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Items: 29


Irisin induces trophoblast differentiation via AMPK activation in the human placenta.

Drewlo S, Johnson E, Kilburn BA, Kadam L, Armistead B, Kohan-Ghadr HR.

J Cell Physiol. 2020 Feb 5. doi: 10.1002/jcp.29613. [Epub ahead of print]


Hypochlorous acid reversibly inhibits caspase-3: a potential regulator of apoptosis.

Jeelani R, Chatzicharalampous C, Kohan-Ghadr HR, Bai D, Morris RT, Sliskovic I, Awonuga A, Abu-Soud HM.

Free Radic Res. 2020 Jan;54(1):43-56. doi: 10.1080/10715762.2019.1694675. Epub 2020 Jan 7.


The inhibition of lactoperoxidase catalytic activity through mesna (2-mercaptoethane sodium sulfonate).

Jahanbakhsh S, Dekhne MS, Kohan-Ghadr HR, Bai D, Awonuga A, Morris RT, Yang Z, Abu-Soud HM.

J Inorg Biochem. 2020 Feb;203:110911. doi: 10.1016/j.jinorgbio.2019.110911. Epub 2019 Nov 12.


Endocervical trophoblast for interrogating the fetal genome and assessing pregnancy health at five weeks.

Kadam L, Jain C, Kohan-Ghadr HR, Krawetz SA, Drewlo S, Armant DR.

Eur J Med Genet. 2019 Aug;62(8):103690. doi: 10.1016/j.ejmg.2019.103690. Epub 2019 Jun 18.


Rosiglitazone blocks first trimester in-vitro placental injury caused by NF-κB-mediated inflammation.

Kadam L, Kilburn B, Baczyk D, Kohan-Ghadr HR, Kingdom J, Drewlo S.

Sci Rep. 2019 Feb 14;9(1):2018. doi: 10.1038/s41598-018-38336-2.


Rosiglitazone augments antioxidant response in the human trophoblast and prevents apoptosis†.

Kohan-Ghadr HR, Kilburn BA, Kadam L, Johnson E, Kolb BL, Rodriguez-Kovacs J, Hertz M, Armant DR, Drewlo S.

Biol Reprod. 2019 Feb 1;100(2):479-494. doi: 10.1093/biolre/ioy186.


Acrolein, a commonly found environmental toxin, causes oocyte mitochondrial dysfunction and negatively affects embryo development.

Jeelani R, Chatzicharalampous C, Kohan-Ghadr HR, Awonuga A, Joshi N, Morris RT, Abu-Soud HM.

Free Radic Res. 2018 Sep;52(9):929-938. doi: 10.1080/10715762.2018.1487559. Epub 2018 Oct 12.


Nifedipine Prevents Apoptosis of Alcohol-Exposed First-Trimester Trophoblast Cells.

Bolnick AD, Bolnick JM, Kohan-Ghadr HR, Kilburn BA, Hertz M, Dai J, Drewlo S, Armant DR.

Alcohol Clin Exp Res. 2018 Jan;42(1):53-60. doi: 10.1111/acer.13534. Epub 2017 Nov 22.


Dimercapto-1-propanesulfonic acid (DMPS) induces metaphase II mouse oocyte deterioration.

Aldhaheri SR, Jeelani R, Kohan-Ghadr HR, Khan SN, Mikhael S, Washington C, Morris RT, Abu-Soud HM.

Free Radic Biol Med. 2017 Nov;112:445-451. doi: 10.1016/j.freeradbiomed.2017.08.015. Epub 2017 Aug 24.


Mesna (2-mercaptoethane sodium sulfonate) functions as a regulator of myeloperoxidase.

Jeelani R, Jahanbakhsh S, Kohan-Ghadr HR, Thakur M, Khan S, Aldhaheri SR, Yang Z, Andreana P, Morris R, Abu-Soud HM.

Free Radic Biol Med. 2017 Sep;110:54-62. doi: 10.1016/j.freeradbiomed.2017.05.019. Epub 2017 May 25.


Cyclophosphamide and acrolein induced oxidative stress leading to deterioration of metaphase II mouse oocyte quality.

Jeelani R, Khan SN, Shaeib F, Kohan-Ghadr HR, Aldhaheri SR, Najafi T, Thakur M, Morris R, Abu-Soud HM.

Free Radic Biol Med. 2017 Sep;110:11-18. doi: 10.1016/j.freeradbiomed.2017.05.006. Epub 2017 May 9.


Enhancement of trophoblast differentiation and survival by low molecular weight heparin requires heparin-binding EGF-like growth factor.

Bolnick AD, Bolnick JM, Kohan-Ghadr HR, Kilburn BA, Pasalodos OJ, Singhal PK, Dai J, Diamond MP, Armant DR, Drewlo S.

Hum Reprod. 2017 Jun 1;32(6):1218-1229. doi: 10.1093/humrep/dex069.


Galactose and its Metabolites Deteriorate Metaphase II Mouse Oocyte Quality and Subsequent Embryo Development by Disrupting the Spindle Structure.

Thakur M, Shaeib F, Khan SN, Kohan-Ghadr HR, Jeelani R, Aldhaheri SR, Gonik B, Abu-Soud HM.

Sci Rep. 2017 Mar 22;7(1):231. doi: 10.1038/s41598-017-00159-y.


Rosiglitazone Regulates TLR4 and Rescues HO-1 and NRF2 Expression in Myometrial and Decidual Macrophages in Inflammation-Induced Preterm Birth.

Kadam L, Gomez-Lopez N, Mial TN, Kohan-Ghadr HR, Drewlo S.

Reprod Sci. 2017 Dec;24(12):1590-1599. doi: 10.1177/1933719117697128. Epub 2017 Mar 21.


Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells.

Moussette S, Al Tuwaijri A, Kohan-Ghadr HR, Elzein S, Farias R, Bérubé J, Ho B, Laprise C, Goodyer CG, Rousseau S, Naumova AK.

PLoS One. 2017 Feb 27;12(2):e0172707. doi: 10.1371/journal.pone.0172707. eCollection 2017.


Fetal genome profiling at 5 weeks of gestation after noninvasive isolation of trophoblast cells from the endocervical canal.

Jain CV, Kadam L, van Dijk M, Kohan-Ghadr HR, Kilburn BA, Hartman C, Mazzorana V, Visser A, Hertz M, Bolnick AD, Fritz R, Armant DR, Drewlo S.

Sci Transl Med. 2016 Nov 2;8(363):363re4.


Altered Biomarkers in Trophoblast Cells Obtained Noninvasively Prior to Clinical Manifestation of Perinatal Disease.

Bolnick JM, Kohan-Ghadr HR, Fritz R, Bolnick AD, Kilburn BA, Diamond MP, Armant DR, Drewlo S.

Sci Rep. 2016 Sep 23;6:32382. doi: 10.1038/srep32382.


Reduced homeobox protein MSX1 in human endometrial tissue is linked to infertility.

Bolnick AD, Bolnick JM, Kilburn BA, Stewart T, Oakes J, Rodriguez-Kovacs J, Kohan-Ghadr HR, Dai J, Diamond MP, Hirota Y, Drewlo S, Dey SK, Armant DR; NICHD National Cooperative Reproductive Medicine Network.

Hum Reprod. 2016 Sep;31(9):2042-50. doi: 10.1093/humrep/dew143. Epub 2016 Jun 16.


Dynamics of extended-spectrum cephalosporin resistance in pathogenic Escherichia coli isolated from diseased pigs in Quebec, Canada.

Jahanbakhsh S, Smith MG, Kohan-Ghadr HR, Letellier A, Abraham S, Trott DJ, Fairbrother JM.

Int J Antimicrob Agents. 2016 Aug;48(2):194-202. doi: 10.1016/j.ijantimicag.2016.05.001. Epub 2016 Jun 1.


The Impact of Myeloperoxidase and Activated Macrophages on Metaphase II Mouse Oocyte Quality.

Shaeib F, Khan SN, Thakur M, Kohan-Ghadr HR, Drewlo S, Saed GM, Pennathur S, Abu-Soud HM.

PLoS One. 2016 Mar 16;11(3):e0151160. doi: 10.1371/journal.pone.0151160. eCollection 2016.


Potential role of epigenetic mechanisms in regulation of trophoblast differentiation, migration, and invasion in the human placenta.

Kohan-Ghadr HR, Kadam L, Jain C, Armant DR, Drewlo S.

Cell Adh Migr. 2016 Mar 3;10(1-2):126-35. doi: 10.1080/19336918.2015.1098800. Epub 2016 Jan 8. Review.


Trophoblast retrieval and isolation from the cervix (TRIC) is unaffected by early gestational age or maternal obesity.

Fritz R, Kohan-Ghadr HR, Sacher A, Bolnick AD, Kilburn BA, Bolnick JM, Diamond MP, Drewlo S, Armant DR.

Prenat Diagn. 2015 Dec;35(12):1218-22. doi: 10.1002/pd.4681. Epub 2015 Sep 20.


Noninvasive detection of trophoblast protein signatures linked to early pregnancy loss using trophoblast retrieval and isolation from the cervix (TRIC).

Fritz R, Kohan-Ghadr HR, Bolnick JM, Bolnick AD, Kilburn BA, Diamond MP, Drewlo S, Armant DR.

Fertil Steril. 2015 Aug;104(2):339-46.e4. doi: 10.1016/j.fertnstert.2015.05.010. Epub 2015 Jun 11.


The balancing act - PPAR-γ's roles at the maternal-fetal interface.

Kadam L, Kohan-Ghadr HR, Drewlo S.

Syst Biol Reprod Med. 2015 Apr;61(2):65-71. doi: 10.3109/19396368.2014.991881. Epub 2014 Dec 5. Review.


Sex- and age-dependent DNA methylation at the 17q12-q21 locus associated with childhood asthma.

Naumova AK, Al Tuwaijri A, Morin A, Vaillancourt VT, Madore AM, Berlivet S, Kohan-Ghadr HR, Moussette S, Laprise C.

Hum Genet. 2013 Jul;132(7):811-22. doi: 10.1007/s00439-013-1298-z. Epub 2013 Apr 2. Erratum in: Hum Genet. 2013 Jul;132(7):823. Vaillancout, Vanessa T [corrected to Vaillancourt, Vanessa T].


Developmental and epigenetic anomalies in cloned cattle.

Smith LC, Suzuki J Jr, Goff AK, Filion F, Therrien J, Murphy BD, Kohan-Ghadr HR, Lefebvre R, Brisville AC, Buczinski S, Fecteau G, Perecin F, Meirelles FV.

Reprod Domest Anim. 2012 Aug;47 Suppl 4:107-14. doi: 10.1111/j.1439-0531.2012.02063.x. Review.


Aberrant expression of E-cadherin and β-catenin proteins in placenta of bovine embryos derived from somatic cell nuclear transfer.

Kohan-Ghadr HR, Smith LC, Arnold DR, Murphy BD, Lefebvre RC.

Reprod Fertil Dev. 2012;24(4):588-98. doi: 10.1071/RD11162.


Endocrine profiles of somatic nuclear transfer-derived pregnancies in dairy cattle.

Kohan-Ghadr HR, Fecteau G, Smith LC, Murphy BD, Lefebvre RC.

Theriogenology. 2011 Sep 15;76(5):911-20. doi: 10.1016/j.theriogenology.2011.04.022. Epub 2011 Jun 25.


Ultrasonographic and histological characterization of the placenta of somatic nuclear transfer-derived pregnancies in dairy cattle.

Kohan-Ghadr HR, Lefebvre RC, Fecteau G, Smith LC, Murphy BD, Suzuki Junior J, Girard C, Hélie P.

Theriogenology. 2008 Jan 15;69(2):218-30. Epub 2007 Nov 5.


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