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Items: 1 to 50 of 554

1.

Administration of a 20-Hydroxyeicosatetraenoic Acid Synthesis Inhibitor Improves Outcome in a Rat Model of Pediatric Traumatic Brain Injury.

Shu S, Zhang Z, Spicer D, Kulikowicz E, Hu K, Babapoor-Farrokhran S, Kannan S, Koehler RC, Robertson CL.

Dev Neurosci. 2019 Sep 25:1-11. doi: 10.1159/000500895. [Epub ahead of print]

2.

Advancing Biologics Development Programs with Legacy Cell Lines: Advantages and Limitations of Genetic Testing for Addressing Clonality Concerns Prior to Availability of Late Stage Process and Product Consistency Data.

Wu P, Hartman T, Almond L, Stevens J, Thrift J, OJha J, Alves C, Shaw D, Laird MW, Emmins R, Zhu Y, Liu R, Du Z, Koehler R, Jostock T, Anderson K, Campbell C, Clarke H.

PDA J Pharm Sci Technol. 2019 Sep 13. pii: pdajpst.2018.009316. doi: 10.5731/pdajpst.2018.009316. [Epub ahead of print]

PMID:
31519780
3.

Surgeon Agreement on the Presence of Pathologic Anterior Instability on Shoulder Imaging Studies.

Beason AM, Koehler RJ, Sanders RA, Rode BE, Menge TJ, McCullough KA, Glass NA, Hettrich CM; MOON Shoulder Group, Cox CL, Bollier MJ, Wolf BR, Spencer EE, Grant JA, Bishop JY, Jones GL, Barlow JD, Baumgarten KM, Kelly JD, Sennett BJ, Zgonis M, Abboud JA, Namdari S, Allen C, Kuhn JE, Sullivan JP, Wright RW, Brophy RH, Smith MV, Dunn WR.

Orthop J Sports Med. 2019 Aug 9;7(8):2325967119862501. doi: 10.1177/2325967119862501. eCollection 2019 Aug.

4.

Association of diastolic blood pressure with survival during paediatric cardiopulmonary resuscitation.

O'Brien CE, Santos PT, Reyes M, Adams S, Hopkins CD, Kulikowicz E, Hamrick JL, Hamrick JT, Lee JK, Kudchadkar SR, Hunt EA, Koehler RC, Shaffner DH.

Resuscitation. 2019 Oct;143:50-56. doi: 10.1016/j.resuscitation.2019.07.030. Epub 2019 Aug 4.

PMID:
31390531
5.

The Heterogeneity of Pediatric Knee Infections: A Retrospective Analysis.

Gibian JT, Daryoush JR, Wollenman CC, Johnson SR, Henry A, Koehler RJ, Moore-Lotridge SN, Schoenecker JG.

J Pediatr Orthop. 2019 Jul 26. doi: 10.1097/BPO.0000000000001425. [Epub ahead of print]

PMID:
31386641
6.

Trade-off between pulse rate and radiation dose during modified barium swallow examination: what is the reality?

Galgano SJ, Gauntt D, Boyd MR, Trahan D, Jackson BE, Koehler RE, Canon CL, McNamara MM, Zarzour JG.

Clin Radiol. 2019 Sep;74(9):736.e9-736.e12. doi: 10.1016/j.crad.2019.05.030. Epub 2019 Jun 28.

PMID:
31256907
7.

Propentdyopents.

Koehler RC.

Circ Res. 2019 Jun 7;124(12):1686-1688. doi: 10.1161/CIRCRESAHA.119.315184. Epub 2019 Jun 6. No abstract available.

PMID:
31170044
8.

The Effect of Asphyxia Arrest Duration on a Pediatric End-Tidal CO2-Guided Chest Compression Delivery Model.

Hamrick JL, Hamrick JT, O'Brien CE, Reyes M, Santos PT, Heitmiller SE, Kulikowicz E, Lee JK, Kudchadkar SR, Koehler RC, Hunt EA, Shaffner DH.

Pediatr Crit Care Med. 2019 Jul;20(7):e352-e361. doi: 10.1097/PCC.0000000000001968.

PMID:
31149967
9.

Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery.

O'Brien CE, Santos PT, Kulikowicz E, Reyes M, Koehler RC, Martin LJ, Lee JK.

Dev Neurosci. 2019;41(1-2):17-33. doi: 10.1159/000496602. Epub 2019 May 20.

10.

Comparison of Frequency- and Time-Domain Autoregulation and Vasoreactivity Indices in a Piglet Model of Hypoxia-Ischemia and Hypothermia.

Govindan RB, Brady KM, Massaro AN, Perin J, Jennings JM, DuPlessis AJ, Koehler RC, Lee JK.

Dev Neurosci. 2019 May 2:1-13. doi: 10.1159/000499425. [Epub ahead of print]

11.

Spatial T-maze identifies cognitive deficits in piglets 1 month after hypoxia-ischemia in a model of hippocampal pyramidal neuron loss and interneuron attrition.

Singh R, Kulikowicz E, Santos PT, Koehler RC, Martin LJ, Lee JK.

Behav Brain Res. 2019 Sep 2;369:111921. doi: 10.1016/j.bbr.2019.111921. Epub 2019 Apr 19.

PMID:
31009645
12.

Pathophysiological Insights into Spreading Depolarization in Severe Traumatic Brain Injury.

Stevens RD, Koehler RC.

Neurocrit Care. 2019 Jun;30(3):569-571. doi: 10.1007/s12028-019-00705-8. No abstract available.

PMID:
30877553
13.

Biodistribution of Glial Progenitors in a Three Dimensional-Printed Model of the Piglet Cerebral Ventricular System.

Srivastava RK, Jablonska A, Chu C, Gregg L, Bulte JWM, Koehler RC, Walczak P, Janowski M.

Stem Cells Dev. 2019 Apr 15;28(8):515-527. doi: 10.1089/scd.2018.0172. Epub 2019 Mar 28.

PMID:
30760110
14.

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.

Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM, Harrison CJ, Moorman AV, Vora A, Roman E, Rachakonda S, Kinsey SE, Sheridan E, Thompson PD, Irving JA, Koehler R, Hoffmann P, Nöthen MM, Heilmann-Heimbach S, Jöckel KH, Easton DF, Pharaoh PDP, Dunning AM, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N; PRACTICAL consortium, Greaves M, Zimmerman M, Bartram CR, Schrappe M, Stanulla M, Hemminki K, Houlston RS.

Nat Commun. 2019 Jan 21;10(1):419. doi: 10.1038/s41467-018-08106-9.

15.

Pilot Study to Compare the Use of End-Tidal Carbon Dioxide-Guided and Diastolic Blood Pressure-Guided Chest Compression Delivery in a Swine Model of Neonatal Asphyxial Cardiac Arrest.

O'Brien CE, Reyes M, Santos PT, Heitmiller SE, Kulikowicz E, Kudchadkar SR, Lee JK, Hunt EA, Koehler RC, Shaffner DH.

J Am Heart Assoc. 2018 Oct 2;7(19):e009728. doi: 10.1161/JAHA.118.009728.

16.

Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets.

Santos PT, O'Brien CE, Chen MW, Hopkins CD, Adams S, Kulikowicz E, Singh R, Koehler RC, Martin LJ, Lee JK.

J Am Heart Assoc. 2018 Oct 16;7(20):e009415. doi: 10.1161/JAHA.118.009415.

17.

Perinatal hypoxic-ischemic brain injury in large animal models: Relevance to human neonatal encephalopathy.

Koehler RC, Yang ZJ, Lee JK, Martin LJ.

J Cereb Blood Flow Metab. 2018 Dec;38(12):2092-2111. doi: 10.1177/0271678X18797328. Epub 2018 Aug 28. Review.

18.

The contribution of TRPV1 channel to 20-HETE-Aggravated ischemic neuronal injury.

Zhang X, El Demerdash N, Falck JR, Munnuri S, Koehler RC, Yang ZJ.

Prostaglandins Other Lipid Mediat. 2018 Jul;137:63-68. doi: 10.1016/j.prostaglandins.2018.07.001. Epub 2018 Jul 6. Review.

19.

Traumatic Injury Leads to Inflammation and Altered Tryptophan Metabolism in the Juvenile Rabbit Brain.

Zhang Z, Rasmussen L, Saraswati M, Koehler RC, Robertson C, Kannan S.

J Neurotrauma. 2018 Sep 11. doi: 10.1089/neu.2017.5450. [Epub ahead of print]

PMID:
30019623
20.

Refinement of embolic stroke model in rats: Effect of post-embolization anesthesia duration on arterial blood pressure, cerebral edema and mortality.

Chuang BTC, Liu X, Lundberg AJ, Toung TJK, Ulatowski JA, Koehler RC.

J Neurosci Methods. 2018 Sep 1;307:8-13. doi: 10.1016/j.jneumeth.2018.06.012. Epub 2018 Jun 20.

21.

Validation of noninvasive photoacoustic measurements of sagittal sinus oxyhemoglobin saturation in hypoxic neonatal piglets.

Kang J, Boctor EM, Adams S, Kulikowicz E, Zhang HK, Koehler RC, Graham EM.

J Appl Physiol (1985). 2018 Oct 1;125(4):983-989. doi: 10.1152/japplphysiol.00184.2018. Epub 2018 Jun 21.

22.

Therapeutic hypothermia promotes cerebral blood flow recovery and brain homeostasis after resuscitation from cardiac arrest in a rat model.

Wang Q, Miao P, Modi HR, Garikapati S, Koehler RC, Thakor NV.

J Cereb Blood Flow Metab. 2019 Oct;39(10):1961-1973. doi: 10.1177/0271678X18773702. Epub 2018 May 9.

PMID:
29739265
23.

A systematic review of opioid use after extremity trauma in orthopedic surgery.

Koehler RM, Okoroafor UC, Cannada LK.

Injury. 2018 Jun;49(6):1003-1007. doi: 10.1016/j.injury.2018.04.003. Epub 2018 Apr 12.

PMID:
29704954
24.

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.

Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM, Harrison CJ, Moorman AV, Vora A, Roman E, Rachakonda S, Kinsey SE, Sheridan E, Thompson PD, Irving JA, Koehler R, Hoffmann P, Nöthen MM, Heilmann-Heimbach S, Jöckel KH, Easton DF, Pharaoh PDP, Dunning AM, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N; PRACTICAL Consortium, Greaves M, Zimmerman M, Bartram CR, Schrappe M, Stanulla M, Hemminki K, Houlston RS.

Nat Commun. 2018 Apr 9;9(1):1340. doi: 10.1038/s41467-018-03178-z. Erratum in: Nat Commun. 2019 Jan 21;10(1):419.

25.

Cerebral Autoregulation and Conventional and Diffusion Tensor Imaging Magnetic Resonance Imaging in Neonatal Hypoxic-Ischemic Encephalopathy.

Carrasco M, Perin J, Jennings JM, Parkinson C, Gilmore MM, Chavez-Valdez R, Massaro AN, Koehler RC, Northington FJ, Tekes A, Lee JK.

Pediatr Neurol. 2018 May;82:36-43. doi: 10.1016/j.pediatrneurol.2018.02.004. Epub 2018 Apr 2.

26.

Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia.

Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC.

Sci Rep. 2018 Mar 27;8(1):5279. doi: 10.1038/s41598-018-23504-1.

27.

Abdominal near-infrared spectroscopy in a piglet model of gastrointestinal hypoxia produced by graded hypoxia or superior mesenteric artery ligation.

Chen MW, Reyes M, Kulikowicz E, Martin L, Hackam DJ, Koehler RC, Lee JK.

Pediatr Res. 2018 Jun;83(6):1172-1181. doi: 10.1038/pr.2018.37. Epub 2018 May 2.

28.

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.

Stanulla M, Dagdan E, Zaliova M, Möricke A, Palmi C, Cazzaniga G, Eckert C, Te Kronnie G, Bourquin JP, Bornhauser B, Koehler R, Bartram CR, Ludwig WD, Bleckmann K, Groeneveld-Krentz S, Schewe D, Junk SV, Hinze L, Klein N, Kratz CP, Biondi A, Borkhardt A, Kulozik A, Muckenthaler MU, Basso G, Valsecchi MG, Izraeli S, Petersen BS, Franke A, Dörge P, Steinemann D, Haas OA, Panzer-Grümayer R, Cavé H, Houlston RS, Cario G, Schrappe M, Zimmermann M; TRANSCALL Consortium; International BFM Study Group.

J Clin Oncol. 2018 Apr 20;36(12):1240-1249. doi: 10.1200/JCO.2017.74.3617. Epub 2018 Mar 2.

PMID:
29498923
29.

20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis.

Han X, Zhao X, Lan X, Li Q, Gao Y, Liu X, Wan J, Yang Z, Chen X, Zang W, Guo AM, Falck JR, Koehler RC, Wang J.

J Cereb Blood Flow Metab. 2019 Aug;39(8):1531-1543. doi: 10.1177/0271678X18762645. Epub 2018 Feb 27.

PMID:
29485354
30.

A robust targeted sequencing approach for low input and variable quality DNA from clinical samples.

So AP, Vilborg A, Bouhlal Y, Koehler RT, Grimes SM, Pouliot Y, Mendoza D, Ziegle J, Stein J, Goodsaid F, Lucero MY, De La Vega FM, Ji HP.

NPJ Genom Med. 2018 Jan 15;3:2. doi: 10.1038/s41525-017-0041-4. eCollection 2018.

31.

Anti-reflux procedures: complications, radiologic findings, and surgical and gastroenterologic perspectives.

Zarzour JG, Morgan DE, Callaway JP, Hawn MT, Canon CL, Koehler RE.

Abdom Radiol (NY). 2018 Jun;43(6):1308-1318. doi: 10.1007/s00261-017-1446-3. Review.

PMID:
29302737
32.

Surgical Smoke Simulation Study: Physical Characterization and Respiratory Protection.

Elmashae Y, Koehler RH, Yermakov M, Reponen T, Grinshpun SA.

Aerosol Sci Technol. 2018;52(1):38-45. doi: 10.1080/02786826.2017.1373180. Epub 2017 Sep 29.

33.

Transfusion of Polynitroxylated Pegylated Hemoglobin Stabilizes Pial Arterial Dilation and Decreases Infarct Volume After Transient Middle Cerebral Artery Occlusion.

Cao S, Zhang J, Ma L, Hsia CJC, Koehler RC.

J Am Heart Assoc. 2017 Sep 12;6(9). pii: e006505. doi: 10.1161/JAHA.117.006505.

34.

Inhibition of tPA-induced hemorrhagic transformation involves adenosine A2b receptor activation after cerebral ischemia.

Li Q, Han X, Lan X, Hong X, Li Q, Gao Y, Luo T, Yang Q, Koehler RC, Zhai Y, Zhou J, Wang J.

Neurobiol Dis. 2017 Dec;108:173-182. doi: 10.1016/j.nbd.2017.08.011. Epub 2017 Aug 19.

35.

End-Tidal CO2-Guided Chest Compression Delivery Improves Survival in a Neonatal Asphyxial Cardiac Arrest Model.

Hamrick JT, Hamrick JL, Bhalala U, Armstrong JS, Lee JH, Kulikowicz E, Lee JK, Kudchadkar SR, Koehler RC, Hunt EA, Shaffner DH.

Pediatr Crit Care Med. 2017 Nov;18(11):e575-e584. doi: 10.1097/PCC.0000000000001299.

36.

Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy.

Cui D, Sun D, Wang X, Yi L, Kulikowicz E, Reyes M, Zhu J, Yang ZJ, Jiang W, Koehler RC.

Cell Death Dis. 2017 Jul 13;8(7):e2919. doi: 10.1038/cddis.2017.318.

37.

Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.

Annamalai K, Liberta F, Vielberg MT, Close W, Lilie H, Gührs KH, Schierhorn A, Koehler R, Schmidt A, Haupt C, Hegenbart U, Schönland S, Schmidt M, Groll M, Fändrich M.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7510-7514. doi: 10.1002/anie.201701761. Epub 2017 May 23.

PMID:
28544119
38.

Inhibition of neuronal ferroptosis protects hemorrhagic brain.

Li Q, Han X, Lan X, Gao Y, Wan J, Durham F, Cheng T, Yang J, Wang Z, Jiang C, Ying M, Koehler RC, Stockwell BR, Wang J.

JCI Insight. 2017 Apr 6;2(7):e90777. doi: 10.1172/jci.insight.90777.

39.

Upregulation of 20-HETE Synthetic Cytochrome P450 Isoforms by Oxygen-Glucose Deprivation in Cortical Neurons.

Zhang H, Falck JR, Roman RJ, Harder DR, Koehler RC, Yang ZJ.

Cell Mol Neurobiol. 2017 Oct;37(7):1279-1286. doi: 10.1007/s10571-017-0462-8. Epub 2017 Jan 21.

40.

Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation.

Zhang Y, Hong G, Lee KS, Hammock BD, Gebremedhin D, Harder DR, Koehler RC, Sapirstein A.

J Neurochem. 2017 Mar;140(5):814-825. doi: 10.1111/jnc.13933. Epub 2017 Jan 23.

41.

Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury.

Lee JK, Poretti A, Perin J, Huisman TAGM, Parkinson C, Chavez-Valdez R, O'Connor M, Reyes M, Armstrong J, Jennings JM, Gilmore MM, Koehler RC, Northington FJ, Tekes A.

Dev Neurosci. 2017;39(1-4):248-256. doi: 10.1159/000452833. Epub 2016 Dec 16.

42.

Combined scanning probe microscopy and x-ray scattering instrument for in situ catalysis investigations.

Onderwaater WG, van der Tuijn PC, Mom RV, van Spronsen MA, Roobol SB, Saedi A, Drnec J, Isern H, Carla F, Dufrane T, Koehler R, Crama B, Groot IM, Felici R, Frenken JW.

Rev Sci Instrum. 2016 Nov;87(11):113705.

PMID:
27910601
43.

18F-FNDP for PET Imaging of Soluble Epoxide Hydrolase.

Horti AG, Wang Y, Minn I, Lan X, Wang J, Koehler RC, Alkayed NJ, Dannals RF, Pomper MG.

J Nucl Med. 2016 Nov;57(11):1817-1822. Epub 2016 Jul 14.

44.

A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1.

Vijayakrishnan J, Kumar R, Henrion MY, Moorman AV, Rachakonda PS, Hosen I, da Silva Filho MI, Holroyd A, Dobbins SE, Koehler R, Thomsen H, Irving JA, Allan JM, Lightfoot T, Roman E, Kinsey SE, Sheridan E, Thompson PD, Hoffmann P, Nöthen MM, Heilmann-Heimbach S, Jöckel KH, Greaves M, Harrison CJ, Bartram CR, Schrappe M, Stanulla M, Hemminki K, Houlston RS.

Leukemia. 2017 Mar;31(3):573-579. doi: 10.1038/leu.2016.271. Epub 2016 Oct 3.

45.

Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets.

Lee JK, Wang B, Reyes M, Armstrong JS, Kulikowicz E, Santos PT, Lee JH, Koehler RC, Martin LJ.

Dev Neurosci. 2016;38(4):277-294. Epub 2016 Sep 14.

46.

Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis.

Zhang J, Li X, Kwansa H, Kim YT, Yi L, Hong G, Andrabi SA, Dawson VL, Dawson TM, Koehler RC, Yang ZJ.

J Cereb Blood Flow Metab. 2017 Jun;37(6):1982-1993. doi: 10.1177/0271678X16658491. Epub 2016 Jan 1.

47.

Polymorphism of Amyloid Fibrils In Vivo.

Annamalai K, Gührs KH, Koehler R, Schmidt M, Michel H, Loos C, Gaffney PM, Sigurdson CJ, Hegenbart U, Schönland S, Fändrich M.

Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4822-5. doi: 10.1002/anie.201511524. Epub 2016 Mar 8.

48.

Pediatric Traumatic Brain Injury: Is It Time to Consider Gender-Based Treatments?

Lee JK, Koehler RC.

Pediatr Crit Care Med. 2016 Mar;17(3):275-6. doi: 10.1097/PCC.0000000000000604. No abstract available.

49.

Performance of Facepiece Respirators and Surgical Masks Against Surgical Smoke: Simulated Workplace Protection Factor Study.

Gao S, Koehler RH, Yermakov M, Grinshpun SA.

Ann Occup Hyg. 2016 Jun;60(5):608-18. doi: 10.1093/annhyg/mew006. Epub 2016 Feb 28.

PMID:
26929204
50.

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia.

Zuna J, Moericke A, Arens M, Koehler R, Panzer-Grümayer R, Bartram CR, Fischer S, Fronkova E, Zaliova M, Schrauder A, Stanulla M, Zimmermann M, Trka J, Stary J, Attarbaschi A, Mann G, Schrappe M, Cario G.

Br J Haematol. 2016 Jun;173(5):742-8. doi: 10.1111/bjh.13989. Epub 2016 Feb 23.

PMID:
26913693

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