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Can quality improvement improve the quality of care? A systematic review of reported effects and methodological rigor in plan-do-study-act projects.

Knudsen SV, Laursen HVB, Johnsen SP, Bartels PD, Ehlers LH, Mainz J.

BMC Health Serv Res. 2019 Oct 4;19(1):683. doi: 10.1186/s12913-019-4482-6.


Data Changes Everything: Challenges and Opportunities in Data Visualization Design Handoff.

Walny J, Frisson C, West M, Kosminsky D, Knudsen S, Carpendale S, Willett W.

IEEE Trans Vis Comput Graph. 2019 Aug 27. doi: 10.1109/TVCG.2019.2934538. [Epub ahead of print]


Rapid and high-precision sizing of single particles using parallel suspended microchannel resonator arrays and deconvolution.

Stockslager MA, Olcum S, Knudsen SM, Kimmerling RJ, Cermak N, Payer KR, Agache V, Manalis SR.

Rev Sci Instrum. 2019 Aug;90(8):085004. doi: 10.1063/1.5100861.


Safety and immunogenicity of the chlamydia vaccine candidate CTH522 adjuvanted with CAF01 liposomes or aluminium hydroxide: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.

Abraham S, Juel HB, Bang P, Cheeseman HM, Dohn RB, Cole T, Kristiansen MP, Korsholm KS, Lewis D, Olsen AW, McFarlane LR, Day S, Knudsen S, Moen K, Ruhwald M, Kromann I, Andersen P, Shattock RJ, Follmann F.

Lancet Infect Dis. 2019 Oct;19(10):1091-1100. doi: 10.1016/S1473-3099(19)30279-8. Epub 2019 Aug 12.


Interaction of nutritional status and diabetes on active and latent tuberculosis: a cross-sectional analysis.

Kubiak RW, Sarkar S, Horsburgh CR, Roy G, Kratz M, Reshma A, Knudsen S, Salgame P, Ellner JJ, Drain PK, Hochberg NS.

BMC Infect Dis. 2019 Jul 16;19(1):627. doi: 10.1186/s12879-019-4244-4.


Retinal vessel reactivity is not attenuated in patients with type 2 diabetes compared with matched controls and is associated with peripheral endothelial function in controls.

Baier JM, Funck KL, Petersen L, Vernstrøm L, Knudsen ST, Bek T, Poulsen PL, Laugesen E.

J Diabetes Complications. 2019 Sep;33(9):641-647. doi: 10.1016/j.jdiacomp.2019.05.024. Epub 2019 Jun 3.


Diabetic nephropathy: an insight into molecular mechanisms and emerging therapies.

Warren AM, Knudsen ST, Cooper ME.

Expert Opin Ther Targets. 2019 Jul;23(7):579-591. doi: 10.1080/14728222.2019.1624721. Epub 2019 Jun 3.


Can diabetic polyneuropathy and foot ulcers in patients with type 2 diabetes be accurately identified based on ICD-10 hospital diagnoses and drug prescriptions?

Christensen DH, Knudsen ST, Nicolaisen SK, Andersen H, Callaghan BC, Finnerup NB, Jensen TS, Thomsen RW.

Clin Epidemiol. 2019 May 1;11:311-321. doi: 10.2147/CLEP.S197474. eCollection 2019.


Clinical benefits of switching to insulin degludec irrespective of previous basal insulin therapy in people with Type 1 or Type 2 diabetes: evidence from a European, multicentre, retrospective, non-interventional study (EU-TREAT).

Knudsen ST, Lapolla A, Schultes B, Tentolouris N, Catarig AM, Wolden ML, Siegmund T.

Diabet Med. 2019 Jul;36(7):868-877. doi: 10.1111/dme.13976. Epub 2019 May 2.


A drug response predictor to guide treatment for breast cancer.

Buhl IK, Jensen PB, Kappel Buhl AS, Knudsen S.

Pharmacogenomics. 2019 Apr;20(5):307-309. doi: 10.2217/pgs-2018-0195. Epub 2019 Apr 15. No abstract available.


Hypocretin-deficient narcolepsy patients have abnormal brain activation during humor processing.

Juvodden HT, Alnæs D, Lund MJ, Dietrichs E, Thorsby PM, Westlye LT, Knudsen S.

Sleep. 2019 Jul 8;42(7). pii: zsz082. doi: 10.1093/sleep/zsz082.


Hearing through Your Eyes: Neural Basis of Audiovisual Cross-activation, Revealed by Transcranial Alternating Current Stimulation.

Fassnidge C, Ball D, Kazaz Z, Knudsen S, Spicer A, Tipple A, Freeman E.

J Cogn Neurosci. 2019 Jun;31(6):922-935. doi: 10.1162/jocn_a_01395. Epub 2019 Mar 18.


Switching "Real-World" Diabetes Patients to Degludec from Other Basal Insulins Provides Different Clinical Benefits According to Their Baseline Glycemic Control.

Tentolouris N, Knudsen ST, Lapolla A, Wolden ML, Haldrup S, Schultes B.

Adv Ther. 2019 May;36(5):1201-1210. doi: 10.1007/s12325-019-00916-7. Epub 2019 Mar 16.


CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens.

Pedersen NW, Holm A, Kristensen NP, Bjerregaard AM, Bentzen AK, Marquard AM, Tamhane T, Burgdorf KS, Ullum H, Jennum P, Knudsen S, Hadrup SR, Kornum BR.

Nat Commun. 2019 Feb 19;10(1):837. doi: 10.1038/s41467-019-08774-1.


Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer.

Hamza B, Ng SR, Prakadan SM, Delgado FF, Chin CR, King EM, Yang LF, Davidson SM, DeGouveia KL, Cermak N, Navia AW, Winter PS, Drake RS, Tammela T, Li CM, Papagiannakopoulos T, Gupta AJ, Shaw Bagnall J, Knudsen SM, Vander Heiden MG, Wasserman SC, Jacks T, Shalek AK, Manalis SR.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2232-2236. doi: 10.1073/pnas.1814102116. Epub 2019 Jan 23.


Psychiatric symptoms in patients with post-H1N1 narcolepsy type 1 in Norway.

Nordstrand SEH, Hansen BH, Rootwelt T, Karlsen TI, Swanson D, Nilsen KB, Knudsen S.

Sleep. 2019 Apr 1;42(4). pii: zsz008. doi: 10.1093/sleep/zsz008.


New recommendations for objective investigation of sleep and sleep disorders.

Engstrøm M, Aarrestad S, Eldøen G, Alme A, Bjørge T, Miljeteig H, Bjorvatn B, Knudsen S, Indrekvam S, Nilsen KB.

Tidsskr Nor Laegeforen. 2018 Nov 26;138(19). doi: 10.4045/tidsskr.18.0741. Print 2018 Nov 27. Norwegian. No abstract available.


Comparison of subjective and objective measures of constipation - Employing a new method for categorizing gastrointestinal symptoms.

Grønlund D, Vase L, Knudsen SA, Christensen M, Drewes AM, Olesen AE.

J Pharmacol Toxicol Methods. 2018 Nov - Dec;94(Pt 2):23-28. doi: 10.1016/j.vascn.2018.08.002. Epub 2018 Aug 24.


Predicting efficacy of epirubicin by a multigene assay in advanced breast cancer within a Danish Breast Cancer Cooperative Group (DBCG) cohort: a retrospective-prospective blinded study.

Buhl ASK, Christensen TD, Christensen IJ, Nelausen KM, Balslev E, Knoop AS, Brix EH, Svensson E, Glavicic V, Luczak A, Langkjer ST, Linnet S, Jakobsen EH, Bogovic J, Ejlertsen B, Rasmussen A, Hansen A, Knudsen S, Nielsen D, Jensen PB.

Breast Cancer Res Treat. 2018 Nov;172(2):391-400. doi: 10.1007/s10549-018-4918-4. Epub 2018 Aug 11.


Changes in quality of life in individuals with narcolepsy type 1 after the H1N1-influenza epidemic and vaccination campaign in Norway: a two-year prospective cohort study.

Nordstrand SH, Hansen BH, Kamaleri Y, Nilsen KB, Rootwelt T, Karlsen TI, Knudsen S.

Sleep Med. 2018 Oct;50:175-180. doi: 10.1016/j.sleep.2018.05.037. Epub 2018 Jun 27.


Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives.

Juvodden HT, Alnæs D, Lund MJ, Agartz I, Andreassen OA, Dietrichs E, Thorsby PM, Westlye LT, Knudsen S.

Sleep. 2018 Oct 1;41(10). doi: 10.1093/sleep/zsy145.


Molecular prediction of adjuvant cisplatin efficacy in Non-Small Cell Lung Cancer (NSCLC)-validation in two independent cohorts.

Buhl IK, Santoni-Rugiu E, Ravn J, Hansen A, Christensen IJ, Jensen T, Pratt B, Askaa J, Jensen PB, Knudsen S, Sørensen JB.

PLoS One. 2018 Mar 22;13(3):e0194609. doi: 10.1371/journal.pone.0194609. eCollection 2018.


A 4-miRNA signature to predict survival in glioblastomas.

Hermansen SK, Sørensen MD, Hansen A, Knudsen S, Alvarado AG, Lathia JD, Kristensen BW.

PLoS One. 2017 Nov 14;12(11):e0188090. doi: 10.1371/journal.pone.0188090. eCollection 2017.


Drug response prediction in high-risk multiple myeloma.

Vangsted AJ, Helm-Petersen S, Cowland JB, Jensen PB, Gimsing P, Barlogie B, Knudsen S.

Gene. 2018 Feb 20;644:80-86. doi: 10.1016/j.gene.2017.10.071. Epub 2017 Nov 6.


A European, multicentre, retrospective, non-interventional study (EU-TREAT) of the effectiveness of insulin degludec after switching basal insulin in a population with type 1 or type 2 diabetes.

Siegmund T, Tentolouris N, Knudsen ST, Lapolla A, Prager R, Phan TM, Wolden ML, Schultes B; EU-TREAT study group.

Diabetes Obes Metab. 2018 Mar;20(3):689-697. doi: 10.1111/dom.13149. Epub 2017 Nov 21.


Analysis and manipulation of the induced changes in the state of polarization by mirror scanners.

Petrova-Mayor A, Knudsen S.

Appl Opt. 2017 May 20;56(15):4513-4521. doi: 10.1364/AO.56.004513.


Thinking inside the frame: A framing analysis of the humanities in Danish print news media.

Knudsen S.

Public Underst Sci. 2017 Nov;26(8):908-924. doi: 10.1177/0963662517693452. Epub 2017 Feb 1.


Glucose effectiveness, but not insulin sensitivity, is improved after short-term interval training in individuals with type 2 diabetes mellitus: a controlled, randomised, crossover trial.

Karstoft K, Clark MA, Jakobsen I, Knudsen SH, van Hall G, Pedersen BK, Solomon TPJ.

Diabetologia. 2017 Dec;60(12):2432-2442. doi: 10.1007/s00125-017-4406-0. Epub 2017 Aug 25.


Long-term improvement after combined immunomodulation in early post-H1N1 vaccination narcolepsy.

Viste R, Soosai J, Vikin T, Thorsby PM, Nilsen KB, Knudsen S.

Neurol Neuroimmunol Neuroinflamm. 2017 Aug 7;4(5):e389. doi: 10.1212/NXI.0000000000000389. eCollection 2017 Sep. No abstract available.


Comorbidities in pulmonary tuberculosis cases in Puducherry and Tamil Nadu, India: Opportunities for intervention.

Hochberg NS, Sarkar S, Horsburgh CR Jr, Knudsen S, Pleskunas J, Sahu S, Kubiak RW, Govindarajan S, Salgame P, Lakshminarayanan S, Sivaprakasam A, White LF, Joseph NM, Ellner JJ, Roy G.

PLoS One. 2017 Aug 23;12(8):e0183195. doi: 10.1371/journal.pone.0183195. eCollection 2017.


Population characteristics of a large whale shark aggregation inferred from seawater environmental DNA.

Sigsgaard EE, Nielsen IB, Bach SS, Lorenzen ED, Robinson DP, Knudsen SW, Pedersen MW, Jaidah MA, Orlando L, Willerslev E, Møller PR, Thomsen PF.

Nat Ecol Evol. 2016 Nov 21;1(1):4. doi: 10.1038/s41559-016-0004.


Monitoring of noble, signal and narrow-clawed crayfish using environmental DNA from freshwater samples.

Agersnap S, Larsen WB, Knudsen SW, Strand D, Thomsen PF, Hesselsøe M, Mortensen PB, Vrålstad T, Møller PR.

PLoS One. 2017 Jun 27;12(6):e0179261. doi: 10.1371/journal.pone.0179261. eCollection 2017.


Absence of autoreactive CD4+ T-cells targeting HLA-DQA1*01:02/DQB1*06:02 restricted hypocretin/orexin epitopes in narcolepsy type 1 when detected by EliSpot.

Kornum BR, Burgdorf KS, Holm A, Ullum H, Jennum P, Knudsen S.

J Neuroimmunol. 2017 Aug 15;309:7-11. doi: 10.1016/j.jneuroim.2017.05.001. Epub 2017 May 4.


Programming Post-Translational Control over the Metabolic Labeling of Cellular Proteins with a Noncanonical Amino Acid.

Thomas EE, Pandey N, Knudsen S, Ball ZT, Silberg JJ.

ACS Synth Biol. 2017 Aug 18;6(8):1572-1583. doi: 10.1021/acssynbio.7b00100. Epub 2017 May 17.


Clinical validation of chemotherapy predictors developed on global microRNA expression in the NCI60 cell line panel tested in ovarian cancer.

Prahm KP, Høgdall C, Karlsen MA, Christensen IJ, Novotny GW, Knudsen S, Hansen A, Jensen PB, Jensen T, Mirza MR, Ekmann-Gade AW, Nedergaard L, Høgdall E.

PLoS One. 2017 Mar 23;12(3):e0174300. doi: 10.1371/journal.pone.0174300. eCollection 2017.


Gene expression analysis of decitabine treated AML: high impact of tumor suppressor gene expression changes.

Bohl SR, Dolnik A, Jensen T, Lang KM, Hackanson B, Gaidzik VI, Paschka P, Knudsen S, Döhner K, Döhner H, Claus R, Lübbert M, Bullinger L.

Leuk Lymphoma. 2017 Sep;58(9):1-4. doi: 10.1080/10428194.2017.1287360. Epub 2017 Feb 13. No abstract available.



Kornum BR, Knudsen S, Ollila HM, Pizza F, Jennum PJ, Dauvilliers Y, Overeem S.

Nat Rev Dis Primers. 2017 Feb 9;3:16100. doi: 10.1038/nrdp.2016.100. Review.


The IGF system in patients with type 2 diabetes: associations with markers of cardiovascular target organ damage.

Hjortebjerg R, Laugesen E, Høyem P, Oxvig C, Stausbøl-Grøn B, Knudsen ST, Kim WY, Poulsen PL, Hansen TK, Bjerre M, Frystyk J.

Eur J Endocrinol. 2017 May;176(5):521-531. doi: 10.1530/EJE-16-0940. Epub 2017 Feb 8.


Designing Selectivity in Dirhodium Metallopeptide Catalysts for Protein Modification.

Martin SC, Vohidov F, Wang H, Knudsen SE, Marzec AA, Ball ZT.

Bioconjug Chem. 2017 Feb 15;28(2):659-665. doi: 10.1021/acs.bioconjchem.6b00716. Epub 2017 Jan 17.


Direct single-cell biomass estimates for marine bacteria via Archimedes' principle.

Cermak N, Becker JW, Knudsen SM, Chisholm SW, Manalis SR, Polz MF.

ISME J. 2017 Mar;11(3):825-828. doi: 10.1038/ismej.2016.161. Epub 2016 Dec 6.


Normal Morning Melanin-Concentrating Hormone Levels and No Association with Rapid Eye Movement or Non-Rapid Eye Movement Sleep Parameters in Narcolepsy Type 1 and Type 2.

Schrölkamp M, Jennum PJ, Gammeltoft S, Holm A, Kornum BR, Knudsen S.

J Clin Sleep Med. 2017 Feb 15;13(2):235-243. doi: 10.5664/jcsm.6454.


Environmental DNA from Seawater Samples Correlate with Trawl Catches of Subarctic, Deepwater Fishes.

Thomsen PF, Møller PR, Sigsgaard EE, Knudsen SW, Jørgensen OA, Willerslev E.

PLoS One. 2016 Nov 16;11(11):e0165252. doi: 10.1371/journal.pone.0165252. eCollection 2016.


Assessing the intracellular fate of rhodium(ii) complexes.

Minus MB, Kang MK, Knudsen SE, Liu W, Krueger MJ, Smith ML, Redell MS, Ball ZT.

Chem Commun (Camb). 2016 Sep 22;52(78):11685-11688.


High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays.

Cermak N, Olcum S, Delgado FF, Wasserman SC, Payer KR, A Murakami M, Knudsen SM, Kimmerling RJ, Stevens MM, Kikuchi Y, Sandikci A, Ogawa M, Agache V, Baléras F, Weinstock DM, Manalis SR.

Nat Biotechnol. 2016 Oct;34(10):1052-1059. doi: 10.1038/nbt.3666. Epub 2016 Sep 5.


Input data for inferring species distributions in Kyphosidae world-wide.

Knudsen SW, Clements KD.

Data Brief. 2016 Jul 5;8:1013-7. doi: 10.1016/j.dib.2016.06.043. eCollection 2016 Sep.


Reduced Subendocardial Viability Ratio Is Associated With Unfavorable Cardiovascular Risk Profile in Women With Short Duration of Type 2 Diabetes.

Laugesen E, Høyem P, Fleischer J, Kumarathas I, Knudsen ST, Hansen KW, Christiansen JS, Hansen TK, Poulsen PL.

Am J Hypertens. 2016 Oct;29(10):1165-72. doi: 10.1093/ajh/hpw066. Epub 2016 Jul 12.


Invasively Measured Aortic Systolic Blood Pressure and Office Systolic Blood Pressure in Cardiovascular Risk Assessment: A Prospective Cohort Study.

Laugesen E, Knudsen ST, Hansen KW, Rossen NB, Jensen LO, Hansen MG, Munkholm H, Thomsen KK, Søndergaard H, Bøttcher M, Raungaard B, Madsen M, Hulman A, Witte D, Bøtker HE, Poulsen PL.

Hypertension. 2016 Sep;68(3):768-74. doi: 10.1161/HYPERTENSIONAHA.116.07495. Epub 2016 Jul 11.


Monozygotic twins discordant for narcolepsy type 1 and multiple sclerosis.

Jennum PJ, Kornum BR, Issa NM, Gammeltoft S, Tommerup N, Morling N, Tümer Z, Knudsen S.

Neurol Neuroimmunol Neuroinflamm. 2016 Jun 16;3(4):e249. doi: 10.1212/NXI.0000000000000249. eCollection 2016 Aug. No abstract available.


Molecular, morphological and fossil input data for inferring relationship among viviparous brotulas (Bythitidae) - Resulting in a family status change for Dinematichthyidae.

Knudsen SW, Møller PR, Schwarzhans W, Nielsen JG.

Data Brief. 2016 May 30;8:461-4. doi: 10.1016/j.dib.2016.05.055. eCollection 2016 Sep.


Molecular dissection of valproic acid effects in acute myeloid leukemia identifies predictive networks.

Rücker FG, Lang KM, Fütterer M, Komarica V, Schmid M, Döhner H, Schlenk RF, Döhner K, Knudsen S, Bullinger L.

Epigenetics. 2016 Jul 2;11(7):517-25. doi: 10.1080/15592294.2016.1187350. Epub 2016 Jun 16.

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