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Items: 21

1.

Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation.

LaHaye S, Majumdar U, Yasuhara J, Koenig SN, Matos-Nieves A, Kumar R, Garg V.

Dis Model Mech. 2019 Jun 24;12(6). pii: dmm036764. doi: 10.1242/dmm.036764.

2.

Defining new mechanistic roles for αII spectrin in cardiac function.

Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud G, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, Cavus O, Simmons SL, Williams JL, Skaf M, Koenig SN, Janssen PML, Rasband MN, Hund TJ, Mohler PJ.

J Biol Chem. 2019 Jun 14;294(24):9576-9591. doi: 10.1074/jbc.RA119.007714. Epub 2019 May 7.

PMID:
31064843
3.

MG 53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling.

Adesanya TMA, Russell M, Park KH, Zhou X, Sermersheim MA, Gumpper K, Koenig SN, Tan T, Whitson BA, Janssen PML, Lincoln J, Zhu H, Ma J.

J Am Heart Assoc. 2019 Feb 19;8(4):e009960. doi: 10.1161/JAHA.118.009960.

4.

Protein Phosphatase 2A Regulates Cardiac Na+ Channels.

El Refaey M, Musa H, Murphy NP, Lubbers ER, Skaf M, Han M, Cavus O, Koenig SN, Wallace MJ, Gratz D, Bradley E, Alsina KM, Wehrens XHT, Hund TJ, Mohler PJ.

Circ Res. 2019 Mar;124(5):737-746. doi: 10.1161/CIRCRESAHA.118.314350.

PMID:
30602331
5.

Potential use of ivabradine for treatment of atrial fibrillation.

Koenig SN, Mohler PJ.

J Cardiovasc Electrophysiol. 2019 Feb;30(2):253-254. doi: 10.1111/jce.13788. Epub 2018 Nov 28. No abstract available.

PMID:
30427090
6.

βIV-Spectrin regulates STAT3 targeting to tune cardiac response to pressure overload.

Unudurthi SD, Nassal D, Greer-Short A, Patel N, Howard T, Xu X, Onal B, Satroplus T, Hong D, Lane C, Dalic A, Koenig SN, Lehnig AC, Baer LA, Musa H, Stanford KI, Smith S, Mohler PJ, Hund TJ.

J Clin Invest. 2018 Dec 3;128(12):5561-5572. doi: 10.1172/JCI99245. Epub 2018 Nov 12.

7.

Corrigendum to "Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease" [J. Mol. Cell. Cardiol. 60 (2013) 27-35].

Bosse K, Hans CP, Zhao N, Koenig SN, Huang N, Guggilam A, LaHaye S, Tao G, Lucchesi PA, Lincoln J, Lilly B, Garg V.

J Mol Cell Cardiol. 2018 Aug;121:307. doi: 10.1016/j.yjmcc.2018.04.013. Epub 2018 May 31. No abstract available.

PMID:
29778253
8.

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.

Koenig SN, LaHaye S, Feller JD, Rowland P, Hor KN, Trask AJ, Janssen PM, Radtke F, Lilly B, Garg V.

JCI Insight. 2017 Nov 2;2(21). pii: 91353. doi: 10.1172/jci.insight.91353.

9.

The evolving role of ankyrin-B in cardiovascular disease.

Koenig SN, Mohler PJ.

Heart Rhythm. 2017 Dec;14(12):1884-1889. doi: 10.1016/j.hrthm.2017.07.032. Epub 2017 Jul 29. Review.

10.

Genetic basis of aortic valvular disease.

Koenig SN, Lincoln J, Garg V.

Curr Opin Cardiol. 2017 Feb 2. doi: 10.1097/HCO.0000000000000384. [Epub ahead of print]

11.

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract.

Koenig SN, Bosse K, Majumdar U, Bonachea EM, Radtke F, Garg V.

J Am Heart Assoc. 2016 Apr 22;5(4). pii: e003075. doi: 10.1161/JAHA.115.003075.

12.

Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and Disease.

Horne TE, VandeKopple M, Sauls K, Koenig SN, Anstine LJ, Garg V, Norris RA, Lincoln J.

J Cardiovasc Dev Dis. 2015 Sep;2(3):214-232. doi: 10.3390/jcdd2030214. Epub 2015 Aug 17.

13.

Evidence of Aortopathy in Mice with Haploinsufficiency of Notch1 in Nos3-Null Background.

Koenig SN, Bosse KM, Nadorlik HA, Lilly B, Garg V.

J Cardiovasc Dev Dis. 2015;2(1):17-30.

14.

Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model.

Cheng J, Koenig SN, Kuivaniemi HS, Garg V, Hans CP.

J Am Heart Assoc. 2014 Oct 27;3(6):e001064. doi: 10.1161/JAHA.114.001064.

15.

MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.

Zhao N, Koenig SN, Trask AJ, Lin CH, Hans CP, Garg V, Lilly B.

Circ Res. 2015 Jan 2;116(1):23-34. doi: 10.1161/CIRCRESAHA.115.303970. Epub 2014 Oct 16.

16.

Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.

Bosse K, Hans CP, Zhao N, Koenig SN, Huang N, Guggilam A, LaHaye S, Tao G, Lucchesi PA, Lincoln J, Lilly B, Garg V.

J Mol Cell Cardiol. 2013 Jul;60:27-35. doi: 10.1016/j.yjmcc.2013.04.001. Epub 2013 Apr 11. Erratum in: J Mol Cell Cardiol. 2018 May 16;:.

17.

Inhibition of Notch1 signaling reduces abdominal aortic aneurysm in mice by attenuating macrophage-mediated inflammation.

Hans CP, Koenig SN, Huang N, Cheng J, Beceiro S, Guggilam A, Kuivaniemi H, Partida-Sánchez S, Garg V.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):3012-23. doi: 10.1161/ATVBAHA.112.254219. Epub 2012 Oct 18.

18.

Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.

Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V.

PLoS Genet. 2012;8(5):e1002690. doi: 10.1371/journal.pgen.1002690. Epub 2012 May 10.

19.

Submicroscopic chromosomal copy number variations identified in children with hypoplastic left heart syndrome.

Payne AR, Chang SW, Koenig SN, Zinn AR, Garg V.

Pediatr Cardiol. 2012 Jun;33(5):757-63. doi: 10.1007/s00246-012-0208-9. Epub 2012 Feb 21.

PMID:
22349727
20.

Inhibitory role of Notch1 in calcific aortic valve disease.

Acharya A, Hans CP, Koenig SN, Nichols HA, Galindo CL, Garner HR, Merrill WH, Hinton RB, Garg V.

PLoS One. 2011;6(11):e27743. doi: 10.1371/journal.pone.0027743. Epub 2011 Nov 16.

21.

Identification of GATA6 sequence variants in patients with congenital heart defects.

Maitra M, Koenig SN, Srivastava D, Garg V.

Pediatr Res. 2010 Oct;68(4):281-5. doi: 10.1203/00006450-201011001-00549.

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