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Items: 1 to 50 of 177

1.

Prolonged Duration Local Anesthesia by Combined Delivery of Capsaicin- and Tetrodotoxin-Loaded Liposomes.

Shomorony A, Santamaria CM, Zhao C, Rwei AY, Mehta M, Zurakowski D, Kohane DS.

Anesth Analg. 2019 Sep;129(3):709-717. doi: 10.1213/ANE.0000000000004108.

PMID:
31425210
2.

A Simple, Yet Multifunctional, Nanoformulation for Eradicating Tumors and Preventing Recurrence with Safely Low Administration Dose.

Liu Y, Xu Y, Zhang Z, Huo Y, Chen D, Ma W, Sun K, Tonga GY, Zhou G, Kohane DS, Tao K.

Nano Lett. 2019 Aug 14;19(8):5515-5523. doi: 10.1021/acs.nanolett.9b02053. Epub 2019 Aug 2.

PMID:
31362507
3.

Topical sustained drug delivery to the retina with a drug-eluting contact lens.

Ross AE, Bengani LC, Tulsan R, Maidana DE, Salvador-Culla B, Kobashi H, Kolovou PE, Zhai H, Taghizadeh K, Kuang L, Mehta M, Vavvas DG, Kohane DS, Ciolino JB.

Biomaterials. 2019 Oct;217:119285. doi: 10.1016/j.biomaterials.2019.119285. Epub 2019 Jun 21.

PMID:
31299627
4.

Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity.

Zhao C, Liu A, Santamaria CM, Shomorony A, Ji T, Wei T, Gordon A, Elofsson H, Mehta M, Yang R, Kohane DS.

Nat Commun. 2019 Jun 12;10(1):2566. doi: 10.1038/s41467-019-10296-9.

5.

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.

Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10674-10680. doi: 10.1073/pnas.1819889116. Epub 2019 Apr 30.

PMID:
31040208
6.

Transtympanic Delivery of Local Anesthetics for Pain in Acute Otitis Media.

Yang R, Saarinen R, Okonkwo OS, Hao Y, Mehta M, Kohane DS.

Mol Pharm. 2019 Apr 1;16(4):1555-1562. doi: 10.1021/acs.molpharmaceut.8b01235. Epub 2019 Mar 6.

7.

Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles.

Wang Y, Liu CH, Ji T, Mehta M, Wang W, Marino E, Chen J, Kohane DS.

Nat Commun. 2019 Feb 18;10(1):804. doi: 10.1038/s41467-019-08690-4.

8.

Quantile Regression and Its Applications: A Primer for Anesthesiologists.

Staffa SJ, Kohane DS, Zurakowski D.

Anesth Analg. 2019 Apr;128(4):820-830. doi: 10.1213/ANE.0000000000004017.

PMID:
30649075
9.

Nanoscale Bupivacaine Formulations To Enhance the Duration and Safety of Intravenous Regional Anesthesia.

Weldon C, Ji T, Nguyen MT, Rwei A, Wang W, Hao Y, Zhao C, Mehta M, Wang BY, Tsui J, Marini RP, Kohane DS.

ACS Nano. 2019 Jan 22;13(1):18-25. doi: 10.1021/acsnano.8b05408. Epub 2018 Nov 19.

PMID:
30351910
10.

PLGA-encapsulation of the Pseudomonas aeruginosa PopB vaccine antigen improves Th17 responses and confers protection against experimental acute pneumonia.

Schaefers MM, Duan B, Mizrahi B, Lu R, Reznor G, Kohane DS, Priebe GP.

Vaccine. 2018 Nov 12;36(46):6926-6932. doi: 10.1016/j.vaccine.2018.10.010. Epub 2018 Oct 9.

PMID:
30314911
11.

Treatment of Streptococcus pneumoniae otitis media in a chinchilla model by transtympanic delivery of antibiotics.

Yang R, Sabharwal V, Shlykova N, Okonkwo OS, Pelton SI, Kohane DS.

JCI Insight. 2018 Oct 4;3(19). pii: 123415. doi: 10.1172/jci.insight.123415.

12.

Externally triggered patient-controlled local anesthesia.

Cullion K, Kohane DS.

Pain Manag. 2018 Sep 1;8(5):313-315. doi: 10.2217/pmt-2018-0025. Epub 2018 Oct 3. No abstract available.

PMID:
30280652
13.

Long-acting liposomal corneal anesthetics.

Zhan C, Santamaria CM, Wang W, McAlvin JB, Kohane DS.

Biomaterials. 2018 Oct;181:372-377. doi: 10.1016/j.biomaterials.2018.07.054. Epub 2018 Aug 9.

PMID:
30099260
14.

Predicting the tissue depth for remote triggering of drug delivery systems.

Rwei AY, Wang B, Ji T, Kohane DS.

J Control Release. 2018 Sep 28;286:55-63. doi: 10.1016/j.jconrel.2018.07.033. Epub 2018 Jul 18.

PMID:
30030183
15.

Antibody-modified conduits for highly selective cytokine elimination from blood.

McAlvin JB, Wylie RG, Ramchander K, Nguyen MT, Lok CK, Moroi M, Shomorony A, Vasilyev NV, Armstrong P, Yang J, Lieber AM, Okonkwo OS, Karnik R, Kohane DS.

JCI Insight. 2018 Jul 12;3(13). pii: 121133. doi: 10.1172/jci.insight.121133.

16.

Synergy between chemical permeation enhancers and drug permeation across the tympanic membrane.

Yang R, Okonkwo OS, Zurakowski D, Kohane DS.

J Control Release. 2018 Nov 10;289:94-101. doi: 10.1016/j.jconrel.2018.06.019. Epub 2018 Jun 19.

17.

BaTiO3-core Au-shell nanoparticles for photothermal therapy and bimodal imaging.

Wang Y, Barhoumi A, Tong R, Wang W, Ji T, Deng X, Li L, Lyon SA, Reznor G, Zurakowski D, Kohane DS.

Acta Biomater. 2018 May;72:287-294. doi: 10.1016/j.actbio.2018.03.029. Epub 2018 Mar 22.

18.

High-frequency, low-intensity ultrasound and microbubbles enhance nerve blockade.

Cullion K, Santamaria CM, Zhan C, Zurakowski D, Sun T, Pemberton GL, McDannold NJ, Kohane DS.

J Control Release. 2018 Apr 28;276:150-156. doi: 10.1016/j.jconrel.2018.02.027. Epub 2018 Feb 20. No abstract available.

19.

Prolonged Duration Local Anesthesia Using Liposomal Bupivacaine Combined With Liposomal Dexamethasone and Dexmedetomidine.

Rwei AY, Sherburne RT, Zurakowski D, Wang B, Kohane DS.

Anesth Analg. 2018 Apr;126(4):1170-1175. doi: 10.1213/ANE.0000000000002719.

20.

Hollow Silica Nanoparticles Penetrate the Peripheral Nerve and Enhance the Nerve Blockade from Tetrodotoxin.

Liu Q, Santamaria CM, Wei T, Zhao C, Ji T, Yang T, Shomorony A, Wang BY, Kohane DS.

Nano Lett. 2018 Jan 10;18(1):32-37. doi: 10.1021/acs.nanolett.7b02461. Epub 2017 Dec 11.

PMID:
29227106
21.

Ultrasound-triggered liposomes for on-demand local anesthesia.

Cullion K, Rwei AY, Kohane DS.

Ther Deliv. 2018 Jan;9(1):5-8. doi: 10.4155/tde-2017-0100. No abstract available.

PMID:
29216807
22.

Ultrasound-triggered local anaesthesia.

Rwei AY, Paris JL, Wang B, Wang W, Axon CD, Vallet-RegĂ­ M, Langer R, Kohane DS.

Nat Biomed Eng. 2017;1:644-653. doi: 10.1038/s41551-017-0117-6. Epub 2017 Aug 9.

23.

Light-Emitting Photon-Upconversion Nanoparticles in the Generation of Transdermal Reactive-Oxygen Species.

Prieto M, Rwei AY, Alejo T, Wei T, Lopez-Franco MT, Mendoza G, Sebastian V, Kohane DS, Arruebo M.

ACS Appl Mater Interfaces. 2017 Dec 6;9(48):41737-41747. doi: 10.1021/acsami.7b14812. Epub 2017 Nov 21.

PMID:
29131564
24.

Enhanced Triggering of Local Anesthetic Particles by Photosensitization and Photothermal Effect Using a Common Wavelength.

Rwei AY, Wang BY, Ji T, Zhan C, Kohane DS.

Nano Lett. 2017 Nov 8;17(11):7138-7145. doi: 10.1021/acs.nanolett.7b04176. Epub 2017 Oct 23.

PMID:
29058443
25.

Drug delivery systems for prolonged duration local anesthesia.

Santamaria CM, Woodruff A, Yang R, Kohane DS.

Mater Today (Kidlington). 2017 Jan-Feb;20(1):22-31. doi: 10.1016/j.mattod.2016.11.019. Epub 2016 Dec 20.

26.

Getting Drugs Across Biological Barriers.

Yang R, Wei T, Goldberg H, Wang W, Cullion K, Kohane DS.

Adv Mater. 2017 Oct;29(37). doi: 10.1002/adma.201606596. Epub 2017 Jul 28. Review.

27.

Combination Clearance Therapy and Barbiturate Coma for Severe Carbamazepine Overdose.

Agulnik A, Kelly DP, Bruccoleri R, Yuskaitis C, Ebrahimi-Fakhari D, Sahin M, Burns MM, Kohane DS.

Pediatrics. 2017 May;139(5). pii: e20161560. doi: 10.1542/peds.2016-1560.

28.

Tetrodotoxin, Epinephrine, and Chemical Permeation Enhancer Combinations in Peripheral Nerve Blockade.

Santamaria CM, Zhan C, McAlvin JB, Zurakowski D, Kohane DS.

Anesth Analg. 2017 Jun;124(6):1804-1812. doi: 10.1213/ANE.0000000000002072.

29.

Strong tissue glue with tunable elasticity.

Kelmansky R, McAlvin BJ, Nyska A, Dohlman JC, Chiang HH, Hashimoto M, Kohane DS, Mizrahi B.

Acta Biomater. 2017 Apr 15;53:93-99. doi: 10.1016/j.actbio.2017.02.009. Epub 2017 Feb 9.

PMID:
28189813
30.

Multiply repeatable and adjustable on-demand phototriggered local anesthesia.

Rwei AY, Zhan C, Wang B, Kohane DS.

J Control Release. 2017 Apr 10;251:68-74. doi: 10.1016/j.jconrel.2017.01.031. Epub 2017 Jan 31.

31.

Ultrasensitive Phototriggered Local Anesthesia.

Zhan C, Wang W, Santamaria C, Wang B, Rwei A, Timko BP, Kohane DS.

Nano Lett. 2017 Feb 8;17(2):660-665. doi: 10.1021/acs.nanolett.6b03588. Epub 2017 Jan 6.

32.

Drug delivery, biomaterials and nanomedicine: an interview with Daniel S Kohane.

Kohane DS.

Future Sci OA. 2016 Aug 19;2(3):FSO138. doi: 10.4155/fsoa-2016-0050. eCollection 2016 Sep.

33.

Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles.

Zaman P, Wang J, Blau A, Wang W, Li T, Kohane DS, Loscalzo J, Zhang YY.

Int J Nanomedicine. 2016 Nov 18;11:6149-6159. eCollection 2016.

34.

Core-Shell Nanostars for Multimodal Therapy and Imaging.

Li M, Li L, Zhan C, Kohane DS.

Theranostics. 2016 Oct 1;6(13):2306-2313. eCollection 2016.

35.

Phototriggered Drug Delivery Using Inorganic Nanomaterials.

Liu Q, Zhan C, Kohane DS.

Bioconjug Chem. 2017 Jan 18;28(1):98-104. doi: 10.1021/acs.bioconjchem.6b00448. Epub 2016 Oct 7. Review.

36.

Treatment of otitis media by transtympanic delivery of antibiotics.

Yang R, Sabharwal V, Okonkwo OS, Shlykova N, Tong R, Lin LY, Wang W, Guo S, Rosowski JJ, Pelton SI, Kohane DS.

Sci Transl Med. 2016 Sep 14;8(356):356ra120. doi: 10.1126/scitranslmed.aaf4363.

37.

Latanoprost-Eluting Contact Lenses in Glaucomatous Monkeys.

Ciolino JB, Ross AE, Tulsan R, Watts AC, Wang RF, Zurakowski D, Serle JB, Kohane DS.

Ophthalmology. 2016 Oct;123(10):2085-92. doi: 10.1016/j.ophtha.2016.06.038. Epub 2016 Aug 29.

PMID:
27586444
38.

Enhanced Precision of Nanoparticle Phototargeting in Vivo at a Safe Irradiance.

Liu Q, Wang W, Zhan C, Yang T, Kohane DS.

Nano Lett. 2016 Jul 13;16(7):4516-20. doi: 10.1021/acs.nanolett.6b01730. Epub 2016 Jun 21.

PMID:
27310596
39.

RNA therapeutics - The potential treatment for myocardial infarction.

Chu H, Kohane DS, Langer R.

Regen Ther. 2016 Jun 1;4:83-91. doi: 10.1016/j.reth.2016.03.002. eCollection 2016 Jun. Review.

40.

A Supramolecular Shear-Thinning Anti-Inflammatory Steroid Hydrogel.

Liu Q, Zhan C, Barhoumi A, Wang W, Santamaria C, McAlvin JB, Kohane DS.

Adv Mater. 2016 Aug;28(31):6680-6. doi: 10.1002/adma.201601147. Epub 2016 May 23.

PMID:
27214390
41.

Titanium Coating of the Boston Keratoprosthesis.

Salvador-Culla B, Jeong KJ, Kolovou PE, Chiang HH, Chodosh J, Dohlman CH, Kohane DS.

Transl Vis Sci Technol. 2016 Apr 28;5(2):17. eCollection 2016 Apr.

42.

Extended Release of Native Drug Conjugated in Polyketal Microparticles.

Guo S, Nakagawa Y, Barhoumi A, Wang W, Zhan C, Tong R, Santamaria C, Kohane DS.

J Am Chem Soc. 2016 May 18;138(19):6127-30. doi: 10.1021/jacs.6b02435. Epub 2016 May 5.

PMID:
27148927
43.

Self-assembled gemcitabine-gadolinium nanoparticles for magnetic resonance imaging and cancer therapy.

Li L, Tong R, Li M, Kohane DS.

Acta Biomater. 2016 Mar;33:34-9. doi: 10.1016/j.actbio.2016.01.039. Epub 2016 Jan 27.

44.

Phototriggered Local Anesthesia.

Zhan C, Wang W, McAlvin JB, Guo S, Timko BP, Santamaria C, Kohane DS.

Nano Lett. 2016 Jan 13;16(1):177-81. doi: 10.1021/acs.nanolett.5b03440. Epub 2015 Dec 14.

PMID:
26654461
45.

Photoresponsive nanoparticles for drug delivery.

Rwei AY, Wang W, Kohane DS.

Nano Today. 2015 Aug 1;10(4):451-467. Epub 2015 Jul 15.

46.

Repeatable and adjustable on-demand sciatic nerve block with phototriggerable liposomes.

Rwei AY, Lee JJ, Zhan C, Liu Q, Ok MT, Shankarappa SA, Langer R, Kohane DS.

Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15719-24. doi: 10.1073/pnas.1518791112. Epub 2015 Dec 7.

47.

Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF(165).

Lim DK, Wylie RG, Langer R, Kohane DS.

Biomaterials. 2016 Jan;77:130-138. doi: 10.1016/j.biomaterials.2015.10.074. Epub 2015 Oct 30.

48.

New Strategies in Cancer Nanomedicine.

Tong R, Kohane DS.

Annu Rev Pharmacol Toxicol. 2016;56:41-57. doi: 10.1146/annurev-pharmtox-010715-103456. Epub 2015 Oct 28. Review.

PMID:
26514197
49.

Ultraviolet light-mediated drug delivery: Principles, applications, and challenges.

Barhoumi A, Liu Q, Kohane DS.

J Control Release. 2015 Dec 10;219:31-42. doi: 10.1016/j.jconrel.2015.07.018. Epub 2015 Jul 21. Review.

PMID:
26208426
50.

Efficient Triplet-Triplet Annihilation-Based Upconversion for Nanoparticle Phototargeting.

Wang W, Liu Q, Zhan C, Barhoumi A, Yang T, Wylie RG, Armstrong PA, Kohane DS.

Nano Lett. 2015 Oct 14;15(10):6332-8. doi: 10.1021/acs.nanolett.5b01325. Epub 2015 Jul 9.

PMID:
26158690

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