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Items: 23


Activation of dendritic cells by targeted DNA: a potential addition to the armamentarium for anti-cancer immunotherapy.

Fyrstenberg Laursen M, Kofod-Olsen E, Agger R.

Cancer Immunol Immunother. 2019 Nov;68(11):1875-1880. doi: 10.1007/s00262-019-02400-1. Epub 2019 Sep 26. Review.


CD11c-targeted Delivery of DNA to Dendritic Cells Leads to cGAS- and STING-dependent Maturation.

Laursen MF, Christensen E, Degn LLT, Jønsson K, Jakobsen MR, Agger R, Kofod-Olsen E.

J Immunother. 2018 Jan;41(1):9-18. doi: 10.1097/CJI.0000000000000195.


Ectodermal dysplasia with immunodeficiency caused by a branch-point mutation in IKBKG/NEMO.

Jørgensen SE, Bøttger P, Kofod-Olsen E, Holm M, Mørk N, Ørntoft TF, Sørensen UBS, Bernth-Jensen JM, Herlin T, Veirum J, Larsen CS, Østergaard L, Hartmann R, Christiansen M, Mogensen TH.

J Allergy Clin Immunol. 2016 Dec;138(6):1706-1709.e4. doi: 10.1016/j.jaci.2016.05.030. Epub 2016 Jun 29. No abstract available.


Altered fraction of regulatory B and T cells is correlated with autoimmune phenomena and splenomegaly in patients with CVID.

Kofod-Olsen E, Jørgensen SE, Nissen SK, Westh L, Møller BK, Østergaard L, Larsen CS, Mogensen TH.

Clin Immunol. 2016 Jan;162:49-57. doi: 10.1016/j.clim.2015.11.003. Epub 2015 Nov 14.


Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis.

Mørk N, Kofod-Olsen E, Sørensen KB, Bach E, Ørntoft TF, Østergaard L, Paludan SR, Christiansen M, Mogensen TH.

Genes Immun. 2015 Dec;16(8):552-66. doi: 10.1038/gene.2015.46. Epub 2015 Oct 29.


A STAT1-gain-of-function mutation causing Th17 deficiency with chronic mucocutaneous candidiasis, psoriasiform hyperkeratosis and dermatophytosis.

Nielsen J, Kofod-Olsen E, Spaun E, Larsen CS, Christiansen M, Mogensen TH.

BMJ Case Rep. 2015 Oct 22;2015. pii: bcr2015211372. doi: 10.1136/bcr-2015-211372. Erratum in: BMJ Case Rep. 2015;2015. pii: bcr2015211372corr1. doi: 10.1136/bcr-2015-211372corr1.


Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

Andersen LL, Mørk N, Reinert LS, Kofod-Olsen E, Narita R, Jørgensen SE, Skipper KA, Höning K, Gad HH, Østergaard L, Ørntoft TF, Hornung V, Paludan SR, Mikkelsen JG, Fujita T, Christiansen M, Hartmann R, Mogensen TH.

J Exp Med. 2015 Aug 24;212(9):1371-9. doi: 10.1084/jem.20142274. Epub 2015 Jul 27.


The DR6 protein from human herpesvirus-6B induces p53-independent cell cycle arrest in G2/M.

Schleimann MH, Hoberg S, Solhøj Hansen A, Bundgaard B, Witt CT, Kofod-Olsen E, Höllsberg P.

Virology. 2014 Mar;452-453:254-63. doi: 10.1016/j.virol.2014.01.028. Epub 2014 Feb 17.


Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates with chronic immune activation.

Nissen SK, Højen JF, Andersen KL, Kofod-Olsen E, Berg RK, Paludan SR, Østergaard L, Jakobsen MR, Tolstrup M, Mogensen TH.

Clin Exp Immunol. 2014 Jul;177(1):295-309. doi: 10.1111/cei.12317.


T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication.

Berg RK, Rahbek SH, Kofod-Olsen E, Holm CK, Melchjorsen J, Jensen DG, Hansen AL, Jørgensen LB, Ostergaard L, Tolstrup M, Larsen CS, Paludan SR, Jakobsen MR, Mogensen TH.

PLoS One. 2014 Jan 3;9(1):e84513. doi: 10.1371/journal.pone.0084513. eCollection 2014.


Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization.

Kofod-Olsen E, Pettersson S, Wallace M, Abduljabar AB, Oster B, Hupp T, Höllsberg P.

Virology. 2014 Jan 5;448:33-42. doi: 10.1016/j.virol.2013.10.002. Epub 2013 Oct 18.


The B1-cell subpopulation is diminished in patients with relapsing-remitting multiple sclerosis.

Tørring C, Petersen CC, Bjerg L, Kofod-Olsen E, Petersen T, Höllsberg P.

J Neuroimmunol. 2013 Sep 15;262(1-2):92-9. doi: 10.1016/j.jneuroim.2013.06.002. Epub 2013 Jul 12.


Inhibition of p53-dependent, but not p53-independent, cell death by U19 protein from human herpesvirus 6B.

Kofod-Olsen E, Møller JM, Schleimann MH, Bundgaard B, Bak RO, Øster B, Mikkelsen JG, Hupp T, Höllsberg P.

PLoS One. 2013;8(3):e59223. doi: 10.1371/journal.pone.0059223. Epub 2013 Mar 26.


Human herpesvirus-6A/B binds to spermatozoa acrosome and is the most prevalent herpesvirus in semen from sperm donors.

Kaspersen MD, Larsen PB, Kofod-Olsen E, Fedder J, Bonde J, Höllsberg P.

PLoS One. 2012;7(11):e48810. doi: 10.1371/journal.pone.0048810. Epub 2012 Nov 7.


U20 is responsible for human herpesvirus 6B inhibition of tumor necrosis factor receptor-dependent signaling and apoptosis.

Kofod-Olsen E, Ross-Hansen K, Schleimann MH, Jensen DK, Møller JM, Bundgaard B, Mikkelsen JG, Höllsberg P.

J Virol. 2012 Nov;86(21):11483-92. doi: 10.1128/JVI.00847-12. Epub 2012 Aug 15.


Targeted genome editing by recombinant adeno-associated virus (rAAV) vectors for generating genetically modified pigs.

Luo Y, Kofod-Olsen E, Christensen R, Sørensen CB, Bolund L.

J Genet Genomics. 2012 Jun 20;39(6):269-74. doi: 10.1016/j.jgg.2012.05.004. Epub 2012 May 18. Review.


Human herpesvirus 6B induces phenotypic maturation without IL-10 and IL-12p70 production in dendritic cells.

Bertelsen LB, Petersen CC, Kofod-Olsen E, Oster B, Höllsberg P, Agger R, Hokland M.

Scand J Immunol. 2010 Jun;71(6):431-9. doi: 10.1111/j.1365-3083.2010.02389.x.


Expression of MDC/CCL22 and its receptor CCR4 in rheumatoid arthritis, psoriatic arthritis and osteoarthritis.

Flytlie HA, Hvid M, Lindgreen E, Kofod-Olsen E, Petersen EL, Jørgensen A, Deleuran M, Vestergaard C, Deleuran B.

Cytokine. 2010 Jan;49(1):24-9. doi: 10.1016/j.cyto.2009.10.005. Epub 2009 Nov 25.


Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41.

Schleimann MH, Møller JM, Kofod-Olsen E, Höllsberg P.

PLoS One. 2009 Oct 15;4(10):e7457. doi: 10.1371/journal.pone.0007457.


Osteopontin enhances phagocytosis through a novel osteopontin receptor, the alphaXbeta2 integrin.

Schack L, Stapulionis R, Christensen B, Kofod-Olsen E, Skov Sørensen UB, Vorup-Jensen T, Sørensen ES, Höllsberg P.

J Immunol. 2009 Jun 1;182(11):6943-50. doi: 10.4049/jimmunol.0900065.


Restriction of human herpesvirus 6B replication by p53.

Oster B, Kofod-Olsen E, Bundgaard B, Höllsberg P.

J Gen Virol. 2008 May;89(Pt 5):1106-13. doi: 10.1099/vir.0.83262-0.


Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner.

Kofod-Olsen E, Ross-Hansen K, Mikkelsen JG, Höllsberg P.

J Gen Virol. 2008 Jan;89(Pt 1):106-16.


Human herpesvirus 6B inhibits cell proliferation by a p53-independent pathway.

Øster B, Kaspersen MD, Kofod-Olsen E, Bundgaard B, Höllsberg P.

J Clin Virol. 2006 Dec;37 Suppl 1:S63-8.


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