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Items: 1 to 50 of 117

1.

Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation.

Peri S, Caretti E, Tricarico R, Devarajan K, Cheung M, Sementino E, Menges CW, Nicolas E, Vanderveer LA, Howard S, Conrad P, Crowell JA, Campbell KS, Ross EA, Godwin AK, Yeung AT, Clapper ML, Uzzo RG, Henske EP, Ricketts CJ, Vocke CD, Linehan WM, Testa JR, Bellacosa A, Kopelovich L, Knudson AG.

Oncotarget. 2017 Mar 14;8(11):17628-17642. doi: 10.18632/oncotarget.12192.

2.

Revisiting tissue specificity of germline cancer predisposing mutations.

Maris JM, Knudson AG.

Nat Rev Cancer. 2015 Feb;15(2):65-6.

PMID:
25688405
3.

My memories of Dr. Giovanni Neri.

Knudson AG Jr.

Am J Med Genet A. 2013 Nov;161A(11):2706. doi: 10.1002/ajmg.a.36268. No abstract available.

PMID:
24166812
4.

Meta-analysis identifies NF-κB as a therapeutic target in renal cancer.

Peri S, Devarajan K, Yang DH, Knudson AG, Balachandran S.

PLoS One. 2013 Oct 7;8(10):e76746. doi: 10.1371/journal.pone.0076746. eCollection 2013.

5.

Dosage and tumour suppression.

Berger AH, Knudson AG, Pandolfi PP.

J Pathol. 2012 Jun;227(2):e1; author reply e2. doi: 10.1002/path.4035. No abstract available.

PMID:
22488586
6.

A continuum model for tumour suppression.

Berger AH, Knudson AG, Pandolfi PP.

Nature. 2011 Aug 10;476(7359):163-9. doi: 10.1038/nature10275. Review.

7.

Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations.

Bellacosa A, Godwin AK, Peri S, Devarajan K, Caretti E, Vanderveer L, Bove B, Slater C, Zhou Y, Daly M, Howard S, Campbell KS, Nicolas E, Yeung AT, Clapper ML, Crowell JA, Lynch HT, Ross E, Kopelovich L, Knudson AG.

Cancer Prev Res (Phila). 2010 Jan;3(1):48-61. doi: 10.1158/1940-6207.CAPR-09-0078.

8.

Radiation dose-rate effects, endogenous DNA damage, and signaling resonance.

Vilenchik MM, Knudson AG.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17874-9. Epub 2006 Nov 8.

9.

Improvements in tumor targeting, survivorship, and chemoprevention pioneered by tamoxifen. A personal perspective.

Jordan VC, Knudson AG.

Oncology (Williston Park). 2006 May;20(6):553-62; discussion 567-8, 573, 577. Review.

10.

A personal sixty-year tour of genetics and medicine.

Knudson AG.

Annu Rev Genomics Hum Genet. 2005;6:1-14. Review.

PMID:
16124851
11.

Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations.

Stoyanova R, Clapper ML, Bellacosa A, Henske EP, Testa JR, Ross EA, Yeung AT, Nicolas E, Tsichlis N, Li YS, Linehan WM, Howard S, Campbell KS, Godwin AK, Boman BM, Crowell JA, Kopelovich L, Knudson AG.

Cancer Biol Ther. 2004 Dec;3(12):1313-21. Epub 2004 Dec 9.

PMID:
15662135
12.

Optimized procedures for microarray analysis of histological specimens processed by laser capture microdissection.

Upson JJ, Stoyanova R, Cooper HS, Patriotis C, Ross EA, Boman B, Clapper ML, Knudson AG, Bellacosa A.

J Cell Physiol. 2004 Dec;201(3):366-73.

PMID:
15389559
13.

Use of RNA amplification in the optimal characterization of global gene expression using cDNA microarrays.

Stoyanova R, Upson JJ, Patriotis C, Ross EA, Henske EP, Datta K, Boman B, Clapper ML, Knudson AG, Bellacosa A.

J Cell Physiol. 2004 Dec;201(3):359-65.

PMID:
15389558
14.

Of sea urchins and worms: development and cancer.

Knudson AG.

Cell Death Differ. 2004 Jan;11(1):11-2. No abstract available.

15.

Cancer genetics through a personal retrospectroscope.

Knudson AG.

Genes Chromosomes Cancer. 2003 Dec;38(4):288-91. Review. No abstract available.

PMID:
14566844
16.

Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer.

Vilenchik MM, Knudson AG.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12871-6. Epub 2003 Oct 17.

17.

Cancer genetics.

Knudson AG.

Am J Med Genet. 2002 Jul 22;111(1):96-102. Review.

PMID:
12124744
18.

Two genetic hits (more or less) to cancer.

Knudson AG.

Nat Rev Cancer. 2001 Nov;1(2):157-62. Review.

PMID:
11905807
19.

Chasing the cancer demon.

Knudson AG.

Annu Rev Genet. 2000;34:1-19. Review.

PMID:
11092820
20.

On a new genetic syndrome.

Knudson AG.

Med Pediatr Oncol. 2000 Oct;35(4):428. No abstract available.

PMID:
11025475
21.

Mechanism and relevance of ploidy in neuroblastoma.

Kaneko Y, Knudson AG.

Genes Chromosomes Cancer. 2000 Oct;29(2):89-95. Review.

PMID:
10959087
22.

Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates.

Vilenchik MM, Knudson AG Jr.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5381-6.

23.

Cancer genetics, cytogenetics--defining the enemy within.

Nowell PC, Rowley JD, Knudson AG Jr.

Nat Med. 1998 Oct;4(10):1107-11. No abstract available.

PMID:
9771733
24.

Susumu Ohno: remembrance of things past.

Knudson AG.

Cytogenet Cell Genet. 1998;80(1-4):18-9. No abstract available.

25.

Hereditary predisposition to cancer.

Knudson AG.

Ann N Y Acad Sci. 1997 Dec 29;833:58-67. Review.

PMID:
9616740
26.

Meeting report: genetic environmental interactions in cancer susceptibility in animal models.

Knudson AG, Hino O.

J Natl Cancer Inst. 1997 Nov 19;89(22):1669-72. No abstract available.

PMID:
9390535
27.

Karnofsky Memorial Lecture. Hereditary cancer: theme and variations.

Knudson AG.

J Clin Oncol. 1997 Oct;15(10):3280-7. No abstract available.

PMID:
9336366
28.

Some notes of an IBM-Princess Takamatsu Cancer Research Fund lecturer.

Knudson AG.

Jpn J Cancer Res. 1997 Aug;88(8):785-6. No abstract available.

29.

Eker rat model of a Mendelian dominantly inherited cancer.

Knudson AG.

Jpn J Cancer Res. 1997 Mar;88(3):inside front cover. No abstract available.

PMID:
9162734
30.

Hereditary cancer: two hits revisited.

Knudson AG.

J Cancer Res Clin Oncol. 1996;122(3):135-40. Review.

PMID:
8601560
31.

VHL gene mutation and clear-cell renal carcinomas.

Knudson AG.

Cancer J Sci Am. 1995 Sep-Oct;1(3):180-1. No abstract available.

PMID:
9166471
32.

Hereditary cancers: from discovery to intervention.

Knudson AG Jr.

J Natl Cancer Inst Monogr. 1995;(17):5-7.

PMID:
8573454
33.

Mutation and cancer: a personal odyssey.

Knudson AG Jr.

Adv Cancer Res. 1995;67:1-23. Review. No abstract available.

PMID:
8571812
34.

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene.

Yeung RS, Xiao GH, Jin F, Lee WC, Testa JR, Knudson AG.

Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11413-6.

35.

Genetic predisposition to transplacentally induced renal cell carcinomas in the Eker rat.

Hino O, Mitani H, Knudson AG.

Cancer Res. 1993 Dec 15;53(24):5856-8.

PMID:
8261394
36.

The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19.

Yeung RS, Bell DW, Testa JR, Mayol X, Baldi A, Graña X, Klinga-Levan K, Knudson AG, Giordano A.

Oncogene. 1993 Dec;8(12):3465-8.

PMID:
8247552
37.

Antioncogenes and human cancer.

Knudson AG.

Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):10914-21. Review.

38.

All in the (cancer) family.

Knudson AG.

Nat Genet. 1993 Oct;5(2):103-4. No abstract available.

PMID:
8252032
39.

Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10.

Yeung RS, Buetow KH, Testa JR, Knudson AG Jr.

Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8038-42.

40.

Pediatric molecular oncology. Past as prologue to the future.

Knudson AG Jr.

Cancer. 1993 May 15;71(10 Suppl):3320-4.

PMID:
8490875
41.

Laboratory-clinical interface.

Link MP, Stevens J, Friend SH, Israel MA, Knudson AG, Sondel PM.

Cancer. 1993 May 15;71(10 Suppl):3219-21. No abstract available.

PMID:
8490857
42.

New markers, D16FC1 and Tp12, differentiate between rat chromosomes 16 and 17.

Yeung RS, Taguchi T, Patriotis C, Makris A, Tsichlis PN, Levan KK, Levan G, Tartof K, Hino O, Knudson AG, Testa JR.

Cytogenet Cell Genet. 1993;62(2-3):149-52.

PMID:
8428515
43.

Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer.

Hino O, Klein-Szanto AJ, Freed JJ, Testa JR, Brown DQ, Vilensky M, Yeung RS, Tartof KD, Knudson AG.

Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):327-31.

44.

Introduction to the genetics of primary renal tumors in children.

Knudson AG Jr.

Med Pediatr Oncol. 1993;21(3):193-8. Review.

PMID:
8383279
45.

Assignment of 22 loci in the rat by somatic hybrid and linkage analysis.

Yeung RS, Hino O, Vilensky M, Buetow K, Szpirer C, Szpirer J, Klinga-Levan K, Levan G, Knudson AG.

Mamm Genome. 1993;4(10):585-8.

PMID:
8268657
46.

Stem cell regulation, tissue ontogeny, and oncogenic events.

Knudson AG.

Semin Cancer Biol. 1992 Jun;3(3):99-106. Review.

PMID:
1511159
47.

Heredity and environment in the origin of cancer.

Knudson AG.

Prog Clin Biol Res. 1992;376:31-40. Review. No abstract available.

PMID:
1528925
48.

Localization of the interferon-alpha gene cluster to rat chromosome bands 5q31----q33 by fluorescence in situ hybridization.

Testa JR, Taguchi T, Knudson AG, Hino O.

Cytogenet Cell Genet. 1992;60(3-4):247-9.

PMID:
1505223
49.

Hereditary renal cell carcinoma in the rat associated with nonrandom loss of chromosomes 5 and 6.

Funaki K, Everitt J, Oshimura M, Freed JJ, Knudson AG Jr, Walker C.

Cancer Res. 1991 Aug 15;51(16):4415-22.

50.

Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma.

Walker C, Everitt J, Freed JJ, Knudson AG Jr, Whiteley LO.

Cancer Res. 1991 Jun 1;51(11):2973-8.

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