B-cell lymphoma lacking various B-cell markers.

Nakatsuka SI, Yutani C, Kurashige M, Kohara M, Nagano T, Goto T, Takatsuka H, Ifuku H, Morii E.

Diagn Pathol. 2017 Jan 31;12(1):15. doi: 10.1186/s13000-017-0606-7.

27.

Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD-L in a yeast model system.

Takahashi S, Sato N, Kikuchi J, Kakinuma H, Okawa J, Masuyama Y, Iwasa S, Irokawa H, Hwang GW, Naganuma A, Kohara M, Kuge S.

Genes Cells. 2017 Feb;22(2):160-173. doi: 10.1111/gtc.12464. Epub 2017 Jan 18.

28.

Sensitization with vaccinia virus encoding H5N1 hemagglutinin restores immune potential against H5N1 influenza virus.

Yasui F, Itoh Y, Ikejiri A, Kitabatake M, Sakaguchi N, Munekata K, Shichinohe S, Hayashi Y, Ishigaki H, Nakayama M, Sakoda Y, Kida H, Ogasawara K, Kohara M.

Sci Rep. 2016 Nov 28;6:37915. doi: 10.1038/srep37915.

29.

Corrigendum to 'Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus' [Virology (2014) 157-168].

Yasui F, Kohara M, Kitabatake M, Nishiwaki T, Fujii H, Tateno C, Yoneda M, Morita K, Matsushima K, Koyasu S, Kai C.

Virology. 2016 Dec;499:397-398. doi: 10.1016/j.virol.2016.10.018. No abstract available.

30.

Immunohistochemical analysis of the novel marginal zone B-cell marker IRTA1 in malignant lymphoma.

Ikeda JI, Kohara M, Tsuruta Y, Nojima S, Tahara S, Ohshima K, Kurashige M, Wada N, Morii E.

Hum Pathol. 2017 Jan;59:70-79. doi: 10.1016/j.humpath.2016.09.011. Epub 2016 Sep 22.

PMID:
27666766
31.

Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection.

Kouwaki T, Fukushima Y, Daito T, Sanada T, Yamamoto N, Mifsud EJ, Leong CR, Tsukiyama-Kohara K, Kohara M, Matsumoto M, Seya T, Oshiumi H.

Front Immunol. 2016 Aug 31;7:335. doi: 10.3389/fimmu.2016.00335. eCollection 2016.

32.

Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus.

Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Tajima S, Takasaki T, Konishi E, Kato T, Kohara M, Takeyama H, Wakita T, Suzuki R.

Sci Rep. 2016 Jun 27;6:28688. doi: 10.1038/srep28688.

33.

Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibody.

Sugata K, Yasunaga J, Miura M, Akari H, Utsunomiya A, Nosaka K, Watanabe Y, Suzushima H, Koh KR, Nakagawa M, Kohara M, Matsuoka M.

Sci Rep. 2016 Jun 2;6:27150. doi: 10.1038/srep27150.

34.

Development of Acute Pericarditis Associated with New-onset Rheumatoid Arthritis in a Diabetic Patient with Renal Impairment: The Elusive Nature of Uremia.

Kohara M, Takeda S, Miki T, Ohara K, Yamanaka Y, Kawamata M, Hishida E, Wakabayashi N, Yamazaki T, Ichida M, Akimoto T, Muto S, Nagata D.

Intern Med. 2016;55(8):955-9. doi: 10.2169/internalmedicine.55.5438. Epub 2016 Apr 15.

35.

Establishment of an intermittent cold stress model using Tupaia belangeri and evaluation of compound C737 targeting neuron-restrictive silencer factor.

Hai-Ying C, Nagano K, Ezzikouri S, Yamaguchi C, Kayesh ME, Rebbani K, Kitab B, Nakano H, Kouji H, Kohara M, Tsukiyama-Kohara K.

Exp Anim. 2016 Jul 29;65(3):285-92. doi: 10.1538/expanim.15-0123. Epub 2016 Apr 4.

36.

Hepatitis C virus inhibitor synergism suggests multistep interactions between heat-shock protein 90 and hepatitis C virus replication.

Kubota N, Nomoto M, Hwang GW, Watanabe T, Kohara M, Wakita T, Naganuma A, Kuge S.

World J Hepatol. 2016 Feb 18;8(5):282-90. doi: 10.4254/wjh.v8.i5.282.

37.

Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice.

Osawa Y, Oboki K, Imamura J, Kojika E, Hayashi Y, Hishima T, Saibara T, Shibasaki F, Kohara M, Kimura K.

EBioMedicine. 2015 Oct 8;2(11):1751-8. doi: 10.1016/j.ebiom.2015.10.010. eCollection 2015 Nov.

38.

[Persistent infection factor of HBV].

Munakata T, Yamamoto N, Kohara M.

Nihon Rinsho. 2015 Dec;73 Suppl 9:357-60. Japanese. No abstract available.

PMID:
26845958
39.

Property of hepatitis B virus replication in Tupaia belangeri hepatocytes.

Sanada T, Tsukiyama-Kohara K, Yamamoto N, Ezzikouri S, Benjelloun S, Murakami S, Tanaka Y, Tateno C, Kohara M.

Biochem Biophys Res Commun. 2016 Jan 8;469(2):229-35. doi: 10.1016/j.bbrc.2015.11.121. Epub 2015 Nov 30.

40.

Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice.

Tateno C, Kawase Y, Tobita Y, Hamamura S, Ohshita H, Yokomichi H, Sanada H, Kakuni M, Shiota A, Kojima Y, Ishida Y, Shitara H, Wada NA, Tateishi H, Sudoh M, Nagatsuka S, Jishage K, Kohara M.

PLoS One. 2015 Nov 4;10(11):e0142145. doi: 10.1371/journal.pone.0142145. eCollection 2015.

41.

Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection.

Yamamoto N, Sato Y, Munakata T, Kakuni M, Tateno C, Sanada T, Hirata Y, Murakami S, Tanaka Y, Chayama K, Hatakeyama H, Hyodo M, Harashima H, Kohara M.

J Hepatol. 2016 Mar;64(3):547-55. doi: 10.1016/j.jhep.2015.10.014. Epub 2015 Oct 24.

42.
43.

M2 Macrophages Play Critical Roles in Progression of Inflammatory Liver Disease in Hepatitis C Virus Transgenic Mice.

Ohtsuki T, Kimura K, Tokunaga Y, Tsukiyama-Kohara K, Tateno C, Hayashi Y, Hishima T, Kohara M.

J Virol. 2015 Oct 14;90(1):300-7. doi: 10.1128/JVI.02293-15. Print 2016 Jan 1.

44.

Serum DHCR24 Auto-antibody as a new Biomarker for Progression of Hepatitis C.

Ezzikouri S, Kimura K, Sunagozaka H, Kaneko S, Inoue K, Nishimura T, Hishima T, Kohara M, Tsukiyama-Kohara K.

EBioMedicine. 2015 Apr 13;2(6):604-12. doi: 10.1016/j.ebiom.2015.04.007. eCollection 2015 Jun.

45.

Protective effect of cytotoxic T lymphocytes targeting HTLV-1 bZIP factor.

Sugata K, Yasunaga J, Mitobe Y, Miura M, Miyazato P, Kohara M, Matsuoka M.

Blood. 2015 Aug 27;126(9):1095-105. doi: 10.1182/blood-2015-04-641118. Epub 2015 Jun 10.

46.

3β-hydroxysterol δ24-reductase on the surface of hepatitis C virus-related hepatocellular carcinoma cells can be a target for molecular targeting therapy.

Saito M, Takano T, Nishimura T, Kohara M, Tsukiyama-Kohara K.

PLoS One. 2015 Apr 13;10(4):e0124197. doi: 10.1371/journal.pone.0124197. eCollection 2015.

47.

Survey of genome sequences in a wild sweet potato, Ipomoea trifida (H. B. K.) G. Don.

Hirakawa H, Okada Y, Tabuchi H, Shirasawa K, Watanabe A, Tsuruoka H, Minami C, Nakayama S, Sasamoto S, Kohara M, Kishida Y, Fujishiro T, Kato M, Nanri K, Komaki A, Yoshinaga M, Takahata Y, Tanaka M, Tabata S, Isobe SN.

DNA Res. 2015 Apr;22(2):171-9. doi: 10.1093/dnares/dsv002. Epub 2015 Mar 24.

48.

Hepatitis C virus attenuates mitochondrial lipid β-oxidation by downregulating mitochondrial trifunctional-protein expression.

Amako Y, Munakata T, Kohara M, Siddiqui A, Peers C, Harris M.

J Virol. 2015 Apr;89(8):4092-101. doi: 10.1128/JVI.01653-14. Epub 2015 Feb 11.

49.

The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus.

Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice CM, Harashima H, Kohara M, Tanaka Y, Takaoka A.

Immunity. 2015 Jan 20;42(1):123-32. doi: 10.1016/j.immuni.2014.12.016. Epub 2014 Dec 18.

50.

Animal model for hepatitis C virus infection.

Tsukiyama-Kohara K, Kohara M.

Uirusu. 2015;65(2):255-262. Review. Japanese.

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