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Items: 47

1.

Disability after minor stroke and TIA: A secondary analysis of the SOCRATES trial.

Cucchiara B, George DK, Kasner SE, Knutsson M, Denison H, Ladenvall P, Amarenco P, Johnston SC.

Neurology. 2019 Aug 13;93(7):e708-e716. doi: 10.1212/WNL.0000000000007936. Epub 2019 Jul 11.

PMID:
31296654
2.

Estimated treatment effect of ticagrelor versus aspirin by investigator-assessed events compared with judgement by an independent event adjudication committee in the SOCRATES trial.

Easton JD, Denison H, Evans SR, Knutsson M, Amarenco P, Albers GW, Ladenvall P, Minematsu K, Molina CA, Wang Y, Wong KL, Johnston SC; SOCRATES Steering Committee and Investigators.

Int J Stroke. 2019 May 15:1747493019851282. doi: 10.1177/1747493019851282. [Epub ahead of print]

PMID:
31092152
3.

Time to Loading Dose and Risk of Recurrent Events in the SOCRATES Trial.

Molina CA, Johnston SC, Ladenvall P, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Knutsson M, Minematsu K, Röther J, Wang Y, Wong KSL; SOCRATES Steering Committee and Investigators.

Stroke. 2019 Mar;50(3):675-682. doi: 10.1161/STROKEAHA.118.022675. Erratum in: Stroke. 2019 Apr;50(4):e118.

PMID:
30776996
4.

The Acute Stroke or Transient Ischemic Attack Treated with Ticagrelor and Aspirin for Prevention of Stroke and Death (THALES) trial: Rationale and design.

Johnston SC, Amarenco P, Denison H, Evans SR, Himmelmann A, James S, Knutsson M, Ladenvall P, Molina CA, Wang Y; THALES Investigators.

Int J Stroke. 2019 Feb 12:1747493019830307. doi: 10.1177/1747493019830307. [Epub ahead of print]

PMID:
30747613
5.

Toward decision-based acceptance criteria for Bioanalytical Method Validation: a proposal for discussion from the European Bioanalysis Forum.

Timmerman P, Golob M, Goodman J, Knutsson M, Nelson R, Fjording MS, White S.

Bioanalysis. 2018 Aug 1;10(16):1255-1259. doi: 10.4155/bio-2018-0131. Epub 2018 Aug 21. No abstract available.

6.

Improving selectivity and sensitivity of protein quantitation by LC-HR-MS/MS: determination of somatropin in rat plasma.

Bults P, Meints M, Sonesson A, Knutsson M, Bischoff R, van de Merbel NC.

Bioanalysis. 2018 Jul 1;10(13):1009-1021. doi: 10.4155/bio-2018-0032. Epub 2018 Jun 28.

PMID:
29952231
7.

Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial.

Wong KSL, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Himmelmann A, Kasner SE, Knutsson M, Ladenvall P, Minematsu K, Molina CA, Wang Y, Johnston SC; SOCRATES Steering Committee and Investigators.

Stroke. 2018 Jul;49(7):1678-1685. doi: 10.1161/STROKEAHA.118.020553. Epub 2018 Jun 18.

8.

Tenapanor administration and the activity of the H+ -coupled transporter PepT1 in healthy volunteers.

Johansson S, Rosenbaum DP, Palm J, Stefansson B, Knutsson M, Lisbon EA, Hilgendorf C.

Br J Clin Pharmacol. 2017 Sep;83(9):2008-2014. doi: 10.1111/bcp.13313. Epub 2017 May 31.

9.

Effect of weight reduction on glycated haemoglobin in weight loss trials in patients with type 2 diabetes.

Gummesson A, Nyman E, Knutsson M, Karpefors M.

Diabetes Obes Metab. 2017 Sep;19(9):1295-1305. doi: 10.1111/dom.12971. Epub 2017 May 22. Review.

PMID:
28417575
10.

Effect of Food Intake on the Pharmacodynamics of Tenapanor: A Phase 1 Study.

Johansson SA, Knutsson M, Leonsson-Zachrisson M, Rosenbaum DP.

Clin Pharmacol Drug Dev. 2017 Sep;6(5):457-465. doi: 10.1002/cpdd.341. Epub 2017 Mar 24.

11.

Effects of Tenapanor on Cytochrome P450-Mediated Drug-Drug Interactions.

Johansson S, Rosenbaum DP, Ahlqvist M, Rollison H, Knutsson M, Stefansson B, Elebring M.

Clin Pharmacol Drug Dev. 2017 Sep;6(5):466-475. doi: 10.1002/cpdd.346. Epub 2017 Mar 16.

12.

Effect of Tenapanor on Serum Phosphate in Patients Receiving Hemodialysis.

Block GA, Rosenbaum DP, Leonsson-Zachrisson M, Åstrand M, Johansson S, Knutsson M, Langkilde AM, Chertow GM.

J Am Soc Nephrol. 2017 Jun;28(6):1933-1942. doi: 10.1681/ASN.2016080855. Epub 2017 Feb 3.

13.

Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.

Johansson S, Leonsson-Zachrisson M, Knutsson M, Spencer AG, Labonté ED, Deshpande D, Kohler J, Kozuka K, Charmot D, Rosenbaum DP.

Clin Pharmacol Drug Dev. 2017 Sep;6(5):448-456. doi: 10.1002/cpdd.307. Epub 2016 Oct 26.

14.

A phase 1 study of the safety, tolerability, pharmacodynamics, and pharmacokinetics of tenapanor in healthy Japanese volunteers.

Johansson S, Rosenbaum DP, Knutsson M, Leonsson-Zachrisson M.

Clin Exp Nephrol. 2017 Jun;21(3):407-416. doi: 10.1007/s10157-016-1302-8. Epub 2016 Jul 1.

15.

Effect of Tenapanor on Interdialytic Weight Gain in Patients on Hemodialysis.

Block GA, Rosenbaum DP, Leonsson-Zachrisson M, Stefansson BV, Rydén-Bergsten T, Greasley PJ, Johansson SA, Knutsson M, Carlsson BC.

Clin J Am Soc Nephrol. 2016 Sep 7;11(9):1597-605. doi: 10.2215/CJN.09050815. Epub 2016 Jun 23.

16.

Microscale bioanalysis.

Knutsson M, Timmerman P, Gomez FA.

Bioanalysis. 2016 May;8(9):859-62. doi: 10.4155/bio-2016-0081. No abstract available.

17.

Tiered approach into practice: scientific validation for chromatography-based assays in early development - a recommendation from the European Bioanalysis Forum.

Timmerman P, White S, McDougall S, Kall MA, Smeraglia J, Fjording MS, Knutsson M.

Bioanalysis. 2015 Sep;7(18):2387-2398. doi: 10.4155/bio.15.168. Epub 2015 Sep 10.

18.

Anti-vascular endothelial growth factor therapy in breast cancer.

Kristensen TB, Knutsson ML, Wehland M, Laursen BE, Grimm D, Warnke E, Magnusson NE.

Int J Mol Sci. 2014 Dec 11;15(12):23024-41. doi: 10.3390/ijms151223024. Review.

19.

European Bioanalysis Forum: recommendation for dealing with internal standard variability.

White S, Adcock N, Elbast W, Hiller J, Knutsson M, Lausecker B, Long J, McDougall S, Salavert F, Sangster T, Verhaeghe T, van Amsterdam P.

Bioanalysis. 2014 Oct;6(20):2767-74. doi: 10.4155/bio.14.221.

20.

Feedback from the European Bioanalysis Forum Workshop: taking tiered approach to the next level.

Timmerman P, White S, Knutsson M, Kall MA, Fjording MS, Smeraglia J, McDougall S.

Bioanalysis. 2014;6(19):2593-8. doi: 10.4155/bio.14.224. No abstract available.

PMID:
25411702
21.

Tralokinumab for moderate-to-severe UC: a randomised, double-blind, placebo-controlled, phase IIa study.

Danese S, Rudziński J, Brandt W, Dupas JL, Peyrin-Biroulet L, Bouhnik Y, Kleczkowski D, Uebel P, Lukas M, Knutsson M, Erlandsson F, Hansen MB, Keshav S.

Gut. 2015 Feb;64(2):243-9. doi: 10.1136/gutjnl-2014-308004. Epub 2014 Oct 10.

PMID:
25304132
22.

Oxygen uptake at different intensities and sub-techniques predicts sprint performance in elite male cross-country skiers.

Carlsson M, Carlsson T, Knutsson M, Malm C, Tonkonogi M.

Eur J Appl Physiol. 2014 Dec;114(12):2587-95. doi: 10.1007/s00421-014-2980-0. Epub 2014 Aug 20.

PMID:
25138966
23.

Diacylglycerol acyltransferase 1 inhibition with AZD7687 alters lipid handling and hormone secretion in the gut with intolerable side effects: a randomized clinical trial.

Denison H, Nilsson C, Löfgren L, Himmelmann A, Mårtensson G, Knutsson M, Al-Shurbaji A, Tornqvist H, Eriksson JW.

Diabetes Obes Metab. 2014 Apr;16(4):334-43. doi: 10.1111/dom.12221. Epub 2013 Oct 31.

PMID:
24118885
24.

2013 White Paper on recent issues in bioanalysis: 'hybrid'--the best of LBA and LCMS.

Stevenson L, Garofolo F, DeSilva B, Dumont I, Martinez S, Rocci M, Amaravadi L, Brudny-Kloeppel M, Musuku A, Booth B, Dicaire C, Wright L, Mayrand-Provencher L, Losauro M, Gouty D, Arnold M, Bansal S, Dudal S, Dufield D, Duggan J, Evans C, Fluhler E, Fraser S, Gorovits B, Haidar S, Hayes R, Ho S, Houghton R, Islam R, Jenkins R, Katori N, Kaur S, Kelley M, Knutsson M, Lee J, Liu H, Lowes S, Ma M, Mikulskis A, Myler H, Nicholson B, Olah T, Ormsby E, Patel S, Pucci V, Ray C, Schultz G, Shih J, Shoup R, Simon C, Song A, Neto JT, Theobald V, Thway T, Wakelin-Smith J, Wang J, Wang L, Welink J, Whale E, Woolf E, Xu R.

Bioanalysis. 2013 Dec;5(23):2903-18. doi: 10.4155/bio.13.238. Epub 2013 Oct 10.

25.

LC-MS/MS of large molecules in a regulated bioanalytical environment - which acceptance criteria to apply?

Knutsson M, Schmidt R, Timmerman P.

Bioanalysis. 2013 Sep;5(18):2211-4. doi: 10.4155/bio.13.193. No abstract available.

26.

European Bioanalysis Forum recommendation: scientific validation of quantification by accelerator mass spectrometry.

Higton D, Young G, Timmerman P, Abbott R, Knutsson M, Svensson LD.

Bioanalysis. 2012 Nov;4(22):2669-79. doi: 10.4155/bio.12.242.

27.

2012 white paper on recent issues in bioanalysis and alignment of multiple guidelines.

DeSilva B, Garofolo F, Rocci M, Martinez S, Dumont I, Landry F, Dicaire C, Szekely-Klepser G, Weiner R, Arnold M, Bansal S, Bateman K, Bauer R, Booth B, Davis S, Dudal S, Gouty D, Grundy J, Haidar S, Hayes R, Jemal M, Kaur S, Kelley M, Knutsson M, Le Blaye O, Lee J, Lowes S, Ma M, Mitsuoka T, Neto JT, Nicholson R, Ormsby E, Sailstad J, Stevenson L, Tang D, Welink J, Viswanathan CT, Wang L, Woolf E, Yang E.

Bioanalysis. 2012 Sep;4(18):2213-26. doi: 10.4155/bio.12.205.

28.

Proof of mechanism for the DGAT1 inhibitor AZD7687: results from a first-time-in-human single-dose study.

Denison H, Nilsson C, Kujacic M, Löfgren L, Karlsson C, Knutsson M, Eriksson JW.

Diabetes Obes Metab. 2013 Feb;15(2):136-43. doi: 10.1111/dom.12002. Epub 2012 Sep 30.

PMID:
22950654
29.

Safety, pharmacokinetics and pharmacodynamics of multiple-ascending doses of the novel glucokinase activator AZD1656 in patients with type 2 diabetes mellitus.

Morrow LA, Leonsson-Zachrisson M, Ericsson H, Wollbratt M, Knutsson M, Hompesch M, Norjavaara E.

Diabetes Obes Metab. 2012 Dec;14(12):1114-22. doi: 10.1111/j.1463-1326.2012.01661.x. Epub 2012 Jul 31.

PMID:
22775976
30.

'Less is More': defining modern bioanalysis.

Dijksman J, Timmerman P, Abbott R, Barroso B, Kloeppel MB, Companjen A, Golob M, Gordon B, Herling C, Knutsson M, Luedtke S, Rasmussen BB, Stoellner D, Vieser E, Young G, van Amsterdam P.

Bioanalysis. 2012 Mar;4(6):633-42. doi: 10.4155/bio.12.36.

PMID:
22452252
31.

Anticoagulant counter ion impact on bioanalytical LC-MS/MS assays: results from discussions and experiments within the European Bioanalysis Forum.

Sennbro CJ, Knutsson M, van Amsterdam P, Timmerman P.

Bioanalysis. 2011 Nov;3(21):2393-9. doi: 10.4155/bio.11.239.

PMID:
22074281
32.

Anticoagulant counter ion impact on bioanalytical LC-MS/MS assay performance: additional validation required?

Sennbro CJ, Knutsson M, Timmerman P, van Amsterdam P.

Bioanalysis. 2011 Nov;3(21):2389-91. doi: 10.4155/bio.11.240. No abstract available.

PMID:
22074280
33.

4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease.

Jirholt J, Asling B, Hammond P, Davidson G, Knutsson M, Walentinsson A, Jensen JM, Lehmann A, Agreus L, Lagerström-Fermer M.

PLoS One. 2011 Apr 28;6(4):e19095. doi: 10.1371/journal.pone.0019095.

34.

From challenges to solutions. European Bioanalysis Forum 3rd Annual Open Symposium, Hesperia Towers, Barcelona, Spain, 1-3 December 2010.

Abbott RW, Gordon B, van Amsterdam P, Lausecker B, Brudny-Kloeppel M, Smeraglia J, Romero F, Globig S, Golob M, Knutsson M, Herling C, Vieser E, Timmerman P.

Bioanalysis. 2011 Apr;3(8):833-8. doi: 10.4155/bio.11.52.

35.

Incurred sample reproducibility: views and recommendations by the European Bioanalysis Forum.

Timmerman P, Luedtke S, van Amsterdam P, Brudny-Kloeppel M, Lausecker B, Fischmann S, Globig S, Sennbro CJ, Jansat JM, Mulder H, Thomas E, Knutsson M, Kasel D, White SA, Kall MA, Mokrzycki-Issartel N, Freisleben A, Romero F, Andersen MP, Knebel N, de Zwart M, Laakso S, Hucker RS, Schmidt D, Gordon B, Abbott R, Boulanger P.

Bioanalysis. 2009 Sep;1(6):1049-56. doi: 10.4155/bio.09.108.

36.

Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia.

Asling B, Jirholt J, Hammond P, Knutsson M, Walentinsson A, Davidson G, Agreus L, Lehmann A, Lagerström-Fermer M.

Gut. 2009 Aug;58(8):1063-9. doi: 10.1136/gut.2008.167353. Epub 2009 Apr 26.

37.

The dosing solution influence on the pharmacokinetics of degarelix, a new GnRH antagonist, after s.c. administration to beagle dogs.

Agersø H, Koechling W, Knutsson M, Hjortkjaer R, Karlsson MO.

Eur J Pharm Sci. 2003 Nov;20(3):335-40.

PMID:
14592699
38.

Distribution of mRNA for VIP and PACAP receptors in human cerebral arteries and cranial ganglia.

Knutsson M, Edvinsson L.

Neuroreport. 2002 Mar 25;13(4):507-9.

PMID:
11930171
39.

Vasoactive intestinal peptide has a direct positive inotropic effect on isolated human myocardial trabeculae.

Saetrum Opgaard O, Knutsson M, de Vries R, Tom B, Saxena PR, Edvinsson L.

Clin Sci (Lond). 2001 Dec;101(6):637-43.

PMID:
11724651
40.

Recent high incidence of fulminant hepatitis in Samara, Russia: molecular analysis of prevailing hepatitis B and D virus strains.

Flodgren E, Bengtsson S, Knutsson M, Strebkova EA, Kidd AH, Alexeyev OA, Kidd-Ljunggren K.

J Clin Microbiol. 2000 Sep;38(9):3311-6.

41.

Urine from chronic hepatitis B virus carriers: implications for infectivity.

Knutsson M, Kidd-Ljunggren K.

J Med Virol. 2000 Jan;60(1):17-20.

PMID:
10568757
42.

Novel chiral recognition elements for molecularly imprinted polymer preparation.

Knutsson M, Andersson HS, Nicholls IA.

J Mol Recognit. 1998 Winter;11(1-6):87-90.

PMID:
10076813
43.

On-line supported liquid membrane-liquid chromatography with a phenol oxidase-based biosensor as a selective detection unit for the determination of phenols in blood plasma.

Norberg J, Emnéus JA, Jönsson JA, Mathiasson L, Burestedt E, Knutsson M, Marko-Varga G.

J Chromatogr B Biomed Sci Appl. 1997 Nov 7;701(1):39-46.

PMID:
9389336
44.
45.

Plasma prolactin in relation to menstrual cycle phase, oral contraceptive use, arousal time and smoking habits.

Jernström H, Knutsson M, Taskila P, Olsson H.

Contraception. 1992 Dec;46(6):543-8.

PMID:
1493714
46.

The digestion of starch in the small intestine of dairy cows.

Pehrson B, Johnson U, Knutsson M.

Zentralbl Veterinarmed A. 1981;28(3):241-6. No abstract available.

PMID:
6792834
47.

Glucose and lactose absorption from the small intestine of dairy cows.

Pehrson B, Knutsson M.

Zentralbl Veterinarmed A. 1980;27(8):644-51. No abstract available.

PMID:
6781173

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