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Items: 15


Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.

Boretto M, Maenhoudt N, Luo X, Hennes A, Boeckx B, Bui B, Heremans R, Perneel L, Kobayashi H, Van Zundert I, Brems H, Cox B, Ferrante M, Uji-I H, Koh KP, D'Hooghe T, Vanhie A, Vergote I, Meuleman C, Tomassetti C, Lambrechts D, Vriens J, Timmerman D, Vankelecom H.

Nat Cell Biol. 2019 Aug;21(8):1041-1051. doi: 10.1038/s41556-019-0360-z. Epub 2019 Aug 1.


Lineage-specific functions of TET1 in the postimplantation mouse embryo.

Khoueiry R, Sohni A, Thienpont B, Luo X, Velde JV, Bartoccetti M, Boeckx B, Zwijsen A, Rao A, Lambrechts D, Koh KP.

Nat Genet. 2017 Jul;49(7):1061-1072. doi: 10.1038/ng.3868. Epub 2017 May 15.


PDGFRα+ Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors.

Lo Nigro A, de Jaime-Soguero A, Khoueiry R, Cho DS, Ferlazzo GM, Perini I, Abon Escalona V, Aranguren XL, Chuva de Sousa Lopes SM, Koh KP, Conaldi PG, Hu WS, Zwijsen A, Lluis F, Verfaillie CM.

Stem Cell Reports. 2017 Feb 14;8(2):318-333. doi: 10.1016/j.stemcr.2016.12.010. Epub 2017 Jan 12.


Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation.

Sohni A, Bartoccetti M, Khoueiry R, Spans L, Vande Velde J, De Troyer L, Pulakanti K, Claessens F, Rao S, Koh KP.

Mol Cell Biol. 2015 Mar;35(6):1026-42. doi: 10.1128/MCB.01172-14. Epub 2015 Jan 12.


Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A.

Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.


DNA methylation and methylcytosine oxidation in cell fate decisions.

Koh KP, Rao A.

Curr Opin Cell Biol. 2013 Apr;25(2):152-61. doi: 10.1016/ Epub 2013 Mar 14. Review.


Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.

Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A.

Cell Stem Cell. 2011 Feb 4;8(2):200-13. doi: 10.1016/j.stem.2011.01.008.


Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A.

Nature. 2010 Dec 9;468(7325):839-43. doi: 10.1038/nature09586.


Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3.

Koh KP, Sundrud MS, Rao A.

PLoS One. 2009 Dec 1;4(12):e8109. doi: 10.1371/journal.pone.0008109.


Effect of intradialytic versus home-based aerobic exercise training on physical function and vascular parameters in hemodialysis patients: a randomized pilot study.

Koh KP, Fassett RG, Sharman JE, Coombes JS, Williams AD.

Am J Kidney Dis. 2010 Jan;55(1):88-99. doi: 10.1053/j.ajkd.2009.09.025. Epub 2009 Nov 22.


Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A.

Science. 2009 May 15;324(5929):930-5. doi: 10.1126/science.1170116. Epub 2009 Apr 16.


Intradialytic versus home-based exercise training in hemodialysis patients: a randomised controlled trial.

Koh KP, Fassett RG, Sharman JE, Coombes JS, Williams AD.

BMC Nephrol. 2009 Jan 29;10:2. doi: 10.1186/1471-2369-10-2.


Human allograft arterial injury is ameliorated by sirolimus and cyclosporine and correlates with suppression of interferon-gamma.

Yi T, Cuchara L, Wang Y, Koh KP, Ranjbaran H, Tellides G, Pober JS, Lorber MI.

Transplantation. 2006 Feb 27;81(4):559-66.


T cell-mediated vascular dysfunction of human allografts results from IFN-gamma dysregulation of NO synthase.

Koh KP, Wang Y, Yi T, Shiao SL, Lorber MI, Sessa WC, Tellides G, Pober JS.

J Clin Invest. 2004 Sep;114(6):846-56.


T lymphocyte-endothelial cell interactions.

Choi J, Enis DR, Koh KP, Shiao SL, Pober JS.

Annu Rev Immunol. 2004;22:683-709. Review.


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