Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 66

1.

Developmental Expression of the Cytosolic Sulfotransferases in Human Liver.

Dubaisi S, Caruso JA, Gaedigk R, Vyhlidal CA, Smith PC, Hines RN, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2019 Jun;47(6):592-600. doi: 10.1124/dmd.119.086363. Epub 2019 Mar 18.

2.

Farnesol induces fatty acid oxidation and decreases triglyceride accumulation in steatotic HepaRG cells.

Pant A, Rondini EA, Kocarek TA.

Toxicol Appl Pharmacol. 2019 Feb 15;365:61-70. doi: 10.1016/j.taap.2019.01.003. Epub 2019 Jan 3.

PMID:
30611723
3.

Regulation of Cytosolic Sulfotransferases in Models of Human Hepatocyte Development.

Dubaisi S, Barrett KG, Fang H, Guzman-Lepe J, Soto-Gutierrez A, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2018 Aug;46(8):1146-1156. doi: 10.1124/dmd.118.081398. Epub 2018 Jun 1.

4.
5.

Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat Hepatocytes.

Rondini EA, Duniec-Dmuchowski Z, Cukovic D, Dombkowski AA, Kocarek TA.

J Pharmacol Exp Ther. 2016 Aug;358(2):216-29. doi: 10.1124/jpet.116.233312. Epub 2016 May 25.

6.

Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Vitamin D Receptor in LS180 Human Colorectal Adenocarcinoma Cells.

Barrett KG, Fang H, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2016 Aug;44(8):1431-4. doi: 10.1124/dmd.116.070300. Epub 2016 Apr 29.

7.

Nonsterol Isoprenoids Activate Human Constitutive Androstane Receptor in an Isoform-Selective Manner in Primary Cultured Mouse Hepatocytes.

Rondini EA, Duniec-Dmuchowski Z, Kocarek TA.

Drug Metab Dispos. 2016 Apr;44(4):595-604. doi: 10.1124/dmd.115.068551. Epub 2016 Jan 21.

8.
9.

Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes.

Rondini EA, Pant A, Kocarek TA.

J Pharmacol Exp Ther. 2015 Dec;355(3):429-41. doi: 10.1124/jpet.115.226365. Epub 2015 Oct 1.

10.

Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation.

Barrett KG, Fang H, Cukovic D, Dombkowski AA, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2015 Jul;43(7):1061-70. doi: 10.1124/dmd.114.061440. Epub 2015 May 6.

11.

Regulation of human cytosolic sulfotransferases 1C2 and 1C3 by nuclear signaling pathways in LS180 colorectal adenocarcinoma cells.

Rondini EA, Fang H, Runge-Morris M, Kocarek TA.

Drug Metab Dispos. 2014 Mar;42(3):361-8. doi: 10.1124/dmd.113.055673. Epub 2013 Dec 11.

12.

Expression of the orphan cytosolic sulfotransferase SULT1C3 in human intestine: characterization of the transcript variant and implications for function.

Duniec-Dmuchowski Z, Rondini EA, Tibbs ZE, Falany CN, Runge-Morris M, Kocarek TA.

Drug Metab Dispos. 2014 Mar;42(3):352-60. doi: 10.1124/dmd.113.055665. Epub 2013 Dec 11. Erratum in: Drug Metab Dispos. 2014 May;42(5):853.

13.

Expression of the sulfotransferase 1C family: implications for xenobiotic toxicity.

Runge-Morris M, Kocarek TA.

Drug Metab Rev. 2013 Nov;45(4):450-9. doi: 10.3109/03602532.2013.835634. Epub 2013 Sep 12. Review.

PMID:
24028175
14.

Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency.

Barrett KG, Fang H, Gargano MD, Markovich D, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2013 Aug;41(8):1505-13. doi: 10.1124/dmd.113.051912. Epub 2013 May 14.

15.

Regulation of the cytosolic sulfotransferases by nuclear receptors.

Runge-Morris M, Kocarek TA, Falany CN.

Drug Metab Rev. 2013 Feb;45(1):15-33. doi: 10.3109/03602532.2012.748794. Review.

16.

p-Anilinoaniline enhancement of dioxin-induced CYP1A1 transcription and aryl hydrocarbon receptor occupancy of CYP1A1 promoter: role of the cell cycle.

Elliott A, Joiakim A, Mathieu PA, Duniec-Dmuchowski Z, Kocarek TA, Reiners JJ Jr.

Drug Metab Dispos. 2012 May;40(5):1032-40. doi: 10.1124/dmd.111.042549. Epub 2012 Feb 16.

17.

Site-directed mutagenesis of human cytosolic sulfotransferase (SULT) 2B1b to phospho-mimetic Ser348Asp results in an isoform with increased catalytic activity.

Salman ED, He D, Runge-Morris M, Kocarek TA, Falany CN.

J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):315-23. doi: 10.1016/j.jsbmb.2011.07.010. Epub 2011 Aug 6.

18.

Regulation of estrogen sulfotransferase expression by confluence of MCF10A breast epithelial cells: role of the aryl hydrocarbon receptor.

Fu J, Fang H, Paulsen M, Ljungman M, Kocarek TA, Runge-Morris M.

J Pharmacol Exp Ther. 2011 Nov;339(2):597-606. doi: 10.1124/jpet.111.185173. Epub 2011 Aug 9.

19.

Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.

Runge-Morris M, Kocarek TA.

PPAR Res. 2009;2009:728941. doi: 10.1155/2009/728941. Epub 2009 Aug 10.

20.

24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor activation.

Cook IT, Duniec-Dmuchowski Z, Kocarek TA, Runge-Morris M, Falany CN.

Drug Metab Dispos. 2009 Oct;37(10):2069-78. doi: 10.1124/dmd.108.025759. Epub 2009 Jul 9.

21.

Regulation of hepatic sulfotransferase (SULT) 1E1 expression and effects on estrogenic activity in cystic fibrosis (CF).

Falany CN, He D, Li L, Falany JL, Wilborn TW, Kocarek TA, Runge-Morris M.

J Steroid Biochem Mol Biol. 2009 Mar;114(1-2):113-9. doi: 10.1016/j.jsbmb.2009.02.009. Epub 2009 Mar 3.

22.

Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression.

Fu J, Weise AM, Falany JL, Falany CN, Thibodeau BJ, Miller FR, Kocarek TA, Runge-Morris M.

Breast Cancer Res Treat. 2010 Feb;120(1):35-45. doi: 10.1007/s10549-009-0363-8. Epub 2009 Mar 24.

23.

Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition.

Duniec-Dmuchowski Z, Fang HL, Strom SC, Ellis E, Runge-Morris M, Kocarek TA.

Drug Metab Dispos. 2009 Apr;37(4):900-8. doi: 10.1124/dmd.108.025130. Epub 2009 Jan 21.

24.

Age- and sex-dependent expression of multiple murine hepatic hydroxysteroid sulfotransferase (SULT2A) genes.

Kocarek TA, Duanmu Z, Fang HL, Runge-Morris M.

Biochem Pharmacol. 2008 Oct 15;76(8):1036-46. doi: 10.1016/j.bcp.2008.07.032. Epub 2008 Aug 5.

25.

Suppression of CYP2B induction by alendronate-mediated farnesyl diphosphate synthase inhibition in primary cultured rat hepatocytes.

Jackson NM, Kocarek TA.

Drug Metab Dispos. 2008 Oct;36(10):2030-6. doi: 10.1124/dmd.108.022558. Epub 2008 Jul 10.

26.

Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists.

Duniec-Dmuchowski Z, Ellis E, Strom SC, Kocarek TA.

Biochem Pharmacol. 2007 Nov 15;74(10):1535-40. Epub 2007 Aug 3.

27.

Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.

Fang HL, Strom SC, Ellis E, Duanmu Z, Fu J, Duniec-Dmuchowski Z, Falany CN, Falany JL, Kocarek TA, Runge-Morris M.

J Pharmacol Exp Ther. 2007 Nov;323(2):586-98. Epub 2007 Aug 8.

PMID:
17687072
28.

Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in MCF10A breast epithelial cells.

Thomas RD, Green MR, Wilson C, Weckle AL, Duanmu Z, Kocarek TA, Runge-Morris M.

Chem Biol Interact. 2006 Apr 15;160(3):204-16. Epub 2006 Mar 9.

PMID:
16527260
29.

Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver.

Duanmu Z, Weckle A, Koukouritaki SB, Hines RN, Falany JL, Falany CN, Kocarek TA, Runge-Morris M.

J Pharmacol Exp Ther. 2006 Mar;316(3):1310-7. Epub 2005 Dec 9.

PMID:
16339912
30.

Regulation of sulfotransferases by xenobiotic receptors.

Runge-Morris M, Kocarek TA.

Curr Drug Metab. 2005 Aug;6(4):299-307. Review.

PMID:
16101570
31.

Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor alpha transcription factor.

Fang HL, Strom SC, Cai H, Falany CN, Kocarek TA, Runge-Morris M.

Mol Pharmacol. 2005 Apr;67(4):1257-67. Epub 2005 Jan 5.

PMID:
15635043
32.

Regulation of glucocorticoid-inducible hydroxysteroid sulfotransferase (SULT2A-40/41) gene transcription in primary cultured rat hepatocytes: role of CCAAT/enhancer-binding protein liver-enriched transcription factors.

Fang HL, Abdolalipour M, Duanmu Z, Smigelski JR, Weckle A, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2005 Jan;33(1):147-56. Epub 2004 Oct 22.

PMID:
15502011
33.

Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes.

Shenoy SD, Spencer TA, Mercer-Haines NA, Abdolalipour M, Wurster WL, Runge-Morris M, Kocarek TA.

Mol Pharmacol. 2004 May;65(5):1302-12.

PMID:
15102959
34.

CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.

Shenoy SD, Spencer TA, Mercer-Haines NA, Alipour M, Gargano MD, Runge-Morris M, Kocarek TA.

Drug Metab Dispos. 2004 Jan;32(1):66-71.

PMID:
14709622
35.

Transactivation of glucocorticoid-inducible rat aryl sulfotransferase (SULT1A1) gene transcription.

Fang HL, Shenoy S, Duanmu Z, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2003 Nov;31(11):1378-81.

PMID:
14570770
36.

Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes.

Kocarek TA, Shenoy SD, Mercer-Haines NA, Runge-Morris M.

J Pharmacol Toxicol Methods. 2002 May-Jun;47(3):177-87.

PMID:
12628309
37.

Suppression of cytochrome P450 3A protein levels by proteasome inhibitors.

Zangar RC, Kocarek TA, Shen S, Bollinger N, Dahn MS, Lee DW.

J Pharmacol Exp Ther. 2003 Jun;305(3):872-9. Epub 2003 Mar 6.

PMID:
12626652
38.

Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes.

Kocarek TA, Dahn MS, Cai H, Strom SC, Mercer-Haines NA.

Drug Metab Dispos. 2002 Dec;30(12):1400-5.

PMID:
12433810
40.

Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents.

Schuetz E, Lan L, Yasuda K, Kim R, Kocarek TA, Schuetz J, Strom S.

Mol Pharmacol. 2002 Sep;62(3):439-45.

PMID:
12181418
41.

Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes.

Duanmu Z, Locke D, Smigelski J, Wu W, Dahn MS, Falany CN, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2002 Sep;30(9):997-1004.

PMID:
12167565
42.

Random monoallelic expression of three genes clustered within 60 kb of mouse t complex genomic DNA.

Sano Y, Shimada T, Nakashima H, Nicholson RH, Eliason JF, Kocarek TA, Ko MS.

Genome Res. 2001 Nov;11(11):1833-41.

43.

Transcriptional regulation of rat hepatic aryl sulfotransferase (SULT1A1) gene expression by glucocorticoids.

Duanmu Z, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2001 Aug;29(8):1130-5.

PMID:
11454732
44.

Sex-dependent regulation by dexamethasone of murine hydroxysteroid sulfotransferase gene expression.

Wu W, Kocarek TA, Runge-Morris M.

Toxicol Lett. 2001 Mar 8;119(3):235-46.

PMID:
11246177
45.
46.

Identification of a ubiquitination-Target/Substrate-interaction domain of cytochrome P-450 (CYP) 2E1.

Banerjee A, Kocarek TA, Novak RF.

Drug Metab Dispos. 2000 Feb;28(2):118-24.

PMID:
10640507
48.
50.

Differential regulation of individual sulfotransferase isoforms by phenobarbital in male rat liver.

Runge-Morris M, Rose K, Falany CN, Kocarek TA.

Drug Metab Dispos. 1998 Aug;26(8):795-801.

PMID:
9698295

Supplemental Content

Loading ...
Support Center