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Items: 40

1.

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state.

Bernardo AS, Jouneau A, Marks H, Kensche P, Kobolak J, Freude K, Hall V, Feher A, Polgar Z, Sartori C, Bock I, Louet C, Faial T, Kerstens HHD, Bouissou C, Parsonage G, Mashayekhi K, Smith JC, Lazzari G, Hyttel P, Stunnenberg HG, Huynen M, Pedersen RA, Dinnyes A.

Biol Open. 2018 Aug 17;7(8). pii: bio033282. doi: 10.1242/bio.033282.

2.

The Potency of Induced Pluripotent Stem Cells in Cartilage Regeneration and Osteoarthritis Treatment.

Murphy C, Mobasheri A, Táncos Z, Kobolák J, Dinnyés A.

Adv Exp Med Biol. 2018;1079:55-68. doi: 10.1007/5584_2017_141.

PMID:
29270885
3.

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.

Ochalek A, Mihalik B, Avci HX, Chandrasekaran A, Téglási A, Bock I, Giudice ML, Táncos Z, Molnár K, László L, Nielsen JE, Holst B, Freude K, Hyttel P, Kobolák J, Dinnyés A.

Alzheimers Res Ther. 2017 Dec 1;9(1):90. doi: 10.1186/s13195-017-0317-z.

4.

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells.

Chandrasekaran A, Avci HX, Ochalek A, Rösingh LN, Molnár K, László L, Bellák T, Téglási A, Pesti K, Mike A, Phanthong P, Bíró O, Hall V, Kitiyanant N, Krause KH, Kobolák J, Dinnyés A.

Stem Cell Res. 2017 Dec;25:139-151. doi: 10.1016/j.scr.2017.10.010. Epub 2017 Oct 14.

5.

Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism.

Nagy J, Kobolák J, Berzsenyi S, Ábrahám Z, Avci HX, Bock I, Bekes Z, Hodoscsek B, Chandrasekaran A, Téglási A, Dezső P, Koványi B, Vörös ET, Fodor L, Szél T, Németh K, Balázs A, Dinnyés A, Lendvai B, Lévay G, Román V.

Transl Psychiatry. 2017 Jul 25;7(7):e1179. doi: 10.1038/tp.2017.144.

6.

Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD).

Varga E, Nemes C, Bock I, Táncos Z, Berzsenyi S, Lévay G, Román V, Kobolák J, Dinnyés A.

Stem Cell Res. 2017 May;21:19-22. doi: 10.1016/j.scr.2017.03.013. Epub 2017 Mar 18.

7.

Establishment of a rabbit induced pluripotent stem cell (RbiPSC) line using lentiviral delivery of human pluripotency factors.

Táncos Z, Nemes C, Varga E, Bock I, Rungarunlert S, Tharasanit T, Techakumphu M, Kobolák J, Dinnyés A.

Stem Cell Res. 2017 May;21:16-18. doi: 10.1016/j.scr.2017.03.010. Epub 2017 Mar 16.

8.

Real architecture For 3D Tissue (RAFT™) culture system improves viability and maintains insulin and glucagon production of mouse pancreatic islet cells.

Szebeni GJ, Tancos Z, Feher LZ, Alfoldi R, Kobolak J, Dinnyes A, Puskas LG.

Cytotechnology. 2017 Apr;69(2):359-369. doi: 10.1007/s10616-017-0067-6. Epub 2017 Feb 8.

9.

Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy.

Ochalek A, Szczesna K, Petazzi P, Kobolak J, Dinnyes A.

Stem Cells Int. 2016;2016:5838934. doi: 10.1155/2016/5838934. Epub 2016 Dec 25. Review.

10.

Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3.

Takacs E, Boto P, Simo E, Csuth TI, Toth BM, Raveh-Amit H, Pap A, Kovács EG, Kobolak J, Benkö S, Dinnyes A, Szatmari I.

J Immunol. 2017 Jan 1;198(1):239-248. Epub 2016 Nov 16.

11.

Targeted next generation sequencing of a panel of autism-related genes identifies an EHMT1 mutation in a Kleefstra syndrome patient with autism and normal intellectual performance.

Bock I, Németh K, Pentelényi K, Balicza P, Balázs A, Molnár MJ, Román V, Nagy J, Lévay G, Kobolák J, Dinnyés A.

Gene. 2016 Dec 31;595(2):131-141. doi: 10.1016/j.gene.2016.09.027. Epub 2016 Sep 17.

PMID:
27651234
12.

Establishment of EHMT1 mutant induced pluripotent stem cell (iPSC) line from a 11-year-old Kleefstra syndrome (KS) patient with autism and normal intellectual performance.

Varga E, Nemes C, Táncos Z, Bock I, Berzsenyi S, Lévay G, Román V, Kobolák J, Dinnyés A.

Stem Cell Res. 2016 Nov;17(3):531-533. doi: 10.1016/j.scr.2016.09.031. Epub 2016 Oct 2.

13.

Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of Mucopolysaccharidosis type II (MPS II) disorder.

Varga E, Nemes C, Kovács E, Bock I, Varga N, Fehér A, Dinnyés A, Kobolák J.

Stem Cell Res. 2016 Nov;17(3):514-516. doi: 10.1016/j.scr.2016.09.035. Epub 2016 Oct 3.

14.

Generation of Mucopolysaccharidosis type II (MPS II) human induced pluripotent stem cell (iPSC) line from a 1-year-old male with pathogenic IDS mutation.

Varga E, Nemes C, Bock I, Varga N, Fehér A, Dinnyés A, Kobolák J.

Stem Cell Res. 2016 Nov;17(3):482-484. doi: 10.1016/j.scr.2016.09.033. Epub 2016 Oct 1.

15.

Generation of Mucopolysaccharidosis type II (MPS II) human induced pluripotent stem cell (iPSC) line from a 3-year-old male with pathogenic IDS mutation.

Varga E, Nemes C, Bock I, Varga N, Fehér A, Kobolák J, Dinnyés A.

Stem Cell Res. 2016 Nov;17(3):479-481. doi: 10.1016/j.scr.2016.09.032. Epub 2016 Oct 1.

16.

Generation of Mucopolysaccharidosis type II (MPS II) human induced pluripotent stem cell (iPSC) line from a 7-year-old male with pathogenic IDS mutation.

Varga E, Nemes C, Bock I, Varga N, Fehér A, Kobolák J, Dinnyés A.

Stem Cell Res. 2016 Nov;17(3):463-465. doi: 10.1016/j.scr.2016.09.034. Epub 2016 Oct 1.

17.

In vitro models of cancer stem cells and clinical applications.

S Franco S, Szczesna K, Iliou MS, Al-Qahtani M, Mobasheri A, Kobolák J, Dinnyés A.

BMC Cancer. 2016 Sep 30;16(Suppl 2):738. Review.

18.

Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research.

Chandrasekaran A, Avci HX, Leist M, Kobolák J, Dinnyés A.

Front Cell Neurosci. 2016 Sep 26;10:215. eCollection 2016. Review.

19.

Establishment of induced pluripotent stem cell (iPSC) line from a 75-year old patient with late onset Alzheimer's disease (LOAD).

Táncos Z, Varga E, Kovács E, Dinnyés A, Kobolák J.

Stem Cell Res. 2016 Jul;17(1):81-83. doi: 10.1016/j.scr.2016.05.013. Epub 2016 May 24.

20.

Establishment of induced pluripotent stem cell (iPSC) line from a 63-year old patient with late onset Alzheimer's disease (LOAD).

Chandrasekaran A, Varga E, Nemes C, Táncos Z, Kobolák J, Dinnyés A.

Stem Cell Res. 2016 Jul;17(1):78-80. doi: 10.1016/j.scr.2016.05.014. Epub 2016 May 24.

21.

Establishment of induced pluripotent stem cell (iPSC) line from an 84-year old patient with late onset Alzheimer's disease (LOAD).

Táncos Z, Varga E, Kovács E, Dinnyés A, Kobolák J.

Stem Cell Res. 2016 Jul;17(1):75-77. doi: 10.1016/j.scr.2016.05.016. Epub 2016 May 24.

22.

Establishment of induced pluripotent stem cell (iPSC) line from a 57-year old patient with sporadic Alzheimer's disease.

Ochalek A, Nemes C, Varga E, Táncos Z, Kobolák J, Dinnyés A.

Stem Cell Res. 2016 Jul;17(1):72-74. doi: 10.1016/j.scr.2016.05.020. Epub 2016 May 25.

23.

Establishment of PSEN1 mutant induced pluripotent stem cell (iPSC) line from an Alzheimer's disease (AD) female patient.

Nemes C, Varga E, Táncos Z, Bock I, Francz B, Kobolák J, Dinnyés A.

Stem Cell Res. 2016 Jul;17(1):69-71. doi: 10.1016/j.scr.2016.05.019. Epub 2016 May 24. No abstract available.

24.

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities.

Schmidt BZ, Lehmann M, Gutbier S, Nembo E, Noel S, Smirnova L, Forsby A, Hescheler J, Avci HX, Hartung T, Leist M, Kobolák J, Dinnyés A.

Arch Toxicol. 2017 Jan;91(1):1-33. doi: 10.1007/s00204-016-1805-9. Epub 2016 Aug 4. Review.

PMID:
27492622
25.

The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF.

Zhou S, Ochalek A, Szczesna K, Avci HX, Kobolák J, Varga E, Rasmussen M, Holst B, Cirera S, Hyttel P, Freude KK, Dinnyés A.

Differentiation. 2016 Oct - Nov;92(4):183-194. doi: 10.1016/j.diff.2016.06.002. Epub 2016 Jun 16.

PMID:
27321088
26.

Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.

Zhou S, Szczesna K, Ochalek A, Kobolák J, Varga E, Nemes C, Chandrasekaran A, Rasmussen M, Cirera S, Hyttel P, Dinnyés A, Freude KK, Avci HX.

Stem Cells Int. 2016;2016:4937689. doi: 10.1155/2016/4937689. Epub 2015 Dec 21.

27.

Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro-engineering of their niche.

Kobolak J, Dinnyes A, Memic A, Khademhosseini A, Mobasheri A.

Methods. 2016 Apr 15;99:62-8. doi: 10.1016/j.ymeth.2015.09.016. Epub 2015 Sep 15. Review.

PMID:
26384580
28.

Cloning and characterization of rabbit POU5F1, SOX2, KLF4, C-MYC and NANOG pluripotency-associated genes.

Táncos Z, Bock I, Nemes C, Kobolák J, Dinnyés A.

Gene. 2015 Jul 25;566(2):148-57. doi: 10.1016/j.gene.2015.04.034. Epub 2015 Apr 18.

PMID:
25895477
29.

The crossroads between cancer stem cells and aging.

Santos Franco S, Raveh-Amit H, Kobolák J, Alqahtani MH, Mobasheri A, Dinnyes A.

BMC Cancer. 2015;15 Suppl 1:S1. doi: 10.1186/1471-2407-15-S1-S1. Epub 2015 Jan 15. Review.

30.

Autophagy is required for zebrafish caudal fin regeneration.

Varga M, Sass M, Papp D, Takács-Vellai K, Kobolak J, Dinnyés A, Klionsky DJ, Vellai T.

Cell Death Differ. 2014 Apr;21(4):547-56. doi: 10.1038/cdd.2013.175. Epub 2013 Dec 6.

31.

iTRAQ proteome analysis reflects a progressed differentiation state of epiblast derived versus inner cell mass derived murine embryonic stem cells.

Fröhlich T, Kösters M, Graf A, Wolf E, Kobolak J, Brochard V, Dinnyés A, Jouneau A, Arnold GJ.

J Proteomics. 2013 Sep 2;90:38-51. doi: 10.1016/j.jprot.2013.03.015. Epub 2013 Apr 18.

PMID:
23603003
32.

TYK2 kinase activity is required for functional type I interferon responses in vivo.

Prchal-Murphy M, Semper C, Lassnig C, Wallner B, Gausterer C, Teppner-Klymiuk I, Kobolak J, Müller S, Kolbe T, Karaghiosoff M, Dinnyés A, Rülicke T, Leitner NR, Strobl B, Müller M.

PLoS One. 2012;7(6):e39141. doi: 10.1371/journal.pone.0039141. Epub 2012 Jun 18.

33.

Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part II: gene regulation.

Kobolak J, Horsch M, Geissler S, Mamo S, Beckers J, Dinnyes A.

Cell Reprogram. 2012 Feb;14(1):68-78. doi: 10.1089/cell.2011.0057. Epub 2011 Dec 28.

34.

Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part I: cellular characterization.

Kobolak J, Mamo S, Rungsiwiwut R, Ujhelly O, Csonka E, Hadlaczky G, Dinnyes A.

Cell Reprogram. 2012 Feb;14(1):56-67. doi: 10.1089/cell.2011.0056. Epub 2011 Dec 28.

35.

Gene targeting and Calcium handling efficiencies in mouse embryonic stem cell lines.

Mamo S, Kobolak J, Borbíró I, Bíró T, Bock I, Dinnyes A.

World J Stem Cells. 2010 Dec 26;2(6):127-40. doi: 10.4252/wjsc.v2.i6.127.

36.

Generation of mouse embryonic stem cell lines from zona-free nuclear transfer embryos.

Kobolak J, Bodo S, Rungsiwiwut R, Meng Q, Adorjan M, Virutamasen P, Techakumphu M, Dinnyes A.

Cell Reprogram. 2010 Feb;12(1):105-13. doi: 10.1089/cell.2009.0040.

PMID:
20132018
37.

Promoter analysis of the rabbit POU5F1 gene and its expression in preimplantation stage embryos.

Kobolak J, Kiss K, Polgar Z, Mamo S, Rogel-Gaillard C, Tancos Z, Bock I, Baji AG, Tar K, Pirity MK, Dinnyes A.

BMC Mol Biol. 2009 Sep 4;10:88. doi: 10.1186/1471-2199-10-88.

38.

Gene expression profiles of vitrified in vivo derived 8-cell stage mouse embryos detected by high density oligonucleotide microarrays.

Mamo S, Bodo S, Kobolak J, Polgar Z, Tolgyesi G, Dinnyes A.

Mol Reprod Dev. 2006 Nov;73(11):1380-92.

PMID:
16897732
39.

Mouse embryonic stem cells express histidine decarboxylase and histamine H1 receptors.

Wiener Z, Tóth S, Gócza E, Kobolák J, Falus A.

Inflamm Res. 2003 Apr;52 Suppl 1:S53-4. No abstract available.

PMID:
12755409
40.

Activator effect of coinjected enhancers on the muscle-specific expression of promoters in zebrafish embryos.

Müller F, Williams DW, Kobolák J, Gauvry L, Goldspink G, Orbán L, Maclean N.

Mol Reprod Dev. 1997 Aug;47(4):404-12.

PMID:
9211424

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