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Items: 1 to 50 of 89

1.

Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.

Dutta P, Perez MR, Lee J, Kang Y, Pratt M, Salzillo TC, Weygand J, Zacharias NM, Gammon ST, Koay EJ, Kim M, McAllister F, Sen S, Maitra A, Piwnica-Worms D, Fleming JB, Bhattacharya PK.

J Proteome Res. 2019 Jul 5;18(7):2826-2834. doi: 10.1021/acs.jproteome.9b00132. Epub 2019 Jun 4.

PMID:
31120258
2.

Novel EUS-guided brachytherapy treatment of pancreatic cancer with phosphorus-32 microparticles: first United States experience.

Bhutani MS, Cazacu IM, Luzuriaga Chavez AA, Singh BS, Wong FCL, Erwin WD, Tamm EP, Mathew GG, Le DB, Koay EJ, Taniguchi CM, Minsky BD, Pant S, Tzeng CD, Koong AC, Varadhachary GR, Katz MHG, Wolff RA, Fogelman DR, Herman JM.

VideoGIE. 2019 Apr 29;4(5):223-225. doi: 10.1016/j.vgie.2019.02.009. eCollection 2019 May. No abstract available.

3.

Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.

Fujimoto TN, Colbert LE, Huang Y, Molkentine JM, Deorukhkar A, Baseler L, de la Cruz Bonilla M, Yu M, Lin D, Gupta S, Cabeceiras PK, Kingsley CV, Tailor RC, Sawakuchi GO, Koay EJ, Piwnica-Worms H, Maitra A, Taniguchi CM.

Cancer Res. 2019 May 1;79(9):2327-2338. doi: 10.1158/0008-5472.CAN-18-1785.

PMID:
31043430
4.

Cancer overdiagnosis: a biological challenge and clinical dilemma.

Srivastava S, Koay EJ, Borowsky AD, De Marzo AM, Ghosh S, Wagner PD, Kramer BS.

Nat Rev Cancer. 2019 Jun;19(6):349-358. doi: 10.1038/s41568-019-0142-8. Review.

PMID:
31024081
5.

Effect of setup and inter-fraction anatomical changes on the accumulated dose in CT-guided breath-hold intensity modulated proton therapy of liver malignancies.

Yang Z, Chang Y, Brock KK, Cazoulat G, Koay EJ, Koong AC, Herman JM, Park PC, Poenisch F, Li Q, Yang K, Wu G, Anderson B, Ohrt AN, Li Y, Zhu XR, Zhang X, Li H.

Radiother Oncol. 2019 May;134:101-109. doi: 10.1016/j.radonc.2019.01.028. Epub 2019 Feb 6.

PMID:
31005203
6.

Proton beam therapy outcomes for localized unresectable hepatocellular carcinoma.

Chadha AS, Gunther JR, Hsieh CE, Aliru M, Mahadevan LS, Venkatesulu BP, Crane CH, Das P, Herman JM, Koay EJ, Taniguchi C, Holliday EB, Minsky BD, Suh Y, Park P, Sawakuchi G, Beddar S, Odisio BC, Gupta S, Loyer E, Kaur H, Raghav K, Javle MM, Kaseb AO, Krishnan S.

Radiother Oncol. 2019 Apr;133:54-61. doi: 10.1016/j.radonc.2018.10.041. Epub 2019 Jan 16.

PMID:
30935582
7.

Early Detection of Pancreatic Cancer: Opportunities and Challenges.

Singhi AD, Koay EJ, Chari ST, Maitra A.

Gastroenterology. 2019 May;156(7):2024-2040. doi: 10.1053/j.gastro.2019.01.259. Epub 2019 Feb 2. Review.

8.

Protons versus Photons for Unresectable Hepatocellular Carcinoma: Liver Decompensation and Overall Survival.

Sanford NN, Pursley J, Noe B, Yeap BY, Goyal L, Clark JW, Allen JN, Blaszkowsky LS, Ryan DP, Ferrone CR, Tanabe KK, Qadan M, Crane CH, Koay EJ, Eyler C, DeLaney TF, Zhu AX, Wo JY, Grassberger C, Hong TS.

Int J Radiat Oncol Biol Phys. 2019 Jan 23. pii: S0360-3016(19)30158-0. doi: 10.1016/j.ijrobp.2019.01.076. [Epub ahead of print]

PMID:
30684667
9.

Chemoresistance Transmission via Exosome-Mediated EphA2 Transfer in Pancreatic Cancer.

Fan J, Wei Q, Koay EJ, Liu Y, Ning B, Bernard PW, Zhang N, Han H, Katz MH, Zhao Z, Hu Y.

Theranostics. 2018 Nov 13;8(21):5986-5994. doi: 10.7150/thno.26650. eCollection 2018.

10.

Correction function for accuracy improvement of the Composite Smeared Finite Element for diffusive transport in biological tissue systems.

Milosevic M, Simic V, Milicevic B, Koay EJ, Ferrari M, Ziemys A, Kojic M.

Comput Methods Appl Mech Eng. 2018 Aug 15;338:97-116. doi: 10.1016/j.cma.2018.04.012. Epub 2018 Apr 22.

PMID:
30555187
11.

Pretreatment plasma HGF as potential biomarker for susceptibility to radiation-induced liver dysfunction after radiotherapy.

Hong TS, Grassberger C, Yeap BY, Jiang W, Wo JY, Goyal L, Clark JW, Crane CH, Koay EJ, Dima S, Eyler CE, Popescu I, DeLaney TF, Zhu AX, Duda DG.

NPJ Precis Oncol. 2018 Oct 18;2:22. doi: 10.1038/s41698-018-0065-y. eCollection 2018.

12.

Dose escalation for locally advanced pancreatic cancer: How high can we go?

Colbert LE, Rebueno N, Moningi S, Beddar S, Sawakuchi GO, Herman JM, Koong AC, Das P, Holliday EB, Koay EJ, Taniguchi CM.

Adv Radiat Oncol. 2018 Oct 23;3(4):693-700. doi: 10.1016/j.adro.2018.07.008. eCollection 2018 Oct-Dec.

13.

First-Line Gemcitabine and Nab-Paclitaxel Chemotherapy for Localized Pancreatic Ductal Adenocarcinoma.

Gulhati P, Prakash L, Katz MHG, Wang X, Javle M, Shroff R, Fogelman D, Lee JE, Tzeng CD, Lee JH, Weston B, Tamm E, Bhosale P, Koay EJ, Maitra A, Wang H, Wolff RA, Varadhachary GR.

Ann Surg Oncol. 2019 Feb;26(2):619-627. doi: 10.1245/s10434-018-6807-9. Epub 2018 Oct 15.

PMID:
30324485
14.

Radiation-Induced Liver Disease and Modern Radiotherapy.

Koay EJ, Owen D, Das P.

Semin Radiat Oncol. 2018 Oct;28(4):321-331. doi: 10.1016/j.semradonc.2018.06.007. Review.

PMID:
30309642
15.

Lung tumor segmentation methods: Impact on the uncertainty of radiomics features for non-small cell lung cancer.

Owens CA, Peterson CB, Tang C, Koay EJ, Yu W, Mackin DS, Li J, Salehpour MR, Fuentes DT, Court LE, Yang J.

PLoS One. 2018 Oct 4;13(10):e0205003. doi: 10.1371/journal.pone.0205003. eCollection 2018.

16.

Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma.

Li X, Lee Y, Kang Y, Dai B, Perez MR, Pratt M, Koay EJ, Kim M, Brekken RA, Fleming JB.

Cell Death Differ. 2019 Jan;26(2):382-393. doi: 10.1038/s41418-018-0207-3. Epub 2018 Oct 3.

PMID:
30283082
17.

Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer.

Bernard V, Kim DU, San Lucas FA, Castillo J, Allenson K, Mulu FC, Stephens BM, Huang J, Semaan A, Guerrero PA, Kamyabi N, Zhao J, Hurd MW, Koay EJ, Taniguchi CM, Herman JM, Javle M, Wolff R, Katz M, Varadhachary G, Maitra A, Alvarez HA.

Gastroenterology. 2019 Jan;156(1):108-118.e4. doi: 10.1053/j.gastro.2018.09.022. Epub 2018 Sep 19.

18.

Current and emerging radiotherapy strategies for pancreatic adenocarcinoma: stereotactic, intensity modulated and particle radiotherapy.

Ng SP, Koay EJ.

Ann Pancreat Cancer. 2018 Aug;1. pii: 22. doi: 10.21037/apc.2018.07.03. Epub 2018 Aug 13.

19.

Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making?

Sharib JM, Fonseca AL, Swords DS, Jaradeh K, Bracci PM, Firpo MA, Hatcher S, Scaife CL, Wang H, Kim GE, Mulvihill SJ, Maitra A, Koay EJ, Kirkwood KS.

Surgery. 2018 Dec;164(6):1178-1184. doi: 10.1016/j.surg.2018.07.014. Epub 2018 Aug 28.

PMID:
30170819
20.

Dose escalation of radiotherapy in unresectable extrahepatic cholangiocarcinoma.

Elganainy D, Holliday EB, Taniguchi CM, Smith GL, Shroff R, Javle M, Raghav K, Kaseb A, Aloia TA, Vauthey JN, Tzeng CD, Herman JM, Koong AC, Krishnan SX, Minsky BD, Crane CH, Das P, Koay EJ.

Cancer Med. 2018 Oct;7(10):4880-4892. doi: 10.1002/cam4.1734. Epub 2018 Aug 27.

21.

Hyperfractionated abdominal reirradiation for gastrointestinal malignancies.

Hunt A, Das P, Minsky BD, Koay EJ, Krishnan S, Herman JM, Taniguchi C, Koong A, Smith GL, Holliday EB.

Radiat Oncol. 2018 Aug 7;13(1):143. doi: 10.1186/s13014-018-1084-0.

22.

A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma.

Koay EJ, Lee Y, Cristini V, Lowengrub JS, Kang Y, Lucas FAS, Hobbs BP, Ye R, Elganainy D, Almahariq M, Amer AM, Chatterjee D, Yan H, Park PC, Rios Perez MV, Li D, Garg N, Reiss KA, Yu S, Chauhan A, Zaid M, Nikzad N, Wolff RA, Javle M, Varadhachary GR, Shroff RT, Das P, Lee JE, Ferrari M, Maitra A, Taniguchi CM, Kim MP, Crane CH, Katz MH, Wang H, Bhosale P, Tamm EP, Fleming JB.

Clin Cancer Res. 2018 Dec 1;24(23):5883-5894. doi: 10.1158/1078-0432.CCR-17-3668. Epub 2018 Aug 6.

PMID:
30082477
23.

Comparing Ablative Modalities for Hepatocellular Carcinoma: Cautions in Interpreting Big Data.

Smith GL, Das P, Herman JM, Koay EJ, Koong AC, Grossberg A, Ludmir E.

J Clin Oncol. 2018 Aug 20;36(24):2565-2566. doi: 10.1200/JCO.2018.78.5428. Epub 2018 Jun 26. No abstract available.

PMID:
29945520
24.

Differential Association Between Circulating Lymphocyte Populations With Outcome After Radiation Therapy in Subtypes of Liver Cancer.

Grassberger C, Hong TS, Hato T, Yeap BY, Wo JY, Tracy M, Bortfeld T, Wolfgang JA, Eyler CE, Goyal L, Clark JW, Crane CH, Koay EJ, Cobbold M, DeLaney TF, Jain RK, Zhu AX, Duda DG.

Int J Radiat Oncol Biol Phys. 2018 Aug 1;101(5):1222-1225. doi: 10.1016/j.ijrobp.2018.04.026. Epub 2018 Apr 17.

PMID:
29859792
25.

Multiscale smeared finite element model for mass transport in biological tissue: From blood vessels to cells and cellular organelles.

Kojic M, Milosevic M, Simic V, Koay EJ, Kojic N, Ziemys A, Ferrari M.

Comput Biol Med. 2018 Aug 1;99:7-23. doi: 10.1016/j.compbiomed.2018.05.022. Epub 2018 May 21.

PMID:
29807251
26.

SMAD4 Gene Mutation Renders Pancreatic Cancer Resistance to Radiotherapy through Promotion of Autophagy.

Wang F, Xia X, Yang C, Shen J, Mai J, Kim HC, Kirui D, Kang Y, Fleming JB, Koay EJ, Mitra S, Ferrari M, Shen H.

Clin Cancer Res. 2018 Jul 1;24(13):3176-3185. doi: 10.1158/1078-0432.CCR-17-3435. Epub 2018 Mar 30.

27.

Definitive radiation therapy for hepatocellular carcinoma with portal vein tumor thrombus.

Holliday EB, Tao R, Brownlee Z, Das P, Krishnan S, Taniguchi C, Minsky BD, Herman JM, Kaseb A, Raghav K, Conrad C, Vauthey JN, Aloia TA, Chun YS, Crane CH, Koay EJ.

Clin Transl Radiat Oncol. 2017 Jun 7;4:39-45. doi: 10.1016/j.ctro.2017.04.003. eCollection 2017 Jun.

28.

Pancreatic gross tumor volume contouring on computed tomography (CT) compared with magnetic resonance imaging (MRI): Results of an international contouring conference.

Hall WA, Heerkens HD, Paulson ES, Meijer GJ, Kotte AN, Knechtges P, Parikh PJ, Bassetti MF, Lee P, Aitken KL, Palta M, Myrehaug S, Koay EJ, Portelance L, Ben-Josef E, Erickson BA.

Pract Radiat Oncol. 2018 Mar - Apr;8(2):107-115. doi: 10.1016/j.prro.2017.11.005. Epub 2017 Nov 29.

PMID:
29426692
29.

Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk.

Fonseca AL, Kirkwood K, Kim MP, Maitra A, Koay EJ.

Pancreas. 2018 Mar;47(3):272-279. doi: 10.1097/MPA.0000000000000999. Review.

30.

Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer.

Tang C, Hobbs B, Amer A, Li X, Behrens C, Canales JR, Cuentas EP, Villalobos P, Fried D, Chang JY, Hong DS, Welsh JW, Sepesi B, Court L, Wistuba II, Koay EJ.

Sci Rep. 2018 Jan 31;8(1):1922. doi: 10.1038/s41598-018-20471-5.

31.

Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy.

Amer AM, Zaid M, Chaudhury B, Elganainy D, Lee Y, Wilke CT, Cloyd J, Wang H, Maitra A, Wolff RA, Varadhachary G, Overman MJ, Lee JE, Fleming JB, Tzeng CW, Katz MH, Holliday EB, Krishnan S, Minsky BD, Herman JM, Taniguchi CM, Das P, Crane CH, Le O, Bhosale P, Tamm EP, Koay EJ.

Cancer. 2018 Apr 15;124(8):1701-1709. doi: 10.1002/cncr.31251. Epub 2018 Jan 25.

32.

Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy.

Zhao J, Wang H, Hsiao CH, Chow DS, Koay EJ, Kang Y, Wen X, Huang Q, Ma Y, Bankson JA, Ullrich SE, Overwijk W, Maitra A, Piwnica-Worms D, Fleming JB, Li C.

Biomaterials. 2018 Mar;159:215-228. doi: 10.1016/j.biomaterials.2018.01.014. Epub 2018 Jan 9.

33.

Short course radiation as a component of definitive multidisciplinary treatment for select patients with metastatic rectal adenocarcinoma.

Holliday EB, Hunt A, You YN, Chang GJ, Skibber JM, Rodriguez-Bigas MA, Bednarski BK, Eng C, Koay EJ, Minsky BD, Taniguchi C, Krishnan S, Herman JM, Das P.

J Gastrointest Oncol. 2017 Dec;8(6):990-997. doi: 10.21037/jgo.2017.09.02.

34.

Severe lymphopenia during neoadjuvant chemoradiation for esophageal cancer: A propensity matched analysis of the relative risk of proton versus photon-based radiation therapy.

Shiraishi Y, Fang P, Xu C, Song J, Krishnan S, Koay EJ, Mehran RJ, Hofstetter WL, Blum-Murphy M, Ajani JA, Komaki R, Minsky B, Mohan R, Hsu CC, Hobbs BP, Lin SH.

Radiother Oncol. 2018 Jul;128(1):154-160. doi: 10.1016/j.radonc.2017.11.028. Epub 2017 Dec 14.

35.

Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer.

Yu W, Tang C, Hobbs BP, Li X, Koay EJ, Wistuba II, Sepesi B, Behrens C, Rodriguez Canales J, Parra Cuentas ER, Erasmus JJ, Court LE, Chang JY.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1090-1097. doi: 10.1016/j.ijrobp.2017.10.046. Epub 2017 Nov 15.

PMID:
29246722
36.

A composite smeared finite element for mass transport in capillary systems and biological tissue.

Kojic M, Milosevic M, Simic V, Koay EJ, Fleming JB, Nizzero S, Kojic N, Ziemys A, Ferrari M.

Comput Methods Appl Mech Eng. 2017 Sep 1;324:413-437. doi: 10.1016/j.cma.2017.06.019. Epub 2017 Jun 29.

37.

Melanoma brain metastases harboring BRAF V600K or NRAS mutations are associated with an increased local failure rate following conventional therapy.

Fang P, Boehling NS, Koay EJ, Bucheit AD, Jakob JA, Settle SH, Brown PD, Davies MA, Sulman EP.

J Neurooncol. 2018 Mar;137(1):67-75. doi: 10.1007/s11060-017-2695-2. Epub 2017 Dec 2.

PMID:
29198052
38.

Imaging findings of recurrent pancreatic cancer following resection.

Javadi S, Karbasian N, Bhosale P, de Castro Faria S, Le O, Katz MH, Koay EJ, Tamm EP.

Abdom Radiol (NY). 2018 Feb;43(2):489-496. doi: 10.1007/s00261-017-1397-8. Review.

PMID:
29198001
39.

Dose escalation with an IMRT technique in 15 to 28 fractions is better tolerated than standard doses of 3DCRT for LAPC.

Colbert LE, Moningi S, Chadha A, Amer A, Lee Y, Wolff RA, Varadhachary G, Fleming J, Katz M, Das P, Krishnan S, Koay EJ, Park P, Crane CH, Taniguchi CM.

Adv Radiat Oncol. 2017 Mar 18;2(3):403-415. doi: 10.1016/j.adro.2017.02.004. eCollection 2017 Jul-Sep.

40.

The role of imaging in the clinical practice of radiation oncology for pancreatic cancer.

Koay EJ, Hall W, Park PC, Erickson B, Herman JM.

Abdom Radiol (NY). 2018 Feb;43(2):393-403. doi: 10.1007/s00261-017-1373-3. Review.

41.

A hindsight reflection on the clinical studies of poly(l-glutamic acid)-paclitaxel.

Zhao J, Koay EJ, Li T, Wen X, Li C.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 May;10(3):e1497. doi: 10.1002/wnan.1497. Epub 2017 Sep 11. Review.

PMID:
28895304
42.

Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma Microsamples for Diagnosis and Treatment Monitoring.

Liang K, Liu F, Fan J, Sun D, Liu C, Lyon CJ, Bernard DW, Li Y, Yokoi K, Katz MH, Koay EJ, Zhao Z, Hu Y.

Nat Biomed Eng. 2017;1. pii: 0021. doi: 10.1038/s41551-016-0021. Epub 2017 Feb 6.

43.

Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas.

Katz MHG, Ou FS, Herman JM, Ahmad SA, Wolpin B, Marsh R, Behr S, Shi Q, Chuong M, Schwartz LH, Frankel W, Collisson E, Koay EJ, Hubbard JM, Leenstra JL, Meyerhardt J, O'Reilly E; Alliance for Clinical Trials on Oncology.

BMC Cancer. 2017 Jul 27;17(1):505. doi: 10.1186/s12885-017-3441-z.

44.

Association of Clinical Factors With a Major Pathologic Response Following Preoperative Therapy for Pancreatic Ductal Adenocarcinoma.

Cloyd JM, Wang H, Egger ME, Tzeng CD, Prakash LR, Maitra A, Varadhachary GR, Shroff R, Javle M, Fogelman D, Wolff RA, Overman MJ, Koay EJ, Das P, Herman JM, Kim MP, Vauthey JN, Aloia TA, Fleming JB, Lee JE, Katz MHG.

JAMA Surg. 2017 Nov 1;152(11):1048-1056. doi: 10.1001/jamasurg.2017.2227.

45.

Gemcitabine enhances the transport of nanovector-albumin-bound paclitaxel in gemcitabine-resistant pancreatic ductal adenocarcinoma.

Borsoi C, Leonard F, Lee Y, Zaid M, Elganainy D, Alexander JF, Kai M, Liu YT, Kang Y, Liu X, Koay EJ, Ferrari M, Godin B, Yokoi K.

Cancer Lett. 2017 Sep 10;403:296-304. doi: 10.1016/j.canlet.2017.06.026. Epub 2017 Jul 4.

46.

Natural History of T1N0M0 Hepatocellular Carcinoma: Large-Scale Study in the United States.

Al-Shamsi HO, Abdel-Wahab R, Hassan MM, Shalaby AS, Dahbour I, Lacin S, Mahvash A, Odisio BC, Murthy R, Avritscher R, Abdelsalam ME, Rashid A, Vauthey JN, Aloia TA, Conrad C, Chun YS, Krishnan S, Das P, Koay EJ, Amin HM, Yao JC, Kaseb AO.

Oncology. 2017;93(4):233-242. doi: 10.1159/000455957. Epub 2017 Jul 6.

PMID:
28683459
47.

Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth.

Li X, Kang Y, Roife D, Lee Y, Pratt M, Perez MR, Dai B, Koay EJ, Fleming JB.

Oncogene. 2017 Sep 21;36(38):5432-5438. doi: 10.1038/onc.2017.125. Epub 2017 May 22.

48.

Management of unresectable intrahepatic cholangiocarcinoma: how do we decide among the various liver-directed treatments?

Koay EJ, Odisio BC, Javle M, Vauthey JN, Crane CH.

Hepatobiliary Surg Nutr. 2017 Apr;6(2):105-116. doi: 10.21037/hbsn.2017.01.16. Review.

49.

Influence of Preoperative Therapy on Short- and Long-Term Outcomes of Patients with Adenocarcinoma of the Ampulla of Vater.

Cloyd JM, Wang H, Overman M, Zhao J, Denbo J, Prakash L, Kim MP, Shroff R, Javle M, Varadhachary GR, Fogelman D, Wolff RA, Koay EJ, Das P, Maitra A, Aloia TA, Vauthey JN, Fleming JB, Lee JE, Katz MHG.

Ann Surg Oncol. 2017 Jul;24(7):2031-2039. doi: 10.1245/s10434-017-5777-7. Epub 2017 Jan 25.

PMID:
28124275
50.

Recommendations for MRI-based contouring of gross tumor volume and organs at risk for radiation therapy of pancreatic cancer.

Heerkens HD, Hall WA, Li XA, Knechtges P, Dalah E, Paulson ES, van den Berg CA, Meijer GJ, Koay EJ, Crane CH, Aitken K, van Vulpen M, Erickson BA.

Pract Radiat Oncol. 2017 Mar - Apr;7(2):126-136. doi: 10.1016/j.prro.2016.10.006. Epub 2016 Oct 17.

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