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Items: 1 to 50 of 99

1.

Engineering Corynebacterium glutamicum for the de novo biosynthesis of tailored poly-γ-glutamic acid.

Xu G, Zha J, Cheng H, Ibrahim MHA, Yang F, Dalton H, Cao R, Zhu Y, Fang J, Chi K, Zheng P, Zhang X, Shi J, Xu Z, Gross RA, Koffas MAG.

Metab Eng. 2019 Aug 23;56:39-49. doi: 10.1016/j.ymben.2019.08.011. [Epub ahead of print]

PMID:
31449877
2.

Design and Characterization of Biosensors for the Screening of Modular Assembled Naringenin Biosynthetic Library in Saccharomyces cerevisiae.

Wang R, Cress BF, Yang Z, Hordines JC 3rd, Zhao S, Jung GY, Wang Z, Koffas MAG.

ACS Synth Biol. 2019 Sep 20;8(9):2121-2130. doi: 10.1021/acssynbio.9b00212. Epub 2019 Aug 28.

PMID:
31433622
3.

Reducing Staphylococcus aureus resistance to lysostaphin using CRISPR-dCas9.

Wu X, Zha J, Koffas MAG, Dordick JS.

Biotechnol Bioeng. 2019 Aug 21. doi: 10.1002/bit.27143. [Epub ahead of print]

PMID:
31433061
4.

Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2.

Williams A, Gedeon KS, Vaidyanathan D, Yu Y, Collins CH, Dordick JS, Linhardt RJ, Koffas MAG.

Microb Cell Fact. 2019 Aug 12;18(1):132. doi: 10.1186/s12934-019-1187-9.

5.

Increased 3'-Phosphoadenosine-5'-phosphosulfate Levels in Engineered Escherichia coli Cell Lysate Facilitate the In Vitro Synthesis of Chondroitin Sulfate A.

Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG.

Biotechnol J. 2019 Sep;14(9):e1800436. doi: 10.1002/biot.201800436. Epub 2019 Jul 1.

PMID:
31180182
6.

Production of pyranoanthocyanins using Escherichia coli co-cultures.

Akdemir H, Silva A, Zha J, Zagorevski DV, Koffas MAG.

Metab Eng. 2019 Sep;55:290-298. doi: 10.1016/j.ymben.2019.05.008. Epub 2019 May 21.

PMID:
31125607
7.

In Vitro Naringenin Biosynthesis from p-Coumaric Acid Using Recombinant Enzymes.

Zang Y, Zha J, Wu X, Zheng Z, Ouyang J, Koffas MAG.

J Agric Food Chem. 2019 Apr 8. doi: 10.1021/acs.jafc.9b00413. [Epub ahead of print]

PMID:
30919618
8.

Heavy Heparin: A Stable Isotope-Enriched, Chemoenzymatically-Synthesized, Poly-Component Drug.

Cress BF, Bhaskar U, Vaidyanathan D, Williams A, Cai C, Liu X, Fu L, M-Chari V, Zhang F, Mousa SA, Dordick JS, Koffas MAG, Linhardt RJ.

Angew Chem Int Ed Engl. 2019 Apr 23;58(18):5962-5966. doi: 10.1002/anie.201900768. Epub 2019 Apr 1.

PMID:
30870573
9.

Antibiotic Korormicin A Kills Bacteria by Producing Reactive Oxygen Species.

Maynard A, Butler NL, Ito T, da Silva AJ, Murai M, Chen T, Koffas MAG, Miyoshi H, Barquera B.

J Bacteriol. 2019 May 8;201(11). pii: e00718-18. doi: 10.1128/JB.00718-18. Print 2019 Jun 1.

PMID:
30858300
10.

Focus Issue Editorial: Synthetic Biology.

Hanson AD, Hibberd JM, Koffas MAG, Kopka J, Wurtzel ET.

Plant Physiol. 2019 Mar;179(3):772-774. doi: 10.1104/pp.19.00074. No abstract available.

PMID:
30808713
11.

Rewiring the Central Metabolic Pathway for High-Yield l-Serine Production in Corynebacterium glutamicum by Using Glucose.

Zhang X, Lai L, Xu G, Zhang X, Shi J, Koffas MAG, Xu Z.

Biotechnol J. 2019 Jun;14(6):e1800497. doi: 10.1002/biot.201800497. Epub 2019 May 20.

PMID:
30791233
12.

Engineering microbial consortia by division of labor.

Roell GW, Zha J, Carr RR, Koffas MA, Fong SS, Tang YJ.

Microb Cell Fact. 2019 Feb 8;18(1):35. doi: 10.1186/s12934-019-1083-3. Review.

13.

Fine-tuning the (2S)-naringenin synthetic pathway using an iterative high-throughput balancing strategy.

Zhou S, Lyu Y, Li H, Koffas MAG, Zhou J.

Biotechnol Bioeng. 2019 Jun;116(6):1392-1404. doi: 10.1002/bit.26941. Epub 2019 Feb 11.

PMID:
30684358
14.

Magnesium starvation improves production of malonyl-CoA-derived metabolites in Escherichia coli.

Tokuyama K, Toya Y, Matsuda F, Cress BF, Koffas MAG, Shimizu H.

Metab Eng. 2019 Mar;52:215-223. doi: 10.1016/j.ymben.2018.12.002. Epub 2018 Dec 6.

PMID:
30529031
15.

Production of Deuterated Cyanidin 3-O-Glucoside from Recombinant Escherichia coli.

Gupta M, Zha J, Zhang X, Jung GY, Linhardt RJ, Koffas MAG.

ACS Omega. 2018 Sep 30;3(9):11643-11648. doi: 10.1021/acsomega.8b01134. Epub 2018 Sep 24.

16.

Engineering Bacillus megaterium Strains To Secrete Cellulases for Synergistic Cellulose Degradation in a Microbial Community.

Kalbarczyk KZ, Mazeau EJ, Rapp KM, Marchand N, Koffas MAG, Collins CH.

ACS Synth Biol. 2018 Oct 19;7(10):2413-2422. doi: 10.1021/acssynbio.8b00186. Epub 2018 Oct 3.

PMID:
30226981
17.

Editorial overview: Chemical biotechnology.

Koffas MA, Cirino PC.

Curr Opin Biotechnol. 2018 Oct;53:v-vii. doi: 10.1016/j.copbio.2018.08.010. Epub 2018 Sep 14. No abstract available.

PMID:
30224163
18.

Metabolic engineering of Corynebacterium glutamicum for anthocyanin production.

Zha J, Zang Y, Mattozzi M, Plassmeier J, Gupta M, Wu X, Clarkson S, Koffas MAG.

Microb Cell Fact. 2018 Sep 14;17(1):143. doi: 10.1186/s12934-018-0990-z.

19.

Molecular parts and genetic circuits for metabolic engineering of microorganisms.

Kim SG, Noh MH, Lim HG, Jang S, Jang S, Koffas MAG, Jung GY.

FEMS Microbiol Lett. 2018 Sep 1;365(17). doi: 10.1093/femsle/fny187. Review.

PMID:
30052915
20.

Metabolic engineering of Escherichia coli for producing adipic acid through the reverse adipate-degradation pathway.

Zhao M, Huang D, Zhang X, Koffas MAG, Zhou J, Deng Y.

Metab Eng. 2018 May;47:254-262. doi: 10.1016/j.ymben.2018.04.002. Epub 2018 Apr 3.

PMID:
29625225
21.

Production of anthocyanins in metabolically engineered microorganisms: Current status and perspectives.

Zha J, Koffas MAG.

Synth Syst Biotechnol. 2017 Oct 31;2(4):259-266. doi: 10.1016/j.synbio.2017.10.005. eCollection 2017 Dec. Review.

22.

Microbial Production of l-Serine from Renewable Feedstocks.

Zhang X, Xu G, Shi J, Koffas MAG, Xu Z.

Trends Biotechnol. 2018 Jul;36(7):700-712. doi: 10.1016/j.tibtech.2018.02.001. Epub 2018 Feb 27. Review.

PMID:
29500004
23.

The road to animal-free glycosaminoglycan production: current efforts and bottlenecks.

Badri A, Williams A, Linhardt RJ, Koffas MA.

Curr Opin Biotechnol. 2018 Oct;53:85-92. doi: 10.1016/j.copbio.2017.12.018. Epub 2018 Jan 4. Review.

PMID:
29291494
24.

Recent Advances in the Recombinant Biosynthesis of Polyphenols.

Chouhan S, Sharma K, Zha J, Guleria S, Koffas MAG.

Front Microbiol. 2017 Nov 16;8:2259. doi: 10.3389/fmicb.2017.02259. eCollection 2017. Review.

25.

Engineering Escherichia coli Co-Cultures for Production of Curcuminoids From Glucose.

Fang Z, Jones JA, Zhou J, Koffas MAG.

Biotechnol J. 2018 May;13(5):e1700576. doi: 10.1002/biot.201700576. Epub 2017 Dec 5.

PMID:
29149547
26.

Improved strategies for electrochemical 1,4-NAD(P)H2 regeneration: A new era of bioreactors for industrial biocatalysis.

Morrison CS, Armiger WB, Dodds DR, Dordick JS, Koffas MAG.

Biotechnol Adv. 2018 Jan - Feb;36(1):120-131. doi: 10.1016/j.biotechadv.2017.10.003. Epub 2017 Oct 10. Review.

PMID:
29030132
27.

Expression of chondroitin-4-O-sulfotransferase in Escherichia coli and Pichia pastoris.

He W, Zhu Y, Shirke A, Sun X, Liu J, Gross RA, Koffas MAG, Linhardt RJ, Li M.

Appl Microbiol Biotechnol. 2017 Sep;101(18):6919-6928. doi: 10.1007/s00253-017-8411-5. Epub 2017 Jul 31.

PMID:
28761999
28.

Development of Artificial Riboswitches for Monitoring of Naringenin In Vivo.

Jang S, Jang S, Xiu Y, Kang TJ, Lee SH, Koffas MAG, Jung GY.

ACS Synth Biol. 2017 Nov 17;6(11):2077-2085. doi: 10.1021/acssynbio.7b00128. Epub 2017 Aug 10.

PMID:
28749656
29.

Complete Biosynthesis of Anthocyanins Using E. coli Polycultures.

Jones JA, Vernacchio VR, Collins SM, Shirke AN, Xiu Y, Englaender JA, Cress BF, McCutcheon CC, Linhardt RJ, Gross RA, Koffas MAG.

MBio. 2017 Jun 6;8(3). pii: e00621-17. doi: 10.1128/mBio.00621-17.

30.

Naringenin-responsive riboswitch-based fluorescent biosensor module for Escherichia coli co-cultures.

Xiu Y, Jang S, Jones JA, Zill NA, Linhardt RJ, Yuan Q, Jung GY, Koffas MAG.

Biotechnol Bioeng. 2017 Oct;114(10):2235-2244. doi: 10.1002/bit.26340. Epub 2017 Jun 5.

PMID:
28543037
31.

Engineered heparins as new anticoagulant drugs.

Vaidyanathan D, Williams A, Dordick JS, Koffas MAG, Linhardt RJ.

Bioeng Transl Med. 2017 Mar;2(1):17-30. doi: 10.1002/btm2.10042. Epub 2016 Nov 21. Review.

32.

Identification of the binding sites for ubiquinone and inhibitors in the Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae by photoaffinity labeling.

Ito T, Murai M, Ninokura S, Kitazumi Y, Mezic KG, Cress BF, Koffas MAG, Morgan JE, Barquera B, Miyoshi H.

J Biol Chem. 2017 May 12;292(19):7727-7742. doi: 10.1074/jbc.M117.781393. Epub 2017 Mar 15.

33.

CRISPRi-mediated metabolic engineering of E. coli for O-methylated anthocyanin production.

Cress BF, Leitz QD, Kim DC, Amore TD, Suzuki JY, Linhardt RJ, Koffas MA.

Microb Cell Fact. 2017 Jan 17;16(1):10. doi: 10.1186/s12934-016-0623-3.

34.

Effect of Genomic Integration Location on Heterologous Protein Expression and Metabolic Engineering in E. coli.

Englaender JA, Jones JA, Cress BF, Kuhlman TE, Linhardt RJ, Koffas MAG.

ACS Synth Biol. 2017 Apr 21;6(4):710-720. doi: 10.1021/acssynbio.6b00350. Epub 2017 Jan 13.

PMID:
28055177
35.

Deciphering flux adjustments of engineered E. coli cells during fermentation with changing growth conditions.

He L, Xiu Y, Jones JA, Baidoo EEK, Keasling JD, Tang YJ, Koffas MAG.

Metab Eng. 2017 Jan;39:247-256. doi: 10.1016/j.ymben.2016.12.008. Epub 2016 Dec 23.

PMID:
28017690
36.

Draft Genome Sequence of Bacillus subtilis Ia1a, a New Strain for Poly-γ-Glutamic Acid and Exopolysaccharide Production.

Ibrahim MH, Cress BF, Linhardt RJ, Koffas MA, Gross RA.

Genome Announc. 2016 Dec 15;4(6). pii: e01361-16. doi: 10.1128/genomeA.01361-16.

37.

Expression and secretion of glycosylated heparin biosynthetic enzymes using Komagataella pastoris.

Englaender JA, Zhu Y, Shirke AN, Lin L, Liu X, Zhang F, Gross RA, Koffas MA, Linhardt RJ.

Appl Microbiol Biotechnol. 2017 Apr;101(7):2843-2851. doi: 10.1007/s00253-016-8047-x. Epub 2016 Dec 14.

PMID:
27975137
38.

Engineering the biological conversion of methanol to specialty chemicals in Escherichia coli.

Whitaker WB, Jones JA, Bennett RK, Gonzalez JE, Vernacchio VR, Collins SM, Palmer MA, Schmidt S, Antoniewicz MR, Koffas MA, Papoutsakis ET.

Metab Eng. 2017 Jan;39:49-59. doi: 10.1016/j.ymben.2016.10.015. Epub 2016 Nov 1.

PMID:
27815193
39.

Comparative thermal inactivation analysis of Aspergillus oryzae and Thiellavia terrestris cutinase: Role of glycosylation.

Shirke AN, Su A, Jones JA, Butterfoss GL, Koffas MA, Kim JR, Gross RA.

Biotechnol Bioeng. 2017 Jan;114(1):63-73. doi: 10.1002/bit.26052. Epub 2016 Sep 21.

PMID:
27425027
40.

Optimizing Metabolic Pathways for the Improved Production of Natural Products.

Jones JA, Koffas MA.

Methods Enzymol. 2016;575:179-93. doi: 10.1016/bs.mie.2016.02.010. Epub 2016 Mar 10.

PMID:
27417929
41.

Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents.

Zhang X, Khalidi O, Kim SY, Wang R, Schultz V, Cress BF, Gross RA, Koffas MAG, Linhardt RJ.

Bioorg Med Chem Lett. 2016 Jul 1;26(13):3089-3092. doi: 10.1016/j.bmcl.2016.05.003. Epub 2016 May 4.

PMID:
27210435
42.

Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli.

Cress BF, Jones JA, Kim DC, Leitz QD, Englaender JA, Collins SM, Linhardt RJ, Koffas MA.

Nucleic Acids Res. 2016 May 19;44(9):4472-85. doi: 10.1093/nar/gkw231. Epub 2016 Apr 13.

43.

Metabolic Burden: Cornerstones in Synthetic Biology and Metabolic Engineering Applications.

Wu G, Yan Q, Jones JA, Tang YJ, Fong SS, Koffas MAG.

Trends Biotechnol. 2016 Aug;34(8):652-664. doi: 10.1016/j.tibtech.2016.02.010. Epub 2016 Mar 18. Review.

PMID:
26996613
44.

Microbial production of natural and non-natural flavonoids: Pathway engineering, directed evolution and systems/synthetic biology.

Pandey RP, Parajuli P, Koffas MAG, Sohng JK.

Biotechnol Adv. 2016 Sep-Oct;34(5):634-662. doi: 10.1016/j.biotechadv.2016.02.012. Epub 2016 Mar 3. Review.

PMID:
26946281
45.

Experimental and computational optimization of an Escherichia coli co-culture for the efficient production of flavonoids.

Jones JA, Vernacchio VR, Sinkoe AL, Collins SM, Ibrahim MHA, Lachance DM, Hahn J, Koffas MAG.

Metab Eng. 2016 May;35:55-63. doi: 10.1016/j.ymben.2016.01.006. Epub 2016 Feb 6.

PMID:
26860871
46.

Microbial production of value-added nutraceuticals.

Wang J, Guleria S, Koffas MA, Yan Y.

Curr Opin Biotechnol. 2016 Feb;37:97-104. doi: 10.1016/j.copbio.2015.11.003. Epub 2015 Dec 21. Review.

PMID:
26716360
47.

Optimization of naringenin and p-coumaric acid hydroxylation using the native E. coli hydroxylase complex, HpaBC.

Jones JA, Collins SM, Vernacchio VR, Lachance DM, Koffas MA.

Biotechnol Prog. 2016 Jan-Feb;32(1):21-5. doi: 10.1002/btpr.2185. Epub 2015 Nov 11.

PMID:
26488898
48.

Sensitive cells: enabling tools for static and dynamic control of microbial metabolic pathways.

Cress BF, Trantas EA, Ververidis F, Linhardt RJ, Koffas MA.

Curr Opin Biotechnol. 2015 Dec;36:205-14. doi: 10.1016/j.copbio.2015.09.007. Epub 2015 Nov 2. Review.

PMID:
26453934
49.

Development of a Recombinant Escherichia coli Strain for Overproduction of the Plant Pigment Anthocyanin.

Lim CG, Wong L, Bhan N, Dvora H, Xu P, Venkiteswaran S, Koffas MA.

Appl Environ Microbiol. 2015 Sep;81(18):6276-84. doi: 10.1128/AEM.01448-15. Epub 2015 Jul 6.

50.

Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol.

Mora-Pale M, Bhan N, Masuko S, James P, Wood J, McCallum S, Linhardt RJ, Dordick JS, Koffas MA.

Biotechnol Bioeng. 2015 Dec;112(12):2417-28. doi: 10.1002/bit.25686. Epub 2015 Aug 26.

PMID:
26109045

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