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Items: 1 to 50 of 158

1.

The Human Vaccines Project: Towards a comprehensive understanding of the human immune response to immunization.

Wooden SL, Koff WC.

Hum Vaccin Immunother. 2018;14(9):2214-2216. doi: 10.1080/21645515.2018.1476813. Epub 2018 Jun 28. Review.

2.

A bioinformatics roadmap for the human vaccines project.

Scheuermann RH, Sinkovits RS, Schenkelberg T, Koff WC.

Expert Rev Vaccines. 2017 Jun;16(6):535-544. doi: 10.1080/14760584.2017.1322752. Epub 2017 May 9. Review.

PMID:
28434256
3.

Assessment of satisfaction and Quality of Life using self -reported questionnaires after urethroplasty: a prospective analysis.

Lucas ET, Koff WJ, Rosito TE, Berger M, Bortolini T, Neto BS.

Int Braz J Urol. 2017 Mar-Apr;43(2):304-310. doi: 10.1590/S1677-5538.IBJU.2016.0207.

5.

Novel approaches in preclinical HIV vaccine research.

Safrit JT, Koff WC.

Curr Opin HIV AIDS. 2016 Nov;11(6):601-606. Review.

PMID:
27636502
6.

Association of mutations in V3/C3 domain with enhanced sensitivity of HIV-1 clade C primary envelopes to autologous broadly neutralizing plasma antibodies.

Deshpande S, Patil S, Kumar R, Shrivastava T, Srikrishnan AK, Murugavel KG, Koff WC, Chakrabarti BK, Bhattacharya J.

Retrovirology. 2016 Jun 15;13(1):41. doi: 10.1186/s12977-016-0273-x.

7.

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.

Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O'Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR.

Science. 2016 May 13;352(6287):828-33. doi: 10.1126/science.aae0474.

8.

A shot at AIDS.

Koff WC.

Curr Opin Biotechnol. 2016 Dec;42:147-151. doi: 10.1016/j.copbio.2016.03.007. Epub 2016 May 3. Review.

PMID:
27153215
9.

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.

Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, Kwon YD, Pancera M, Taft J, Yang Y, Zhang B, Shivatare SS, Shivatare VS, Lee CC, Wu CY, Bewley CA, Burton DR, Koff WC, Connors M, Crispin M, Baxa U, Korber BT, Wong CH, Mascola JR, Kwong PD.

Cell. 2016 May 5;165(4):813-26. doi: 10.1016/j.cell.2016.04.010. Epub 2016 Apr 21.

10.

The Human Vaccines Project: A roadmap for cancer vaccine development.

Romero P, Banchereau J, Bhardwaj N, Cockett M, Disis ML, Dranoff G, Gilboa E, Hammond SA, Hershberg R, Korman AJ, Kvistborg P, Melief C, Mellman I, Palucka AK, Redchenko I, Robins H, Sallusto F, Schenkelberg T, Schoenberger S, Sosman J, Türeci Ö, Van den Eynde B, Koff W, Coukos G.

Sci Transl Med. 2016 Apr 13;8(334):334ps9. doi: 10.1126/scitranslmed.aaf0685. Review.

PMID:
27075624
11.

Decoding the human immune system to transform the future of global disease prevention and control.

Koff WC, Schenkelberg T.

Expert Rev Vaccines. 2016 Oct;15(10):1235-6. doi: 10.1586/14760584.2016.1170600. Epub 2016 May 25. No abstract available.

PMID:
27010379
12.

Status of vaccine research and development of vaccines for HIV-1.

Safrit JT, Fast PE, Gieber L, Kuipers H, Dean HJ, Koff WC.

Vaccine. 2016 Jun 3;34(26):2921-2925. doi: 10.1016/j.vaccine.2016.02.074. Epub 2016 Mar 15.

13.

Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C-Infected Elite Neutralizer Mediate Autologous Virus Escape through Mutations in the V1 Loop.

Patil S, Kumar R, Deshpande S, Samal S, Shrivastava T, Boliar S, Bansal M, Chaudhary NK, Srikrishnan AK, Murugavel KG, Solomon S, Simek M, Koff WC, Goyal R, Chakrabarti BK, Bhattacharya J.

J Virol. 2016 Jan 13;90(7):3446-57. doi: 10.1128/JVI.03090-15.

14.

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.

de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW.

Cell. 2015 Dec 17;163(7):1702-15. doi: 10.1016/j.cell.2015.11.056.

15.

Deciphering the human antigenome.

Sette A, Schenkelberg TR, Koff WC.

Expert Rev Vaccines. 2016;15(2):167-71. doi: 10.1586/14760584.2016.1112743. Epub 2015 Dec 2.

PMID:
26629807
16.

Deciphering the human immunome.

Crowe JE Jr, Koff WC.

Expert Rev Vaccines. 2015;14(11):1421-5. doi: 10.1586/14760584.2015.1082427. Epub 2015 Aug 24.

PMID:
26485213
17.

Analysis of the effects of topical renal hypothermia on lung tissue after kidney ischemia and reperfusion in rats.

Fiorentini MR, Santos EB, Longo L, Kliemann LM, Koff WJ, Corso CO.

Acta Cir Bras. 2015 Jul;30(7):445-51. doi: 10.1590/S0102-865020150070000001.

18.

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.

Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, Debnath G, Moldt B, van Breemen MJ, Isik G, Medina-Ramírez M, Back JW, Koff WC, Julien JP, Rakasz EG, Seaman MS, Guttman M, Lee KK, Klasse PJ, LaBranche C, Schief WR, Wilson IA, Overbaugh J, Burton DR, Ward AB, Montefiori DC, Dean H, Moore JP.

Science. 2015 Jul 10;349(6244):aac4223. doi: 10.1126/science.aac4223. Epub 2015 Jun 18.

19.

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.

Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, O'Dell S, Schmidt SD, Tran L, Yang Z, Druz A, Luongo TS, Moquin S, Srivatsan S, Yang Y, Zhang B, Zheng A, Pancera M, Kirys T, Georgiev IS, Gindin T, Peng HP, Yang AS; NISC Comparative Sequencing Program, Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF, Casazza JP, Connors M, Corti D, Lanzavecchia A, Sattentau QJ, Weiss RA, West AP Jr, Bjorkman PJ, Scheid JF, Nussenzweig MC, Shapiro L, Mascola JR, Kwong PD.

Cell. 2015 Jun 4;161(6):1280-92. doi: 10.1016/j.cell.2015.05.007. Epub 2015 May 21.

20.

Imaging of the adrenal gland lesions.

Herr K, Muglia VF, Koff WJ, Westphalen AC.

Radiol Bras. 2014 Jul-Aug;47(4):228-39. doi: 10.1590/0100-3984.2013.1762. Review.

21.

Building the Human Vaccines Project: strategic management recommendations and summary report of the 15-16 July 2014 business workshop.

Schenkelberg T, Kieny MP, Bianco AE, Koff WC.

Expert Rev Vaccines. 2015 May;14(5):629-36. doi: 10.1586/14760584.2015.1013466. Epub 2015 Feb 11. Review.

PMID:
25673514
22.

Wayne Koff.

Koff W, Mullard A.

Nat Rev Drug Discov. 2015 Jan;14(1):10. doi: 10.1038/nrd4528. No abstract available.

PMID:
25549583
23.

Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding.

He L, Sok D, Azadnia P, Hsueh J, Landais E, Simek M, Koff WC, Poignard P, Burton DR, Zhu J.

Sci Rep. 2014 Oct 27;4:6778. doi: 10.1038/srep06778.

24.

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions.

Munro JB, Gorman J, Ma X, Zhou Z, Arthos J, Burton DR, Koff WC, Courter JR, Smith AB 3rd, Kwong PD, Blanchard SC, Mothes W.

Science. 2014 Nov 7;346(6210):759-63. doi: 10.1126/science.1254426. Epub 2014 Oct 8.

25.

Transplanting supersites of HIV-1 vulnerability.

Zhou T, Zhu J, Yang Y, Gorman J, Ofek G, Srivatsan S, Druz A, Lees CR, Lu G, Soto C, Stuckey J, Burton DR, Koff WC, Connors M, Kwong PD.

PLoS One. 2014 Jul 3;9(7):e99881. doi: 10.1371/journal.pone.0099881. eCollection 2014. Erratum in: PLoS One. 2014;9(8); e105659. doi: 10.1371/journal.pone.0105659. Kwon, Peter D [corrected to Kwong, Peter D].

26.

Toward a human vaccines project.

Koff WC, Gust ID, Plotkin SA.

Nat Immunol. 2014 Jul;15(7):589-92. doi: 10.1038/ni.2871. No abstract available.

PMID:
24940943
27.

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.

Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang CH, Mcbride R, von Bredow B, Shivatare SS, Wu CY, Chan-Hui PY, Liu Y, Feizi T, Zwick MB, Koff WC, Seaman MS, Swiderek K, Moore JP, Evans D, Paulson JC, Wong CH, Ward AB, Wilson IA, Sanders RW, Poignard P, Burton DR.

Immunity. 2014 May 15;40(5):657-68. doi: 10.1016/j.immuni.2014.04.009. Epub 2014 Apr 24.

28.
29.

Vaccines that stimulate T cell immunity to HIV-1: the next step.

McMichael AJ, Koff WC.

Nat Immunol. 2014 Apr;15(4):319-22. doi: 10.1038/ni.2844.

30.

BDNF: a biomarker for social vulnerability in individuals diagnosed with gender dysphoria.

Costa AB, Fontanari AM, Andreazza T, Salvador J, Koff WJ, Aguiar B, Ferrari P, Massuda R, Pedrini M, Silveira E, Belmonte-de-Abreu PS, Gama CS, Kauer-Sant'Anna M, Kapczinski F, Lobato MI.

J Psychiatr Res. 2014 Mar;50:16-7. doi: 10.1016/j.jpsychires.2013.11.009. Epub 2013 Dec 1. No abstract available.

PMID:
24332481
31.

Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies.

Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Kwon YD, Longo NS, Louder MK, Luongo T, McKee K, Schramm CA, Skinner J, Yang Y, Yang Z, Zhang Z, Zheng A, Bonsignori M, Haynes BF, Scheid JF, Nussenzweig MC, Simek M, Burton DR, Koff WC; NISC Comparative Sequencing Program, Mullikin JC, Connors M, Shapiro L, Nabel GJ, Mascola JR, Kwong PD.

Immunity. 2013 Aug 22;39(2):245-58. doi: 10.1016/j.immuni.2013.04.012. Epub 2013 Aug 1.

32.

Oxidative stress evaluation of ischemia and reperfusion in kidneys under various degrees of hypothermia in rats.

Santos EB, Koff WJ, Grezzana Filho Tde J, De Rossi SD, Treis L, Bona SR, Pêgas KL, Katz B, Meyer FS, Marroni NA, Corso CO.

Acta Cir Bras. 2013 Aug;28(8):568-73.

33.

Discordant transsexualism in male monozygotic twins: neuroanatomical and psychological differences.

Andreazza TS, Costa AB, Massuda R, Salvador J, Silveira EM, Piccon F, Carvalho R, Fontanari AM, Koff W, Belmonte-de-Abreu P, Lobato MI.

Arch Sex Behav. 2014 Feb;43(2):399-405. doi: 10.1007/s10508-013-0151-8. Epub 2013 Jul 12.

PMID:
23857518
34.

Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.

Amin MN, McLellan JS, Huang W, Orwenyo J, Burton DR, Koff WC, Kwong PD, Wang LX.

Nat Chem Biol. 2013 Aug;9(8):521-6. doi: 10.1038/nchembio.1288. Epub 2013 Jun 30.

35.

Accelerating next-generation vaccine development for global disease prevention.

Koff WC, Burton DR, Johnson PR, Walker BD, King CR, Nabel GJ, Ahmed R, Bhan MK, Plotkin SA.

Science. 2013 May 31;340(6136):1232910. doi: 10.1126/science.1232910. Review.

36.

Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.

Pancera M, Shahzad-Ul-Hussan S, Doria-Rose NA, McLellan JS, Bailer RT, Dai K, Loesgen S, Louder MK, Staupe RP, Yang Y, Zhang B, Parks R, Eudailey J, Lloyd KE, Blinn J, Alam SM, Haynes BF, Amin MN, Wang LX, Burton DR, Koff WC, Nabel GJ, Mascola JR, Bewley CA, Kwong PD.

Nat Struct Mol Biol. 2013 Jul;20(7):804-13. doi: 10.1038/nsmb.2600. Epub 2013 May 26.

37.

Serum concentrations of brain-derived neurotrophic factor in patients with gender identity disorder.

Fontanari AM, Andreazza T, Costa ÂB, Salvador J, Koff WJ, Aguiar B, Ferrari P, Massuda R, Pedrini M, Silveira E, Belmonte-de-Abreu PS, Gama CS, Kauer-Sant'Anna M, Kapczinski F, Lobato MI.

J Psychiatr Res. 2013 Oct;47(10):1546-8. doi: 10.1016/j.jpsychires.2013.04.012. Epub 2013 May 20.

PMID:
23702250
38.

Accelerating the development of a safe and effective HIV vaccine: HIV vaccine case study for the Decade of Vaccines.

Koff WC, Russell ND, Walport M, Feinberg MB, Shiver JW, Karim SA, Walker BD, McGlynn MG, Nweneka CV, Nabel GJ.

Vaccine. 2013 Apr 18;31 Suppl 2:B204-8. doi: 10.1016/j.vaccine.2012.10.115. Review.

PMID:
23598483
39.

Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains.

Zhu J, Ofek G, Yang Y, Zhang B, Louder MK, Lu G, McKee K, Pancera M, Skinner J, Zhang Z, Parks R, Eudailey J, Lloyd KE, Blinn J, Alam SM, Haynes BF, Simek M, Burton DR, Koff WC; NISC Comparative Sequencing Program, Mullikin JC, Mascola JR, Shapiro L, Kwong PD.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6470-5. doi: 10.1073/pnas.1219320110. Epub 2013 Mar 27.

40.

Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes.

Hoffenberg S, Powell R, Carpov A, Wagner D, Wilson A, Kosakovsky Pond S, Lindsay R, Arendt H, Destefano J, Phogat S, Poignard P, Fling SP, Simek M, Labranche C, Montefiori D, Wrin T, Phung P, Burton D, Koff W, King CR, Parks CL, Caulfield MJ.

J Virol. 2013 May;87(10):5372-83. doi: 10.1128/JVI.02827-12. Epub 2013 Mar 6.

41.

N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function.

Pancera M, Yang Y, Louder MK, Gorman J, Lu G, McLellan JS, Stuckey J, Zhu J, Burton DR, Koff WC, Mascola JR, Kwong PD.

PLoS One. 2013;8(2):e55701. doi: 10.1371/journal.pone.0055701. Epub 2013 Feb 19.

42.

Androgen receptor GGC polymorphism and testosterone levels associated with high risk of prostate cancer and benign prostatic hyperplasia.

Biolchi V, Silva Neto B, Pianta DB, Koff WJ, Berger M, Brum IS.

Mol Biol Rep. 2013 Mar;40(3):2749-56. doi: 10.1007/s11033-012-2293-5. Epub 2012 Nov 27.

PMID:
23184046
43.

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics.

Zhu J, O'Dell S, Ofek G, Pancera M, Wu X, Zhang B, Zhang Z; NISC Comparative Sequencing Program, Mullikin JC, Simek M, Burton DR, Koff WC, Shapiro L, Mascola JR, Kwong PD.

Front Microbiol. 2012 Sep 11;3:315. eCollection 2012.

44.

Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection.

Champiat S, Raposo RA, Maness NJ, Lehman JL, Purtell SE, Hasenkrug AM, Miller JC, Dean H, Koff WC, Hong MA, Martin JN, Deeks SG, Spotts GE, Pilcher CD, Hecht FM, Kallas EG, Garrison KE, Nixon DF.

PLoS One. 2012;7(6):e39311. doi: 10.1371/journal.pone.0039311. Epub 2012 Jun 29.

45.

Androgen receptor CAG polymorphism and the risk of benign prostatic hyperplasia in a Brazilian population.

Biolchi V, Silva Neto B, Koff W, Brum IS.

Int Braz J Urol. 2012 May-Jun;38(3):373-9.

46.

Minimum 2-year follow up of sex reassignment surgery in Brazilian male-to-female transsexuals.

Salvador J, Massuda R, Andreazza T, Koff WJ, Silveira E, Kreische F, de Souza L, de Oliveira MH, Rosito T, Fernandes BS, Lobato MI.

Psychiatry Clin Neurosci. 2012 Jun;66(4):371-2. doi: 10.1111/j.1440-1819.2012.02342.x. No abstract available.

47.

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies.

Doria-Rose NA, Georgiev I, O'Dell S, Chuang GY, Staupe RP, McLellan JS, Gorman J, Pancera M, Bonsignori M, Haynes BF, Burton DR, Koff WC, Kwong PD, Mascola JR.

J Virol. 2012 Aug;86(15):8319-23. doi: 10.1128/JVI.00696-12. Epub 2012 May 23.

48.

A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challenge.

Reynolds MR, Weiler AM, Piaskowski SM, Piatak M Jr, Robertson HT, Allison DB, Bett AJ, Casimiro DR, Shiver JW, Wilson NA, Lifson JD, Koff WC, Watkins DI.

Vaccine. 2012 Jun 22;30(30):4465-75. doi: 10.1016/j.vaccine.2012.04.082. Epub 2012 May 6.

49.

Analysis of KIR gene frequencies and HLA class I genotypes in prostate cancer and control group.

Portela P, Jobim LF, Salim PH, Koff WJ, Wilson TJ, Jobim MR, Schwartsmann G, Roesler R, Jobim M.

Int J Immunogenet. 2012 Oct;39(5):423-8. doi: 10.1111/j.1744-313X.2012.01115.x. Epub 2012 Apr 10.

PMID:
22487023
50.

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.

McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, Zhou T, Zhu J, Boyington JC, Chuang GY, Diwanji D, Georgiev I, Kwon YD, Lee D, Louder MK, Moquin S, Schmidt SD, Yang ZY, Bonsignori M, Crump JA, Kapiga SH, Sam NE, Haynes BF, Burton DR, Koff WC, Walker LM, Phogat S, Wyatt R, Orwenyo J, Wang LX, Arthos J, Bewley CA, Mascola JR, Nabel GJ, Schief WR, Ward AB, Wilson IA, Kwong PD.

Nature. 2011 Nov 23;480(7377):336-43. doi: 10.1038/nature10696.

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