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Identification of distinctive features in human intracranial tumors by label-free nonlinear multimodal microscopy.

Galli R, Uckermann O, Sehm T, Leipnitz E, Hartmann C, Sahm F, Koch E, Schackert G, Steiner G, Kirsch M.

J Biophotonics. 2019 Jun 13:e201800465. doi: 10.1002/jbio.201800465. [Epub ahead of print]


Cebranopadol, a novel first-in-class analgesic drug candidate: first experience with cancer-related pain for up to 26 weeks.

Koch ED, Kapanadze S, Eerdekens MH, Kralidis G, Letal J, Sabatschus I, Ahmedzai SH.

J Pain Symptom Manage. 2019 May 29. pii: S0885-3924(19)30294-5. doi: 10.1016/j.jpainsymman.2019.05.012. [Epub ahead of print]


Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo.

Walther J, Li Q, Villiger M, Farah CS, Koch E, Karnowski K, Sampson DD.

Biomed Opt Express. 2019 Mar 22;10(4):1942-1956. doi: 10.1364/BOE.10.001942. eCollection 2019 Apr 1.


Sedentary behavior in everyday life relates negatively to mood: An ambulatory assessment study.

Giurgiu M, Koch ED, Ottenbacher J, Plotnikoff RC, Ebner-Priemer UW, Reichert M.

Scand J Med Sci Sports. 2019 May 2. doi: 10.1111/sms.13448. [Epub ahead of print]


Combined Sabal and Urtica Extracts (WS® 1541) Exert Anti-proliferative and Anti-inflammatory Effects in a Mouse Model of Benign Prostate Hyperplasia.

Pigat N, Reyes-Gomez E, Boutillon F, Palea S, Barry Delongchamps N, Koch E, Goffin V.

Front Pharmacol. 2019 Mar 29;10:311. doi: 10.3389/fphar.2019.00311. eCollection 2019.


Spatially Resolved Cross-Linking Characterization by Imaging Low-Coherence Interferometry.

Taudt C, Nelsen B, Rossegger E, Schlögl S, Koch E, Hartmann P.

Sensors (Basel). 2019 Mar 7;19(5). pii: E1152. doi: 10.3390/s19051152.


Transcriptome-proteome integration of archival human renal cell carcinoma biopsies enables identification of molecular mechanisms.

Koch E, Finne K, Eikrem Ø, Landolt L, Beisland C, Leh S, Delaleu N, Granly M, Vikse BE, Osman T, Scherer A, Marti HP.

Am J Physiol Renal Physiol. 2019 May 1;316(5):F1053-F1067. doi: 10.1152/ajprenal.00424.2018. Epub 2019 Mar 6.


Critical symbiont signals drive both local and systemic changes in diel and developmental host gene expression.

Moriano-Gutierrez S, Koch EJ, Bussan H, Romano K, Belcaid M, Rey FE, Ruby EG, McFall-Ngai MJ.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7990-7999. doi: 10.1073/pnas.1819897116. Epub 2019 Mar 4.


The Effects of Demography and Genetics on the Neutral Distribution of Quantitative Traits.

Koch EM.

Genetics. 2019 Apr;211(4):1371-1394. doi: 10.1534/genetics.118.301839. Epub 2019 Feb 19.


[Submacular hemorrhage with retinal detachment due to an overdose of anticoagulant during age-related macular degeneration].

Grondin C, Pascal ML, Bourdon H, Vu Q, Beaujeux P, Koch E.

J Fr Ophtalmol. 2019 Feb;42(2):215-218. doi: 10.1016/j.jfo.2018.04.019. Epub 2019 Jan 22. French. No abstract available.


Symbiotic organs shaped by distinct modes of genome evolution in cephalopods.

Belcaid M, Casaburi G, McAnulty SJ, Schmidbaur H, Suria AM, Moriano-Gutierrez S, Pankey MS, Oakley TH, Kremer N, Koch EJ, Collins AJ, Nguyen H, Lek S, Goncharenko-Foster I, Minx P, Sodergren E, Weinstock G, Rokhsar DS, McFall-Ngai M, Simakov O, Foster JS, Nyholm SV.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3030-3035. doi: 10.1073/pnas.1817322116. Epub 2019 Jan 11.


Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane.

Kirsten L, Schindler M, Morgenstern J, Erkkilä MT, Golde J, Walther J, Rottmann P, Kemper M, Bornitz M, Neudert M, Zahnert T, Koch E.

J Biomed Opt. 2018 Dec;24(3):1-11. doi: 10.1117/1.JBO.24.3.031017.


Early recognition of sepsis through emergency medical services pre-hospital screening.

Borrelli G, Koch E, Sterk E, Lovett S, Rech MA.

Am J Emerg Med. 2018 Oct 20. pii: S0735-6757(18)30850-7. doi: 10.1016/j.ajem.2018.10.036. [Epub ahead of print]


Cancer-related chronic pain: Investigation of the novel analgesic drug candidate cebranopadol in a randomized, double-blind, noninferiority trial.

Eerdekens MH, Kapanadze S, Koch ED, Kralidis G, Volkers G, Ahmedzai SH, Meissner W.

Eur J Pain. 2019 Mar;23(3):577-588. doi: 10.1002/ejp.1331. Epub 2019 Jan 9.


Direct assessment of presynaptic modulation of cortico-striatal glutamate release in a Huntington's disease mouse model.

Koch ET, Woodard CL, Raymond LA.

J Neurophysiol. 2018 Dec 1;120(6):3077-3084. doi: 10.1152/jn.00638.2018. Epub 2018 Oct 17.


Persistent Interactions with Bacterial Symbionts Direct Mature-Host Cell Morphology and Gene Expression in the Squid-Vibrio Symbiosis.

Kremer N, Koch EJ, El Filali A, Zhou L, Heath-Heckman EAC, Ruby EG, McFall-Ngai MJ.

mSystems. 2018 Oct 2;3(5). pii: e00165-18. doi: 10.1128/mSystems.00165-18. eCollection 2018 Sep-Oct.


Intraoperative mapping of the sensory cortex by time-resolved thermal imaging.

Hoffmann N, Radev Y, Koch E, Petersohn U, Steiner G, Kirsch M.

Biomed Tech (Berl). 2018 Oct 25;63(5):567-572. doi: 10.1515/bmt-2017-0229.


Fine needle aspirates of kidneys: a promising tool for RNA sequencing in native and transplanted kidneys.

Eikrem Ø, Walther TC, Flatberg A, Beisvag V, Strauss P, Farstad M, Beisland C, Koch E, Mueller TF, Marti HP.

BMC Nephrol. 2018 Sep 5;19(1):221. doi: 10.1186/s12882-018-1012-4.


Application of optical and spectroscopic technologies for the characterization of carious lesions in vitro.

Tetschke F, Kirsten L, Golde J, Walther J, Galli R, Koch E, Hannig C.

Biomed Tech (Berl). 2018 Oct 25;63(5):595-602. doi: 10.1515/bmt-2017-0133.


Blood Pressure and Heart Rate Variability in Primary Open-Angle Glaucoma and Normal Tension Glaucoma.

Lindemann F, Kuerten D, Koch E, Fuest M, Fischer C, Voss A, Plange N.

Curr Eye Res. 2018 Dec;43(12):1507-1513. doi: 10.1080/02713683.2018.1506036. Epub 2018 Aug 15.


Label-free multiphoton microscopy reveals relevant tissue changes induced by alginate hydrogel implantation in rat spinal cord injury.

Galli R, Sitoci-Ficici KH, Uckermann O, Later R, Marečková M, Koch M, Leipnitz E, Schackert G, Koch E, Gelinsky M, Steiner G, Kirsch M.

Sci Rep. 2018 Jul 18;8(1):10841. doi: 10.1038/s41598-018-29140-z.


Picture perception reveals mental geometry of 3D scene inferences.

Koch E, Baig F, Zaidi Q.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7807-7812. doi: 10.1073/pnas.1804873115. Epub 2018 Jul 9.


Cystic masses of the lateral neck - Proposition of an algorithm for increased treatment efficiency.

Koch EM, Fazel A, Hoffmann M.

J Craniomaxillofac Surg. 2018 Sep;46(9):1664-1668. doi: 10.1016/j.jcms.2018.06.004. Epub 2018 Jun 12.


IDH1 mutation in human glioma induces chemical alterations that are amenable to optical Raman spectroscopy.

Uckermann O, Yao W, Juratli TA, Galli R, Leipnitz E, Meinhardt M, Koch E, Schackert G, Steiner G, Kirsch M.

J Neurooncol. 2018 Sep;139(2):261-268. doi: 10.1007/s11060-018-2883-8. Epub 2018 May 14.


Systematic analysis of complex genetic interactions.

Kuzmin E, VanderSluis B, Wang W, Tan G, Deshpande R, Chen Y, Usaj M, Balint A, Mattiazzi Usaj M, van Leeuwen J, Koch EN, Pons C, Dagilis AJ, Pryszlak M, Wang JZY, Hanchard J, Riggi M, Xu K, Heydari H, San Luis BJ, Shuteriqi E, Zhu H, Van Dyk N, Sharifpoor S, Costanzo M, Loewith R, Caudy A, Bolnick D, Brown GW, Andrews BJ, Boone C, Myers CL.

Science. 2018 Apr 20;360(6386). pii: eaao1729. doi: 10.1126/science.aao1729.


Heel impact forces during barefoot versus minimally shod walking among Tarahumara subsistence farmers and urban Americans.

Wallace IJ, Koch E, Holowka NB, Lieberman DE.

R Soc Open Sci. 2018 Mar 14;5(3):180044. doi: 10.1098/rsos.180044. eCollection 2018 Mar.


Mood Dimensions Show Distinct Within-Subject Associations With Non-exercise Activity in Adolescents: An Ambulatory Assessment Study.

Koch ED, Tost H, Braun U, Gan G, Giurgiu M, Reinhard I, Zipf A, Meyer-Lindenberg A, Ebner-Priemer UW, Reichert M.

Front Psychol. 2018 Mar 7;9:268. doi: 10.3389/fpsyg.2018.00268. eCollection 2018.


Expanding the Utilization of Formalin-Fixed, Paraffin-Embedded Archives: Feasibility of miR-Seq for Disease Exploration and Biomarker Development from Biopsies with Clear Cell Renal Cell Carcinoma.

Strauss P, Marti HP, Beisland C, Scherer A, Lysne V, Leh S, Flatberg A, Koch E, Beisvag V, Landolt L, Skogstrand T, Eikrem Ø.

Int J Mol Sci. 2018 Mar 10;19(3). pii: E803. doi: 10.3390/ijms19030803.


In vivo imaging in the oral cavity by endoscopic optical coherence tomography.

Walther J, Schnabel C, Tetschke F, Rosenauer T, Golde J, Ebert N, Baumann M, Hannig C, Koch E.

J Biomed Opt. 2018 Mar;23(7):1-13. doi: 10.1117/1.JBO.23.7.071207.


Optical molecular imaging of corpora amylacea in human brain tissue.

Galli R, Meinhardt M, Koch E, Schackert G, Steiner G, Kirsch M, Uckermann O.

Biomed Tech (Berl). 2018 Oct 25;63(5):579-585. doi: 10.1515/bmt-2017-0073.


Bright light therapy versus physical exercise to prevent co-morbid depression and obesity in adolescents and young adults with attention-deficit / hyperactivity disorder: study protocol for a randomized controlled trial.

Mayer JS, Hees K, Medda J, Grimm O, Asherson P, Bellina M, Colla M, Ibáñez P, Koch E, Martinez-Nicolas A, Muntaner-Mas A, Rommel A, Rommelse N, de Ruiter S, Ebner-Priemer UW, Kieser M, Ortega FB, Thome J, Buitelaar JK, Kuntsi J, Ramos-Quiroga JA, Reif A, Freitag CM.

Trials. 2018 Feb 26;19(1):140. doi: 10.1186/s13063-017-2426-1.


Sexing of chicken eggs by fluorescence and Raman spectroscopy through the shell membrane.

Galli R, Preusse G, Schnabel C, Bartels T, Cramer K, Krautwald-Junghanns ME, Koch E, Steiner G.

PLoS One. 2018 Feb 23;13(2):e0192554. doi: 10.1371/journal.pone.0192554. eCollection 2018.


Pan European Phenological database (PEP725): a single point of access for European data.

Templ B, Koch E, Bolmgren K, Ungersböck M, Paul A, Scheifinger H, Rutishauser T, Busto M, Chmielewski FM, Hájková L, Hodzić S, Kaspar F, Pietragalla B, Romero-Fresneda R, Tolvanen A, Vučetič V, Zimmermann K, Zust A.

Int J Biometeorol. 2018 Jun;62(6):1109-1113. doi: 10.1007/s00484-018-1512-8. Epub 2018 Feb 18. Review.


Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila.

Joos JP, Saadatmand AR, Schnabel C, Viktorinová I, Brand T, Kramer M, Nattel S, Dobrev D, Tomancak P, Backs J, Kleinbongard P, Heusch G, Lorenz K, Koch E, Weber S, El-Armouche A.

Sci Rep. 2018 Feb 13;8(1):2940. doi: 10.1038/s41598-018-21372-3.


Reversal of visceral hypersensitivity in rat by Menthacarin® , a proprietary combination of essential oils from peppermint and caraway, coincides with mycobiome modulation.

Botschuijver S, Welting O, Levin E, Maria-Ferreira D, Koch E, Montijn RC, Seppen J, Hakvoort TBM, Schuren FHJ, de Jonge WJ, van den Wijngaard RM.

Neurogastroenterol Motil. 2018 Jun;30(6):e13299. doi: 10.1111/nmo.13299. Epub 2018 Jan 31.


Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography.

Golde J, Tetschke F, Walther J, Rosenauer T, Hempel F, Hannig C, Koch E, Kirsten L.

J Biomed Opt. 2018 Jan;23(7):1-8. doi: 10.1117/1.JBO.23.7.071203.


Low vitamin D levels affect outcomes of orthopedic spinal surgery: An observational study in clinical practice.

Breidebach JB, Koch EMW, Bornemann R, Roessler PP, Strauss A, Frey SP, Wirtz DC, Pflugmacher R.

Technol Health Care. 2018;26(2):305-317. doi: 10.3233/THC-171055.


MDPV in forensic routine cases: Psychotic and aggressive behavior in relation to plasma concentrations.

Diestelmann M, Zangl A, Herrle I, Koch E, Graw M, Paul LD.

Forensic Sci Int. 2018 Feb;283:72-84. doi: 10.1016/j.forsciint.2017.12.003. Epub 2017 Dec 8.


In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography.

Walther J, Golde J, Kirsten L, Tetschke F, Hempel F, Rosenauer T, Hannig C, Koch E.

J Biomed Opt. 2017 Dec;22(12):1-17. doi: 10.1117/1.JBO.22.12.121717.


Optical Analysis of Glioma: Fourier-Transform Infrared Spectroscopy Reveals the IDH1 Mutation Status.

Uckermann O, Juratli TA, Galli R, Conde M, Wiedemuth R, Krex D, Geiger K, Temme A, Schackert G, Koch E, Steiner G, Kirsch M.

Clin Cancer Res. 2018 Jun 1;24(11):2530-2538. doi: 10.1158/1078-0432.CCR-17-1795. Epub 2017 Dec 19.


Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.

Morvan F, Rondeau JM, Zou C, Minetti G, Scheufler C, Scharenberg M, Jacobi C, Brebbia P, Ritter V, Toussaint G, Koelbing C, Leber X, Schilb A, Witte F, Lehmann S, Koch E, Geisse S, Glass DJ, Lach-Trifilieff E.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12448-12453. doi: 10.1073/pnas.1707925114. Epub 2017 Nov 6.


In vivo imaging of murine vasodynamics analyzing different mouse strains by optical coherence tomography.

Müller G, Meissner S, Walther J, Koch E, Morawietz H.

Atheroscler Suppl. 2017 Nov;30:311-318. doi: 10.1016/j.atherosclerosissup.2017.05.023. Epub 2017 May 31.


Predictors of Help-Seeking Intentions in Operation Enduring Freedom and Operation Iraqi Freedom Veterans and Service Members.

Porcari C, Koch EI, Rauch SAM, Hoodin F, Ellison G, McSweeney L.

Mil Med. 2017 May;182(5):e1640-e1647. doi: 10.7205/MILMED-D-16-00105.


[A new positioning maneuver for treating a subtype of postural unsteadiness - based on a modified model of the utricular macula].

Koch E.

Laryngorhinootologie. 2017 Oct;96(10):678-684. doi: 10.1055/s-0043-118632. Epub 2017 Oct 10. German.


Erratum for: DNA Barcoding for Industrial Quality Assurance.

Sgamma T, Lockie-Williams C, Kreuzer M, Williams S, Scheyhing U, Koch E, Slater A, Howard C.

Planta Med. 2017 Dec;83(18):1430. doi: 10.1055/s-0043-120772. Epub 2017 Oct 10. No abstract available.


Experimental methods for flow and aerosol measurements in human airways and their replicas.

Lizal F, Jedelsky J, Morgan K, Bauer K, Llop J, Cossio U, Kassinos S, Verbanck S, Ruiz-Cabello J, Santos A, Koch E, Schnabel C.

Eur J Pharm Sci. 2018 Feb 15;113:95-131. doi: 10.1016/j.ejps.2017.08.021. Epub 2017 Aug 23. Review.


Motile cilia create fluid-mechanical microhabitats for the active recruitment of the host microbiome.

Nawroth JC, Guo H, Koch E, Heath-Heckman EAC, Hermanson JC, Ruby EG, Dabiri JO, Kanso E, McFall-Ngai M.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9510-9516. doi: 10.1073/pnas.1706926114. Epub 2017 Aug 23.


Variable stretch reduces the pro-inflammatory response of alveolar epithelial cells.

Rentzsch I, Santos CL, Huhle R, Ferreira JMC, Koch T, Schnabel C, Koch E, Pelosi P, Rocco PRM, Gama de Abreu M.

PLoS One. 2017 Aug 15;12(8):e0182369. doi: 10.1371/journal.pone.0182369. eCollection 2017.


Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT.

Kirsten L, Haußmann A, Schnabel C, Schmidt S, Cimalla P, Eng LM, Koch E.

Opt Express. 2017 Jun 26;25(13):14871-14882. doi: 10.1364/OE.25.014871.


A novel PLIF PEEK interbody cage with an impactionless insertion technology: A case series with a mid-term follow up of three years.

Struwe C, Hermann PC, Bornemann R, Plöger M, Roessler PP, Strauss AC, Rommelspacher Y, Koch EMW, Pflugmacher R.

Technol Health Care. 2017 Oct 23;25(5):949-957. doi: 10.3233/THC-160721.


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