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Items: 1 to 50 of 87

1.

Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.

Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB.

Nature. 2020 Jan;577(7791):E7. doi: 10.1038/s41586-019-1890-z.

PMID:
31896820
2.

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.

Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB.

Nature. 2019 Nov;575(7782):380-384. doi: 10.1038/s41586-019-1715-0. Epub 2019 Oct 30. Erratum in: Nature. 2020 Jan;577(7791):E7.

PMID:
31666695
3.

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.

Yien YY, Shi J, Chen C, Cheung JTM, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon LI, Palis J, Burke MD, Bauer DE, Orkin SH, Koehler CM, Phillips JD, Kaplan J, Ward DM, Lodish HF, Paw BH.

J Biol Chem. 2018 Dec 21;293(51):19797-19811. doi: 10.1074/jbc.RA118.002742. Epub 2018 Oct 26.

4.

PNPase knockout results in mtDNA loss and an altered metabolic gene expression program.

Shimada E, Ahsan FM, Nili M, Huang D, Atamdede S, TeSlaa T, Case D, Yu X, Gregory BD, Perrin BJ, Koehler CM, Teitell MA.

PLoS One. 2018 Jul 19;13(7):e0200925. doi: 10.1371/journal.pone.0200925. eCollection 2018.

5.

ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release.

Steffen J, Koehler CM.

J Cell Biol. 2018 Jan 2;217(1):15-17. doi: 10.1083/jcb.201711075. Epub 2017 Dec 19.

6.

Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import.

Filipuzzi I, Steffen J, Germain M, Goepfert L, Conti MA, Potting C, Cerino R, Pfeifer M, Krastel P, Hoepfner D, Bastien J, Koehler CM, Helliwell SB.

Nat Chem Biol. 2017 Dec;13(12):1239-1244. doi: 10.1038/nchembio.2493. Epub 2017 Oct 9.

7.

Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space.

Neal SE, Dabir DV, Wijaya J, Boon C, Koehler CM.

Mol Biol Cell. 2017 Oct 15;28(21):2773-2785. doi: 10.1091/mbc.E16-10-0712. Epub 2017 Aug 16.

8.

Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).

Sangwan S, Zhao A, Adams KL, Jayson CK, Sawaya MR, Guenther EL, Pan AC, Ngo J, Moore DM, Soriaga AB, Do TD, Goldschmidt L, Nelson R, Bowers MT, Koehler CM, Shaw DE, Novitch BG, Eisenberg DS.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):8770-8775. doi: 10.1073/pnas.1705091114. Epub 2017 Jul 31.

9.

Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44.

Miyata N, Tang Z, Conti MA, Johnson ME, Douglas CJ, Hasson SA, Damoiseaux R, Chang CA, Koehler CM.

J Biol Chem. 2017 Mar 31;292(13):5429-5442. doi: 10.1074/jbc.M116.770131. Epub 2017 Feb 6.

10.

Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway.

Thangamani S, Maland M, Mohammad H, Pascuzzi PE, Avramova L, Koehler CM, Hazbun TR, Seleem MN.

Front Cell Infect Microbiol. 2017 Jan 18;7:4. doi: 10.3389/fcimb.2017.00004. eCollection 2017.

11.

Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria.

Steffen J, Vashisht AA, Wan J, Jen JC, Claypool SM, Wohlschlegel JA, Koehler CM.

Mol Biol Cell. 2017 Mar 1;28(5):600-612. doi: 10.1091/mbc.E16-07-0545. Epub 2017 Jan 5.

12.

Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia.

Wan J, Steffen J, Yourshaw M, Mamsa H, Andersen E, Rudnik-Schöneborn S, Pope K, Howell KB, McLean CA, Kornberg AJ, Joseph J, Lockhart PJ, Zerres K, Ryan MM, Nelson SF, Koehler CM, Jen JC.

Brain. 2016 Nov 1;139(11):2877-2890. doi: 10.1093/brain/aww212.

13.

Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells.

Wu TH, Sagullo E, Case D, Zheng X, Li Y, Hong JS, TeSlaa T, Patananan AN, McCaffery JM, Niazi K, Braas D, Koehler CM, Graeber TG, Chiou PY, Teitell MA.

Cell Metab. 2016 May 10;23(5):921-9. doi: 10.1016/j.cmet.2016.04.007.

14.

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA.

EMBO J. 2016 Apr 15;35(8):899. doi: 10.15252/embj.201694054. No abstract available.

15.

Defining functional classes of Barth syndrome mutation in humans.

Lu YW, Galbraith L, Herndon JD, Lu YL, Pras-Raves M, Vervaart M, Van Kampen A, Luyf A, Koehler CM, McCaffery JM, Gottlieb E, Vaz FM, Claypool SM.

Hum Mol Genet. 2016 May 1;25(9):1754-70. doi: 10.1093/hmg/ddw046. Epub 2016 Feb 16.

16.

P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells.

Setoguchi K, TeSlaa T, Koehler CM, Teitell MA.

J Mol Biol. 2016 Apr 10;428(7):1465-75. doi: 10.1016/j.jmb.2015.07.019. Epub 2015 Jul 31.

17.

Mia40 Protein Serves as an Electron Sink in the Mia40-Erv1 Import Pathway.

Neal SE, Dabir DV, Tienson HL, Horn DM, Glaeser K, Ogozalek Loo RR, Barrientos A, Koehler CM.

J Biol Chem. 2015 Aug 21;290(34):20804-14. doi: 10.1074/jbc.M115.669440. Epub 2015 Jun 17.

18.

Mitochondria-targeted RNA import.

Wang G, Shimada E, Nili M, Koehler CM, Teitell MA.

Methods Mol Biol. 2015;1264:107-16. doi: 10.1007/978-1-4939-2257-4_11.

19.

The great escape: Mgr2 of the mitochondrial TIM23 translocon is a gatekeeper Tasked with releasing membrane proteins.

Steffen J, Koehler CM.

Mol Cell. 2014 Dec 4;56(5):613-4. doi: 10.1016/j.molcel.2014.11.022.

20.

Defining the role of oxygen tension in human neural progenitor fate.

Xie Y, Zhang J, Lin Y, Gaeta X, Meng X, Wisidagama DR, Cinkornpumin J, Koehler CM, Malone CS, Teitell MA, Lowry WE.

Stem Cell Reports. 2014 Nov 11;3(5):743-57. doi: 10.1016/j.stemcr.2014.09.021. Epub 2014 Oct 30.

21.

Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1.

Miyata N, Steffen J, Johnson ME, Fargue S, Danpure CJ, Koehler CM.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14406-11. doi: 10.1073/pnas.1408401111. Epub 2014 Sep 18.

22.

TMEM14C is required for erythroid mitochondrial heme metabolism.

Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, Kingsley PD, Garone C, Hattangadi SM, Huang H, Chen W, Keenan EM, Shah DI, Schlaeger TM, DiMauro S, Orkin SH, Cantor AB, Palis J, Koehler CM, Lodish HF, Kaplan J, Ward DM, Dailey HA, Phillips JD, Peters LL, Paw BH.

J Clin Invest. 2014 Oct;124(10):4294-304. doi: 10.1172/JCI76979. Epub 2014 Aug 26.

23.

Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.

Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE Jr, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH.

Am J Hum Genet. 2013 Nov 7;93(5):906-14. doi: 10.1016/j.ajhg.2013.09.011. Epub 2013 Oct 10.

24.

The Taz1p transacylase is imported and sorted into the outer mitochondrial membrane via a membrane anchor domain.

Herndon JD, Claypool SM, Koehler CM.

Eukaryot Cell. 2013 Dec;12(12):1600-8. doi: 10.1128/EC.00237-13. Epub 2013 Sep 27.

25.

A small molecule inhibitor of redox-regulated protein translocation into mitochondria.

Dabir DV, Hasson SA, Setoguchi K, Johnson ME, Wongkongkathep P, Douglas CJ, Zimmerman J, Damoiseaux R, Teitell MA, Koehler CM.

Dev Cell. 2013 Apr 15;25(1):81-92. doi: 10.1016/j.devcel.2013.03.006.

26.

Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal.

Zhang J, Nuebel E, Daley GQ, Koehler CM, Teitell MA.

Cell Stem Cell. 2012 Nov 2;11(5):589-95. doi: 10.1016/j.stem.2012.10.005.

27.

A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss.

von Ameln S, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C.

Am J Hum Genet. 2012 Nov 2;91(5):919-27. doi: 10.1016/j.ajhg.2012.09.002. Epub 2012 Oct 18.

28.

Role of twin Cys-Xaa9-Cys motif cysteines in mitochondrial import of the cytochrome C oxidase biogenesis factor Cmc1.

Bourens M, Dabir DV, Tienson HL, Sorokina I, Koehler CM, Barrientos A.

J Biol Chem. 2012 Sep 7;287(37):31258-69. doi: 10.1074/jbc.M112.383562. Epub 2012 Jul 5.

29.

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells.

Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA.

Nat Protoc. 2012 May 10;7(6):1068-85. doi: 10.1038/nprot.2012.048.

30.

Correcting human mitochondrial mutations with targeted RNA import.

Wang G, Shimada E, Zhang J, Hong JS, Smith GM, Teitell MA, Koehler CM.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4840-5. doi: 10.1073/pnas.1116792109. Epub 2012 Mar 12.

31.

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA.

EMBO J. 2011 Nov 15;30(24):4860-73. doi: 10.1038/emboj.2011.401. Erratum in: EMBO J. 2016 Apr 15;35(8):899.

32.

PNPASE and RNA trafficking into mitochondria.

Wang G, Shimada E, Koehler CM, Teitell MA.

Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):998-1007. doi: 10.1016/j.bbagrm.2011.10.001. Epub 2011 Oct 13. Review.

33.

The complexity of cardiolipin in health and disease.

Claypool SM, Koehler CM.

Trends Biochem Sci. 2012 Jan;37(1):32-41. doi: 10.1016/j.tibs.2011.09.003. Epub 2011 Oct 17. Review.

34.

Barth syndrome mutations that cause tafazzin complex lability.

Claypool SM, Whited K, Srijumnong S, Han X, Koehler CM.

J Cell Biol. 2011 Feb 7;192(3):447-62. doi: 10.1083/jcb.201008177.

35.

PNPASE regulates RNA import into mitochondria.

Wang G, Chen HW, Oktay Y, Zhang J, Allen EL, Smith GM, Fan KC, Hong JS, French SW, McCaffery JM, Lightowlers RN, Morse HC 3rd, Koehler CM, Teitell MA.

Cell. 2010 Aug 6;142(3):456-67. doi: 10.1016/j.cell.2010.06.035.

36.

The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model.

Curado S, Ober EA, Walsh S, Cortes-Hernandez P, Verkade H, Koehler CM, Stainier DY.

Dis Model Mech. 2010 Jul-Aug;3(7-8):486-95. doi: 10.1242/dmm.004390. Epub 2010 May 18.

37.

Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation.

Hasson SA, Damoiseaux R, Glavin JD, Dabir DV, Walker SS, Koehler CM.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9578-83. doi: 10.1073/pnas.0914387107. Epub 2010 May 10.

38.

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.

Zaltsman Y, Shachnai L, Yivgi-Ohana N, Schwarz M, Maryanovich M, Houtkooper RH, Vaz FM, De Leonardis F, Fiermonte G, Palmieri F, Gillissen B, Daniel PT, Jimenez E, Walsh S, Koehler CM, Roy SS, Walter L, Hajnóczky G, Gross A.

Nat Cell Biol. 2010 Jun;12(6):553-562. doi: 10.1038/ncb2057. Epub 2010 May 2.

39.

Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria.

Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon LA, Schon EA.

Am J Pathol. 2009 Nov;175(5):1810-6. doi: 10.2353/ajpath.2009.090219. Epub 2009 Oct 15.

40.

Importing mitochondrial proteins: machineries and mechanisms.

Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N.

Cell. 2009 Aug 21;138(4):628-44. doi: 10.1016/j.cell.2009.08.005. Review.

41.

Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.

Tienson HL, Dabir DV, Neal SE, Loo R, Hasson SA, Boontheung P, Kim SK, Loo JA, Koehler CM.

Mol Biol Cell. 2009 Aug;20(15):3481-90. doi: 10.1091/mbc.E08-10-1062. Epub 2009 May 28.

42.

Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation.

Lu G, Sun H, Korge P, Koehler CM, Weiss JN, Wang Y.

Methods Enzymol. 2009;457:255-73. doi: 10.1016/S0076-6879(09)05014-9.

43.

The cardiolipin transacylase, tafazzin, associates with two distinct respiratory components providing insight into Barth syndrome.

Claypool SM, Boontheung P, McCaffery JM, Loo JA, Koehler CM.

Mol Biol Cell. 2008 Dec;19(12):5143-55. doi: 10.1091/mbc.E08-09-0896. Epub 2008 Sep 17. Erratum in: Mol Biol Cell. 2012 Jul;23(13):2619.

44.

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane.

Claypool SM, Oktay Y, Boontheung P, Loo JA, Koehler CM.

J Cell Biol. 2008 Sep 8;182(5):937-50. doi: 10.1083/jcb.200801152. Erratum in: J Cell Biol. 2012 Jun 25;197(7):1029.

45.

Redox regulation of protein folding in the mitochondrial intermembrane space.

Koehler CM, Tienson HL.

Biochim Biophys Acta. 2009 Jan;1793(1):139-45. doi: 10.1016/j.bbamcr.2008.08.002. Epub 2008 Aug 13. Review.

46.

The Tim8-Tim13 complex has multiple substrate binding sites and binds cooperatively to Tim23.

Beverly KN, Sawaya MR, Schmid E, Koehler CM.

J Mol Biol. 2008 Oct 24;382(5):1144-56. doi: 10.1016/j.jmb.2008.07.069. Epub 2008 Jul 30.

47.

Gazing at translocation in the mitochondrion.

Walsh S, Koehler CM.

Cell. 2008 Aug 8;134(3):382-3. doi: 10.1016/j.cell.2008.07.024.

48.

Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase.

Gebert N, Chacinska A, Wagner K, Guiard B, Koehler CM, Rehling P, Pfanner N, Wiedemann N.

EMBO Rep. 2008 Jun;9(6):548-54. doi: 10.1038/embor.2008.49. Epub 2008 Apr 18.

49.

In vitro analysis of yeast mitochondrial protein import.

Stuart RA, Koehler CM.

Curr Protoc Cell Biol. 2007 Mar;Chapter 11:Unit 11.19. doi: 10.1002/0471143030.cb1119s34.

PMID:
18228496
50.

Human polynucleotide phosphorylase: location matters.

Chen HW, Koehler CM, Teitell MA.

Trends Cell Biol. 2007 Dec;17(12):600-8. Epub 2007 Nov 5. Review.

PMID:
17983748

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