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Items: 1 to 50 of 164

1.

Human CD4+ T cells specific for Merkel cell polyomavirus localize to Merkel cell carcinomas and target a required oncogenic domain.

Longino NV, Yang J, Iyer JG, Ibrani D, Chow IT, Laing KJ, Campbell VL, Paulson KG, Kulikauskas RM, Church CD, James EA, Nghiem P, Kwok WW, Koelle DM.

Cancer Immunol Res. 2019 Aug 12. pii: canimm.0103.2019. doi: 10.1158/2326-6066.CIR-19-0103. [Epub ahead of print]

PMID:
31405946
2.

Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates.

Yu KKQ, Wilburn DB, Hackney JA, Darrah PA, Foulds KE, James CA, Smith MT, Jing L, Seder RA, Roederer M, Koelle DM, Swanson WJ, Seshadri C.

Immunogenetics. 2019 Jul;71(7):465-478. doi: 10.1007/s00251-019-01118-9. Epub 2019 May 23.

3.

A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus (HSV) Type 2 Vaccine, HSV529, in Adults With or Without HSV Infection.

Dropulic LK, Oestreich MC, Pietz HL, Laing KJ, Hunsberger S, Lumbard K, Garabedian D, Turk SP, Chen A, Hornung RL, Seshadri C, Smith MT, Hosken NA, Phogat S, Chang LJ, Koelle DM, Wang K, Cohen JI.

J Infect Dis. 2019 Aug 9;220(6):990-1000. doi: 10.1093/infdis/jiz225.

PMID:
31058977
4.

Genome-Wide Approach to the CD4 T-Cell Response to Human Herpesvirus 6B.

Hanson DJ, Tsvetkova O, Rerolle GF, Greninger AL, Sette A, Jing L, Campbell VL, Koelle DM.

J Virol. 2019 Jun 28;93(14). pii: e00321-19. doi: 10.1128/JVI.00321-19. Print 2019 Jul 15.

PMID:
31043533
5.

Large, stable, contemporary interspecies recombination events in circulating human herpes simplex viruses.

Casto AM, Roychoudhury P, Xie H, Selke S, Perchetti GA, Wofford H, Huang ML, Verjans GMGM, Gottlieb GS, Wald A, Jerome KR, Koelle DM, Johnston C, Greninger AL.

J Infect Dis. 2019 Apr 23. pii: jiz199. doi: 10.1093/infdis/jiz199. [Epub ahead of print]

PMID:
31016321
6.

Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense.

Hung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED.

J Immunol. 2019 May 1;202(9):2558-2569. doi: 10.4049/jimmunol.1801454. Epub 2019 Mar 29.

PMID:
30926644
7.

Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function.

Jones D, Como CN, Jing L, Blackmon A, Neff CP, Krueger O, Bubak AN, Palmer BE, Koelle DM, Nagel MA.

PLoS Pathog. 2019 Mar 14;15(3):e1007650. doi: 10.1371/journal.ppat.1007650. eCollection 2019 Mar.

8.

A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize.

Yang J, Jing L, James EA, Gebe JA, Koelle DM, Kwok WW.

Front Immunol. 2018 Dec 3;9:2811. doi: 10.3389/fimmu.2018.02811. eCollection 2018.

9.

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

Bentzen AK, Such L, Jensen KK, Marquard AM, Jessen LE, Miller NJ, Church CD, Lyngaa R, Koelle DM, Becker JC, Linnemann C, Schumacher TNM, Marcatili P, Nghiem P, Nielsen M, Hadrup SR.

Nat Biotechnol. 2018 Nov 19. doi: 10.1038/nbt.4303. [Epub ahead of print]

PMID:
30451992
10.

Viral Genetics Modulate Orolabial Herpes Simplex Virus Type 1 Shedding in Humans.

Ramchandani MS, Jing L, Russell RM, Tran T, Laing KJ, Magaret AS, Selke S, Cheng A, Huang ML, Xie H, Strachan E, Greninger AL, Roychoudhury P, Jerome KR, Wald A, Koelle DM.

J Infect Dis. 2019 Mar 15;219(7):1058-1066. doi: 10.1093/infdis/jiy631.

PMID:
30383234
11.

Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques.

Lo M, Zhu J, Hansen SG, Carroll T, Farr Zuend C, Nöel-Romas L, Ma ZM, Fritts L, Huang ML, Sun S, Huang Y, Koelle DM, Picker LJ, Burgener A, Corey L, Miller CJ.

J Virol. 2019 Jan 4;93(2). pii: e01574-18. doi: 10.1128/JVI.01574-18. Print 2019 Jan 15.

12.

Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA.

Paulson KG, Voillet V, McAfee MS, Hunter DS, Wagener FD, Perdicchio M, Valente WJ, Koelle SJ, Church CD, Vandeven N, Thomas H, Colunga AG, Iyer JG, Yee C, Kulikauskas R, Koelle DM, Pierce RH, Bielas JH, Greenberg PD, Bhatia S, Gottardo R, Nghiem P, Chapuis AG.

Nat Commun. 2018 Sep 24;9(1):3868. doi: 10.1038/s41467-018-06300-3.

13.

Immunobiology of Varicella-Zoster Virus Infection.

Laing KJ, Ouwendijk WJD, Koelle DM, Verjans GMGM.

J Infect Dis. 2018 Sep 22;218(suppl_2):S68-S74. doi: 10.1093/infdis/jiy403. Erratum in: J Infect Dis. 2019 Apr 16;219(9):1514.

PMID:
30247598
14.

Risk Factors for Indeterminate Outcome on Interferon Gamma Release Assay in Non-US-Born Persons Screened for Latent Tuberculosis Infection.

Sharninghausen JC, Shapiro AE, Koelle DM, Kim HN.

Open Forum Infect Dis. 2018 Jul 27;5(8):ofy184. doi: 10.1093/ofid/ofy184. eCollection 2018 Aug.

15.

Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma.

Bhatia S, Miller NJ, Lu H, Longino NV, Ibrani D, Shinohara MM, Byrd DR, Parvathaneni U, Kulikauskas R, Ter Meulen J, Hsu FJ, Koelle DM, Nghiem P.

Clin Cancer Res. 2019 Feb 15;25(4):1185-1195. doi: 10.1158/1078-0432.CCR-18-0469. Epub 2018 Aug 9.

PMID:
30093453
16.

Advances in the Characterization of the T-Cell Response to Human Herpesvirus-6.

Hanson DJ, Hill JA, Koelle DM.

Front Immunol. 2018 Jun 25;9:1454. doi: 10.3389/fimmu.2018.01454. eCollection 2018. Review.

17.

Genome-Wide Surveillance of Genital Herpes Simplex Virus Type 1 From Multiple Anatomic Sites Over Time.

Shipley MM, Renner DW, Ott M, Bloom DC, Koelle DM, Johnston C, Szpara ML.

J Infect Dis. 2018 Jul 13;218(4):595-605. doi: 10.1093/infdis/jiy216.

18.

Ultrasensitive Capture of Human Herpes Simplex Virus Genomes Directly from Clinical Samples Reveals Extraordinarily Limited Evolution in Cell Culture.

Greninger AL, Roychoudhury P, Xie H, Casto A, Cent A, Pepper G, Koelle DM, Huang ML, Wald A, Johnston C, Jerome KR.

mSphere. 2018 Jun 13;3(3). pii: e00283-18. doi: 10.1128/mSphereDirect.00283-18. Print 2018 Jun 27.

19.

Multicenter study of QuantiFERON®-TB Gold Plus in patients with active tuberculosis.

Horne DJ, Jones BE, Kamada A, Fukushima K, Winthrop KL, Siegel SAR, Kovacs A, Anthony P, Meekin KA, Bhat S, Kerndt P, Chang A, Koelle DM, Narita M.

Int J Tuberc Lung Dis. 2018 Jun 1;22(6):617-621. doi: 10.5588/ijtld.17.0721.

PMID:
29862944
20.

HHV-6B infection, T-cell reconstitution, and graft-vs-host disease after hematopoietic stem cell transplantation.

Phan TL, Pritchett JC, Leifer C, Zerr DM, Koelle DM, Di Luca D, Lusso P.

Bone Marrow Transplant. 2018 Dec;53(12):1508-1517. doi: 10.1038/s41409-018-0225-2. Epub 2018 May 24. Review.

PMID:
29795424
21.

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6.

Greninger AL, Knudsen GM, Roychoudhury P, Hanson DJ, Sedlak RH, Xie H, Guan J, Nguyen T, Peddu V, Boeckh M, Huang ML, Cook L, Depledge DP, Zerr DM, Koelle DM, Gantt S, Yoshikawa T, Caserta M, Hill JA, Jerome KR.

BMC Genomics. 2018 Mar 20;19(1):204. doi: 10.1186/s12864-018-4604-2.

22.

Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2).

Kleinstein SE, Shea PR, Allen AS, Koelle DM, Wald A, Goldstein DB.

Genes Immun. 2019 Feb;20(2):112-120. doi: 10.1038/s41435-018-0013-4. Epub 2018 Feb 28.

23.

Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains.

Greninger AL, Roychoudhury P, Makhsous N, Hanson D, Chase J, Krueger G, Xie H, Huang ML, Saunders L, Ablashi D, Koelle DM, Cook L, Jerome KR.

J Virol. 2018 Apr 27;92(10). pii: e00135-18. doi: 10.1128/JVI.00135-18. Print 2018 May 15.

24.

Dual-strain genital herpes simplex virus type 2 (HSV-2) infection in the US, Peru, and 8 countries in sub-Saharan Africa: A nested cross-sectional viral genotyping study.

Johnston C, Magaret A, Roychoudhury P, Greninger AL, Reeves D, Schiffer J, Jerome KR, Sather C, Diem K, Lingappa JR, Celum C, Koelle DM, Wald A.

PLoS Med. 2017 Dec 27;14(12):e1002475. doi: 10.1371/journal.pmed.1002475. eCollection 2017 Dec.

25.

Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques.

Aravantinou M, Mizenina O, Calenda G, Kenney J, Frank I, Lifson JD, Szpara M, Jing L, Koelle DM, Teleshova N, Grasperge B, Blanchard J, Gettie A, Martinelli E, Derby N.

Front Microbiol. 2017 Dec 5;8:2342. doi: 10.3389/fmicb.2017.02342. eCollection 2017.

26.

Patients with atopic dermatitis and history of eczema herpeticum elicit herpes simplex virus-specific type 2 immune responses.

Traidl S, Kienlin P, Begemann G, Jing L, Koelle DM, Werfel T, Roesner LM.

J Allergy Clin Immunol. 2018 Mar;141(3):1144-1147.e5. doi: 10.1016/j.jaci.2017.09.048. Epub 2017 Nov 16. No abstract available.

PMID:
29155096
27.
28.

Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects.

Abana CO, Pilkinton MA, Gaudieri S, Chopra A, McDonnell WJ, Wanjalla C, Barnett L, Gangula R, Hager C, Jung DK, Engelhardt BG, Jagasia MH, Klenerman P, Phillips EJ, Koelle DM, Kalams SA, Mallal SA.

J Immunol. 2017 Nov 1;199(9):3187-3201. doi: 10.4049/jimmunol.1700851. Epub 2017 Oct 2.

29.

Highly conserved intragenic HSV-2 sequences: Results from next-generation sequencing of HSV-2 UL and US regions from genital swabs collected from 3 continents.

Johnston C, Magaret A, Roychoudhury P, Greninger AL, Cheng A, Diem K, Fitzgibbon MP, Huang ML, Selke S, Lingappa JR, Celum C, Jerome KR, Wald A, Koelle DM.

Virology. 2017 Oct;510:90-98. doi: 10.1016/j.virol.2017.06.031. Epub 2017 Jul 13.

30.

Selective Expression of CCR10 and CXCR3 by Circulating Human Herpes Simplex Virus-Specific CD8 T Cells.

Hensel MT, Peng T, Cheng A, De Rosa SC, Wald A, Laing KJ, Jing L, Dong L, Magaret AS, Koelle DM.

J Virol. 2017 Sep 12;91(19). pii: e00810-17. doi: 10.1128/JVI.00810-17. Print 2017 Oct 1.

31.

Elevated Spontaneous Interferon-γ Secretion in Human Immunodeficiency Virus-Infected Persons.

Sparks R, Koelle DM, Stern JE, Dhanireddy S.

Open Forum Infect Dis. 2017 Jun 7;4(2):ofx055. doi: 10.1093/ofid/ofx055. eCollection 2017 Spring.

32.

T-cell Responses to HSV-1 in Persons Who Have Survived Childhood Herpes Simplex Encephalitis.

Ott M, Jing L, Lorenzo L, Casanova JL, Zhang SY, Koelle DM.

Pediatr Infect Dis J. 2017 Aug;36(8):741-744. doi: 10.1097/INF.0000000000001631.

33.

Worldwide circulation of HSV-2 × HSV-1 recombinant strains.

Koelle DM, Norberg P, Fitzgibbon MP, Russell RM, Greninger AL, Huang ML, Stensland L, Jing L, Magaret AS, Diem K, Selke S, Xie H, Celum C, Lingappa JR, Jerome KR, Wald A, Johnston C.

Sci Rep. 2017 Mar 13;7:44084. doi: 10.1038/srep44084.

34.

Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival.

Miller NJ, Church CD, Dong L, Crispin D, Fitzgibbon MP, Lachance K, Jing L, Shinohara M, Gavvovidis I, Willimsky G, McIntosh M, Blankenstein T, Koelle DM, Nghiem P.

Cancer Immunol Res. 2017 Feb;5(2):137-147. doi: 10.1158/2326-6066.CIR-16-0210. Epub 2017 Jan 16.

35.

Enrichment of herpes simplex virus type 2 (HSV-2) reactive mucosal T cells in the human female genital tract.

Posavad CM, Zhao L, Dong L, Jin L, Stevens CE, Magaret AS, Johnston C, Wald A, Zhu J, Corey L, Koelle DM.

Mucosal Immunol. 2017 Sep;10(5):1259-1269. doi: 10.1038/mi.2016.118. Epub 2017 Jan 4.

36.

T Cell Immunity to Varicella-Zoster Virus in the Setting of Advanced HIV and Multiple Varicella-Zoster Virus Recurrences.

Bender Ignacio RA, Ramchandani MS, Laing KJ, Johnston CM, Koelle DM.

Viral Immunol. 2017 Jan/Feb;30(1):77-80. doi: 10.1089/vim.2016.0097. Epub 2016 Nov 21.

37.

HLA Class I and II alleles, heterozygosity and HLA-KIR interactions are associated with rates of genital HSV shedding and lesions.

Magaret A, Dong L, John M, Mallal SA, James I, Warren T, Gaudieri S, Koelle DM, Wald A.

Genes Immun. 2016 Dec;17(7):412-418. doi: 10.1038/gene.2016.42. Epub 2016 Nov 17.

38.

In Situ Detection of Regulatory T Cells in Human Genital Herpes Simplex Virus Type 2 (HSV-2) Reactivation and Their Influence on Spontaneous HSV-2 Reactivation.

Milman N, Zhu J, Johnston C, Cheng A, Magaret A, Koelle DM, Huang ML, Jin L, Klock A, Layton ED, Corey L.

J Infect Dis. 2016 Jul 1;214(1):23-31. doi: 10.1093/infdis/jiw091. Epub 2016 Apr 25.

39.

Stability of live attenuated rotavirus vaccine with selected preservatives and primary containers.

Lal M, Jarrahian C, Zhu C, Hosken NA, McClurkan CL, Koelle DM, Saxon E, Roehrig A, Zehrung D, Chen D.

Vaccine. 2016 May 11;34(22):2483-9. doi: 10.1016/j.vaccine.2016.03.093. Epub 2016 Apr 13.

PMID:
27085171
40.

Latent Tuberculosis Infection Test Agreement in the National Health and Nutrition Examination Survey.

Ghassemieh BJ, Attia EF, Koelle DM, Mancuso JD, Narita M, Horne DJ.

Am J Respir Crit Care Med. 2016 Aug 15;194(4):493-500. doi: 10.1164/rccm.201508-1560OC.

41.

Extensive CD4 and CD8 T Cell Cross-Reactivity between Alphaherpesviruses.

Jing L, Laing KJ, Dong L, Russell RM, Barlow RS, Haas JG, Ramchandani MS, Johnston C, Buus S, Redwood AJ, White KD, Mallal SA, Phillips EJ, Posavad CM, Wald A, Koelle DM.

J Immunol. 2016 Mar 1;196(5):2205-2218. doi: 10.4049/jimmunol.1502366. Epub 2016 Jan 25.

42.

A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.

Odegard JM, Flynn PA, Campbell DJ, Robbins SH, Dong L, Wang K, Ter Meulen J, Cohen JI, Koelle DM.

Vaccine. 2016 Jan 2;34(1):101-9. doi: 10.1016/j.vaccine.2015.10.137. Epub 2015 Nov 10.

43.
44.

Genome Sequencing and Analysis of Geographically Diverse Clinical Isolates of Herpes Simplex Virus 2.

Newman RM, Lamers SL, Weiner B, Ray SC, Colgrove RC, Diaz F, Jing L, Wang K, Saif S, Young S, Henn M, Laeyendecker O, Tobian AA, Cohen JI, Koelle DM, Quinn TC, Knipe DM.

J Virol. 2015 Aug;89(16):8219-32. doi: 10.1128/JVI.01303-15. Epub 2015 May 27.

45.

Global Diversity within and between Human Herpesvirus 1 and 2 Glycoproteins.

Lamers SL, Newman RM, Laeyendecker O, Tobian AA, Colgrove RC, Ray SC, Koelle DM, Cohen J, Knipe DM, Quinn TC.

J Virol. 2015 Aug;89(16):8206-18. doi: 10.1128/JVI.01302-15. Epub 2015 May 27.

46.

Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.

Nayak K, Jing L, Russell RM, Davies DH, Hermanson G, Molina DM, Liang X, Sherman DR, Kwok WW, Yang J, Kenneth J, Ahamed SF, Chandele A, Murali-Krishna K, Koelle DM.

Tuberculosis (Edinb). 2015 May;95(3):275-87. doi: 10.1016/j.tube.2015.03.001. Epub 2015 Mar 27.

47.

Zoster Vaccination Increases the Breadth of CD4+ T Cells Responsive to Varicella Zoster Virus.

Laing KJ, Russell RM, Dong L, Schmid DS, Stern M, Magaret A, Haas JG, Johnston C, Wald A, Koelle DM.

J Infect Dis. 2015 Oct 1;212(7):1022-31. doi: 10.1093/infdis/jiv164. Epub 2015 Mar 17.

48.

Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system.

White JA, Blum JS, Hosken NA, Marshak JO, Duncan L, Zhu C, Norton EB, Clements JD, Koelle DM, Chen D, Weldon WC, Oberste MS, Lal M.

Hum Vaccin Immunother. 2014;10(12):3611-21. doi: 10.4161/hv.32253.

49.

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma.

Paulson KG, Tegeder A, Willmes C, Iyer JG, Afanasiev OK, Schrama D, Koba S, Thibodeau R, Nagase K, Simonson WT, Seo A, Koelle DM, Madeleine M, Bhatia S, Nakajima H, Sano S, Hardwick JS, Disis ML, Cleary MA, Becker JC, Nghiem P.

Cancer Immunol Res. 2014 Nov;2(11):1071-9. doi: 10.1158/2326-6066.CIR-14-0005. Epub 2014 Aug 12.

50.

The murine intravaginal HSV-2 challenge model for investigation of DNA vaccines.

Marshak JO, Dong L, Koelle DM.

Methods Mol Biol. 2014;1144:305-27. doi: 10.1007/978-1-4939-0428-0_21.

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