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Efficacy of water spray for evaporative cooling in athletes with spinal cord injury.

Trbovich M, Koek W, Ortega C.

Spinal Cord Ser Cases. 2019 May 28;5:51. doi: 10.1038/s41394-019-0194-8. eCollection 2019.


Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent.

Patil M, Hovhannisyan AH, Wangzhou A, Mecklenburg J, Koek W, Goffin V, Grattan D, Boehm U, Dussor G, Price TJ, Akopian AN.

J Neuroendocrinol. 2019 Aug;31(8):e12759. doi: 10.1111/jne.12759. Epub 2019 Jul 4.


Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter.

Fraser-Spears R, Krause-Heuer AM, Basiouny M, Mayer FP, Manishimwe R, Wyatt NA, Dobrowolski JC, Roberts MP, Greguric I, Kumar N, Koek W, Sitte HH, Callaghan PD, Fraser BH, Daws LC.

Eur J Pharmacol. 2019 Jan 5;842:351-364. doi: 10.1016/j.ejphar.2018.10.028. Epub 2018 Oct 25.


Pharmacokinetics of Phosphatidylethanol 16:0/20:4 in Human Blood After Alcohol Intake.

Lopez-Cruzan M, Roache JD, Hill-Kapturczak N, Karns-Wright TE, Dougherty DM, Sanchez JJ, Koek W, Javors MA.

Alcohol Clin Exp Res. 2018 Nov;42(11):2094-2099. doi: 10.1111/acer.13865. Epub 2018 Aug 26.


Constitutive plasma membrane monoamine transporter (PMAT, Slc29a4) deficiency subtly affects anxiety-like and coping behaviours.

Gilman TL, George CM, Vitela M, Herrera-Rosales M, Basiouny MS, Koek W, Daws LC.

Eur J Neurosci. 2018 May 24. doi: 10.1111/ejn.13968. [Epub ahead of print]


An unsuspected role for organic cation transporter 3 in the actions of amphetamine.

Mayer FP, Schmid D, Owens WA, Gould GG, Apuschkin M, Kudlacek O, Salzer I, Boehm S, Chiba P, Williams PH, Wu HH, Gether U, Koek W, Daws LC, Sitte HH.

Neuropsychopharmacology. 2018 Nov;43(12):2408-2417. doi: 10.1038/s41386-018-0053-5. Epub 2018 Apr 6.


A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects.

Kraig E, Linehan LA, Liang H, Romo TQ, Liu Q, Wu Y, Benavides AD, Curiel TJ, Javors MA, Musi N, Chiodo L, Koek W, Gelfond JAL, Kellogg DL Jr.

Exp Gerontol. 2018 May;105:53-69. doi: 10.1016/j.exger.2017.12.026. Epub 2018 Feb 3.


NLX-112, a highly selective 5-HT1A receptor agonist: Effects on body temperature and plasma corticosterone levels in rats.

Newman-Tancredi A, Depoortère R, Carilla-Durand E, Tarayre JP, Kleven M, Koek W, Bardin L, Varney MA.

Pharmacol Biochem Behav. 2018 Feb;165:56-62. doi: 10.1016/j.pbb.2017.11.002. Epub 2017 Nov 7.


Effects of local and spinal administrations of mu-opioids on postoperative pain in aged versus adult mice.

Mecklenburg J, Patil MJ, Koek W, Akopian AN.

Pain Rep. 2017 Jan;2(1):e584. doi: 10.1097/PR9.0000000000000584.


Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22.

Krause-Heuer AM, Fraser-Spears R, Dobrowolski JC, Ashford ME, Wyatt NA, Roberts MP, Gould GG, Cheah WC, Ng CKL, Bhadbhade M, Zhang B, Greguric I, Wheate NJ, Kumar N, Koek W, Callaghan PD, Daws LC, Fraser BH.

Eur J Med Chem. 2017 Sep 8;137:476-487. doi: 10.1016/j.ejmech.2017.06.011. Epub 2017 Jun 7.


Thermoreversible Cross-Linking of Furan-Containing Ethylene/Vinyl Acetate Rubber with Bismaleimide.

Polgar LM, Hagting E, Koek WJ, Picchioni F, Van Duin M.

Polymers (Basel). 2017 Feb 25;9(3). pii: E81. doi: 10.3390/polym9030081.


Serum Phosphate Is Associated With Fracture Risk: The Rotterdam Study and MrOS.

Campos-Obando N, Koek WNH, Hooker ER, van der Eerden BC, Pols HA, Hofman A, van Leeuwen JP, Uitterlinden AG, Nielson CM, Zillikens MC.

J Bone Miner Res. 2017 Jun;32(6):1182-1193. doi: 10.1002/jbmr.3094. Epub 2017 Mar 27.


Osteoclastogenic capacity of peripheral blood mononuclear cells is not different between women with and without osteoporosis.

Koek WNH, van der Eerden BCJ, Alves RDAM, van Driel M, Schreuders-Koedam M, Zillikens MC, van Leeuwen JPTM.

Bone. 2017 Feb;95:108-114. doi: 10.1016/j.bone.2016.11.010. Epub 2016 Nov 12.


Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice.

Mitchell NC, Bowman MA, Gould GG, Koek W, Daws LC.

J Pharmacol Exp Ther. 2017 Jan;360(1):84-94. Epub 2016 Nov 9.


Novel Compound Heterozygous Mutations in the CYP27B1 Gene Lead to Pseudovitamin D-Deficient Rickets.

Koek WN, Zillikens MC, van der Eerden BC, van Leeuwen JP.

Calcif Tissue Int. 2016 Sep;99(3):326-31. doi: 10.1007/s00223-016-0165-z. Epub 2016 Jul 1.


Ontogeny of SERT Expression and Antidepressant-like Response to Escitalopram in Wild-Type and SERT Mutant Mice.

Mitchell NC, Gould GG, Koek W, Daws LC.

J Pharmacol Exp Ther. 2016 Aug;358(2):271-81. doi: 10.1124/jpet.116.233338. Epub 2016 Jun 10.


Effects of nicotine in combination with drugs described as positive allosteric nicotinic acetylcholine receptor modulators in vitro: discriminative stimulus and hypothermic effects in mice.

Moerke MJ, de Moura FB, Koek W, McMahon LR.

Eur J Pharmacol. 2016 Sep 5;786:169-178. doi: 10.1016/j.ejphar.2016.05.032. Epub 2016 May 27.


Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism.

van der Eerden BC, Koek WN, Roschger P, Zillikens MC, Waarsing JH, van der Kemp A, Schreuders-Koedam M, Fratzl-Zelman N, Leenen PJ, Hoenderop JG, Klaushofer K, Bindels RJ, van Leeuwen JP.

Oncotarget. 2016 May 3;7(18):24928-41. doi: 10.18632/oncotarget.8779.


Antidepressant-like effects and basal immobility depend on age and serotonin transporter genotype.

Mitchell NC, Koek W, Daws LC.

Genes Brain Behav. 2015 Sep;14(7):543-549. doi: 10.1111/gbb.12238.


Effects of consuming a diet high in fat and/or sugar on the locomotor effects of acute and repeated cocaine in male and female C57BL/6J mice.

Collins GT, Chen Y, Tschumi C, Rush EL, Mensah A, Koek W, France CP.

Exp Clin Psychopharmacol. 2015 Aug;23(4):228-37. doi: 10.1037/pha0000019.


Cross-tolerance to cannabinoids in morphine-tolerant rhesus monkeys.

Gerak LR, Zanettini C, Koek W, France CP.

Psychopharmacology (Berl). 2015 Oct;232(19):3637-47. doi: 10.1007/s00213-015-4023-x. Epub 2015 Jul 23.


Drinking sucrose or saccharin enhances sensitivity of rats to quinpirole-induced yawning.

Serafine KM, Bentley TA, Kilborn DJ, Koek W, France CP.

Eur J Pharmacol. 2015 Oct 5;764:529-36. doi: 10.1016/j.ejphar.2015.07.036. Epub 2015 Jul 17.


Effects of amphetamine, morphine, and CP 55, 940 on Go/No-Go task performance in rhesus monkeys.

Koek W, Gerak LR, France CP.

Behav Pharmacol. 2015 Aug;26(5):481-4. doi: 10.1097/FBP.0000000000000146.


NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat.

Iderberg H, McCreary AC, Varney MA, Kleven MS, Koek W, Bardin L, Depoortère R, Cenci MA, Newman-Tancredi A.

Exp Neurol. 2015 Sep;271:335-50. doi: 10.1016/j.expneurol.2015.05.021. Epub 2015 May 30.


Physiological and behavioral effects of amphetamine in BACE1(-/-) mice.

Paredes RM, Piccart E, Navaira E, Cruz D, Javors MA, Koek W, Beckstead MJ, Walss-Bass C.

Genes Brain Behav. 2015 Jun;14(5):411-8. doi: 10.1111/gbb.12222. Epub 2015 May 21.


Eating high fat chow, but not drinking sucrose or saccharin, enhances the development of sensitization to the locomotor effects of cocaine in adolescent female rats.

Serafine KM, Bentley TA, Koek W, France CP.

Behav Pharmacol. 2015 Apr;26(3):321-5. doi: 10.1097/FBP.0000000000000114.


Morphine-induced conditioned place preference and effects of morphine pre-exposure in adolescent and adult male C57BL/6J mice.

Koek W.

Psychopharmacology (Berl). 2016 Jun;233(11):2015-2024. doi: 10.1007/s00213-014-3695-y. Epub 2014 Jul 29.


Effects of dopamine D(2)-like receptor agonists in mice trained to discriminate cocaine from saline: influence of feeding condition.

Collins GT, Jackson JA, Koek W, France CP.

Eur J Pharmacol. 2014 Apr 15;729:123-31. doi: 10.1016/j.ejphar.2014.02.014. Epub 2014 Feb 20.


Antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: Relationship with hippocampal serotonin and norepinephrine transporter expression and function.

Mitchell NC, Gould GG, Smolik CM, Koek W, Daws LC.

Front Pharmacol. 2013 Oct 28;4:131. doi: 10.3389/fphar.2013.00131. eCollection 2013.


Catecholamine/Serotonin interactions: systems thinking for brain function and disease.

Hensler JG, Artigas F, Bortolozzi A, Daws LC, De Deurwaerdère P, Milan L, Navailles S, Koek W.

Adv Pharmacol. 2013;68:167-97. doi: 10.1016/B978-0-12-411512-5.00009-9. Review.


Decynium-22 enhances SSRI-induced antidepressant-like effects in mice: uncovering novel targets to treat depression.

Horton RE, Apple DM, Owens WA, Baganz NL, Cano S, Mitchell NC, Vitela M, Gould GG, Koek W, Daws LC.

J Neurosci. 2013 Jun 19;33(25):10534-43. doi: 10.1523/JNEUROSCI.5687-11.2013.


Revisiting serotonin reuptake inhibitors and the therapeutic potential of "uptake-2" in psychiatric disorders.

Daws LC, Koek W, Mitchell NC.

ACS Chem Neurosci. 2013 Jan 16;4(1):16-21. doi: 10.1021/cn3001872.


Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse.

Koek W, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2013 Mar;344(3):553-60. doi: 10.1124/jpet.112.202226. Epub 2012 Dec 28.


Interactions between Δ(9)-tetrahydrocannabinol and heroin: self-administration in rhesus monkeys.

Li JX, Koek W, France CP.

Behav Pharmacol. 2012 Dec;23(8):754-61. doi: 10.1097/FBP.0b013e32835a3907.


Effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) and quipazine on heroin self-administration in rhesus monkeys.

Maguire DR, Li JX, Koek W, France CP.

Psychopharmacology (Berl). 2013 Jan;225(1):173-85. doi: 10.1007/s00213-012-2803-0. Epub 2012 Jul 27.


Eating high fat chow enhances the locomotor-stimulating effects of cocaine in adolescent and adult female rats.

Baladi MG, Koek W, Aumann M, Velasco F, France CP.

Psychopharmacology (Berl). 2012 Aug;222(3):447-57. doi: 10.1007/s00213-012-2663-7. Epub 2012 Mar 15.


Effects of the GABAB receptor-positive modulators CGP7930 and rac-BHFF in baclofen- and γ-hydroxybutyrate-discriminating pigeons.

Koek W, France CP, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2012 May;341(2):369-76. doi: 10.1124/jpet.111.190975. Epub 2012 Feb 7.


Eating high fat chow increases the sensitivity of rats to 8-OH-DPAT-induced lower lip retraction.

Li JX, Ju S, Baladi MG, Koek W, France CP.

Behav Pharmacol. 2011 Dec;22(8):751-7. doi: 10.1097/FBP.0b013e32834d0eeb.


GABAB receptor-positive modulators: brain region-dependent effects.

Hensler JG, Advani T, Burke TF, Cheng K, Rice KC, Koek W.

J Pharmacol Exp Ther. 2012 Jan;340(1):19-26. doi: 10.1124/jpet.111.186577. Epub 2011 Sep 27.


Morphine-induced motor stimulation, motor incoordination, and hypothermia in adolescent and adult mice.

Koek W, France CP, Javors MA.

Psychopharmacology (Berl). 2012 Feb;219(4):1027-37. doi: 10.1007/s00213-011-2432-z. Epub 2011 Aug 12.


Drug-induced state-dependent learning: review of an operant procedure in rats.

Koek W.

Behav Pharmacol. 2011 Sep;22(5-6):430-40. doi: 10.1097/FBP.0b013e328348ed3b. Review.


Effects of direct- and indirect-acting serotonin receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in rhesus monkeys.

Li JX, Koek W, Rice KC, France CP.

Neuropsychopharmacology. 2011 Apr;36(5):940-9. doi: 10.1038/npp.2010.232. Epub 2011 Jan 5.


Effects of serotonin (5-HT)1A and 5-HT2A receptor agonists on schedule-controlled responding in rats: drug combination studies.

Li JX, Crocker C, Koek W, Rice KC, France CP.

Psychopharmacology (Berl). 2011 Feb;213(2-3):489-97. doi: 10.1007/s00213-010-2136-9. Epub 2010 Dec 21.


GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.

Koek W, France CP, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2010 Oct;335(1):163-71. doi: 10.1124/jpet.110.171116. Epub 2010 Jul 13.


The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake.

Koek WN, van Meurs JB, van der Eerden BC, Rivadeneira F, Zillikens MC, Hofman A, Obermayer-Pietsch B, Lips P, Pols HA, Uitterlinden AG, van Leeuwen JP.

J Bone Miner Res. 2010 Sep;25(9):1980-7. doi: 10.1002/jbmr.83.


Precipitated and conditioned withdrawal in morphine-treated rats.

Becker GL, Gerak LR, Li JX, Koek W, France CP.

Psychopharmacology (Berl). 2010 Mar;209(1):85-94. doi: 10.1007/s00213-009-1773-3. Epub 2010 Feb 3.


F15599, a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity.

Assié MB, Bardin L, Auclair AL, Carilla-Durand E, Depoortère R, Koek W, Kleven MS, Colpaert F, Vacher B, Newman-Tancredi A.

Int J Neuropsychopharmacol. 2010 Nov;13(10):1285-98. doi: 10.1017/S1461145709991222. Epub 2010 Jan 11.


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