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Items: 1 to 50 of 52

1.

Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.

Hrckulak D, Janeckova L, Lanikova L, Kriz V, Horazna M, Babosova O, Vojtechova M, Galuskova K, Sloncova E, Korinek V.

Genes (Basel). 2018 Sep 1;9(9). pii: E439. doi: 10.3390/genes9090439.

2.

Tcf7L2 is essential for neurogenesis in the developing mouse neocortex.

Chodelkova O, Masek J, Korinek V, Kozmik Z, Machon O.

Neural Dev. 2018 May 11;13(1):8. doi: 10.1186/s13064-018-0107-8.

3.

Author Correction: The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.

Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K.

Sci Rep. 2018 Apr 5;8(1):5762. doi: 10.1038/s41598-018-22650-w.

4.

HIC1 links retinoic acid signalling to group 3 innate lymphoid cell-dependent regulation of intestinal immunity and homeostasis.

Burrows K, Antignano F, Chenery A, Bramhall M, Korinek V, Underhill TM, Zaph C.

PLoS Pathog. 2018 Feb 22;14(2):e1006869. doi: 10.1371/journal.ppat.1006869. eCollection 2018 Feb.

5.

Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells.

Kriz V, Korinek V.

Genes (Basel). 2018 Jan 8;9(1). pii: E20. doi: 10.3390/genes9010020. Review.

6.

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.

Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K.

Sci Rep. 2017 Aug 24;7(1):9322. doi: 10.1038/s41598-017-09490-w. Erratum in: Sci Rep. 2018 Apr 5;8(1):5762.

7.

Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.

Kriz V, Krausova M, Buresova P, Dobes J, Hrckulak D, Babosova O, Svec J, Korinek V.

Transgenic Res. 2017 Oct;26(5):689-701. doi: 10.1007/s11248-017-0027-0. Epub 2017 Jun 20.

8.

HIC1 loss promotes prostate cancer metastasis by triggering epithelial-mesenchymal transition.

Hao M, Li Y, Wang J, Qin J, Wang Y, Ding Y, Jiang M, Sun X, Zu L, Chang K, Lin G, Du J, Korinek V, Ye DW, Wang J.

J Pathol. 2017 Aug;242(4):409-420. doi: 10.1002/path.4913. Epub 2017 Jun 13.

PMID:
28466555
9.

The transcriptional repressor HIC1 regulates intestinal immune homeostasis.

Burrows K, Antignano F, Bramhall M, Chenery A, Scheer S, Korinek V, Underhill TM, Zaph C.

Mucosal Immunol. 2017 Nov;10(6):1518-1528. doi: 10.1038/mi.2017.17. Epub 2017 Mar 22.

PMID:
28327618
10.

Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera.

Lanikova L, Babosova O, Swierczek S, Wang L, Wheeler DA, Divoky V, Korinek V, Prchal JT.

Blood. 2016 Nov 3;128(18):2266-2270. Epub 2016 Sep 19. No abstract available.

11.

Manipulating Wnt signaling at different subcellular levels affects the fate of neonatal neural stem/progenitor cells.

Kriska J, Honsa P, Dzamba D, Butenko O, Kolenicova D, Janeckova L, Nahacka Z, Andera L, Kozmik Z, Taketo MM, Korinek V, Anderova M.

Brain Res. 2016 Nov 15;1651:73-87. doi: 10.1016/j.brainres.2016.09.026. Epub 2016 Sep 19.

PMID:
27659965
12.

Revision of the Old World Daphnia (Ctenodaphnia) similis group Cladocera: Daphniidae).

Popova EV, Petrusek A, Kořínek V, Mergeay J, Bekker EI, Karabanov DP, Galimov YR, Neretina TV, Taylor DJ, Kotov AA.

Zootaxa. 2016 Sep 2;4161(1):1-40. doi: 10.11646/zootaxa.4161.1.1.

PMID:
27615909
13.

TCF/LEF Transcription Factors: An Update from the Internet Resources.

Hrckulak D, Kolar M, Strnad H, Korinek V.

Cancers (Basel). 2016 Jul 20;8(7). pii: E70. doi: 10.3390/cancers8070070. Review.

14.

Tcf7l1 protects the anterior neural fold from adopting the neural crest fate.

Mašek J, Machoň O, Kořínek V, Taketo MM, Kozmik Z.

Development. 2016 Jun 15;143(12):2206-16. doi: 10.1242/dev.132357.

15.

HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.

Janeckova L, Kolar M, Svec J, Lanikova L, Pospichalova V, Baloghova N, Vojtechova M, Sloncova E, Strnad H, Korinek V.

Transl Oncol. 2016 Apr;9(2):99-107. doi: 10.1016/j.tranon.2016.01.005. Epub 2016 Mar 4.

16.

Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity.

Janeckova L, Fafilek B, Krausova M, Horazna M, Vojtechova M, Alberich-Jorda M, Sloncova E, Galuskova K, Sedlacek R, Anderova M, Korinek V.

Genesis. 2016 Mar;54(3):101-14. doi: 10.1002/dvg.22922. Epub 2016 Feb 16.

17.

Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.

Hayakawa Y, Ariyama H, Stancikova J, Sakitani K, Asfaha S, Renz BW, Dubeykovskaya ZA, Shibata W, Wang H, Westphalen CB, Chen X, Takemoto Y, Kim W, Khurana SS, Tailor Y, Nagar K, Tomita H, Hara A, Sepulveda AR, Setlik W, Gershon MD, Saha S, Ding L, Shen Z, Fox JG, Friedman RA, Konieczny SF, Worthley DL, Korinek V, Wang TC.

Cancer Cell. 2015 Dec 14;28(6):800-814. doi: 10.1016/j.ccell.2015.10.003. Epub 2015 Nov 12.

18.

MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function.

Brauer R, Tureckova J, Kanchev I, Khoylou M, Skarda J, Prochazka J, Spoutil F, Beck IM, Zbodakova O, Kasparek P, Korinek V, Chalupsky K, Karhu T, Herzig KH, Hajduch M, Gregor M, Sedlacek R.

Mucosal Immunol. 2016 Jul;9(4):974-85. doi: 10.1038/mi.2015.117. Epub 2015 Nov 11.

PMID:
26555704
19.

HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.

Janeckova L, Pospichalova V, Fafilek B, Vojtechova M, Tureckova J, Dobes J, Dubuissez M, Leprince D, Baloghova N, Horazna M, Hlavata A, Stancikova J, Sloncova E, Galuskova K, Strnad H, Korinek V.

Mol Cancer Res. 2015 Jul;13(7):1139-48. doi: 10.1158/1541-7786.MCR-15-0033. Epub 2015 May 1.

20.

NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling.

Stancikova J, Krausova M, Kolar M, Fafilek B, Svec J, Sedlacek R, Neroldova M, Dobes J, Horazna M, Janeckova L, Vojtechova M, Oliverius M, Jirsa M, Korinek V.

Cell Signal. 2015 Feb;27(2):245-56. doi: 10.1016/j.cellsig.2014.11.008. Epub 2014 Nov 14.

21.

Efficient gene targeting of the Rosa26 locus in mouse zygotes using TALE nucleases.

Kasparek P, Krausova M, Haneckova R, Kriz V, Zbodakova O, Korinek V, Sedlacek R.

FEBS Lett. 2014 Nov 3;588(21):3982-8. doi: 10.1016/j.febslet.2014.09.014. Epub 2014 Sep 18.

22.

Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice.

Tumova L, Pombinho AR, Vojtechova M, Stancikova J, Gradl D, Krausova M, Sloncova E, Horazna M, Kriz V, Machonova O, Jindrich J, Zdrahal Z, Bartunek P, Korinek V.

Mol Cancer Ther. 2014 Apr;13(4):812-22. doi: 10.1158/1535-7163.MCT-13-0625. Epub 2014 Feb 19.

23.

Wnt signaling in adult intestinal stem cells and cancer.

Krausova M, Korinek V.

Cell Signal. 2014 Mar;26(3):570-9. doi: 10.1016/j.cellsig.2013.11.032. Epub 2013 Dec 2. Review.

24.

ADAM10/17-dependent release of soluble c-Met correlates with hepatocellular damage.

Chalupský K, Kanchev I, Žbodáková O, Buryová H, Jiroušková M, Kořínek V, Gregor M, Sedláček R.

Folia Biol (Praha). 2013;59(2):76-86.

25.

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M.

Cancer Res. 2013 May 15;73(10):3132-44. doi: 10.1158/0008-5472.CAN-12-4562. Epub 2013 Mar 28.

26.

Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.

Fafilek B, Krausova M, Vojtechova M, Pospichalova V, Tumova L, Sloncova E, Huranova M, Stancikova J, Hlavata A, Svec J, Sedlacek R, Luksan O, Oliverius M, Voska L, Jirsa M, Paces J, Kolar M, Krivjanska M, Klimesova K, Tlaskalova-Hogenova H, Korinek V.

Gastroenterology. 2013 Feb;144(2):381-91. doi: 10.1053/j.gastro.2012.10.048. Epub 2012 Nov 7.

PMID:
23142137
27.

Signal transduction pathways participating in homeostasis and malignant transformation of the intestinal tissue.

Krausova M, Korinek V.

Neoplasma. 2012;59(6):708-18. doi: 10.4149/neo_2012_090. Review.

PMID:
22862172
28.

A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S.

Cancer Res. 2012 Jun 1;72(11):2822-32. doi: 10.1158/0008-5472.CAN-11-3336. Epub 2012 Mar 22.

29.

Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.

Pospichalova V, Tureckova J, Fafilek B, Vojtechova M, Krausova M, Lukas J, Sloncova E, Takacova S, Divoky V, Leprince D, Plachy J, Korinek V.

Genesis. 2011 Mar;49(3):142-51. doi: 10.1002/dvg.20719.

PMID:
21309068
30.

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling.

Doubravska L, Krausova M, Gradl D, Vojtechova M, Tumova L, Lukas J, Valenta T, Pospichalova V, Fafilek B, Plachy J, Sebesta O, Korinek V.

Cell Signal. 2011 May;23(5):837-48. doi: 10.1016/j.cellsig.2011.01.007. Epub 2011 Jan 16.

PMID:
21244856
31.

Focal adhesion kinase functions as an akt downstream target in migration of colorectal cancer cells.

Turecková J, Vojtechová M, Krausová M, Sloncová E, Korínek V.

Transl Oncol. 2009 Dec;2(4):281-90.

32.

Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.

Fujimura N, Taketo MM, Mori M, Korinek V, Kozmik Z.

Dev Biol. 2009 Oct 1;334(1):31-45. doi: 10.1016/j.ydbio.2009.07.002. Epub 2009 Jul 9.

33.

Dazap2 modulates transcription driven by the Wnt effector TCF-4.

Lukas J, Mazna P, Valenta T, Doubravska L, Pospichalova V, Vojtechova M, Fafilek B, Ivanek R, Plachy J, Novak J, Korinek V.

Nucleic Acids Res. 2009 May;37(9):3007-20. doi: 10.1093/nar/gkp179. Epub 2009 Mar 20.

34.

Wnt-expressing rat embryonic fibroblasts suppress Apo2L/TRAIL-induced apoptosis of human leukemia cells.

Doubravská L, Símová S, Cermak L, Valenta T, Korínek V, Andera L.

Apoptosis. 2008 Apr;13(4):573-87. doi: 10.1007/s10495-008-0191-z. Epub 2008 Mar 18.

PMID:
18347988
35.

Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad.

Asahina M, Valenta T, Silhankova M, Korinek V, Jindra M.

Dev Cell. 2006 Aug;11(2):203-11.

36.

HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.

Valenta T, Lukas J, Doubravska L, Fafilek B, Korinek V.

EMBO J. 2006 Jun 7;25(11):2326-37. Epub 2006 May 25.

38.

Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo.

Weber T, Lu M, Andera L, Lahm H, Gellert N, Fariss MW, Korinek V, Sattler W, Ucker DS, Terman A, Schröder A, Erl W, Brunk UT, Coffey RJ, Weber C, Neuzil J.

Clin Cancer Res. 2002 Mar;8(3):863-9.

39.

Developmentally regulated expression of the transmembrane adaptor protein trim in fetal and adult T cells.

Huynh T, Würch A, Bruyns E, Korinek V, Schraven B, Eichmann K.

Scand J Immunol. 2001 Jul-Aug;54(1-2):146-54.

40.

The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.

Kirchgessner H, Dietrich J, Scherer J, Isomäki P, Korinek V, Hilgert I, Bruyns E, Leo A, Cope AP, Schraven B.

J Exp Med. 2001 Jun 4;193(11):1269-84.

41.

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

Brdicka T, Pavlistová D, Leo A, Bruyns E, Korínek V, Angelisová P, Scherer J, Shevchenko A, Hilgert I, Cerný J, Drbal K, Kuramitsu Y, Kornacker B, Horejsí V, Schraven B.

J Exp Med. 2000 May 1;191(9):1591-604.

42.

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway.

Wielenga VJ, Smits R, Korinek V, Smit L, Kielman M, Fodde R, Clevers H, Pals ST.

Am J Pathol. 1999 Feb;154(2):515-23.

43.

Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.

Barker N, Huls G, Korinek V, Clevers H.

Am J Pathol. 1999 Jan;154(1):29-35.

44.

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.

Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H.

Nat Genet. 1998 Aug;19(4):379-83.

PMID:
9697701
45.

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H.

Mol Cell Biol. 1998 Mar;18(3):1248-56.

46.

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.

Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW.

Science. 1997 Mar 21;275(5307):1787-90.

47.

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.

Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H.

Science. 1997 Mar 21;275(5307):1784-7.

48.

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos.

Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, Roose J, Destrée O, Clevers H.

Cell. 1996 Aug 9;86(3):391-9.

49.
50.

Genomic structure of the human CD53 gene.

Korínek V, Horejsí V.

Immunogenetics. 1993;38(4):272-9.

PMID:
8319976

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