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Items: 40


Oddballs in the Shaker family: Kv2-related regulatory subunits.

Kobertz WR.

J Gen Physiol. 2018 Dec 3;150(12):1599-1601. doi: 10.1085/jgp.201812251. Epub 2018 Nov 16. No abstract available.


The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death.

Velentzas PD, Zhang L, Das G, Chang TK, Nelson C, Kobertz WR, Baehrecke EH.

Dev Cell. 2018 Nov 5;47(3):281-293.e4. doi: 10.1016/j.devcel.2018.09.015. Epub 2018 Oct 11.


Palladium-Mediated Synthesis of a Near-Infrared Fluorescent K+ Sensor.

Bandara HMD, Hua Z, Zhang M, Pauff SM, Miller SC, Davie EAC, Kobertz WR.

J Org Chem. 2017 Aug 4;82(15):8199-8205. doi: 10.1021/acs.joc.7b00845. Epub 2017 Jul 14.


Fluorescent Visualization of Cellular Proton Fluxes.

Zhang L, Bellve K, Fogarty K, Kobertz WR.

Cell Chem Biol. 2016 Dec 22;23(12):1449-1457. doi: 10.1016/j.chembiol.2016.10.013. Epub 2016 Dec 1.


Erratum to: Mutant SOD1 protein increases Nav1.3 channel excitability.

Kubat Öktem E, Mruk K, Chang J, Akin A, Kobertz WR, Brown RH Jr.

J Biol Phys. 2016 Jun;42(3):371. No abstract available.


Mutant SOD1 protein increases Nav1.3 channel excitability.

Kubat Öktem E, Mruk K, Chang J, Akin A, Kobertz WR, Brown RH Jr.

J Biol Phys. 2016 Jun;42(3):351-70. doi: 10.1007/s10867-016-9411-x. Epub 2016 Apr 12. Erratum in: J Biol Phys. 2016 Jun;42(3):371.


Bioreactive Tethers.

Mruk K, Kobertz WR.

Adv Exp Med Biol. 2015;869:77-100. doi: 10.1007/978-1-4939-2845-3_5. Review.


LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms.

Aromolaran AS, Subramanyam P, Chang DD, Kobertz WR, Colecraft HM.

Cardiovasc Res. 2014 Dec 1;104(3):501-11. doi: 10.1093/cvr/cvu231. Epub 2014 Oct 24.


The middle X residue influences cotranslational N-glycosylation consensus site skipping.

Malaby HL, Kobertz WR.

Biochemistry. 2014 Aug 5;53(30):4884-93. doi: 10.1021/bi500681p. Epub 2014 Jul 25.


Calmodulation meta-analysis: predicting calmodulin binding via canonical motif clustering.

Mruk K, Farley BM, Ritacco AW, Kobertz WR.

J Gen Physiol. 2014 Jul;144(1):105-14. doi: 10.1085/jgp.201311140. Epub 2014 Jun 16.


Stoichiometry of the cardiac IKs complex.

Kobertz WR.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5065-6. doi: 10.1073/pnas.1403171111. Epub 2014 Mar 28. No abstract available.


Molecular determinants of co- and post-translational N-glycosylation of type I transmembrane peptides.

Malaby HL, Kobertz WR.

Biochem J. 2013 Aug 1;453(3):427-34. doi: 10.1042/BJ20130028.


Chemical derivatization and purification of peptide-toxins for probing ion channel complexes.

Hua Z, Kobertz WR.

Methods Mol Biol. 2013;995:19-30. doi: 10.1007/978-1-62703-345-9_2.


Structural insights into neuronal K+ channel-calmodulin complexes.

Mruk K, Shandilya SM, Blaustein RO, Schiffer CA, Kobertz WR.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13579-83. doi: 10.1073/pnas.1207606109. Epub 2012 Aug 6.


The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.

Gabriel L, Lvov A, Orthodoxou D, Rittenhouse AR, Kobertz WR, Melikian HE.

J Biol Chem. 2012 Sep 21;287(39):32354-66. Epub 2012 Jul 30.


Xenopus laevis oocytes infected with multi-drug-resistant bacteria: implications for electrical recordings.

O'Connell D, Mruk K, Rocheleau JM, Kobertz WR.

J Gen Physiol. 2011 Aug;138(2):271-7. doi: 10.1085/jgp.201110661.


Post-translational N-glycosylation of type I transmembrane KCNE1 peptides: implications for membrane protein biogenesis and disease.

Bas T, Gao GY, Lvov A, Chandrasekhar KD, Gilmore R, Kobertz WR.

J Biol Chem. 2011 Aug 12;286(32):28150-9. doi: 10.1074/jbc.M111.235168. Epub 2011 Jun 15.


O-glycosylation of the cardiac I(Ks) complex.

Chandrasekhar KD, Lvov A, Terrenoire C, Gao GY, Kass RS, Kobertz WR.

J Physiol. 2011 Aug 1;589(Pt 15):3721-30. doi: 10.1113/jphysiol.2011.211284. Epub 2011 Jun 13.


Nascent peptide side chains induce rearrangements in distinct locations of the ribosomal tunnel.

Lu J, Hua Z, Kobertz WR, Deutsch C.

J Mol Biol. 2011 Aug 12;411(2):499-510. doi: 10.1016/j.jmb.2011.05.038. Epub 2011 Jun 1.


Chemical control of metabolically-engineered voltage-gated K+ channels.

Hua Z, Lvov A, Morin TJ, Kobertz WR.

Bioorg Med Chem Lett. 2011 Sep 1;21(17):5021-4. doi: 10.1016/j.bmcl.2011.04.099. Epub 2011 Apr 28.


Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1.

Lvov A, Gage SD, Berrios VM, Kobertz WR.

J Gen Physiol. 2010 Jun;135(6):607-18. doi: 10.1085/jgp.200910386. Epub 2010 May 17.


Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes.

Mruk K, Kobertz WR.

PLoS One. 2009;4(1):e4236. doi: 10.1371/journal.pone.0004236. Epub 2009 Jan 21.


Chemical tools for K(+) channel biology.

Ahern CA, Kobertz WR.

Biochemistry. 2009 Jan 27;48(3):517-26. doi: 10.1021/bi8018515. Review.


Discovery of potent CLC chloride channel inhibitors.

Matulef K, Howery AE, Tan L, Kobertz WR, Du Bois J, Maduke M.

ACS Chem Biol. 2008 Jul 18;3(7):419-28. doi: 10.1021/cb800083a.


Tethering chemistry and K+ channels.

Morin TJ, Kobertz WR.

J Biol Chem. 2008 Sep 12;283(37):25105-9. doi: 10.1074/jbc.R800033200. Epub 2008 Jun 9. Review.


Counting membrane-embedded KCNE beta-subunits in functioning K+ channel complexes.

Morin TJ, Kobertz WR.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1478-82. doi: 10.1073/pnas.0710366105. Epub 2008 Jan 25.


KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels.

Rocheleau JM, Kobertz WR.

J Gen Physiol. 2008 Jan;131(1):59-68. Epub 2007 Dec 17.


Mapping the electrostatic potential within the ribosomal exit tunnel.

Lu J, Kobertz WR, Deutsch C.

J Mol Biol. 2007 Aug 31;371(5):1378-91. Epub 2007 Jun 19.


A derivatized scorpion toxin reveals the functional output of heteromeric KCNQ1-KCNE K+ channel complexes.

Morin TJ, Kobertz WR.

ACS Chem Biol. 2007 Jul 20;2(7):469-73. Epub 2007 Jun 29.


Secondary structure of a KCNE cytoplasmic domain.

Rocheleau JM, Gage SD, Kobertz WR.

J Gen Physiol. 2006 Dec;128(6):721-9.


KCNE1 subunits require co-assembly with K+ channels for efficient trafficking and cell surface expression.

Chandrasekhar KD, Bas T, Kobertz WR.

J Biol Chem. 2006 Dec 29;281(52):40015-23. Epub 2006 Oct 24.


KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels.

Gage SD, Kobertz WR.

J Gen Physiol. 2004 Dec;124(6):759-71.


Hanging gondola structure of the T1 domain in a voltage-gated K(+) channel.

Kobertz WR, Williams C, Miller C.

Biochemistry. 2000 Aug 29;39(34):10347-52.


Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease.

Kuraoka I, Kobertz WR, Ariza RR, Biggerstaff M, Essigmann JM, Wood RD.

J Biol Chem. 2000 Aug 25;275(34):26632-6.


RuvAB-mediated branch migration does not involve extensive DNA opening within the RuvB hexamer.

George H, Kuraoka I, Nauman DA, Kobertz WR, Wood RD, West SC.

Curr Biol. 2000 Jan 27;10(2):103-6.


K+ channels lacking the 'tetramerization' domain: implications for pore structure.

Kobertz WR, Miller C.

Nat Struct Biol. 1999 Dec;6(12):1122-5.


Mass spectral identification and positional mapping of aflatoxin B1-guanine adducts in oligonucleotides.

Marzilli LA, Wang D, Kobertz WR, Essigmann JM, Vouros P.

J Am Soc Mass Spectrom. 1998 Jul;9(7):676-82.


An Efficient Synthesis of a Furan-Side Furocoumarin Thymidine Monoadduct.

Kobertz WR, Essigmann JM.

J Org Chem. 1997 Apr 18;62(8):2630-2632. No abstract available.


C-Glycosyl Aldehydes: Synthons for C-Linked Disaccharides.

Kobertz WR, Bertozzi CR, Bednarski MD.

J Org Chem. 1996 Mar 8;61(5):1894-1897. No abstract available.


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