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Items: 1 to 50 of 423

1.

Psychometric Properties and Validation of the EMOTICOM Test Battery in a Healthy Danish Population.

Dam VH, Thystrup CK, Jensen PS, Bland AR, Mortensen EL, Elliott R, Sahakian BJ, Knudsen GM, Frokjaer VG, Stenbæk DS.

Front Psychol. 2019 Dec 3;10:2660. doi: 10.3389/fpsyg.2019.02660. eCollection 2019.

2.

Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge.

Erritzoe D, Ashok AH, Searle GE, Colasanti A, Turton S, Lewis Y, Huiban M, Moz S, Passchier J, Saleem A, Beaver J, Lingford-Hughes A, Nutt DJ, Howes OD, Gunn RN, Knudsen GM, Rabiner EA.

Neuropsychopharmacology. 2019 Nov 12. doi: 10.1038/s41386-019-0567-5. [Epub ahead of print]

PMID:
31715617
3.

Radiosynthesis and preclinical evaluation of [11 C]Cimbi-701 - Towards the imaging of cerebral 5-HT7 receptors.

L 'Estrade ET, Shalgunov V, Edgar FG, Strebl-Bantillo MG, Xiong M, Crestey F, Neelamegam R, Dyssegaard A, Lehel S, Erlandsson M, Ohlsson T, Hooker JM, Knudsen GM, Herth MM, Hansen HD.

J Labelled Comp Radiopharm. 2019 Oct 31. doi: 10.1002/jlcr.3808. [Epub ahead of print]

PMID:
31674045
4.

Towards selective CNS PET imaging of the 5-HT7 receptor system: Past, present and future.

L'Estrade ET, Erlandsson M, Edgar FG, Ohlsson T, Knudsen GM, Herth MM.

Neuropharmacology. 2019 Oct 24:107830. doi: 10.1016/j.neuropharm.2019.107830. [Epub ahead of print] Review.

PMID:
31669129
5.

Characterization of the serotonin 2A receptor selective PET tracer (R)-[18F]MH.MZ in the human brain.

Kramer V, Dyssegaard A, Flores J, Soza-Ried C, Rösch F, Knudsen GM, Amaral H, Herth MM.

Eur J Nucl Med Mol Imaging. 2019 Dec 6. doi: 10.1007/s00259-019-04527-w. [Epub ahead of print]

PMID:
31606832
6.

The structure of the serotonin system: A PET imaging study.

Beliveau V, Ozenne B, Strother S, Greve DN, Svarer C, Knudsen GM, Ganz M.

Neuroimage. 2020 Jan 15;205:116240. doi: 10.1016/j.neuroimage.2019.116240. Epub 2019 Oct 7.

7.

Different preprocessing strategies lead to different conclusions: A [11C]DASB-PET reproducibility study.

Nørgaard M, Ganz M, Svarer C, Frokjaer VG, Greve DN, Strother SC, Knudsen GM.

J Cereb Blood Flow Metab. 2019 Oct 1:271678X19880450. doi: 10.1177/0271678X19880450. [Epub ahead of print]

PMID:
31575336
8.

Synthesis and Pharmacological Evaluation of [11C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ-Subunit-Containing γ-Aminobutyric Acid Type A Receptors.

L'Estrade ET, Hansen HD, Falk-Petersen C, Haugaard A, Griem-Krey N, Jung S, Lüddens H, Schirmeister T, Erlandsson M, Ohlsson T, Knudsen GM, Herth MM, Wellendorph P, Frølund B.

ACS Omega. 2019 May 22;4(5):8846-8851. doi: 10.1021/acsomega.9b00434. eCollection 2019 May 31.

9.

Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions.

Johansen A, Holm S, Dall B, Keller S, Kristensen JL, Knudsen GM, Hansen HD.

EJNMMI Res. 2019 Jul 31;9(1):71. doi: 10.1186/s13550-019-0527-4.

10.

In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates.

Prabhakaran J, DeLorenzo C, Zanderigo F, Knudsen GM, Gilling N, Pratap M, Jorgensen MJ, Daunais J, Kaplan JR, Parsey RV, Mann JJ, Kumar D.

J Pharm Pharm Sci. 2019;22(1):352-364. doi: 10.18433/jpps30329.

11.

Microdosing psychedelics: More questions than answers? An overview and suggestions for future research.

Kuypers KP, Ng L, Erritzoe D, Knudsen GM, Nichols CD, Nichols DE, Pani L, Soula A, Nutt D.

J Psychopharmacol. 2019 Sep;33(9):1039-1057. doi: 10.1177/0269881119857204. Epub 2019 Jul 14.

12.

Imaging HDACs In Vivo: Cross-Validation of the [11C]Martinostat Radioligand in the Pig Brain.

Donovan LL, Magnussen JH, Dyssegaard A, Lehel S, Hooker JM, Knudsen GM, Hansen HD.

Mol Imaging Biol. 2019 Jul 9. doi: 10.1007/s11307-019-01403-9. [Epub ahead of print]

PMID:
31290052
13.

Exploratory proteomic analysis implicates the alternative complement cascade in primary CNS vasculitis.

Mandel-Brehm C, Retallack H, Knudsen GM, Yamana A, Hajj-Ali RA, Calabrese LH, Tihan T, Sample HA, Zorn KC, Gorman MP, Madan Cohen J, Sreih AG, Marcus JF, Josephson SA, Douglas VC, Gelfand JM, Wilson MR, DeRisi JL.

Neurology. 2019 Jul 30;93(5):e433-e444. doi: 10.1212/WNL.0000000000007850. Epub 2019 Jul 3.

PMID:
31270218
14.

The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts.

Ivry SL, Knudsen GM, Caiazza F, Sharib JM, Jaradeh K, Ravalin M, O'Donoghue AJ, Kirkwood KS, Craik CS.

Biol Chem. 2019 Nov 26;400(12):1629-1638. doi: 10.1515/hsz-2019-0103.

PMID:
31256057
15.

Optimization of preprocessing strategies in Positron Emission Tomography (PET) neuroimaging: A [11C]DASB PET study.

Nørgaard M, Ganz M, Svarer C, Frokjaer VG, Greve DN, Strother SC, Knudsen GM.

Neuroimage. 2019 Oct 1;199:466-479. doi: 10.1016/j.neuroimage.2019.05.055. Epub 2019 Jun 1.

PMID:
31158479
16.

Automated pupillometry to detect command following in neurological patients: a proof-of-concept study.

Vassilieva A, Olsen MH, Peinkhofer C, Knudsen GM, Kondziella D.

PeerJ. 2019 May 13;7:e6929. doi: 10.7717/peerj.6929. eCollection 2019.

17.

Association Between Sumatriptan Treatment During a Migraine Attack and Central 5-HT1B Receptor Binding.

Deen M, Hougaard A, Hansen HD, Schain M, Dyssegaard A, Knudsen GM, Ashina M.

JAMA Neurol. 2019 Jul 1;76(7):834-840. doi: 10.1001/jamaneurol.2019.0755.

PMID:
31135819
18.

Cortical modulation of pupillary function: systematic review.

Peinkhofer C, Knudsen GM, Moretti R, Kondziella D.

PeerJ. 2019 May 7;7:e6882. doi: 10.7717/peerj.6882. eCollection 2019.

19.

Molecular imaging of neuroinflammation in patients after mild traumatic brain injury: a longitudinal 123 I-CLINDE single photon emission computed tomography study.

Ebert SE, Jensen P, Ozenne B, Armand S, Svarer C, Stenbaek DS, Moeller K, Dyssegaard A, Thomsen G, Steinmetz J, Forchhammer BH, Knudsen GM, Pinborg LH.

Eur J Neurol. 2019 Dec;26(12):1426-1432. doi: 10.1111/ene.13971. Epub 2019 May 21.

PMID:
31002206
20.

Measuring endogenous changes in serotonergic neurotransmission with [11C]Cimbi-36 positron emission tomography in humans.

da Cunha-Bang S, Ettrup A, Mc Mahon B, Skibsted AP, Schain M, Lehel S, Dyssegaard A, Jørgensen LM, Møller K, Gillings N, Svarer C, Knudsen GM.

Transl Psychiatry. 2019 Apr 11;9(1):134. doi: 10.1038/s41398-019-0468-8.

21.

Development and Evaluation of Two Potential 5-HT7 Receptor PET Tracers: [18F]ENL09 and [18F]ENL10.

Tampio L'Estrade E, Xiong M, Shalgunov V, Edgar FG, Volk B, Baerentzen SL, Palner M, Erlandsson M, Ohlsson T, Knudsen GM, Herth MM.

ACS Chem Neurosci. 2019 Sep 18;10(9):3961-3968. doi: 10.1021/acschemneuro.9b00132. Epub 2019 Apr 22.

PMID:
30973705
22.

Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation.

Liu C, Knudsen GM, Pedley AM, He J, Johnson JL, Yaron TM, Cantley LC, Benkovic SJ.

J Proteome Res. 2019 May 3;18(5):2078-2087. doi: 10.1021/acs.jproteome.8b00969. Epub 2019 Apr 18.

PMID:
30964683
23.

Correction to: Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial.

Ott CV, Vinberg M, Bowie CR, Christensen EM, Knudsen GM, Kessing LV, Miskowiak KW.

Trials. 2019 Apr 8;20(1):201. doi: 10.1186/s13063-019-3289-4.

24.

Correction: Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels.

Madsen MK, Fisher PM, Burmester D, Dyssegaard A, Stenbæk DS, Kristiansen S, Johansen SS, Lehel S, Linnet K, Svarer C, Erritzoe D, Ozenne B, Knudsen GM.

Neuropsychopharmacology. 2019 Jun;44(7):1336-1337. doi: 10.1038/s41386-019-0360-5.

25.

Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers.

Erritzoe D, Smith J, Fisher PM, Carhart-Harris R, Frokjaer VG, Knudsen GM.

J Psychopharmacol. 2019 Sep;33(9):1068-1075. doi: 10.1177/0269881119827891. Epub 2019 Feb 28.

PMID:
30816797
26.

Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging.

Stéen EJL, Jørgensen JT, Petersen IN, Nørregaard K, Lehel S, Shalgunov V, Birke A, Edem PE, L'Estrade ET, Hansen HD, Villadsen J, Erlandsson M, Ohlsson T, Yazdani A, Valliant JF, Kristensen JL, Barz M, Knudsen GM, Kjær A, Herth MM.

Bioorg Med Chem Lett. 2019 Apr 15;29(8):986-990. doi: 10.1016/j.bmcl.2019.02.014. Epub 2019 Feb 13.

27.

Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels.

Madsen MK, Fisher PM, Burmester D, Dyssegaard A, Stenbæk DS, Kristiansen S, Johansen SS, Lehel S, Linnet K, Svarer C, Erritzoe D, Ozenne B, Knudsen GM.

Neuropsychopharmacology. 2019 Jun;44(7):1328-1334. doi: 10.1038/s41386-019-0324-9. Epub 2019 Jan 26. Erratum in: Neuropsychopharmacology. 2019 Mar 8;:.

PMID:
30685771
28.

Trait Openness and serotonin 2A receptors in healthy volunteers: A positron emission tomography study.

Stenbaek DS, Kristiansen S, Burmester D, Madsen MK, Frokjaer VG, Knudsen GM, Fisher PM.

Hum Brain Mapp. 2019 May;40(7):2117-2124. doi: 10.1002/hbm.24511. Epub 2019 Jan 11.

PMID:
30633430
29.

Three weeks of SSRI administration enhances the visual perceptual threshold - a randomized placebo-controlled study.

Lansner J, Jensen CG, Petersen A, Fisher PM, Frokjaer VG, Vangkilde S, Knudsen GM.

Psychopharmacology (Berl). 2019 Jun;236(6):1759-1769. doi: 10.1007/s00213-018-5158-3. Epub 2019 Jan 8.

PMID:
30623228
30.

Neuroticism predicts the impact of serotonin challenges on fear processing in subgenual anterior cingulate cortex.

Hornboll B, Macoveanu J, Nejad A, Rowe J, Elliott R, Knudsen GM, Siebner HR, Paulson OB.

Sci Rep. 2018 Dec 17;8(1):17889. doi: 10.1038/s41598-018-36350-y.

31.

Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG (CONNECT-ME): Protocol for a Longitudinal Prospective Study and a Tertiary Clinical Care Service.

Skibsted AP, Amiri M, Fisher PM, Sidaros A, Hribljan MC, Larsen VA, Højgaard JLS, Nikolic M, Hauerberg J, Fabricius ME, Knudsen GM, Møller K, Kondziella D.

Front Neurol. 2018 Nov 27;9:1012. doi: 10.3389/fneur.2018.01012. eCollection 2018.

32.

Influence of Strategic Cortical Infarctions on Pupillary Function.

Peinkhofer C, Martens P, Grand J, Truelsen T, Knudsen GM, Kjaergaard J, Kondziella D.

Front Neurol. 2018 Oct 29;9:916. doi: 10.3389/fneur.2018.00916. eCollection 2018.

33.

Evaluation of [18 F]2FP3 in pigs and non-human primates.

Hansen HD, Constantinescu CC, Barret O, Herth MM, Magnussen JH, Lehel S, Dyssegaard A, Colomb J, Billard T, Zimmer L, Tamagnan G, Knudsen GM.

J Labelled Comp Radiopharm. 2019 Jan;62(1):34-42. doi: 10.1002/jlcr.3692. Epub 2018 Dec 6.

PMID:
30414212
34.

Effects of recombinant human erythropoietin on cognition and neural activity in remitted patients with mood disorders and first-degree relatives of patients with psychiatric disorders: a study protocol for a randomized controlled trial.

Petersen JZ, Schmidt LS, Vinberg M, Jørgensen MB, Hageman I, Ehrenreich H, Knudsen GM, Kessing LV, Miskowiak KW.

Trials. 2018 Nov 6;19(1):611. doi: 10.1186/s13063-018-2995-7.

35.

Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome.

Beekman C, Jiang Z, Suzuki BM, Palmer JM, Lindner DL, O'Donoghue AJ, Knudsen GM, Bennett RJ.

Biol Chem. 2018 Nov 27;399(12):1375-1388. doi: 10.1515/hsz-2018-0240.

PMID:
30367778
36.

Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD.

Deco G, Cruzat J, Cabral J, Knudsen GM, Carhart-Harris RL, Whybrow PC, Logothetis NK, Kringelbach ML.

Curr Biol. 2018 Oct 8;28(19):3065-3074.e6. doi: 10.1016/j.cub.2018.07.083. Epub 2018 Sep 27.

37.

Pre-intervention test-retest reliability of EEG and ERP over four recording intervals.

Ip CT, Ganz M, Ozenne B, Sluth LB, Gram M, Viardot G, l'Hostis P, Danjou P, Knudsen GM, Christensen SR.

Int J Psychophysiol. 2018 Dec;134:30-43. doi: 10.1016/j.ijpsycho.2018.09.007. Epub 2018 Sep 22.

38.

Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial.

Ott CV, Vinberg M, Bowie CR, Christensen EM, Knudsen GM, Kessing LV, Miskowiak KW.

Trials. 2018 Sep 12;19(1):487. doi: 10.1186/s13063-018-2860-8. Erratum in: Trials. 2019 Apr 8;20(1):201.

39.

Low on energy? An energy supply-demand perspective on stress and depression.

Østergaard L, Jørgensen MB, Knudsen GM.

Neurosci Biobehav Rev. 2018 Nov;94:248-270. doi: 10.1016/j.neubiorev.2018.08.007. Epub 2018 Aug 23. Review.

PMID:
30145282
40.

Migraine is associated with high brain 5-HT levels as indexed by 5-HT4 receptor binding.

Deen M, Hougaard A, Hansen HD, Svarer C, Eiberg H, Lehel S, Knudsen GM, Ashina M.

Cephalalgia. 2019 Apr;39(4):526-532. doi: 10.1177/0333102418793642. Epub 2018 Aug 8.

PMID:
30089402
41.

Seasonality-resilient individuals downregulate their cerebral 5-HT transporter binding in winter - A longitudinal combined 11C-DASB and 11C-SB207145 PET study.

Mc Mahon B, Nørgaard M, Svarer C, Andersen SB, Madsen MK, Baaré WFC, Madsen J, Frokjaer VG, Knudsen GM.

Eur Neuropsychopharmacol. 2018 Oct;28(10):1151-1160. doi: 10.1016/j.euroneuro.2018.06.004. Epub 2018 Aug 1.

PMID:
30077433
42.

Does glucagon-like peptide-1 (GLP-1) receptor agonist stimulation reduce alcohol intake in patients with alcohol dependence: study protocol of a randomised, double-blinded, placebo-controlled clinical trial.

Antonsen KK, Klausen MK, Brunchmann AS, le Dous N, Jensen ME, Miskowiak KW, Fisher PM, Thomsen GK, Rindom H, Fahmy TP, Vollstaedt-Klein S, Benveniste H, Volkow ND, Becker U, Ekstrøm C, Knudsen GM, Vilsbøll T, Fink-Jensen A.

BMJ Open. 2018 Jul 16;8(7):e019562. doi: 10.1136/bmjopen-2017-019562.

43.

Classics in Neuroimaging: The Serotonergic 2A Receptor System-from Discovery to Modern Molecular Imaging.

T L'Estrade E, Hansen HD, Erlandsson M, Ohlsson TG, Knudsen GM, Herth MM.

ACS Chem Neurosci. 2018 Jun 20;9(6):1226-1229. doi: 10.1021/acschemneuro.8b00176. Epub 2018 May 15. Review.

PMID:
29763291
44.

Cerebral serotonin transporter measurements with [11C]DASB: A review on acquisition and preprocessing across 21 PET centres.

Nørgaard M, Ganz M, Svarer C, Feng L, Ichise M, Lanzenberger R, Lubberink M, Parsey RV, Politis M, Rabiner EA, Slifstein M, Sossi V, Suhara T, Talbot PS, Turkheimer F, Strother SC, Knudsen GM.

J Cereb Blood Flow Metab. 2019 Feb;39(2):210-222. doi: 10.1177/0271678X18770107. Epub 2018 Apr 13.

PMID:
29651896
45.

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6.

Greninger AL, Knudsen GM, Roychoudhury P, Hanson DJ, Sedlak RH, Xie H, Guan J, Nguyen T, Peddu V, Boeckh M, Huang ML, Cook L, Depledge DP, Zerr DM, Koelle DM, Gantt S, Yoshikawa T, Caserta M, Hill JA, Jerome KR.

BMC Genomics. 2018 Mar 20;19(1):204. doi: 10.1186/s12864-018-4604-2.

46.

Self-perceived personality characteristics in seasonal affective disorder and their implications for severity of depression.

Hjordt LV, Dam VH, Ozenne B, Hageman I, Mc Mahon B, Mortensen EL, Knudsen GM, Stenbæk DS.

Psychiatry Res. 2018 Apr;262:108-114. doi: 10.1016/j.psychres.2018.02.015. Epub 2018 Feb 6.

PMID:
29428773
47.

High brain serotonin levels in migraine between attacks: A 5-HT4 receptor binding PET study.

Deen M, Hansen HD, Hougaard A, Nørgaard M, Eiberg H, Lehel S, Ashina M, Knudsen GM.

Neuroimage Clin. 2018 Jan 28;18:97-102. doi: 10.1016/j.nicl.2018.01.016. eCollection 2018.

48.

Amygdala response to emotional faces in seasonal affective disorder.

Borgsted C, Ozenne B, Mc Mahon B, Madsen MK, Hjordt LV, Hageman I, Baaré WFC, Knudsen GM, Fisher PM.

J Affect Disord. 2018 Mar 15;229:288-295. doi: 10.1016/j.jad.2017.12.097. Epub 2018 Jan 3.

PMID:
29329062
49.

Amygdala reactivity to fearful faces correlates positively with impulsive aggression.

da Cunha-Bang S, Fisher PM, Hjordt LV, Holst K, Knudsen GM.

Soc Neurosci. 2019 Apr;14(2):162-172. doi: 10.1080/17470919.2017.1421262. Epub 2018 Jan 7.

PMID:
29271284
50.

The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions.

Johansen A, Hansen HD, Svarer C, Lehel S, Leth-Petersen S, Kristensen JL, Gillings N, Knudsen GM.

J Cereb Blood Flow Metab. 2018 Apr;38(4):659-668. doi: 10.1177/0271678X17746179. Epub 2017 Dec 7.

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