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Items: 1 to 50 of 139

1.

Expression of programmed death ligand (PD-L1) in different tumors. Comparison of several current available antibody clones and antibody profiling.

Kintsler S, Cassataro MA, Drosch M, Holenya P, Knuechel R, Braunschweig T.

Ann Diagn Pathol. 2019 Aug;41:24-37. doi: 10.1016/j.anndiagpath.2019.05.005. Epub 2019 May 16.

2.

Multiregion human bladder cancer sequencing reveals tumour evolution, bladder cancer phenotypes and implications for targeted therapy.

Heide T, Maurer A, Eipel M, Knoll K, Geelvink M, Veeck J, Knuechel R, van Essen J, Stoehr R, Hartmann A, Altmueller J, Graham TA, Gaisa NT.

J Pathol. 2019 Jun;248(2):230-242. doi: 10.1002/path.5250. Epub 2019 Mar 18.

PMID:
30719704
3.

Diagnostic and Prognostic Implications of FGFR3high/Ki67high Papillary Bladder Cancers.

Geelvink M, Babmorad A, Maurer A, Stöhr R, Grimm T, Bach C, Knuechel R, Rose M, Gaisa NT.

Int J Mol Sci. 2018 Aug 28;19(9). pii: E2548. doi: 10.3390/ijms19092548.

4.

Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas.

Ferreira MSV, Crysandt M, Braunschweig T, Jost E, Voss B, Bouillon AS, Knuechel R, Brümmendorf TH, Beier F.

Int J Mol Sci. 2018 Feb 18;19(2). pii: E608. doi: 10.3390/ijms19020608.

5.

The role of salvage extended lymph node dissection in patients with rising PSA and PET/CT scan detected nodal recurrence of prostate cancer.

Porres D, Pfister D, Thissen A, Kuru TH, Zugor V, Buettner R, Knuechel R, Verburg FA, Heidenreich A.

Prostate Cancer Prostatic Dis. 2017 Mar;20(1):85-92. doi: 10.1038/pcan.2016.54. Epub 2016 Nov 8.

PMID:
27824042
6.

Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup.

Baldia PH, Maurer A, Heide T, Rose M, Stoehr R, Hartmann A, Williams SV, Knowles MA, Knuechel R, Gaisa NT.

Oncotarget. 2016 Nov 1;7(44):71429-71439. doi: 10.18632/oncotarget.12198.

7.

Strong [(68)Ga]PSMA-HBED-CC accumulation in non-cancerous prostate tissue surrounding a PSMA-negative prostate carcinoma recurrence.

Verburg FA, Behrendt FF, Mottaghy FM, Pfister D, Steib F, Knuechel R.

Nuklearmedizin. 2016 Sep 26;55(5):N44-5. No abstract available.

PMID:
27668299
8.

Erratum to: In situ validation of VEGFR-2 and α v ß 3 integrin as targets for breast lesion characterization.

Ehling J, Misiewicz M, von Stillfried S, Möckel D, Bzyl J, Pochon S, Lederle W, Knuechel R, Lammers T, Palmowski M, Kiessling F.

Angiogenesis. 2016 Jul;19(3):449. No abstract available.

PMID:
27025391
9.

Detection of recurrent prostate cancer lesions before salvage lymphadenectomy is more accurate with (68)Ga-PSMA-HBED-CC than with (18)F-Fluoroethylcholine PET/CT.

Pfister D, Porres D, Heidenreich A, Heidegger I, Knuechel R, Steib F, Behrendt FF, Verburg FA.

Eur J Nucl Med Mol Imaging. 2016 Jul;43(8):1410-7. doi: 10.1007/s00259-016-3366-9. Epub 2016 Mar 19.

PMID:
26993315
10.

In situ validation of VEGFR-2 and α v ß 3 integrin as targets for breast lesion characterization.

Ehling J, Misiewicz M, von Stillfried S, Möckel D, Bzyl J, Pochon S, Lederle W, Knuechel R, Lammers T, Palmowski M, Kiessling F.

Angiogenesis. 2016 Apr;19(2):245-254. doi: 10.1007/s10456-016-9499-4. Epub 2016 Feb 22. Erratum in: Angiogenesis. 2016 Jul;19(3):449.

11.

Differential diagnosis of bladder versus colorectal adenocarcinoma: keratin 7 and GATA3 positivity in nuclear ß-catenin-negative glandular tumours defines adenocarcinoma of the bladder.

Broede A, Oll M, Maurer A, Siegert S, Stoerkel S, Golz R, Schwamborn K, Veeck J, Knuechel R, Gaisa NT; German study group of bladder cancers.

J Clin Pathol. 2016 Apr;69(4):307-12. doi: 10.1136/jclinpath-2015-203144. Epub 2015 Oct 13.

PMID:
26463756
12.

Comparison of structural genetics of non-schistosoma-associated squamous cell carcinoma of the urinary bladder.

Molitor M, Junker K, Eltze E, Toma M, Denzinger S, Siegert S, Knuechel R, Gaisa NT.

Int J Clin Exp Pathol. 2015 Jul 1;8(7):8143-58. eCollection 2015.

13.

Quantitative Micro-Computed Tomography Imaging of Vascular Dysfunction in Progressive Kidney Diseases.

Ehling J, Bábíčková J, Gremse F, Klinkhammer BM, Baetke S, Knuechel R, Kiessling F, Floege J, Lammers T, Boor P.

J Am Soc Nephrol. 2016 Feb;27(2):520-32. doi: 10.1681/ASN.2015020204. Epub 2015 Jul 20.

14.

In cystectomy specimens with bladder cancer whole organ embedding increases the detection rate of histopathological parameters, but not of those with prognostic significance.

Gaisa NT, Wilms H, Wild PJ, Jakse G, Heidenreich A, Knuechel R.

Virchows Arch. 2015 Apr;466(4):423-32. doi: 10.1007/s00428-015-1726-7. Epub 2015 Feb 13.

PMID:
25677977
15.

Cardiac amyloidosis in a heart transplant patient - A case report and retrospective analysis of amyloidosis evolution.

Kintsler S, Jäkel J, Brandenburg V, Kersten K, Knuechel R, Röcken C.

Intractable Rare Dis Res. 2015 Feb;4(1):60-4. doi: 10.5582/irdr.2014.01036.

16.

Fibroblast growth factor receptor (FGFR) gene amplifications are rare events in bladder cancer.

Fischbach A, Rogler A, Erber R, Stoehr R, Poulsom R, Heidenreich A, Schneevoigt BS, Hauke S, Hartmann A, Knuechel R, Veeck J, Gaisa NT.

Histopathology. 2015 Apr;66(5):639-49. doi: 10.1111/his.12473. Epub 2015 Jan 12.

PMID:
24898159
17.

Micro-CT imaging of tumor angiogenesis: quantitative measures describing micromorphology and vascularization.

Ehling J, Theek B, Gremse F, Baetke S, Möckel D, Maynard J, Ricketts SA, Grüll H, Neeman M, Knuechel R, Lederle W, Kiessling F, Lammers T.

Am J Pathol. 2014 Feb;184(2):431-41. doi: 10.1016/j.ajpath.2013.10.014. Epub 2013 Nov 18.

18.

Hepatocyte growth factor-loaded biomaterials for mesenchymal stem cell recruitment.

van de Kamp J, Jahnen-Dechent W, Rath B, Knuechel R, Neuss S.

Stem Cells Int. 2013;2013:892065. doi: 10.1155/2013/892065. Epub 2013 Jun 18.

19.

Levels of acyl-coenzyme A synthetase 5 in urothelial cells and corresponding neoplasias reflect cellular differentiation.

Gaisa NT, Reinartz A, Schneider U, Klaus C, Heidenreich A, Jakse G, Kaemmerer E, Klinkhammer BM, Knuechel R, Gassler N.

Histol Histopathol. 2013 Mar;28(3):353-64. doi: 10.14670/HH-28.353.

PMID:
23348389
20.

Overexpression of SERBP1 (Plasminogen activator inhibitor 1 RNA binding protein) in human breast cancer is correlated with favourable prognosis.

Serce NB, Boesl A, Klaman I, von Serényi S, Noetzel E, Press MF, Dimmler A, Hartmann A, Sehouli J, Knuechel R, Beckmann MW, Fasching PA, Dahl E.

BMC Cancer. 2012 Dec 13;12:597. doi: 10.1186/1471-2407-12-597.

21.

Phase I clinical study of vascular targeting fluorescent cationic liposomes in head and neck cancer.

Strieth S, Dunau C, Kolbow K, Knuechel R, Michaelis U, Ledderose H, Eichhorn ME, Strelczyk D, Tschiesner U, Wollenberg B, Dellian M.

Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1481-7. doi: 10.1007/s00405-012-2185-2. Epub 2012 Sep 27.

PMID:
23015197
22.

Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia.

Oezdemir RF, Gaisa NT, Lindemann-Docter K, Gostek S, Weiskirchen R, Ahrens M, Schwamborn K, Stephan C, Pfister D, Heidenreich A, Knuechel R, Henkel C.

Clin Biochem. 2012 Jan;45(1-2):7-11. doi: 10.1016/j.clinbiochem.2011.09.013. Epub 2011 Oct 2. Erratum in: Clin Biochem. 2012 Nov;45(16-17):1539.

PMID:
21986590
23.

Clonal architecture of human prostatic epithelium in benign and malignant conditions.

Gaisa NT, Graham TA, McDonald SA, Poulsom R, Heidenreich A, Jakse G, Knuechel R, Wright NA.

J Pathol. 2011 Oct;225(2):172-80. doi: 10.1002/path.2959. Epub 2011 Aug 24.

PMID:
21898875
24.

The human urothelium consists of multiple clonal units, each maintained by a stem cell.

Gaisa NT, Graham TA, McDonald SA, Cañadillas-Lopez S, Poulsom R, Heidenreich A, Jakse G, Tadrous PJ, Knuechel R, Wright NA.

J Pathol. 2011 Oct;225(2):163-71. doi: 10.1002/path.2945. Epub 2011 Jul 8.

PMID:
21744343
25.

Individual learning curve reduces the clinical value of urinary cytology.

Strittmatter F, Buchner A, Karl A, Sommer ML, Straub J, Tilki D, Hennenberg M, Knuechel R, Stief CG, Zaak D, Tritschler S.

Clin Genitourin Cancer. 2011 Sep;9(1):22-6. doi: 10.1016/j.clgc.2011.05.007. Epub 2011 Jul 1.

PMID:
21723795
26.

Different immunohistochemical and ultrastructural phenotypes of squamous differentiation in bladder cancer.

Gaisa NT, Braunschweig T, Reimer N, Bornemann J, Eltze E, Siegert S, Toma M, Villa L, Hartmann A, Knuechel R.

Virchows Arch. 2011 Mar;458(3):301-12. doi: 10.1007/s00428-010-1017-2. Epub 2010 Dec 7.

PMID:
21136076
27.

[Video-based teaching in pathology. Experience gained in the last 3 years at the RWTH Aachen University].

Perez-Bouza A, Merk M, Rieck I, Knuechel R.

Pathologe. 2011 May;32(3):244-9. doi: 10.1007/s00292-010-1366-2. German.

PMID:
21046107
28.

Web-based virtual microscopy at the RWTH Aachen University: didactic concept, methods and analysis of acceptance by the students.

Merk M, Knuechel R, Perez-Bouza A.

Ann Anat. 2010 Dec 20;192(6):383-7. doi: 10.1016/j.aanat.2010.01.008. Epub 2010 Mar 15.

PMID:
20363112
29.

The application of artificial intelligence to microarray data: identification of a novel gene signature to identify bladder cancer progression.

Catto JW, Abbod MF, Wild PJ, Linkens DA, Pilarsky C, Rehman I, Rosario DJ, Denzinger S, Burger M, Stoehr R, Knuechel R, Hartmann A, Hamdy FC.

Eur Urol. 2010 Mar;57(3):398-406. doi: 10.1016/j.eururo.2009.10.029. Epub 2009 Nov 6.

30.

The osteogenic differentiation of adult bone marrow and perinatal umbilical mesenchymal stem cells and matrix remodelling in three-dimensional collagen scaffolds.

Schneider RK, Puellen A, Kramann R, Raupach K, Bornemann J, Knuechel R, Pérez-Bouza A, Neuss S.

Biomaterials. 2010 Jan;31(3):467-80. doi: 10.1016/j.biomaterials.2009.09.059. Epub 2009 Oct 7.

PMID:
19815272
31.

Intraoperative photodynamic evaluation of surgical margins during endoscopic extraperitoneal radical prostatectomy with the use of 5-aminolevulinic acid.

Ganzer R, Blana A, Denzinger S, Wieland WF, Adam C, Becker A, Khoder W, Walther S, Stief CG, Zaak D, Salomon G, Hartmann A, Knuechel R, Bertz S, Popken G.

J Endourol. 2009 Sep;23(9):1387-94. doi: 10.1089/end.2009.0374.

PMID:
19673655
32.

Reassessing the current UICC/AJCC TNM staging for renal cell carcinoma.

Moch H, Artibani W, Delahunt B, Ficarra V, Knuechel R, Montorsi F, Patard JJ, Stief CG, Sulser T, Wild PJ.

Eur Urol. 2009 Oct;56(4):636-43. doi: 10.1016/j.eururo.2009.06.036. Epub 2009 Jul 7. Review.

PMID:
19595500
33.

Serum proteomic profiling in patients with bladder cancer.

Schwamborn K, Krieg RC, Grosse J, Reulen N, Weiskirchen R, Knuechel R, Jakse G, Henkel C.

Eur Urol. 2009 Dec;56(6):989-96. doi: 10.1016/j.eururo.2009.02.031. Epub 2009 Mar 6.

PMID:
19282097
34.

Photodynamic diagnosis for superficial bladder cancer: do all risk-groups profit equally from oncological and economic long-term results?

Otto W, Burger M, Fritsche HM, Blana A, Roessler W, Knuechel R, Wieland WF, Denzinger S.

Clin Med Oncol. 2009 Apr 30;3:53-8.

35.

Littoral cell angioma of the spleen mimicking posttransplantation lymphoma in a 63-year-old renal transplant patient.

Mühlfeld AS, Eitner F, Perez-Bouza A, Knuechel R, Heintz B, Floege J.

Am J Kidney Dis. 2008 Sep;52(3):e11-4. doi: 10.1053/j.ajkd.2008.01.033. Epub 2008 May 13.

PMID:
18479795
36.

Photodynamic diagnosis of prostate cancer using 5-aminolevulinic acid--first clinical experiences.

Zaak D, Sroka R, Khoder W, Adam C, Tritschler S, Karl A, Reich O, Knuechel R, Baumgartner R, Tilki D, Popken G, Hofstetter A, Stief CG.

Urology. 2008 Aug;72(2):345-8. doi: 10.1016/j.urology.2007.12.086. Epub 2008 Apr 11.

PMID:
18405945
37.

Artificial intelligence and bladder cancer arrays.

Wild PJ, Catto JW, Abbod MF, Linkens DA, Herr A, Pilarsky C, Wissmann C, Stoehr R, Denzinger S, Knuechel R, Hamdy FC, Hartmann A.

Verh Dtsch Ges Pathol. 2007;91:308-19.

PMID:
18314629
38.

Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis.

Hamm A, Veeck J, Bektas N, Wild PJ, Hartmann A, Heindrichs U, Kristiansen G, Werbowetski-Ogilvie T, Del Maestro R, Knuechel R, Dahl E.

BMC Cancer. 2008 Jan 28;8:25. doi: 10.1186/1471-2407-8-25.

39.

Analyzing effects of photodynamic therapy with 5-aminolevulinic acid (ALA) induced protoporphyrin IX (PPIX) in urothelial cells using reverse phase protein arrays.

Krieg RC, Herr A, Raupach K, Ren Q, Schwamborn K, Knuechel R.

Photochem Photobiol Sci. 2007 Dec;6(12):1296-305. Epub 2007 Aug 9.

PMID:
18046485
40.

Does photodynamic transurethral resection of bladder tumour improve the outcome of initial T1 high-grade bladder cancer? A long-term follow-up of a randomized study.

Denzinger S, Wieland WF, Otto W, Filbeck T, Knuechel R, Burger M.

BJU Int. 2008 Mar;101(5):566-9. Epub 2007 Nov 5.

41.

[Fluorescence cystoscopy at bladder cancer: present trials].

Zaak D, Karl A, Stepp H, Tritschler S, Tilki D, Burger M, Knuechel R, Stief C.

Urologe A. 2007 Nov;46(11):1519-27. Review. German.

PMID:
17928985
42.

Low level STK15 amplification in histologically benign urothelium of patients with bladder cancer adversely predicts patient outcome following cystectomy.

Denzinger S, Stoehr R, Schwarz S, Eichenseher N, Brockhoff G, Obermann EC, Knuechel R, Blaszyk H, Hartmann A, Wild PJ.

Int J Oncol. 2007 Oct;31(4):793-802.

PMID:
17786310
43.

Value of multicolour fluorescence in situ hybridisation (UroVysion) in the differential diagnosis of flat urothelial lesions.

Schwarz S, Rechenmacher M, Filbeck T, Knuechel R, Blaszyk H, Hartmann A, Brockhoff G.

J Clin Pathol. 2008 Mar;61(3):272-7. Epub 2007 Aug 10.

PMID:
17693577
44.

The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation.

Veeck J, Chorovicer M, Naami A, Breuer E, Zafrakas M, Bektas N, Dürst M, Kristiansen G, Wild PJ, Hartmann A, Knuechel R, Dahl E.

Oncogene. 2008 Jan 31;27(6):865-76. Epub 2007 Jul 23.

PMID:
17653090
45.

[Interdisciplinary networking for clinical and molecular questions in non-muscle invasive urothelial carcinoma of the bladder].

Denzinger S, Hartmann A, Hofstaedter F, Knuechel R, Wild PJ, Zaak D, Stief C, Wieland WF, Stoehr R, Burger M.

Urologe A. 2007 Sep;46(9):1126-8. German. No abstract available.

PMID:
17634910
46.

Three-dimensional epidermis-like growth of human mesenchymal stem cells on dermal equivalents: contribution to tissue organization by adaptation of myofibroblastic phenotype and function.

Schneider RK, Neuss S, Stainforth R, Laddach N, Bovi M, Knuechel R, Perez-Bouza A.

Differentiation. 2008 Feb;76(2):156-67. Epub 2007 Jul 18.

PMID:
17634073
47.

Identifying prostate carcinoma by MALDI-Imaging.

Schwamborn K, Krieg RC, Reska M, Jakse G, Knuechel R, Wellmann A.

Int J Mol Med. 2007 Aug;20(2):155-9.

PMID:
17611632
48.

Can an endocytoscope system (ECS) predict histology in neoplastic lesions?

Eberl T, Jechart G, Probst A, Golczyk M, Bittinger M, Scheubel R, Arnholdt H, Knuechel R, Messmann H.

Endoscopy. 2007 Jun;39(6):497-501.

PMID:
17554643
49.
50.

Seven years' experience with 5-aminolevulinic acid in detection of transitional cell carcinoma of the bladder.

Hungerhuber E, Stepp H, Kriegmair M, Stief C, Hofstetter A, Hartmann A, Knuechel R, Karl A, Tritschler S, Zaak D.

Urology. 2007 Feb;69(2):260-4.

PMID:
17320660

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