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Items: 1 to 50 of 139

1.

Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood.

Goodman SJ, Roubinov DS, Bush NR, Park M, Farré P, Emberly E, Hertzman C, Essex MJ, Kobor MS, Boyce WT.

Dev Sci. 2018 Sep 3:e12739. doi: 10.1111/desc.12739. [Epub ahead of print]

PMID:
30176105
2.

PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores.

Chen LM, Yao N, Garg E, Zhu Y, Nguyen TTT, Pokhvisneva I, Hari Dass SA, Unternaehrer E, Gaudreau H, Forest M, McEwen LM, MacIsaac JL, Kobor MS, Greenwood CMT, Silveira PP, Meaney MJ, O'Donnell KJ.

BMC Bioinformatics. 2018 Aug 8;19(1):295. doi: 10.1186/s12859-018-2289-9.

3.

Variability in DNA methylation at the serotonin transporter gene promoter: epigenetic mechanism or cell-type artifact?

Moore SR, Kobor MS.

Mol Psychiatry. 2018 Aug 6. doi: 10.1038/s41380-018-0121-6. [Epub ahead of print] No abstract available.

PMID:
30082839
4.

An epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior.

Conradt E, Adkins DE, Crowell SE, Monk C, Kobor MS.

Dev Psychopathol. 2018 Aug;30(3):881-890. doi: 10.1017/S0954579418000688.

5.

The early care environment and DNA methylome variation in childhood.

Garg E, Chen L, Nguyen TTT, Pokhvisneva I, Chen LM, Unternaehrer E, MacIsaac JL, McEwen LM, Mah SM, Gaudreau H, Levitan R, Moss E, Sokolowski MB, Kennedy JL, Steiner MS, Meaney MJ, Holbrook JD, Silveira PP, Karnani N, Kobor MS, O'Donnell KJ; Mavan Study Team.

Dev Psychopathol. 2018 Aug;30(3):891-903. doi: 10.1017/S0954579418000627.

PMID:
30068421
6.

Comparison of DNA methylation measured by Illumina 450K and EPIC BeadChips in blood of newborns and 14-year-old children.

Solomon O, MacIsaac J, Quach H, Tindula G, Kobor MS, Huen K, Meaney MJ, Eskenazi B, Barcellos LF, Holland N.

Epigenetics. 2018;13(6):655-664. doi: 10.1080/15592294.2018.1497386. Epub 2018 Aug 15.

7.

Reproduction predicts shorter telomeres and epigenetic age acceleration among young adult women.

Ryan CP, Hayes MG, Lee NR, McDade TW, Jones MJ, Kobor MS, Kuzawa CW, Eisenberg DTA.

Sci Rep. 2018 Jul 23;8(1):11100. doi: 10.1038/s41598-018-29486-4.

8.

Early-life socioeconomic disadvantage, not current, predicts accelerated epigenetic aging of monocytes.

Austin MK, Chen E, Ross KM, McEwen LM, Maclsaac JL, Kobor MS, Miller GE.

Psychoneuroendocrinology. 2018 Nov;97:131-134. doi: 10.1016/j.psyneuen.2018.07.007. Epub 2018 Jul 5.

PMID:
30016711
9.

Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents.

Horvath S, Stein DJ, Phillips N, Heany SJ, Kobor MS, Lin DTS, Myer L, Zar HJ, Levine AJ, Hoare J.

AIDS. 2018 Jul 17;32(11):1465-1474. doi: 10.1097/QAD.0000000000001854.

PMID:
29746298
10.

Cysteinyl Leukotriene Receptor 1 and Health Effects of Particulate Exposure in Asthma.

Rabinovitch N, Jones MJ, Faino A, Strand M, Morin AM, MacIsaac J, Reynolds PR, Singh A, Kobor MS, Gelfand EW, Carlsten C.

Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S129. doi: 10.1513/AnnalsATS.201706-469MG.

PMID:
29676619
11.

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.

Clifford RL, Fishbane N, Patel J, MacIsaac JL, McEwen LM, Fisher AJ, Brandsma CA, Nair P, Kobor MS, Hackett TL, Knox AJ.

Clin Epigenetics. 2018 Mar 5;10:32. doi: 10.1186/s13148-018-0464-5. eCollection 2018.

12.

Epigenetic analysis of human postmortem brain tissue.

Islam SA, Lussier AA, Kobor MS.

Handb Clin Neurol. 2018;150:237-261. doi: 10.1016/B978-0-444-63639-3.00017-7. Review.

PMID:
29496144
13.

Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time.

Forest M, O'Donnell KJ, Voisin G, Gaudreau H, MacIsaac JL, McEwen LM, Silveira PP, Steiner M, Kobor MS, Meaney MJ, Greenwood CMT.

Epigenetics. 2018;13(1):19-32. doi: 10.1080/15592294.2017.1411443. Epub 2018 Jan 30.

14.

DNA methylation as a predictor of fetal alcohol spectrum disorder.

Lussier AA, Morin AM, MacIsaac JL, Salmon J, Weinberg J, Reynolds JN, Pavlidis P, Chudley AE, Kobor MS.

Clin Epigenetics. 2018 Jan 12;10:5. doi: 10.1186/s13148-018-0439-6. eCollection 2018.

15.

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up.

O'Donnell KJ, Chen L, MacIsaac JL, McEwen LM, Nguyen T, Beckmann K, Zhu Y, Chen LM, Brooks-Gunn J, Goldman D, Grigorenko EL, Leckman JF, Diorio J, Karnani N, Olds DL, Holbrook JD, Kobor MS, Meaney MJ.

Transl Psychiatry. 2018 Jan 10;8(1):15. doi: 10.1038/s41398-017-0063-9.

16.

Choice of surrogate tissue influences neonatal EWAS findings.

Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N.

BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x.

17.

Worldwide patterns of human epigenetic variation.

Carja O, MacIsaac JL, Mah SM, Henn BM, Kobor MS, Feldman MW, Fraser HB.

Nat Ecol Evol. 2017 Oct;1(10):1577-1583. doi: 10.1038/s41559-017-0299-z. Epub 2017 Aug 28.

PMID:
29185505
18.

Epigenetic correlates of neonatal contact in humans.

Moore SR, McEwen LM, Quirt J, Morin A, Mah SM, Barr RG, Boyce WT, Kobor MS.

Dev Psychopathol. 2017 Dec;29(5):1517-1538. doi: 10.1017/S0954579417001213.

PMID:
29162165
19.

DNA methylation signatures in peripheral blood mononuclear cells from a lifestyle intervention for women at midlife: a pilot randomized controlled trial.

McEwen LM, Gatev EG, Jones MJ, MacIsaac JL, McAllister MM, Goulding RE, Madden KM, Dawes MG, Kobor MS, Ashe MC.

Appl Physiol Nutr Metab. 2018 Mar;43(3):233-239. doi: 10.1139/apnm-2017-0436. Epub 2017 Oct 19.

PMID:
29049890
20.

RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability.

Chang EY, Novoa CA, Aristizabal MJ, Coulombe Y, Segovia R, Chaturvedi R, Shen Y, Keong C, Tam AS, Jones SJM, Masson JY, Kobor MS, Stirling PC.

J Cell Biol. 2017 Dec 4;216(12):3991-4005. doi: 10.1083/jcb.201703168. Epub 2017 Oct 17.

21.

Principles and Challenges of Applying Epigenetic Epidemiology to Psychology.

Jones MJ, Moore SR, Kobor MS.

Annu Rev Psychol. 2018 Jan 4;69:459-485. doi: 10.1146/annurev-psych-122414-033653. Epub 2017 Oct 16.

PMID:
29035689
22.

DNA methylation patterns are related to co-morbidity status and circulating C-reactive protein levels in the nursing home elderly.

Verschoor CP, McEwen LM, Kobor MS, Loeb MB, Bowdish DME.

Exp Gerontol. 2018 May;105:47-52. doi: 10.1016/j.exger.2017.10.010. Epub 2017 Oct 12.

PMID:
29032243
23.

Birth weight and postnatal microbial exposures predict the distribution of peripheral blood leukocyte subsets in young adults in the Philippines.

McDade TW, Jones MJ, Miller G, Borja J, Kobor MS, Kuzawa CW.

J Dev Orig Health Dis. 2018 Apr;9(2):198-207. doi: 10.1017/S2040174417000794. Epub 2017 Oct 11.

PMID:
29017617
24.

Exploring genetic influences underlying acute aerobic exercise effects on motor learning.

Mang CS, McEwen LM, MacIsaac JL, Snow NJ, Campbell KL, Kobor MS, Ross CJD, Boyd LA.

Sci Rep. 2017 Sep 21;7(1):12123. doi: 10.1038/s41598-017-12422-3.

25.

Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume.

Davis EG, Humphreys KL, McEwen LM, Sacchet MD, Camacho MC, MacIsaac JL, Lin DTS, Kobor MS, Gotlib IH.

Transl Psychiatry. 2017 Aug 29;7(8):e1223. doi: 10.1038/tp.2017.188.

26.

Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs.

Morin AM, Gatev E, McEwen LM, MacIsaac JL, Lin DTS, Koen N, Czamara D, Räikkönen K, Zar HJ, Koenen K, Stein DJ, Kobor MS, Jones MJ.

Clin Epigenetics. 2017 Jul 25;9:75. doi: 10.1186/s13148-017-0370-2. eCollection 2017.

27.

BECon: a tool for interpreting DNA methylation findings from blood in the context of brain.

Edgar RD, Jones MJ, Meaney MJ, Turecki G, Kobor MS.

Transl Psychiatry. 2017 Aug 1;7(8):e1187. doi: 10.1038/tp.2017.171.

28.

Blood and nasal epigenetics correlate with allergic rhinitis symptom development in the environmental exposure unit.

North ML, Jones MJ, MacIsaac JL, Morin AM, Steacy LM, Gregor A, Kobor MS, Ellis AK.

Allergy. 2018 Jan;73(1):196-205. doi: 10.1111/all.13263. Epub 2017 Sep 22.

PMID:
28755526
29.

DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment.

Brückmann C, Islam SA, MacIsaac JL, Morin AM, Karle KN, Di Santo A, Wüst R, Lang I, Batra A, Kobor MS, Nieratschker V.

Sci Rep. 2017 Jul 26;7(1):6605. doi: 10.1038/s41598-017-06847-z.

30.

Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood.

McDade TW, Ryan C, Jones MJ, MacIsaac JL, Morin AM, Meyer JM, Borja JB, Miller GE, Kobor MS, Kuzawa CW.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7611-7616. doi: 10.1073/pnas.1620661114. Epub 2017 Jul 3.

31.

The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study.

Verschoor CP, McEwen LM, Kohli V, Wolfson C, Bowdish DM, Raina P, Kobor MS, Balion C.

BMC Genet. 2017 Jun 21;18(1):57. doi: 10.1186/s12863-017-0525-3.

32.

Trends in DNA Methylation with Age Replicate Across Diverse Human Populations.

Gopalan S, Carja O, Fagny M, Patin E, Myrick JW, McEwen LM, Mah SM, Kobor MS, Froment A, Feldman MW, Quintana-Murci L, Henn BM.

Genetics. 2017 Jul;206(3):1659-1674. doi: 10.1534/genetics.116.195594. Epub 2017 May 22.

33.

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth.

Girchenko P, Lahti J, Czamara D, Knight AK, Jones MJ, Suarez A, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Kobor MS, Smith AK, Binder EB, Räikkönen K.

Clin Epigenetics. 2017 May 8;9:49. doi: 10.1186/s13148-017-0349-z. eCollection 2017.

34.

The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop.

Budinger GRS, Kohanski RA, Gan W, Kobor MS, Amaral LA, Armanios M, Kelsey KT, Pardo A, Tuder R, Macian F, Chandel N, Vaughan D, Rojas M, Mora AL, Kovacs E, Duncan SR, Finkel T, Choi A, Eickelberg O, Chen D, Agusti A, Selman M, Balch WE, Busse P, Lin A, Morimoto R, Sznajder JI, Thannickal VJ.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1492-1500. doi: 10.1093/gerona/glx090. Review.

35.

Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region.

McEwen LM, Morin AM, Edgar RD, MacIsaac JL, Jones MJ, Dow WH, Rosero-Bixby L, Kobor MS, Rehkopf DH.

Epigenetics Chromatin. 2017 Apr 27;10:21. doi: 10.1186/s13072-017-0128-2. eCollection 2017.

36.

Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.

Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group.

BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1.

37.

Epigenetics studies of fetal alcohol spectrum disorder: where are we now?

Lussier AA, Weinberg J, Kobor MS.

Epigenomics. 2017 Mar;9(3):291-311. doi: 10.2217/epi-2016-0163. Epub 2017 Feb 17. Review.

38.

An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs.

Edgar RD, Jones MJ, Robinson WP, Kobor MS.

Clin Epigenetics. 2017 Feb 2;9:11. doi: 10.1186/s13148-017-0320-z. eCollection 2017.

39.

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up.

Gref A, Merid SK, Gruzieva O, Ballereau S, Becker A, Bellander T, Bergström A, Bossé Y, Bottai M, Chan-Yeung M, Fuertes E, Ierodiakonou D, Jiang R, Joly S, Jones M, Kobor MS, Korek M, Kozyrskyj AL, Kumar A, Lemonnier N, MacIntyre E, Ménard C, Nickle D, Obeidat M, Pellet J, Standl M, Sääf A, Söderhäll C, Tiesler CMT, van den Berge M, Vonk JM, Vora H, Xu CJ, Antó JM, Auffray C, Brauer M, Bousquet J, Brunekreef B, Gauderman WJ, Heinrich J, Kere J, Koppelman GH, Postma D, Carlsten C, Pershagen G, Melén E.

Am J Respir Crit Care Med. 2017 May 15;195(10):1373-1383. doi: 10.1164/rccm.201605-1026OC.

40.

Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

Steunou AL, Cramet M, Rossetto D, Aristizabal MJ, Lacoste N, Drouin S, Côté V, Paquet E, Utley RT, Krogan N, Robert F, Kobor MS, Côté J.

Mol Cell Biol. 2016 Oct 28;36(22):2768-2781. Print 2016 Nov 15.

41.

Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity.

Esposito EA, Jones MJ, Doom JR, MacIsaac JL, Gunnar MR, Kobor MS.

Dev Psychopathol. 2016 Nov;28(4pt2):1385-1399. Epub 2016 Feb 5.

42.

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.

Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL.

Genome Biol. 2016 Aug 11;17(1):171. doi: 10.1186/s13059-016-1030-0.

43.

DNA methylation signature of human fetal alcohol spectrum disorder.

Portales-Casamar E, Lussier AA, Jones MJ, MacIsaac JL, Edgar RD, Mah SM, Barhdadi A, Provost S, Lemieux-Perreault LP, Cynader MS, Chudley AE, Dubé MP, Reynolds JN, Pavlidis P, Kobor MS.

Epigenetics Chromatin. 2016 Jun 29;9:25. doi: 10.1186/s13072-016-0074-4. eCollection 2016.

44.

Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation.

Clifford RL, Jones MJ, MacIsaac JL, McEwen LM, Goodman SJ, Mostafavi S, Kobor MS, Carlsten C.

J Allergy Clin Immunol. 2017 Jan;139(1):112-121. doi: 10.1016/j.jaci.2016.03.046. Epub 2016 May 10.

PMID:
27321436
45.

Epigenetics: A New Model for Intracellular Parasite-Host Cell Regulation.

Robert McMaster W, Morrison CJ, Kobor MS.

Trends Parasitol. 2016 Jul;32(7):515-521. doi: 10.1016/j.pt.2016.04.002. Epub 2016 Apr 30. Review.

PMID:
27142564
46.

A single flexible RNAPII-CTD integrates many different transcriptional programs.

Aristizabal MJ, Kobor MS.

Transcription. 2016 Mar 14;7(2):50-6. doi: 10.1080/21541264.2016.1163451. Epub 2016 Mar 17.

47.

Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL).

Koestler DC, Jones MJ, Usset J, Christensen BC, Butler RA, Kobor MS, Wiencke JK, Kelsey KT.

BMC Bioinformatics. 2016 Mar 8;17:120. doi: 10.1186/s12859-016-0943-7.

48.

DNA methylation profiling in human Huntington's disease brain.

De Souza RA, Islam SA, McEwen LM, Mathelier A, Hill A, Mah SM, Wasserman WW, Kobor MS, Leavitt BR.

Hum Mol Genet. 2016 May 15;25(10):2013-2030. Epub 2016 Mar 6.

PMID:
26953320
49.

Low birth weight associates with hippocampal gene expression.

Buschdorf JP, Ong ML, Ong SX, MacIsaac JL, Chng K, Kobor MS, Meaney MJ, Holbrook JD.

Neuroscience. 2016 Mar 24;318:190-205. doi: 10.1016/j.neuroscience.2016.01.013. Epub 2016 Jan 12.

PMID:
26791528
50.

Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples.

Teh AL, Pan H, Lin X, Lim YI, Patro CP, Cheong CY, Gong M, MacIsaac JL, Kwoh CK, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Holbrook JD, Karnani N.

Epigenetics. 2016;11(1):36-48. doi: 10.1080/15592294.2015.1132136. Epub 2016 Jan 19.

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