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Items: 1 to 50 of 69

1.

Variation in DNA Methylation of Human Blood over a 1-Year Period using the Illumina MethylationEPIC array.

Zaimi I, Pei D, Koestler DC, Marsit CJ, De Vivo I, Tworoger SS, Shields AE, Kelsey KT, Michaud DS.

Epigenetics. 2018 Sep 29. doi: 10.1080/15592294.2018.1530008. [Epub ahead of print]

PMID:
30270718
2.

Methylation-derived Neutrophil-to-Lymphocyte Ratio and Lung Cancer Risk in Heavy Smokers.

Grieshober L, Graw S, Barnett MJ, Thornquist MD, Goodman GE, Chen C, Koestler DC, Marsit CJ, Doherty JA.

Cancer Prev Res (Phila). 2018 Sep 25. doi: 10.1158/1940-6207.CAPR-18-0111. [Epub ahead of print]

PMID:
30254071
3.

DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival.

Ambatipudi S, Langdon R, Richmond RC, Suderman M, Koestler DC, Kelsey KT, Kazmi N, Penfold C, Ho KM, McArdle W, Ring SM, Pring M, Waterboer T, Pawlita M, Gaunt TR, Davey Smith G, Thomas S, Ness AR, Relton CL.

Oral Oncol. 2018 Oct;85:87-94. doi: 10.1016/j.oraloncology.2018.08.021. Epub 2018 Sep 5.

PMID:
30220325
4.

Tracing human stem cell lineage during development using DNA methylation.

Salas LA, Wiencke JK, Koestler DC, Zhang Z, Christensen BC, Kelsey KT.

Genome Res. 2018 Sep;28(9):1285-1295. doi: 10.1101/gr.233213.117. Epub 2018 Aug 2.

5.

Licofelone Enhances the Efficacy of Paclitaxel in Ovarian Cancer by Reversing Drug Resistance and Tumor Stem-like Properties.

Hirst J, Pathak HB, Hyter S, Pessetto ZY, Ly T, Graw S, Koestler DC, Krieg AJ, Roby KF, Godwin AK.

Cancer Res. 2018 Aug 1;78(15):4370-4385. doi: 10.1158/0008-5472.CAN-17-3993. Epub 2018 Jun 11.

PMID:
29891506
6.

An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray.

Salas LA, Koestler DC, Butler RA, Hansen HM, Wiencke JK, Kelsey KT, Christensen BC.

Genome Biol. 2018 May 29;19(1):64. doi: 10.1186/s13059-018-1448-7.

7.

Association of Neutrophil-to-Lymphocyte Ratio With Mortality and Cardiovascular Disease in the Jackson Heart Study and Modification by the Duffy Antigen Variant.

Kim S, Eliot M, Koestler DC, Wu WC, Kelsey KT.

JAMA Cardiol. 2018 Jun 1;3(6):455-462. doi: 10.1001/jamacardio.2018.1042.

PMID:
29801037
8.

Developing a genetic signature to predict drug response in ovarian cancer.

Hyter S, Hirst J, Pathak H, Pessetto ZY, Koestler DC, Raghavan R, Pei D, Godwin AK.

Oncotarget. 2017 Dec 26;9(19):14828-14848. doi: 10.18632/oncotarget.23663. eCollection 2018 Mar 13.

9.

Mediation analysis of alcohol consumption, DNA methylation, and epithelial ovarian cancer.

Wu D, Yang H, Winham SJ, Natanzon Y, Koestler DC, Luo T, Fridley BL, Goode EL, Zhang Y, Cui Y.

J Hum Genet. 2018 Mar;63(3):339-348. doi: 10.1038/s10038-017-0385-8. Epub 2018 Jan 10.

10.

Mitochondrial Haplotype Alters Mammary Cancer Tumorigenicity and Metastasis in an Oncogenic Driver-Dependent Manner.

Brinker AE, Vivian CJ, Koestler DC, Tsue TT, Jensen RA, Welch DR.

Cancer Res. 2017 Dec 15;77(24):6941-6949. doi: 10.1158/0008-5472.CAN-17-2194. Epub 2017 Oct 25.

PMID:
29070615
11.

Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism.

Tan EP, McGreal SR, Graw S, Tessman R, Koppel SJ, Dhakal P, Zhang Z, Machacek M, Zachara NE, Koestler DC, Peterson KR, Thyfault JP, Swerdlow RH, Krishnamurthy P, DiTacchio L, Apte U, Slawson C.

J Biol Chem. 2017 Sep 8;292(36):14940-14962. doi: 10.1074/jbc.M117.797944. Epub 2017 Jul 24.

12.

Mitochondrial Genomic Backgrounds Affect Nuclear DNA Methylation and Gene Expression.

Vivian CJ, Brinker AE, Graw S, Koestler DC, Legendre C, Gooden GC, Salhia B, Welch DR.

Cancer Res. 2017 Nov 15;77(22):6202-6214. doi: 10.1158/0008-5472.CAN-17-1473. Epub 2017 Jun 29.

PMID:
28663334
13.

Maternal serum PFOA concentration and DNA methylation in cord blood: A pilot study.

Kingsley SL, Kelsey KT, Butler R, Chen A, Eliot MN, Romano ME, Houseman A, Koestler DC, Lanphear BP, Yolton K, Braun JM.

Environ Res. 2017 Oct;158:174-178. doi: 10.1016/j.envres.2017.06.013. Epub 2017 Jun 20.

14.

The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression.

Winterbottom EF, Koestler DC, Fei DL, Wika E, Capobianco AJ, Marsit CJ, Karagas MR, Robbins DJ.

Environ Health. 2017 Jun 14;16(1):59. doi: 10.1186/s12940-017-0267-8.

15.

Integrative epigenetic and genetic pan-cancer somatic alteration portraits.

Salas LA, Johnson KC, Koestler DC, O'Sullivan DE, Christensen BC.

Epigenetics. 2017 Jul 3;12(7):561-574. doi: 10.1080/15592294.2017.1319043. Epub 2017 Apr 20.

16.

Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses.

Zheng SC, Beck S, Jaffe AE, Koestler DC, Hansen KD, Houseman AE, Irizarry RA, Teschendorff AE.

Nat Methods. 2017 Feb 28;14(3):216-217. doi: 10.1038/nmeth.4187. No abstract available.

PMID:
28245219
17.

Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival.

Wiencke JK, Koestler DC, Salas LA, Wiemels JL, Roy RP, Hansen HM, Rice T, McCoy LS, Bracci PM, Molinaro AM, Kelsey KT, Wrensch MR, Christensen BC.

Clin Epigenetics. 2017 Feb 2;9:10. doi: 10.1186/s13148-017-0316-8. eCollection 2017.

18.

DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio: An Epigenetic Tool to Explore Cancer Inflammation and Outcomes.

Koestler DC, Usset J, Christensen BC, Marsit CJ, Karagas MR, Kelsey KT, Wiencke JK.

Cancer Epidemiol Biomarkers Prev. 2017 Mar;26(3):328-338. doi: 10.1158/1055-9965.EPI-16-0461. Epub 2016 Dec 13.

19.

Enlarged leukocyte referent libraries can explain additional variance in blood-based epigenome-wide association studies.

Kim S, Eliot M, Koestler DC, Houseman EA, Wetmur JG, Wiencke JK, Kelsey KT.

Epigenomics. 2016 Sep;8(9):1185-92. doi: 10.2217/epi-2016-0037. Epub 2016 Aug 16.

20.

Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma.

O'Sullivan DE, Johnson KC, Skinner L, Koestler DC, Christensen BC.

Epigenetics. 2016 May 3;11(5):344-53. doi: 10.1080/15592294.2016.1168673. Epub 2016 Apr 12.

21.

Prenatal Programming of Infant Neurobehaviour in a Healthy Population.

Appleton AA, Murphy MA, Koestler DC, Lesseur C, Paquette AG, Padbury JF, Lester BM, Marsit CJ.

Paediatr Perinat Epidemiol. 2016 Jul;30(4):367-75. doi: 10.1111/ppe.12294. Epub 2016 Mar 23.

22.

Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL).

Koestler DC, Jones MJ, Usset J, Christensen BC, Butler RA, Kobor MS, Wiencke JK, Kelsey KT.

BMC Bioinformatics. 2016 Mar 8;17:120. doi: 10.1186/s12859-016-0943-7.

23.

CpG island methylation profile in non-invasive oral rinse samples is predictive of oral and pharyngeal carcinoma.

Langevin SM, Eliot M, Butler RA, Cheong A, Zhang X, McClean MD, Koestler DC, Kelsey KT.

Clin Epigenetics. 2015 Dec 3;7:125. doi: 10.1186/s13148-015-0160-7. eCollection 2015.

24.

GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth.

Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ.

EBioMedicine. 2015 May 1;2(6):536-43. doi: 10.1016/j.ebiom.2015.04.019. eCollection 2015 Jun.

25.

DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer.

Johnson KC, Koestler DC, Fleischer T, Chen P, Jenson EG, Marotti JD, Onega T, Kristensen VN, Christensen BC.

Clin Epigenetics. 2015 Jul 25;7:75. doi: 10.1186/s13148-015-0094-0. eCollection 2015.

26.

DNA methylation changes in the placenta are associated with fetal manganese exposure.

Maccani JZ, Koestler DC, Houseman EA, Armstrong DA, Marsit CJ, Kelsey KT.

Reprod Toxicol. 2015 Nov;57:43-9. doi: 10.1016/j.reprotox.2015.05.002. Epub 2015 May 15.

27.

Differential DNA methylation in umbilical cord blood of infants exposed to mercury and arsenic in utero.

Cardenas A, Koestler DC, Houseman EA, Jackson BP, Kile ML, Karagas MR, Marsit CJ.

Epigenetics. 2015;10(6):508-15. doi: 10.1080/15592294.2015.1046026. Epub 2015 Apr 29.

28.

Genome wide DNA methylation profiles provide clues to the origin and pathogenesis of germ cell tumors.

Rijlaarsdam MA, Tax DM, Gillis AJ, Dorssers LC, Koestler DC, de Ridder J, Looijenga LH.

PLoS One. 2015 Apr 10;10(4):e0122146. doi: 10.1371/journal.pone.0122146. eCollection 2015. Erratum in: PLoS One. 2015;10(7):e0132981.

29.

Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis.

Hoen AG, Li J, Moulton LA, O'Toole GA, Housman ML, Koestler DC, Guill MF, Moore JH, Hibberd PL, Morrison HG, Sogin ML, Karagas MR, Madan JC.

J Pediatr. 2015 Jul;167(1):138-47.e1-3. doi: 10.1016/j.jpeds.2015.02.049. Epub 2015 Mar 26.

30.

Placental DNA Methylation Related to Both Infant Toenail Mercury and Adverse Neurobehavioral Outcomes.

Maccani JZ, Koestler DC, Lester B, Houseman EA, Armstrong DA, Kelsey KT, Marsit CJ.

Environ Health Perspect. 2015 Jul;123(7):723-9. doi: 10.1289/ehp.1408561. Epub 2015 Mar 6.

31.

The era of integrative genomics: more data or better methods?

Koestler DC, Jones MJ, Kobor MS.

Epigenomics. 2014;6(5):463-7. doi: 10.2217/epi.14.44. No abstract available. Erratum in: Epigenomics. 2014;6(6):690. Jones, Meaghan [corrected to Jones, Meaghan J]; Kobor, Michael [corrected to Kobor, Michael S].

32.

Fetal exposures and perinatal influences on the stool microbiota of premature infants.

Chernikova DA, Koestler DC, Hoen AG, Housman ML, Hibberd PL, Moore JH, Morrison HG, Sogin ML, Zain-Ul-Abideen M, Madan JC.

J Matern Fetal Neonatal Med. 2016;29(1):99-105. doi: 10.3109/14767058.2014.987748. Epub 2015 Sep 4.

33.

A recursively partitioned mixture model for clustering time-course gene expression data.

Koestler DC, Marsit CJ, Christensen BC, Kelsey KT, Houseman EA.

Transl Cancer Res. 2014;3(3):217-232.

34.

Integrative clustering methods for high-dimensional molecular data.

Chalise P, Koestler DC, Bimali M, Yu Q, Fridley BL.

Transl Cancer Res. 2014 Jun 1;3(3):202-216.

35.

Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort.

Paquette AG, Lester BM, Koestler DC, Lesseur C, Armstrong DA, Marsit CJ.

PLoS One. 2014 Aug 12;9(8):e104913. doi: 10.1371/journal.pone.0104913. eCollection 2014.

36.

Methylation of leukocyte DNA and ovarian cancer: relationships with disease status and outcome.

Fridley BL, Armasu SM, Cicek MS, Larson MC, Wang C, Winham SJ, Kalli KR, Koestler DC, Rider DN, Shridhar V, Olson JE, Cunningham JM, Goode EL.

BMC Med Genomics. 2014 Apr 28;7:21. doi: 10.1186/1755-8794-7-21.

37.

Individualizing care for ovarian cancer patients using big data.

Fridley BL, Koestler DC, Godwin AK.

J Natl Cancer Inst. 2014 Apr 3;106(5). pii: dju080. doi: 10.1093/jnci/dju080. No abstract available. Erratum in: J Natl Cancer Inst. 2014 Aug;106(8):dju234 doi:10.1093/jnci/dju234. Devin C. Koeslter [corrected to Devin C. Koestler].

PMID:
24700802
38.

Leukocyte-adjusted epigenome-wide association studies of blood from solid tumor patients.

Langevin SM, Houseman EA, Accomando WP, Koestler DC, Christensen BC, Nelson HH, Karagas MR, Marsit CJ, Wiencke JK, Kelsey KT.

Epigenetics. 2014 Jun;9(6):884-95. doi: 10.4161/epi.28575. Epub 2014 Mar 26.

39.

Sex-specific associations between placental leptin promoter DNA methylation and infant neurobehavior.

Lesseur C, Armstrong DA, Murphy MA, Appleton AA, Koestler DC, Paquette AG, Lester BM, Marsit CJ.

Psychoneuroendocrinology. 2014 Feb;40:1-9. doi: 10.1016/j.psyneuen.2013.10.012. Epub 2013 Oct 30.

40.

Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer.

Koestler DC, Chalise P, Cicek MS, Cunningham JM, Armasu S, Larson MC, Chien J, Block M, Kalli KR, Sellers TA, Fridley BL, Goode EL.

BMC Med Genomics. 2014 Jan 30;7:8. doi: 10.1186/1755-8794-7-8.

41.

Placental DNA methylation alterations associated with maternal tobacco smoking at the RUNX3 gene are also associated with gestational age.

Maccani JZ, Koestler DC, Houseman EA, Marsit CJ, Kelsey KT.

Epigenomics. 2013 Dec;5(6):619-30. doi: 10.2217/epi.13.63.

42.

Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation.

Johnson KC, Koestler DC, Cheng C, Christensen BC.

Epigenetics. 2014 Feb;9(2):268-75. doi: 10.4161/epi.27015. Epub 2013 Nov 6.

43.

Developmental genes targeted for epigenetic variation between twin-twin transfusion syndrome children.

Marsit CJ, Koestler DC, Watson-Smith D, Boney CM, Padbury JF, Luks F.

Clin Epigenetics. 2013 Oct 3;5(1):18. doi: 10.1186/1868-7083-5-18.

44.

Review of processing and analysis methods for DNA methylation array data.

Wilhelm-Benartzi CS, Koestler DC, Karagas MR, Flanagan JM, Christensen BC, Kelsey KT, Marsit CJ, Houseman EA, Brown R.

Br J Cancer. 2013 Sep 17;109(6):1394-402. doi: 10.1038/bjc.2013.496. Epub 2013 Aug 27. Review.

45.

Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors.

Lesseur C, Armstrong DA, Paquette AG, Koestler DC, Padbury JF, Marsit CJ.

Mol Cell Endocrinol. 2013 Dec 5;381(1-2):160-7. doi: 10.1016/j.mce.2013.07.024. Epub 2013 Jul 30.

46.

Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis.

Koestler DC, Christensen B, Karagas MR, Marsit CJ, Langevin SM, Kelsey KT, Wiencke JK, Houseman EA.

Epigenetics. 2013 Aug;8(8):816-26. doi: 10.4161/epi.25430. Epub 2013 Jun 25.

47.

Placental HTR2A methylation is associated with infant neurobehavioral outcomes.

Paquette AG, Lesseur C, Armstrong DA, Koestler DC, Appleton AA, Lester BM, Marsit CJ.

Epigenetics. 2013 Aug;8(8):796-801. doi: 10.4161/epi.25358. Epub 2013 Jun 19.

48.

Distinct patterns of DNA methylation in conventional adenomas involving the right and left colon.

Koestler DC, Li J, Baron JA, Tsongalis GJ, Butterly LF, Goodrich M, Lesseur C, Karagas MR, Marsit CJ, Moore JH, Andrew AS, Srivastava A.

Mod Pathol. 2014 Jan;27(1):145-55. doi: 10.1038/modpathol.2013.104. Epub 2013 Jul 19.

49.

Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study.

Fei DL, Koestler DC, Li Z, Giambelli C, Sanchez-Mejias A, Gosse JA, Marsit CJ, Karagas MR, Robbins DJ.

Environ Health. 2013 Jul 16;12:58. doi: 10.1186/1476-069X-12-58.

50.

Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero.

Koestler DC, Avissar-Whiting M, Houseman EA, Karagas MR, Marsit CJ.

Environ Health Perspect. 2013 Aug;121(8):971-7. doi: 10.1289/ehp.1205925. Epub 2013 Jun 11.

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