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Items: 1 to 50 of 56

1.

Lofexidine versus diazepam for the treatment of opioid withdrawal syndrome: A double-blind randomized clinical trial in Singapore.

Guo S, Manning V, Yang Y, Koh PK, Chan E, de Souza NN, Assam PN, Sultana R, Wijesinghe R, Pangjaya J, Kandasami G, Cheok C, Lee KM, Wong KE.

J Subst Abuse Treat. 2018 Aug;91:1-11. doi: 10.1016/j.jsat.2018.04.012. Epub 2018 Apr 25.

PMID:
29910009
2.

Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.

Kong SL, Liu X, Suhaimi NM, Koh KJH, Hu M, Lee DYS, Cima I, Phyo WM, Lee EXW, Tai JA, Foong YM, Vo JH, Koh PK, Zhang T, Ying JY, Lim B, Tan MH, Hillmer AM.

Oncotarget. 2017 Jul 10;8(40):68026-68037. doi: 10.18632/oncotarget.19138. eCollection 2017 Sep 15.

3.

Metformin Inhibits Cellular Proliferation and Bioenergetics in Colorectal Cancer Patient-Derived Xenografts.

Mohamed Suhaimi NA, Phyo WM, Yap HY, Choy SHY, Wei X, Choudhury Y, Tan WJ, Tan LAPY, Foo RSY, Tan SHS, Tiang Z, Wong CF, Koh PK, Tan MH.

Mol Cancer Ther. 2017 Sep;16(9):2035-2044. doi: 10.1158/1535-7163.MCT-16-0793. Epub 2017 May 22.

4.

Tumor-derived circulating endothelial cell clusters in colorectal cancer.

Cima I, Kong SL, Sengupta D, Tan IB, Phyo WM, Lee D, Hu M, Iliescu C, Alexander I, Goh WL, Rahmani M, Suhaimi NA, Vo JH, Tai JA, Tan JH, Chua C, Ten R, Lim WJ, Chew MH, Hauser CA, van Dam RM, Lim WY, Prabhakar S, Lim B, Koh PK, Robson P, Ying JY, Hillmer AM, Tan MH.

Sci Transl Med. 2016 Jun 29;8(345):345ra89. doi: 10.1126/scitranslmed.aad7369.

PMID:
27358499
5.

An experience with video-assisted anal fistula treatment (VAAFT) with new insights into the treatment of anal fistulae.

Seow-En I, Seow-Choen F, Koh PK.

Tech Coloproctol. 2016 Jun;20(6):389-393. doi: 10.1007/s10151-016-1450-6. Epub 2016 Apr 8.

PMID:
27059492
6.

Prevalence of KRAS, BRAF, PI3K and EGFR mutations among Asian patients with metastatic colorectal cancer.

Phua LC, Ng HW, Yeo AH, Chen E, Lo MS, Cheah PY, Chan EC, Koh PK, Ho HK.

Oncol Lett. 2015 Oct;10(4):2519-2526. Epub 2015 Aug 3.

7.

Asia-Pacific consensus statements on Crohn's disease. Part 2: Management.

Ooi CJ, Makharia GK, Hilmi I, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, Sollano J, Manatsathit S, de Silva HJ, Rerknimitr R, Pisespongsa P, Abu Hassan MR, Sung J, Hibi T, Boey CC, Moran N, Leong RW; Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease.

J Gastroenterol Hepatol. 2016 Jan;31(1):56-68. doi: 10.1111/jgh.12958. Review.

PMID:
25819311
8.

Asia Pacific Consensus Statements on Crohn's disease. Part 1: Definition, diagnosis, and epidemiology: (Asia Pacific Crohn's Disease Consensus--Part 1).

Ooi CJ, Makharia GK, Hilmi I, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, Sollano J, Manatsathit S, de Silva HJ, Rerknimitr R, Pisespongsa P, Abu Hassan MR, Sung J, Hibi T, Boey CC, Moran N, Leong RW; Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease.

J Gastroenterol Hepatol. 2016 Jan;31(1):45-55. doi: 10.1111/jgh.12956. Review.

PMID:
25819140
9.

Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.

Mohamed Suhaimi NA, Foong YM, Lee DY, Phyo WM, Cima I, Lee EX, Goh WL, Lim WY, Chia KS, Kong SL, Gong M, Lim B, Hillmer AM, Koh PK, Ying JY, Tan MH.

Mol Oncol. 2015 Apr;9(4):850-60. doi: 10.1016/j.molonc.2014.12.011. Epub 2015 Jan 7.

10.

Suicidal ideation and lifetime attempts in substance and gambling disorders.

Manning V, Koh PK, Yang Y, Ng A, Guo S, Kandasami G, Wong KE.

Psychiatry Res. 2015 Feb 28;225(3):706-9. doi: 10.1016/j.psychres.2014.11.011. Epub 2014 Nov 15.

PMID:
25555417
11.

Pathological gamblers in Singapore: treatment response at 3 months.

Manning V, Ng A, Koh PK, Guo S, Gomathinayagam K, Wong KE.

J Addict Med. 2014 Nov-Dec;8(6):462-9. doi: 10.1097/ADM.0000000000000082.

PMID:
25303985
12.

Global fecal microRNA profiling in the identification of biomarkers for colorectal cancer screening among Asians.

Phua LC, Chue XP, Koh PK, Cheah PY, Chan EC, Ho HK.

Oncol Rep. 2014 Jul;32(1):97-104. doi: 10.3892/or.2014.3193. Epub 2014 May 16.

PMID:
24841830
13.

Systematic study on genetic and epimutational profile of a cohort of Amsterdam criteria-defined Lynch Syndrome in Singapore.

Liu Y, Chew MH, Goh XW, Tan SY, Loi CT, Tan YM, Law HY, Koh PK, Tang CL.

PLoS One. 2014 Apr 7;9(4):e94170. doi: 10.1371/journal.pone.0094170. eCollection 2014.

14.

Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone.

Trigonis I, Koh PK, Taylor B, Tamal M, Ryder D, Earl M, Anton-Rodriguez J, Haslett K, Young H, Faivre-Finn C, Blackhall F, Jackson A, Asselin MC.

Eur J Nucl Med Mol Imaging. 2014 Apr;41(4):682-93. doi: 10.1007/s00259-013-2632-3. Epub 2014 Feb 7.

15.

Non-invasive fecal metabonomic detection of colorectal cancer.

Phua LC, Chue XP, Koh PK, Cheah PY, Ho HK, Chan EC.

Cancer Biol Ther. 2014 Apr;15(4):389-97. doi: 10.4161/cbt.27625. Epub 2014 Jan 14.

16.

A novel indel in exon 9 of APC upregulates a 'skip exon 9' isoform and causes very severe familial adenomatous polyposis.

Cheah PY, Wong YH, Koh PK, Loi C, Chew MH, Tang CL.

Eur J Hum Genet. 2014 Jun;22(6):833-6. doi: 10.1038/ejhg.2013.245. Epub 2013 Oct 30.

17.

Global gas chromatography/time-of-flight mass spectrometry (GC/TOFMS)-based metabonomic profiling of lyophilized human feces.

Phua LC, Koh PK, Cheah PY, Ho HK, Chan EC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Oct 15;937:103-13. doi: 10.1016/j.jchromb.2013.08.025. Epub 2013 Aug 26.

PMID:
24029555
18.

Mismatch repair deficiency screening via immunohistochemical staining in young Asians with colorectal cancers.

Chew MH, Koh PK, Tan M, Lim KH, Carol L, Tang CL.

World J Surg. 2013 Oct;37(10):2468-75. doi: 10.1007/s00268-013-2134-2.

PMID:
23887594
19.

Young colorectal carcinoma patients do not have a poorer prognosis: a comparative review of 2,426 cases.

Yeo SA, Chew MH, Koh PK, Tang CL.

Tech Coloproctol. 2013 Dec;17(6):653-61. doi: 10.1007/s10151-013-0977-z. Epub 2013 Mar 5.

PMID:
23460362
20.

Localized gastrointestinal stromal tumor of the rectum: An uncommon primary site with prominent disease and treatment-related morbidities.

Farid M, Lee MJ, Chew MH, Ong WS, Sairi AN, Foo KF, Choo SP, Koo WH, Ong S, Koh PK, Quek R.

Mol Clin Oncol. 2013 Jan;1(1):190-194. Epub 2012 Sep 19.

21.

Investigating the role of nucleoside transporters in the resistance of colorectal cancer to 5-fluorouracil therapy.

Phua LC, Mal M, Koh PK, Cheah PY, Chan EC, Ho HK.

Cancer Chemother Pharmacol. 2013 Mar;71(3):817-23. doi: 10.1007/s00280-012-2054-0. Epub 2012 Dec 28.

PMID:
23271323
22.

The classification of intestinal polyposis.

Cheah PY, Lim KH, Koh PK, Tang CL.

Nat Genet. 2013 Jan;45(1):2. doi: 10.1038/ng.2474. No abstract available.

PMID:
23268127
23.

Caesarean section scar pregnancy: a case series at a single tertiary centre.

Pang YP, Tan WC, Yong TT, Koh PK, Tan HK, Ho TH.

Singapore Med J. 2012 Oct;53(10):638-42.

24.

Treatment outcome and its predictors among Asian problem drinkers.

Manning V, Gomez B, Koh PK, Ng A, Guo S, Kandasami G, Wong KE.

Drug Alcohol Rev. 2013 Mar;32(2):178-86. doi: 10.1111/j.1465-3362.2012.00518.x. Epub 2012 Oct 9.

PMID:
23043535
25.

Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.

Thean LF, Li HH, Teo YY, Koh WP, Yuan JM, Teoh ML, Koh PK, Tang CL, Cheah PY.

PLoS One. 2012;7(8):e42407. doi: 10.1371/journal.pone.0042407. Epub 2012 Aug 3.

26.

Metabotyping of human colorectal cancer using two-dimensional gas chromatography mass spectrometry.

Mal M, Koh PK, Cheah PY, Chan EC.

Anal Bioanal Chem. 2012 Apr;403(2):483-93. doi: 10.1007/s00216-012-5870-5. Epub 2012 Feb 29.

PMID:
22374317
27.
28.

Familial colorectal cancer type X: polyp burden and cancer risk stratification via a family history score.

Koh PK, Kalady M, Skacel M, Fay S, McGannon E, Shenal J, Arroyo L, Toderick K, Church J.

ANZ J Surg. 2011 Jul-Aug;81(7-8):537-42.

PMID:
22295380
29.

Targeted agents in non-small cell lung cancer (NSCLC): clinical developments and rationale for the combination with thoracic radiotherapy.

Koh PK, Faivre-Finn C, Blackhall FH, De Ruysscher D.

Cancer Treat Rev. 2012 Oct;38(6):626-40. doi: 10.1016/j.ctrv.2011.11.003. Epub 2011 Dec 22. Review.

PMID:
22196919
30.

Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response.

Ong SM, Tan YC, Beretta O, Jiang D, Yeap WH, Tai JJ, Wong WC, Yang H, Schwarz H, Lim KH, Koh PK, Ling KL, Wong SC.

Eur J Immunol. 2012 Jan;42(1):89-100. doi: 10.1002/eji.201141825. Epub 2011 Dec 12.

31.

Stage IV colorectal cancers: an analysis of factors predicting outcome and survival in 728 cases.

Chew MH, Teo JY, Kabir T, Koh PK, Eu KW, Tang CL.

J Gastrointest Surg. 2012 Mar;16(3):603-12. doi: 10.1007/s11605-011-1725-1. Epub 2011 Oct 19.

PMID:
22009464
32.

Ultra-pressure liquid chromatography/tandem mass spectrometry targeted profiling of arachidonic acid and eicosanoids in human colorectal cancer.

Mal M, Koh PK, Cheah PY, Chan EC.

Rapid Commun Mass Spectrom. 2011 Mar 30;25(6):755-64. doi: 10.1002/rcm.4926.

PMID:
21337637
33.

Critical analysis of mucin and signet ring cell as prognostic factors in an Asian population of 2,764 sporadic colorectal cancers.

Chew MH, Yeo SA, Ng ZP, Lim KH, Koh PK, Ng KH, Eu KW.

Int J Colorectal Dis. 2010 Oct;25(10):1221-9. doi: 10.1007/s00384-010-1033-3. Epub 2010 Aug 5.

PMID:
20686777
34.

A 'metastasis-prone' signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics.

Hong Y, Downey T, Eu KW, Koh PK, Cheah PY.

Clin Exp Metastasis. 2010 Feb;27(2):83-90. doi: 10.1007/s10585-010-9305-4. Epub 2010 Feb 9.

PMID:
20143136
35.

Peutz-Jeghers syndrome: data from the Singapore Polyposis Registry and a shifting paradigm in management.

Tan VK, Koh PK, Loi CT, Eu KW, Tang CL.

Ann Acad Med Singapore. 2010 Jan;39(1):17-21.

36.

The use of treosulfan and gemcitabine in the treatment of platinum-resistant ovarian cancer.

Hilman S, Koh PK, Collins S, Allerton R.

Oncol Lett. 2010 Jan;1(1):209-213. Epub 2010 Jan 1.

37.

Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients.

Thean LF, Loi C, Ho KS, Koh PK, Eu KW, Cheah PY.

Genes Chromosomes Cancer. 2010 Feb;49(2):99-106. doi: 10.1002/gcc.20724.

PMID:
19847890
38.

Germline bone morphogenesis protein receptor 1A mutation causes colorectal tumorigenesis in hereditary mixed polyposis syndrome.

Cheah PY, Wong YH, Chau YP, Loi C, Lim KH, Lim JF, Koh PK, Eu KW.

Am J Gastroenterol. 2009 Dec;104(12):3027-33. doi: 10.1038/ajg.2009.542. Epub 2009 Sep 22.

PMID:
19773747
39.

Improved survival in an Asian cohort of young colorectal cancer patients: an analysis of 523 patients from a single institution.

Chew MH, Koh PK, Ng KH, Eu KW.

Int J Colorectal Dis. 2009 Sep;24(9):1075-83. doi: 10.1007/s00384-009-0701-7. Epub 2009 Apr 23.

PMID:
19387661
40.

Novel human pathological mutations. Gene symbol: APC. Disease: adenomatous polyposis coli.

Cheah PY, Wong YH, Loi C, Koh PK, Eu KW.

Hum Genet. 2009 Apr;125(3):352. No abstract available.

PMID:
19320041
41.

Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue.

Mal M, Koh PK, Cheah PY, Chan EC.

Rapid Commun Mass Spectrom. 2009 Feb;23(4):487-94. doi: 10.1002/rcm.3898.

PMID:
19140133
42.

Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS).

Chan EC, Koh PK, Mal M, Cheah PY, Eu KW, Backshall A, Cavill R, Nicholson JK, Keun HC.

J Proteome Res. 2009 Jan;8(1):352-61. doi: 10.1021/pr8006232.

PMID:
19063642
43.

Phenotypic characteristics of hereditary non-polyposis colorectal cancer by the Amsterdam criteria: an Asian perspective.

Chew MH, Koh PK, Ng KH, Lim JF, Ho KS, Ooi BS, Tang CL, Eu KW.

ANZ J Surg. 2008 Jul;78(7):556-60. doi: 10.1111/j.1445-2197.2008.04570.x.

PMID:
18593409
44.

Ileo-anal j-pouch cancer: an unusual case in an unusual location.

Koh PK, Doumit J, Downs-Kelly E, Bronner MP, Salimi R, Fazio VW, Vogel JD.

Tech Coloproctol. 2008 Dec;12(4):341-5. doi: 10.1007/s10151-008-0420-z. Epub 2008 Jun 10. Review.

PMID:
18545871
45.

Modest promoter methylation of E-cadherin gene in sporadic colorectal cancers: a quantitative analysis.

Liu Y, Zhao Y, Wu C, Ho KS, Koh PK, Chong SF, Eu KW.

Cancer Biomark. 2008;4(2):111-20.

PMID:
18503162
46.

A novel method of dealing with a large rectal enterotomy in an irradiated pelvis.

Wong NY, Koh PK, Eu KW.

Tech Coloproctol. 2007 Dec;11(4):350-2. doi: 10.1007/s10151-007-0380-8. Epub 2007 Nov 30.

PMID:
18209949
47.

Mesenteric desmoid tumors in Singapore familial adenomatous polyposis patients: clinical course and genetic profile in a predominantly Chinese population.

Koh PK, Loi C, Cao X, Cheah PY, Ho KS, Ooi BS, Tang CL, Eu KW.

Dis Colon Rectum. 2007 Jan;50(1):75-82.

PMID:
17082890
48.

A systematic review of the function and complications of colonic pouches.

Koh PK, Tang CL, Eu KW, Samuel M, Chan E.

Int J Colorectal Dis. 2007 May;22(5):543-8. Epub 2006 Sep 13. Review.

PMID:
16969678
49.

Multicentre prospective randomized trials are not always relevant to surgeons.

Koh PK, Seow-Choen F.

ANZ J Surg. 2006 May;76(5):286-7. Review. No abstract available.

PMID:
16768681
50.

Total mesorectal excision: the unrecognized pelvic plane.

Koh PK, Seow-Choen F, Kwek BH.

Dis Colon Rectum. 2006 Feb;49(2):280-3; discussion 283-4.

PMID:
16322966

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