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Items: 1 to 50 of 233

1.

Molecular Mimicry of SecA and Signal Recognition Particle Binding to the Bacterial Ribosome.

Knüpffer L, Fehrenbach C, Denks K, Erichsen V, Petriman NA, Koch HG.

MBio. 2019 Aug 13;10(4). pii: e01317-19. doi: 10.1128/mBio.01317-19.

2.

Challenges to building and maintaining partnership in the prevention and treatment of pressure injuries in spinal cord injury: a qualitative study of health professionals' views.

Zanini C, Rubinelli S, Lustenberger N, Koch HG, Scheel-Sailer A, Brach M.

Swiss Med Wkly. 2019 Jun 30;149:w20086. doi: 10.4414/smw.2019.20086. eCollection 2019 Jun 17.

3.

Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood.

Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rübsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hübner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, von Koch FE, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Röhrig E, Karch A, Mikolajczyk R.

Int J Epidemiol. 2019 Apr 1. pii: dyz069. doi: 10.1093/ije/dyz069. [Epub ahead of print] No abstract available.

PMID:
30938437
4.

Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood.

Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rübsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hübner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, Edler von Koch F, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Röhrig E, Mikolajczyk R.

Int J Epidemiol. 2019 Feb 27. pii: dyz001. doi: 10.1093/ije/dyz001. [Epub ahead of print] No abstract available.

PMID:
30815674
5.

Cu Transport by the Extended Family of CcoA-like Transporters (CalT) in Proteobacteria.

Zhang Y, Blaby-Haas CE, Steimle S, Verissimo AF, Garcia-Angulo VA, Koch HG, Daldal F, Khalfaoui-Hassani B.

Sci Rep. 2019 Feb 4;9(1):1208. doi: 10.1038/s41598-018-37988-4.

6.

The Cu chaperone CopZ is required for Cu homeostasis in Rhodobacter capsulatus and influences cytochrome cbb3 oxidase assembly.

Utz M, Andrei A, Milanov M, Trasnea PI, Marckmann D, Daldal F, Koch HG.

Mol Microbiol. 2019 Mar;111(3):764-783. doi: 10.1111/mmi.14190. Epub 2019 Jan 31.

PMID:
30582886
7.

Engaging in the prevention of pressure injuries in spinal cord injury: A qualitative study of community-dwelling individuals' different styles of prevention in Switzerland.

Zanini C, Brach M, Lustenberger N, Scheel-Sailer A, Koch HG, Stucki G, Rubinelli S.

J Spinal Cord Med. 2018 Dec 12:1-10. doi: 10.1080/10790268.2018.1543094. [Epub ahead of print]

PMID:
30540555
8.

Residential location of people with chronic spinal cord injury: the importance of local health care infrastructure.

Ronca E, Brunkert T, Koch HG, Jordan X, Gemperli A.

BMC Health Serv Res. 2018 Aug 22;18(1):657. doi: 10.1186/s12913-018-3449-3.

9.

Increased differentiation and production of extracellular matrix components of primary human osteoblasts after cocultivation with endothelial cells: A quantitative proteomics approach.

Simunovic F, Winninger O, Strassburg S, Koch HG, Finkenzeller G, Stark GB, Lampert FM.

J Cell Biochem. 2019 Jan;120(1):396-404. doi: 10.1002/jcb.27394. Epub 2018 Aug 20.

PMID:
30126049
10.

Satisfaction with access and quality of healthcare services for people with spinal cord injury living in the community.

Ronca E, Scheel-Sailer A, Koch HG, Essig S, Brach M, Münzel N, Gemperli A; SwiSCI Study Group.

J Spinal Cord Med. 2018 Jul 2:1-11. doi: 10.1080/10790268.2018.1486623. [Epub ahead of print]

PMID:
29965779
11.

Co-translational protein targeting in bacteria.

Steinberg R, Knüpffer L, Origi A, Asti R, Koch HG.

FEMS Microbiol Lett. 2018 Jun 1;365(11). doi: 10.1093/femsle/fny095. Review.

PMID:
29790984
12.

A Copper Relay System Involving Two Periplasmic Chaperones Drives cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus.

Trasnea PI, Andrei A, Marckmann D, Utz M, Khalfaoui-Hassani B, Selamoglu N, Daldal F, Koch HG.

ACS Chem Biol. 2018 May 18;13(5):1388-1397. doi: 10.1021/acschembio.8b00293. Epub 2018 Apr 9.

13.

Widespread Distribution and Functional Specificity of the Copper Importer CcoA: Distinct Cu Uptake Routes for Bacterial Cytochrome c Oxidases.

Khalfaoui-Hassani B, Wu H, Blaby-Haas CE, Zhang Y, Sandri F, Verissimo AF, Koch HG, Daldal F.

MBio. 2018 Feb 27;9(1). pii: e00065-18. doi: 10.1128/mBio.00065-18.

14.

The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY.

Petriman NA, Jauß B, Hufnagel A, Franz L, Sachelaru I, Drepper F, Warscheid B, Koch HG.

Sci Rep. 2018 Jan 12;8(1):578. doi: 10.1038/s41598-017-19019-w.

15.

Absence of Thiol-Disulfide Oxidoreductase DsbA Impairs cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus.

Onder O, Verissimo AF, Khalfaoui-Hassani B, Peters A, Koch HG, Daldal F.

Front Microbiol. 2017 Dec 21;8:2576. doi: 10.3389/fmicb.2017.02576. eCollection 2017.

16.

The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins.

Gonsberg A, Jung S, Ulbrich S, Origi A, Ziska A, Baier M, Koch HG, Zimmermann R, Winklhofer KF, Tatzelt J.

J Biol Chem. 2017 Dec 29;292(52):21383-21396. doi: 10.1074/jbc.M117.788067. Epub 2017 Oct 30.

17.

Health care utilization in persons with spinal cord injury: part 2-determinants, geographic variation and comparison with the general population.

Ronca E, Scheel-Sailer A, Koch HG, Gemperli A; SwiSCI Study Group.

Spinal Cord. 2017 Sep;55(9):828-833. doi: 10.1038/sc.2017.38. Epub 2017 May 2.

PMID:
28462934
18.

Health care utilization in persons with spinal cord injury: part 1-outpatient services.

Gemperli A, Ronca E, Scheel-Sailer A, Koch HG, Brach M, Trezzini B; SwiSCI Study Group.

Spinal Cord. 2017 Sep;55(9):823-827. doi: 10.1038/sc.2017.44. Epub 2017 May 2.

PMID:
28462932
19.

Targeting and Insertion of Membrane Proteins.

Kuhn A, Koch HG, Dalbey RE.

EcoSal Plus. 2017 Mar;7(2). doi: 10.1128/ecosalplus.ESP-0012-2016. Review.

PMID:
28276312
20.

YidC and SecYEG form a heterotetrameric protein translocation channel.

Sachelaru I, Winter L, Knyazev DG, Zimmermann M, Vogt A, Kuttner R, Ollinger N, Siligan C, Pohl P, Koch HG.

Sci Rep. 2017 Mar 7;7(1):101. doi: 10.1038/s41598-017-00109-8.

21.

The signal recognition particle contacts uL23 and scans substrate translation inside the ribosomal tunnel.

Denks K, Sliwinski N, Erichsen V, Borodkina B, Origi A, Koch HG.

Nat Microbiol. 2017 Jan 30;2:16265. doi: 10.1038/nmicrobiol.2016.265.

PMID:
28134917
22.

Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.

Braig D, Nero TL, Koch HG, Kaiser B, Wang X, Thiele JR, Morton CJ, Zeller J, Kiefer J, Potempa LA, Mellett NA, Miles LA, Du XJ, Meikle PJ, Huber-Lang M, Stark GB, Parker MW, Peter K, Eisenhardt SU.

Nat Commun. 2017 Jan 23;8:14188. doi: 10.1038/ncomms14188.

23.

Inpatient migration patterns in persons with spinal cord injury: A registry study with hospital discharge data.

Ronca E, Scheel-Sailer A, Koch HG, Metzger S, Gemperli A.

SSM Popul Health. 2016 Apr 30;2:259-268. doi: 10.1016/j.ssmph.2016.04.004. eCollection 2016 Dec.

24.

Uncovering the Transmembrane Metal Binding Site of the Novel Bacterial Major Facilitator Superfamily-Type Copper Importer CcoA.

Khalfaoui-Hassani B, Verissimo AF, Koch HG, Daldal F.

MBio. 2016 Jan 19;7(1):e01981-15. doi: 10.1128/mBio.01981-15.

25.

Cooperation between two periplasmic copper chaperones is required for full activity of the cbb3 -type cytochrome c oxidase and copper homeostasis in Rhodobacter capsulatus.

Trasnea PI, Utz M, Khalfaoui-Hassani B, Lagies S, Daldal F, Koch HG.

Mol Microbiol. 2016 Apr;100(2):345-61. doi: 10.1111/mmi.13321. Epub 2016 Feb 28.

26.

The characteristics of posttraumatic syringomyelia.

Krebs J, Koch HG, Hartmann K, Frotzler A.

Spinal Cord. 2016 Jun;54(6):463-6. doi: 10.1038/sc.2015.218. Epub 2015 Dec 1.

PMID:
26620880
27.

Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon.

Kuhn P, Draycheva A, Vogt A, Petriman NA, Sturm L, Drepper F, Warscheid B, Wintermeyer W, Koch HG.

J Cell Biol. 2015 Oct 12;211(1):91-104. doi: 10.1083/jcb.201502103.

28.

Redox Activation of the Universally Conserved ATPase YchF by Thioredoxin 1.

Hannemann L, Suppanz I, Ba Q, MacInnes K, Drepper F, Warscheid B, Koch HG.

Antioxid Redox Signal. 2016 Jan 20;24(3):141-56. doi: 10.1089/ars.2015.6272. Epub 2015 Aug 17.

29.

YidC occupies the lateral gate of the SecYEG translocon and is sequentially displaced by a nascent membrane protein.

Sachelaru I, Petriman NA, Kudva R, Kuhn P, Welte T, Knapp B, Drepper F, Warscheid B, Koch HG.

J Biol Chem. 2015 Jun 5;290(23):14492. doi: 10.1074/jbc.A112.446583. No abstract available.

30.

Age-related variation in mobility independence among wheelchair users with spinal cord injury: A cross-sectional study.

Hinrichs T, Lay V, Arnet U, Eriks-Hoogland I, Koch HG, Rantanen T, Reinhardt JD, Brinkhof MW; SwiSCI study group.

J Spinal Cord Med. 2016;39(2):180-9. doi: 10.1179/2045772315Y.0000000008. Epub 2016 Mar 8.

31.

Insights into severe 5,10-methylenetetrahydrofolate reductase deficiency: molecular genetic and enzymatic characterization of 76 patients.

Burda P, Schäfer A, Suormala T, Rummel T, Bürer C, Heuberger D, Frapolli M, Giunta C, Sokolová J, Vlášková H, Kožich V, Koch HG, Fowler B, Froese DS, Baumgartner MR.

Hum Mutat. 2015 Jun;36(6):611-21. doi: 10.1002/humu.22779. Epub 2015 Apr 27.

PMID:
25736335
32.

Dynamic interaction of the sec translocon with the chaperone PpiD.

Sachelaru I, Petriman NA, Kudva R, Koch HG.

J Biol Chem. 2014 Aug 1;289(31):21706-15. doi: 10.1074/jbc.M114.577916. Epub 2014 Jun 20.

33.

A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties.

Braig D, Kaiser B, Thiele JR, Bannasch H, Peter K, Stark GB, Koch HG, Eisenhardt SU.

Int Immunol. 2014 Aug;26(8):467-78. doi: 10.1093/intimm/dxu056. Epub 2014 May 20.

PMID:
24844702
34.

The Sec translocon mediated protein transport in prokaryotes and eukaryotes.

Denks K, Vogt A, Sachelaru I, Petriman NA, Kudva R, Koch HG.

Mol Membr Biol. 2014 Mar-May;31(2-3):58-84. doi: 10.3109/09687688.2014.907455. Review.

PMID:
24762201
35.

Intracytoplasmic copper homeostasis controls cytochrome c oxidase production.

Ekici S, Turkarslan S, Pawlik G, Dancis A, Baliga NS, Koch HG, Daldal F.

MBio. 2014 Jan 14;5(1):e01055-13. doi: 10.1128/mBio.01055-13.

36.

YidC occupies the lateral gate of the SecYEG translocon and is sequentially displaced by a nascent membrane protein.

Sachelaru I, Petriman NA, Kudva R, Kuhn P, Welte T, Knapp B, Drepper F, Warscheid B, Koch HG.

J Biol Chem. 2013 Jun 7;288(23):16295-307. doi: 10.1074/jbc.M112.446583. Epub 2013 Apr 22. Erratum in: J Biol Chem. 2015 Jun 5;290(23):14492.

37.

Protein translocation across the inner membrane of Gram-negative bacteria: the Sec and Tat dependent protein transport pathways.

Kudva R, Denks K, Kuhn P, Vogt A, Müller M, Koch HG.

Res Microbiol. 2013 Jul-Aug;164(6):505-34. doi: 10.1016/j.resmic.2013.03.016. Epub 2013 Apr 6. Review.

PMID:
23567322
38.

Propionic acidemia: clinical course and outcome in 55 pediatric and adolescent patients.

Grünert SC, Müllerleile S, De Silva L, Barth M, Walter M, Walter K, Meissner T, Lindner M, Ensenauer R, Santer R, Bodamer OA, Baumgartner MR, Brunner-Krainz M, Karall D, Haase C, Knerr I, Marquardt T, Hennermann JB, Steinfeld R, Beblo S, Koch HG, Konstantopoulou V, Scholl-Bürgi S, van Teeffelen-Heithoff A, Suormala T, Sperl W, Kraus JP, Superti-Furga A, Schwab KO, Sass JO.

Orphanet J Rare Dis. 2013 Jan 10;8:6. doi: 10.1186/1750-1172-8-6.

39.

A universally conserved ATPase regulates the oxidative stress response in Escherichia coli.

Wenk M, Ba Q, Erichsen V, MacInnes K, Wiese H, Warscheid B, Koch HG.

J Biol Chem. 2012 Dec 21;287(52):43585-98. doi: 10.1074/jbc.M112.413070. Epub 2012 Nov 8.

40.

Missense mutations in cytochrome c maturation genes provide new insights into Rhodobacter capsulatus cbb3-type cytochrome c oxidase biogenesis.

Ekici S, Jiang X, Koch HG, Daldal F.

J Bacteriol. 2013 Jan;195(2):261-9. doi: 10.1128/JB.01415-12. Epub 2012 Nov 2.

41.

The ScoI homologue SenC is a copper binding protein that interacts directly with the cbb₃-type cytochrome oxidase in Rhodobacter capsulatus.

Lohmeyer E, Schröder S, Pawlik G, Trasnea PI, Peters A, Daldal F, Koch HG.

Biochim Biophys Acta. 2012 Nov;1817(11):2005-15. doi: 10.1016/j.bbabio.2012.06.621. Epub 2012 Jul 4.

42.

Novel transporter required for biogenesis of cbb3-type cytochrome c oxidase in Rhodobacter capsulatus.

Ekici S, Yang H, Koch HG, Daldal F.

MBio. 2012 Jan 31;3(1). pii: e00293-11. doi: 10.1128/mBio.00293-11. Print 2012.

43.

A homemade MLPA assay detects known CTNS mutations and identifies a novel deletion in a previously unresolved cystinosis family.

Kiehntopf M, Varga RE, Koch HG, Beetz C.

Gene. 2012 Mar 1;495(1):89-92. doi: 10.1016/j.gene.2011.12.005. Epub 2011 Dec 24.

PMID:
22209718
44.

Promiscuous targeting of polytopic membrane proteins to SecYEG or YidC by the Escherichia coli signal recognition particle.

Welte T, Kudva R, Kuhn P, Sturm L, Braig D, Müller M, Warscheid B, Drepper F, Koch HG.

Mol Biol Cell. 2012 Feb;23(3):464-79. doi: 10.1091/mbc.E11-07-0590. Epub 2011 Dec 7.

45.

Propionic acidemia: neonatal versus selective metabolic screening.

Grünert SC, Müllerleile S, de Silva L, Barth M, Walter M, Walter K, Meissner T, Lindner M, Ensenauer R, Santer R, Bodamer OA, Baumgartner MR, Brunner-Krainz M, Karall D, Haase C, Knerr I, Marquardt T, Hennermann JB, Steinfeld R, Beblo S, Koch HG, Konstantopoulou V, Scholl-Bürgi S, van Teeffelen-Heithoff A, Suormala T, Sperl W, Kraus JP, Superti-Furga A, Schwab KO, Sass JO.

J Inherit Metab Dis. 2012 Jan;35(1):41-9. doi: 10.1007/s10545-011-9419-0. Epub 2011 Dec 2.

PMID:
22134541
46.

Biogenesis of cbb(3)-type cytochrome c oxidase in Rhodobacter capsulatus.

Ekici S, Pawlik G, Lohmeyer E, Koch HG, Daldal F.

Biochim Biophys Acta. 2012 Jun;1817(6):898-910. doi: 10.1016/j.bbabio.2011.10.011. Epub 2011 Nov 4. Review.

47.

Mutation analysis in 54 propionic acidemia patients.

Kraus JP, Spector E, Venezia S, Estes P, Chiang PW, Creadon-Swindell G, Müllerleile S, de Silva L, Barth M, Walter M, Walter K, Meissner T, Lindner M, Ensenauer R, Santer R, Bodamer OA, Baumgartner MR, Brunner-Krainz M, Karall D, Haase C, Knerr I, Marquardt T, Hennermann JB, Steinfeld R, Beblo S, Koch HG, Konstantopoulou V, Scholl-Bürgi S, van Teeffelen-Heithoff A, Suormala T, Ugarte M, Sperl W, Superti-Furga A, Schwab KO, Grünert SC, Sass JO.

J Inherit Metab Dis. 2012 Jan;35(1):51-63. doi: 10.1007/s10545-011-9399-0. Epub 2011 Oct 27.

PMID:
22033733
48.

Signal sequence-independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle.

Braig D, Mircheva M, Sachelaru I, van der Sluis EO, Sturm L, Beckmann R, Koch HG.

Mol Biol Cell. 2011 Jul 1;22(13):2309-23. doi: 10.1091/mbc.E11-02-0152. Epub 2011 May 5.

49.

The bacterial SRP receptor, SecA and the ribosome use overlapping binding sites on the SecY translocon.

Kuhn P, Weiche B, Sturm L, Sommer E, Drepper F, Warscheid B, Sourjik V, Koch HG.

Traffic. 2011 May;12(5):563-78. doi: 10.1111/j.1600-0854.2011.01167.x. Epub 2011 Feb 25.

50.

The putative assembly factor CcoH is stably associated with the cbb3-type cytochrome oxidase.

Pawlik G, Kulajta C, Sachelaru I, Schröder S, Waidner B, Hellwig P, Daldal F, Koch HG.

J Bacteriol. 2010 Dec;192(24):6378-89. doi: 10.1128/JB.00988-10. Epub 2010 Oct 15.

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