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Antecedent Carbapenem Exposure as a Risk Factor for Non-Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae (NCPCRE) and Carbapenemase-Producing Enterobacteriaceae (CPE).

Marimuthu K, Ng OT, Cherng BPZ, Fong RKC, Pada SK, De PP, Ooi ST, Smitasin N, Thoon KC, Krishnan PU, Ang M, Chan DSG, Kwa ALH, Deepak RN, Chan YK, Chan YFZ, Huan X, Linn KZ, Tee NWS, Tan TY, Koh TH, Lin RTP, Hsu LY, Sengupta S, Paterson DL, Perencevich E, Harbarth S, Teo J, Venkatachalam I; CaPES study group.

Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.00845-19. doi: 10.1128/AAC.00845-19. [Epub ahead of print]


Diabetes induces myeloid bias in bone marrow progenitors associated with enhanced wound macrophage accumulation and impaired healing.

Barman PK, Urao N, Koh TJ.

J Pathol. 2019 Jul 25. doi: 10.1002/path.5330. [Epub ahead of print]


Perturbation-Induced Seeding and Crystallization of Hybrid Perovskites over Surface-Modified Substrates for Optoelectronic Devices.

Ahmad R, Surendran A, Harikesh PC, Haselsberger R, Jamaludin NF, John RA, Koh TM, Bruno A, Leong WL, Mathews N, Michel-Beyerle ME, Mhaisalkar SG.

ACS Appl Mater Interfaces. 2019 Aug 7;11(31):27727-27734. doi: 10.1021/acsami.9b05965. Epub 2019 Jul 26.


Independent Predictors of Cardiac Mortality and Hospitalization for Heart Failure in a Multi-Ethnic Asian ST-segment Elevation Myocardial Infarction Population Treated by Primary Percutaneous Coronary Intervention.

Bulluck H, Zheng H, Chan MY, Foin N, Foo DC, Lee CW, Lim ST, Sahlen A, Tan HC, Tan JW, Tong KL, Wong AS, Wong PE, Yeo KK, Foo LL, Chua TS, Koh TH, Hausenloy DJ.

Sci Rep. 2019 Jul 11;9(1):10072. doi: 10.1038/s41598-019-46486-0.


Cesium Oleate Passivation for Stable Perovskite Photovoltaics.

Guo X, Koh TM, Febriansyah B, Han G, Bhaumik S, Li J, Jamaludin NF, Ghosh B, Chen X, Mhaisalkar S, Mathews N.

ACS Appl Mater Interfaces. 2019 Aug 7;11(31):27882-27889. doi: 10.1021/acsami.9b08026. Epub 2019 Jul 23.


Seroepidemiology and genotyping of hepatitis E virus in Singapore reveal rise in number of cases and similarity of human strains to those detected in pig livers.

Wong CC, Thean SM, Ng Y, Kang JSL, Ng TY, Chau ML, Koh TH, Chan KP.

Zoonoses Public Health. 2019 Jul 11. doi: 10.1111/zph.12624. [Epub ahead of print]


One hypervirulent clone, sequence type 283, accounts for a large proportion of invasive Streptococcus agalactiae isolated from humans and diseased tilapia in Southeast Asia.

Barkham T, Zadoks RN, Azmai MNA, Baker S, Bich VTN, Chalker V, Chau ML, Dance D, Deepak RN, van Doorn HR, Gutierrez RA, Holmes MA, Huong LNP, Koh TH, Martins E, Mehershahi K, Newton P, Ng LC, Phuoc NN, Sangwichian O, Sawatwong P, Surin U, Tan TY, Tang WY, Thuy NV, Turner P, Vongsouvath M, Zhang D, Whistler T, Chen SL.

PLoS Negl Trop Dis. 2019 Jun 27;13(6):e0007421. doi: 10.1371/journal.pntd.0007421. eCollection 2019 Jun.


A pilot study on the analytic sensitivity and accuracy of the Check-Points Check Direct CPE, Cepheid Xpert Carba-R, and ChromID CARBA SMART chromogenic agar for detecting carbapenemase-producing Enterobacteriaceae.

Vasoo S, Hon PY, Hsu JP, Koh TH, De PP.

J Glob Antimicrob Resist. 2019 Jun 13;18:235-237. doi: 10.1016/j.jgar.2019.06.003. [Epub ahead of print] No abstract available.


Nocturnal hemodialysis: improved quality of life and patient outcomes.

Koh TJK.

Int J Nephrol Renovasc Dis. 2019 Apr 3;12:59-68. doi: 10.2147/IJNRD.S165919. eCollection 2019. Review.


Performance Evaluation of Precast Concrete Using Microwave Heating Form.

Choi H, Koh T, Choi H, Hama Y.

Materials (Basel). 2019 Apr 3;12(7). pii: E1113. doi: 10.3390/ma12071113.


Skin Wounding-Induced Monocyte Expansion in Mice Is Not Abrogated by IL-1 Receptor 1 Deficiency.

Barman PK, Pang J, Urao N, Koh TJ.

J Immunol. 2019 May 1;202(9):2720-2727. doi: 10.4049/jimmunol.1801481. Epub 2019 Mar 25.


Carotid Arterial Calcium Scoring Using Upper Airway Computed Tomography in Patients with Obstructive Sleep Apnea: Efficacy as a Clinical Predictor of Cerebrocardiovascular Disease.

Lee JH, Kang EJ, Bae WY, Kim JK, Choi JH, Kim CH, Kim SJ, Jo KS, Kim MS, Koh TK.

Korean J Radiol. 2019 Apr;20(4):631-640. doi: 10.3348/kjr.2018.0550.


Inter-rater reliability between experienced and inexperienced otolaryngologists using Koo's drug-induced sleep endoscopy classification system.

Koo SK, Lee SH, Koh TK, Kim YJ, Moon JS, Lee HB, Park GH.

Eur Arch Otorhinolaryngol. 2019 May;276(5):1525-1531. doi: 10.1007/s00405-019-05386-9. Epub 2019 Mar 18.


Risk factors and outcomes associated with the isolation of polymyxin B and carbapenem-resistant Enterobacteriaceae spp.: A case-control study.

Teo JQ, Chang CW, Leck H, Tang CY, Lee SJ, Cai Y, Ong RT, Koh TH, Tan TT, Kwa AL.

Int J Antimicrob Agents. 2019 May;53(5):657-662. doi: 10.1016/j.ijantimicag.2019.03.011. Epub 2019 Mar 14.


First Case of Ceftriaxone-Resistant Multidrug-Resistant Neisseria gonorrhoeae in Singapore.

Ko KKK, Chio MTW, Goh SS, Tan AL, Koh TH, Abdul Rahman NB.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02624-18. doi: 10.1128/AAC.02624-18. Print 2019 May. No abstract available.


25OUse of CTTA to predict treatment response in patients with EGFR T790M+ NSCLC treated with osimertinib.

Tan WL, Tran Nguyen TA, Koh TS, Priyanthi Hennedige T, Yip CSP, Tan SH, Tan DSW, Thng CH, Lim DW, Ng QS.

Ann Oncol. 2019 Feb 1;30(Supplement_1). pii: mdz030. doi: 10.1093/annonc/mdz030. No abstract available.


Correction to 3D Printed Quantum Dot Light-Emitting Diodes.

Kong YL, Tamargo IA, Kim H, Johnson BN, Gupta MK, Koh TW, Chin HA, Steingart DA, Rand BP, McAlpine MC.

Nano Lett. 2019 Mar 13;19(3):2187. doi: 10.1021/acs.nanolett.9b00598. Epub 2019 Feb 18. No abstract available.


Safety, efficacy, and pharmacokinetics of bedaquiline in Japanese patients with pulmonary multidrug-resistant tuberculosis: An interim analysis of an open-label, phase 2 study.

Tsuyuguchi K, Sasaki Y, Mitarai S, Kurosawa K, Saito Y, Koh T.

Respir Investig. 2019 Jul;57(4):345-353. doi: 10.1016/j.resinv.2019.01.001. Epub 2019 Feb 7.


[A Case of a Patient with Multiple Liver Metastases of Colorectal Cancer with Relapse-Free, Long-Term Survival and Responding Completely to Chemotherapy after Primary Lesion Resection].

Nishio M, Sakai T, Mizutani T, Soga K, Koh T, Oguro A, Nakagawa N.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2279-2281. Japanese.


Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.

Lai GGY, Lim TH, Lim J, Liew PJR, Kwang XL, Nahar R, Aung ZW, Takano A, Lee YY, Lau DPX, Tan GS, Tan SH, Tan WL, Ang MK, Toh CK, Tan BS, Devanand A, Too CW, Gogna A, Ong BH, Koh TPT, Kanesvaran R, Ng QS, Jain A, Rajasekaran T, Yuan J, Lim TKH, Lim AST, Hillmer AM, Lim WT, Iyer NG, Tam WL, Zhai W, Tan EH, Tan DSW.

J Clin Oncol. 2019 Apr 10;37(11):876-884. doi: 10.1200/JCO.18.00177. Epub 2019 Jan 24.


Quantitative analysis of carotid arterial calcification using airway CT in obstructive sleep apnea.

Koh TK, Kang EJ, Bae WY, Kim SW, Kim CH, Koo SK, Kim SJ, Kim MS, Lee JH.

Auris Nasus Larynx. 2019 Aug;46(4):559-564. doi: 10.1016/j.anl.2018.11.015. Epub 2018 Dec 7.


Asian Liver Transplant Network Clinical Guidelines on Immunosuppression in Liver Transplantation.

Tan PS, Muthiah MD, Koh T, Teoh YL, Chan A, Kow A, Zheng Q, Kwon CHD, Lee GH, Lesmana CRA, de Villa V, Fung J, Lim K.

Transplantation. 2019 Mar;103(3):470-480. doi: 10.1097/TP.0000000000002532.


Integrated pharmacokinetic-pharmacodynamic modeling to evaluate empiric carbapenem therapy in bloodstream infections.

Lim TP, Wang R, Poh GQ, Koh TH, Tan TY, Lee W, Teo JQ, Cai Y, Tan TT, Ee PLR, Kwa AL.

Infect Drug Resist. 2018 Sep 27;11:1591-1596. doi: 10.2147/IDR.S168191. eCollection 2018.


Low threshold and efficient multiple exciton generation in halide perovskite nanocrystals.

Li M, Begum R, Fu J, Xu Q, Koh TM, Veldhuis SA, Grätzel M, Mathews N, Mhaisalkar S, Sum TC.

Nat Commun. 2018 Oct 10;9(1):4197. doi: 10.1038/s41467-018-06596-1.


Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury.

Corbiere TF, Weinheimer-Haus EM, Judex S, Koh TJ.

J Funct Morphol Kinesiol. 2018 Mar;3(1). pii: 1. doi: 10.3390/jfmk3010001. Epub 2017 Dec 21.


Oxidant Signaling Mediated by Nox2 in Neutrophils Promotes Regenerative Myelopoiesis and Tissue Recovery following Ischemic Damage.

Fang MM, Barman PK, Thiruppathi M, Mirza RE, McKinney RD, Deng J, Christman JW, Du X, Fukai T, Ennis WJ, Koh TJ, Ushio-Fukai M, Urao N.

J Immunol. 2018 Oct 15;201(8):2414-2426. doi: 10.4049/jimmunol.1800252. Epub 2018 Sep 10.


Optimal Treatment for High-Risk Prostate Cancer.

Ong WL, Koh TL, Millar J.

JAMA. 2018 Jul 24;320(4):404-405. doi: 10.1001/jama.2018.6709. No abstract available.


A simple B 1 correction method for dynamic contrast-enhanced MRI.

Li ZF, Zhao W, Qi TF, Gao C, Gu Q, Zhao JS, Koh TS.

Phys Med Biol. 2018 Aug 10;63(16):16NT01. doi: 10.1088/1361-6560/aad519.


Thyroid cancer among female workers in Korea, 2007-2015.

Kang S, Song J, Koh T, Park O, Park JT, Lee WJ.

Ann Occup Environ Med. 2018 Jul 16;30:48. doi: 10.1186/s40557-018-0259-3. eCollection 2018.


Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination.

Lam MMC, Wyres KL, Duchêne S, Wick RR, Judd LM, Gan YH, Hoh CH, Archuleta S, Molton JS, Kalimuddin S, Koh TH, Passet V, Brisse S, Holt KE.

Nat Commun. 2018 Jul 13;9(1):2703. doi: 10.1038/s41467-018-05114-7.


Increased skin blood flow during low intensity vibration in human participants: Analysis of control mechanisms using short-time Fourier transform.

Tzen YT, Weinheimer-Haus EM, Corbiere TF, Koh TJ.

PLoS One. 2018 Jul 12;13(7):e0200247. doi: 10.1371/journal.pone.0200247. eCollection 2018.


Rapid Antibiotic Combination Testing for Carbapenem-Resistant Gram-Negative Bacteria within Six Hours Using ATP Bioluminescence.

Cai Y, Seah CL, Leck H, Lim TP, Teo JQ, Lee W, Tan TT, Koh TH, Ee PLR, Kwa AL.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00183-18. doi: 10.1128/AAC.00183-18. Print 2018 Sep.


Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates.

Simoni Y, Becht E, Fehlings M, Loh CY, Koo SL, Teng KWW, Yeong JPS, Nahar R, Zhang T, Kared H, Duan K, Ang N, Poidinger M, Lee YY, Larbi A, Khng AJ, Tan E, Fu C, Mathew R, Teo M, Lim WT, Toh CK, Ong BH, Koh T, Hillmer AM, Takano A, Lim TKH, Tan EH, Zhai W, Tan DSW, Tan IB, Newell EW.

Nature. 2018 May;557(7706):575-579. doi: 10.1038/s41586-018-0130-2. Epub 2018 May 16.


Occurrence and characteristics of extended-spectrum β-lactamase- and carbapenemase- producing bacteria from hospital effluents in Singapore.

Haller L, Chen H, Ng C, Le TH, Koh TH, Barkham T, Sobsey M, Gin KY.

Sci Total Environ. 2018 Feb 15;615:1119-1125. doi: 10.1016/j.scitotenv.2017.09.217. Epub 2017 Oct 17.


Advanced analyses of computed tomography coronary angiography can help discriminate ischemic lesions.

Zhang JM, Shuang D, Baskaran L, Wu W, Teo SK, Huang W, Gobeawan L, Allen JC, Tan RS, Su X, Ismail NB, Wan M, Su B, Zou H, Low R, Zhao X, Chi Y, Zhou J, Su Y, Lomarda AM, Chin CY, Fam JM, Keng FYJ, Wong ASL, Tan JWC, Yeo KK, Wong PEH, Chin CT, Ho KW, Yap J, Kassab GS, Chua T, Koh TH, Tan SY, Lim ST, Zhong L.

Int J Cardiol. 2018 Sep 15;267:208-214. doi: 10.1016/j.ijcard.2018.04.020. Epub 2018 Apr 26.


[A Case of Laparoscopic Hartmann's Operation for Perforation of Rectal Cancer in Superior Elderly People].

Sakai T, Soga K, Mizutani T, Kato S, Hirashima S, Nishio M, Koh T, Oguro A, Nakagawa N.

Gan To Kagaku Ryoho. 2018 Mar;45(3):486-488. Japanese.


Comparison of Clinical Isolates of Aeromonas from Singapore and Malaysia with Regard to Molecular Identification, Virulence, and Antimicrobial Profiles.

Khor WC, Puah SM, Koh TH, Tan JAMA, Puthucheary SD, Chua KH.

Microb Drug Resist. 2018 May;24(4):469-478. doi: 10.1089/mdr.2017.0083. Epub 2018 Feb 20.


Corrigendum: Characterization of Metagenomes in Urban Aquatic Compartments Reveals High Prevalence of Clinically Relevant Antibiotic Resistance Genes in Wastewaters.

Ng C, Tay M, Tan B, Le TH, Haller L, Chen H, Koh TH, Barkham TMS, Thompson JR, Gin KY.

Front Microbiol. 2018 Feb 5;9:175. doi: 10.3389/fmicb.2018.00175. eCollection 2018.


Coronary and arch hybrid surgery in a patient with infrarenal aortic occlusion.

Koh TK, Ting JZL, Wee B, Khamitov R, Teoh K, Wong J, Sorokin VA.

Asian Cardiovasc Thorac Ann. 2018 Feb;26(2):148-150. doi: 10.1177/0218492318755181. Epub 2018 Jan 16.


Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing.

Nahar R, Zhai W, Zhang T, Takano A, Khng AJ, Lee YY, Liu X, Lim CH, Koh TPT, Aung ZW, Lim TKH, Veeravalli L, Yuan J, Teo ASM, Chan CX, Poh HM, Chua IML, Liew AA, Lau DPX, Kwang XL, Toh CK, Lim WT, Lim B, Tam WL, Tan EH, Hillmer AM, Tan DSW.

Nat Commun. 2018 Jan 15;9(1):216. doi: 10.1038/s41467-017-02584-z.


Draft Genome Sequence of Singapore Klebsiella pneumoniae subsp. pneumoniae Isolate DS32358_14, Which Contains the Carbapenemase Gene blaVIM-1.

Koh TH, Abdul Rahman NB, Teo JWP, La MV, Periaswamy B, Chen SL.

Genome Announc. 2018 Jan 4;6(1). pii: e01377-17. doi: 10.1128/genomeA.01377-17.


Nod2 is required for the early innate immune clearance of Acinetobacter baumannii from the lungs.

Kale SD, Dikshit N, Kumar P, Balamuralidhar V, Khameneh HJ, Bin Abdul Malik N, Koh TH, Tan GGY, Tan TT, Mortellaro A, Sukumaran B.

Sci Rep. 2017 Dec 12;7(1):17429. doi: 10.1038/s41598-017-17653-y.


Thrombospondin-1 and disease progression in dysferlinopathy.

Urao N, Mirza RE, Corbiere TF, Hollander Z, Borchers CH, Koh TJ.

Hum Mol Genet. 2017 Dec 15;26(24):4951-4960. doi: 10.1093/hmg/ddx378.


Characterization of Metagenomes in Urban Aquatic Compartments Reveals High Prevalence of Clinically Relevant Antibiotic Resistance Genes in Wastewaters.

Ng C, Tay M, Tan B, Le TH, Haller L, Chen H, Koh TH, Barkham TMS, Gin KY.

Front Microbiol. 2017 Nov 16;8:2200. doi: 10.3389/fmicb.2017.02200. eCollection 2017. Erratum in: Front Microbiol. 2018 Feb 05;9:175.


Utility of Laparoscopic Subtotal Cholecystectomy with or without Cystic Duct Ligation for Severe Cholecystitis.

Hirajima S, Koh T, Sakai T, Imamura T, Kato S, Nishimura Y, Soga K, Nishio M, Oguro A, Nakagawa N.

Am Surg. 2017 Nov 1;83(11):1209-1213.


Design of a Soft Robotic Elbow Sleeve with Passive and Intent-Controlled Actuation.

Koh TH, Cheng N, Yap HK, Yeow CH.

Front Neurosci. 2017 Oct 25;11:597. doi: 10.3389/fnins.2017.00597. eCollection 2017.


Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying blaIMI-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore.

Koh TH, Rahman NBA, Teo JWP, La MV, Periaswamy B, Chen SL.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01542-17. doi: 10.1128/AAC.01542-17. Print 2018 Jan.


MR diffusion kurtosis imaging predicts malignant potential and the histological type of meningioma.

Xing F, Tu N, Koh TS, Wu G.

Eur J Radiol. 2017 Oct;95:286-292. doi: 10.1016/j.ejrad.2017.08.019. Epub 2017 Aug 24.


Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in retail food in Singapore.

Aung KT, Hsu LY, Koh TH, Hapuarachchi HC, Chau ML, Gutiérrez RA, Ng LC.

Antimicrob Resist Infect Control. 2017 Sep 8;6:94. doi: 10.1186/s13756-017-0255-3. eCollection 2017.


Comparative analysis of recurrent events after presentation with an index myocardial infarction or ischaemic stroke.

Yeo KK, Zheng H, Chow KY, Ahmad A, Chan BPL, Chang HM, Chong E, Chua TSJ, Foo DCG, Low LP, Ong MEH, Ong HY, Koh TH, Tan HC, Tang KF, Venketasubramanian N.

Eur Heart J Qual Care Clin Outcomes. 2017 Jul 1;3(3):234-242. doi: 10.1093/ehjqcco/qcw048.


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